Recent publications

Recent publications in PubMed

 

August 2020

Host circadian clocks do not set the schedule for the within-host replication of malaria parasites.  Aidan J O'Donnell  1 , Kimberley F Prior  1 , Sarah E Reece.  Proc Biol Sci. 2020 Aug 12;287(1932):20200347.doi: 10.1098/rspb.2020.0347. Epub 2020 Aug 12.

Influence of hepatitis C virus co-infection and hepatitis C virus treatment on risk of chronic kidney disease in HIV-positive persons.  Amanda Mocroft  1 , Lene Ryom  2 , Cristiana Oprea  3 , Qiuju Li  1 , Andri Rauch  4 , Christoph Boesecke  5 , Vilma Uzdaviniene  6 , Dalibor Sedlacek  7 , Josep M Llibre  8 , Karine Lacombe  9 , Lars N Nielsen  10 , Eric Florence  11 , Inka Aho et al.  AIDS. 2020 Aug 1;34(10):1485-1495.doi: 10.1097/QAD.0000000000002570.

Acapsular Staphylococcus aureus with a non-functional agr regains capsule expression after passage through the bloodstream in a bacteremia mouse model.  Carlos M Suligoy  1 , Rocío E Díaz  1 , Ana-Katharina Gehrke  2 , Natalie Ring  3 , Gonzalo Yebra  3 , Joana Alves  3 , Marisa I Gómez  2 , Sindy Wendler  4 , J Ross Fitzgerald  3 , Lorena Tuchscherr  4 , Bettina Löffler  4 , Daniel O Sordelli et al.  Sci Rep. 2020 Aug 24;10(1):14108.doi: 10.1038/s41598-020-70671-1.

Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020.  Erik Alm  1 , Eeva K Broberg  1 , Thomas Connor  2   3 , Emma B Hodcroft  4 , Andrey B Komissarov  5 , Sebastian Maurer-Stroh  6   7   8   9 , Angeliki Melidou  1 , Richard A Neher  4 , Áine O'Toole  10 , Dmitriy Pereyaslov  et al.  Euro Surveill. 2020 Aug;25(32):2001410. doi: 10.2807/1560-7917.ES.2020.25.32.2001410.

Limitation of spiral microchannels for particle separation in heterogeneous mixtures: Impact of particles' size and deformability.  Ewa Guzniczak  1 , Timm Krüger  2 , Helen Bridle  1 , Melanie Jimenez. Biomicrofluidics. 2020 Aug 10;14(4):044113. doi: 10.1063/5.0009673. eCollection 2020 Jul.

Quorum sensing in African trypanosomes.  Federico Rojas  1 , Keith R Matthews.  Curr Opin Microbiol. 2019 Dec;52:124-129.doi: 10.1016/j.mib.2019.07.001. Epub 2019 Aug 20.

Positive impact of preventative chemotherapy during a national helminth control program: Perception and KAP.  Francisca Mutapi  1   2 , Paradzayi Tagwireyi  3 , Rivka Lim  1   2 , Blessing Mangwanda  3 , Charmaine Fourier  4 , Takafira Mduluza.  PLoS Negl Trop Dis. 2020 Aug 24;14(8):e0008494.doi: 10.1371/journal.pntd.0008494. eCollection 2020 Aug.

Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria - a systematic review for the EAACI Biologicals Guidelines.  Ioana Agache  1 , Claudio Rocha  2 , Ana Pereira  2 , Yang Song  2 , Pablo Alonso-Coello  3   4 , Ivan Solà  2 , Jessica Beltran  2 , Margarita Posso  3 , Cezmi Akdis  5   6 , Mubeccel Akdis  5   6 , Knut Brockow  7 , Tomas Chivato  8 , Stefano Del Giacco et al.  Allergy. 2020 Aug 7.doi: 10.1111/all.14547. Online ahead of print.

