Epidemiology at Edinburgh integrates behaviour, genomics and health‑systems research to map transmission, quantify burden and translate evidence into fair, effective public‑health action. Work within this theme quantifies disease burden and risk, models transmission dynamics and anticipates outbreaks by integrating behavioural science, clinical data, and the genetics and genomics of hosts and pathogens. The theme draws on expertise spanning ecology, genetics, veterinary science, social science, and public health — reflecting the complexity of the challenges being addressed and the value of interdisciplinary collaboration.ModellingAt the heart of this work is a strong tradition of mathematical and computational modelling. Researchers use phylogenetics, Bayesian inference, and machine learning to reconstruct how pathogens evolve and spread — from avian influenza and emerging RNA viruses to HIV transmission networks. This quantitative expertise is complemented by field epidemiology and experimental laboratory work.One Health approachesMuch of the research takes a One Health approach, recognising that human, animal, and environmental health are deeply interconnected. Research spans diseases at the wildlife-livestock-human interface, including rabies, trypanosomiasis, tuberculosis, and zoonotic infections. Several researchers work extensively in sub-Saharan Africa and other low- and middle-income settings, addressing diseases with significant global burden.Societal impactResearch examines determinants of health and healthcare access, revealing social and structural drivers that shape exposure, outcomes and equity. Advanced surveillance, outbreak investigation and risk analysis inform targeted, proportionate responses in communities and health systems locally and globally. This expertise was crucial and highly impactful during the Covid-19 pandemic. Behaviour change insights enhance intervention design and delivery, while co‑production with stakeholders continues to inform policy decisions that are data‑driven, context‑sensitive and fair. Researchers within this theme NameAffiliationHelen AlexanderSchool of Biological SciencesNeil AndersonRoslin InstituteKatie AtkinsUsher InstituteCharalampos AttipaRoyal (Dick) School of Veterinary StudiesGeoffrey BandaSchool of Social and Political ScienceMark BronsvoortRoslin InstituteSarah BurtheCentre for Ecology and HydrologyHarry CampbellUsher InstituteEmma CunninghamSchool of Biological SciencesAndrea Doeschl-WilsonRoslin InstituteXavier DonadeuRoslin InstituteJaime Garcia IglesiasUsher InstituteRowland KaoRoslin InstituteAndrew Leigh-BrownSchool of Biological SciencesLu LuRoslin InstituteSam LycettRoslin InstituteGlenn MarionBiomathematics and Statistics ScotlandStella MazeriRoslin InstituteFrancisca MutapiSchool of Biological SciencesHarish NairUsher InstituteJames PrendergastRoslin InstituteAndrew RambautSchool of Biological SciencesNick SavillSchool of Biological SciencesDarren ShawRoyal (Dick) School of Veterinary StudiesTing ShiUsher InstituteMatt SilkSchool of Biological SciencesLesley SmithScotland's Rural CollegeMark WoolhouseUsher Institute This article was published on Monday 23 March 2026