Assessing the effect of insecticide-treated cattle on tsetse abundance and trypanosome transmission at the wildlife-livestock interface in Serengeti, Tanzania.  Jennifer S Lord  1 , Rachel S Lea  1 , Fiona K Allan  2 , Mechtilda Byamungu  3 , David R Hall  4 , Jessica Lingley  1 , Furaha Mramba  3 , Edith Paxton  2 , Glyn A Vale  4   5 , John W Hargrove  5 , Liam J Morrison  2 , Stephen J Torr  1 , Harriet K Auty.  PLoS Negl Trop Dis. 2020 Aug 25;14(8):e0008288.doi: 10.1371/journal.pntd.0008288. eCollection 2020 Aug.

Global variability of the human IgG glycome.  Jerko Štambuk  1 , Natali Nakić  2 , Frano Vučković  1 , Maja Pučić-Baković  1 , Genadij Razdorov  1 , Irena Trbojević-Akmačić  1 , Mislav Novokmet  1 , Toma Keser  3 , Marija Vilaj  1 , Tamara Štambuk  3 , Ivan Gudelj  1 , Mirna Šimurina  3 , Manshu Song et al.  Aging (Albany NY). 2020 Aug 12;12.doi: 10.18632/aging.103884. Online ahead of print.

Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial.  Justin J Chu  1 , Adam J Devall  2 , Leanne E Beeson  3 , Pollyanna Hardy  3 , Versha Cheed  3 , Yongzhong Sun  3 , Tracy E Roberts  3 , C Okeke Ogwulu  3 , Eleanor Williams  3 , Laura L Jones  3 , Jenny H La Fontaine Papadopoulos et al.  Lancet. 2020 Sep 12;396(10253):770-778.doi: 10.1016/S0140-6736(20)31788-8. Epub 2020 Aug 24.

Helminth extracellular vesicles: great balls of wonder.  Karl F Hoffmann  1 , Cornelis H Hokke  2 , Alex Loukas  3 , Amy H Buck.  Int J Parasitol. 2020 Aug;50(9):621-622.doi: 10.1016/j.ijpara.2020.07.002. 

Cytosolic Invertase-Mediated Root Growth Is Feedback-Regulated by A Glucose-Dependent Signaling Loop.  Lai-Sheng Meng  1 , Zhi-Qin Wei  2 , Xiao-Ying Cao  2 , Chen Tong  2 , Meng-Jiao Lv  2 , Fei Yu  2 , Gary J Loake.  Plant Physiol. 2020 Aug 20;pp.00778.2020.doi: 10.1104/pp.20.00778. Online ahead of print.

Identification of a functional small non-coding RNA encoded by African swine fever virus.  Laura E M Dunn  1   2 , Alasdair Ivens  3 , Christopher L Netherton  1 , David A G Chapman  1 , Philippa M Beard.  J Virol. 2020 Aug 12;JVI.01515-20. doi: 10.1128/JVI.01515-20. Online ahead of print. 

Pain workshop ESMO: Africa (response).  Liz Grant  1 , Mhoira Leng  2 , Marie Fallon.  ESMO Open. 2020 Aug;5(4):e000833. doi: 10.1136/esmoopen-2020-000833.

The Pathogenesis of Fungal-Related Diseases and Allergies in the African Population: The State of the Evidence and Knowledge Gaps.  Lorraine Tsitsi Pfavayi  1   2 , Elopy Nimele Sibanda  3   4   5 , Francisca Mutapi.  Int Arch Allergy Immunol. 2020;181(4):257-269.doi: 10.1159/000506009. Epub 2020 Feb 18.

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis.  Nicole D Barth  1 , Ramon Subiros-Funosas  1 , Lorena Mendive-Tapia  1 , Rodger Duffin  1 , Mario A Shields  2 , Jennifer A Cartwright  1 , Sónia Troeira Henriques  3   4 , Jesus Sot  5 , Felix M Goñi  5 , Rodolfo Lavilla  6 , John A Marwick et al.  Nat Commun. 2020 Aug 12;11(1):4027.doi: 10.1038/s41467-020-17772-7.

Morphological, Molecular Identification and Distribution of Trypanosome-Transmitting Dipterans from Cattle Settlements in Southwest Nigeria.  Paul Olalekan Odeniran  1   2 , Ewan Thomas Macleod  3 , Isaiah Oluwafemi Ademola  4 , John Asekhaen Ohiolei  5 , Ayodele Oluwakemi Majekodunmi  3   6 , Susan Christina Welburn.  Acta Parasitol. 2020 Aug 11.doi: 10.1007/s11686-020-00260-9. Online ahead of print.

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.  Peter J Harrison  1   2   3 , Kenneth Gable  4 , Niranjanakumari Somashekarappa  4 , Van Kelly  1 , David J Clarke  1 , James H Naismith  2   3   5 , Teresa M Dunn  4 , Dominic J Campopiano.  J Lipid Res. 2019 May;60(5):953-962.doi: 10.1194/jlr.M089367. Epub 2019 Feb 21.

Secondary Bacterial Infections in Patients With Viral Pneumonia.  Prasanth Manohar  1   2 , Belinda Loh  1 , Ramesh Nachimuthu  3 , Xiaoting Hua  4   5 , Susan C Welburn  1   6 , Sebastian Leptihn.  Front Med (Lausanne). 2020 Aug 5;7:420.doi: 10.3389/fmed.2020.00420. eCollection 2020.

Genesis and spread of multiple reassortants during the 2016/2017 H5 avian influenza epidemic in Eurasia.  Samantha J Lycett  1 , Anne Pohlmann  2 , Christoph Staubach  3 , Valentina Caliendo  4 , Mark Woolhouse  5 , Martin Beer  2 , Thijs Kuiken  6 , Global Consortium for H5N8 and Related Influenza Viruses.  Proc Natl Acad Sci U S A. 2020 Aug 7;202001813.doi: 10.1073/pnas.2001813117. Online ahead of print.

Respiratory research funding is inadequate, inequitable, and a missed opportunity.  Siân Williams  1 , Aziz Sheikh  2 , Harry Campbell  2 , Neil Fitch  3 , Chris Griffiths  4 , Robert S Heyderman  5 , Rachel E Jordan  6 , S Vittal Katikireddi  7 , Ioanna Tsiligianni  8 , Angela Obasi  9 , Global Health Respiratory Network.  Lancet Respir Med. 2020 Aug;8(8):e67-e68. doi: 10.1016/S2213-2600(20)30329-5. 

Psoroptes ovis-Early Immunoreactive Protein (Pso-EIP-1) a novel diagnostic antigen for sheep scab.  Stewart T G Burgess  1 , Francesca Nunn  1 , Kath Bartley  1 , David Frew  1 , Kevin McLean  1 , Neil F Inglis  1 , Kara McGeachy  2 , Michael E Taliansky  2   3 , Andrew J Love  2 , Andrew J Nisbet.  Parasite Immunol. 2020 Aug 27;e12788.doi: 10.1111/pim.12788. Online ahead of print.

Early Life Microbiota and Respiratory Tract Infections.  Wouter A A de Steenhuijsen Piters  1 , Justyna Binkowska  2 , Debby Bogaert.  Cell Host Microbe. 2020 Aug 12;28(2):223-232.doi: 10.1016/j.chom.2020.07.004.

July 2020

COVID-19: potential transmission through aerosols in surgical procedures and blood products. A Hamish R W Simpson, Graham Dall, Jürgen G Haas .  Bone Joint Res. 2020 Jul 23;9(4):200-201. doi: 10.1302/2046-3758.94.BJR-2020-0130. eCollection 2020 Apr.

Rapid and sensitive direct detection and identification of poliovirus from stool and environmental surveillance samples using nanopore sequencing.  Alexander G Shaw  1 , Manasi Majumdar  2 , Catherine Troman  3 , Áine O'Toole  4 , Blossom Benny  5 , Dilip Abraham  5 , Ira Praharaj  6 , Gagandeep Kang  5 , Salmaan Sharif  7 , Muhammad Masroor Alam  7 , Shahzad Shaukat  7 , Mehar Angez et al.  J Clin Microbiol. 2020 Jul 1;JCM.00920-20.doi: 10.1128/JCM.00920-20. Online ahead of print.

Contribution of segment 3 to the acquisition of virulence in contemporary H9N2 avian influenza viruses.  Anabel L Clements, Joshua E Sealy, Thomas P Peacock, Jean-Remy Sadeyen, Saira Hussain, Samantha J Lycett, Holly Shelton, Paul Digard, Munir Iqbal.  J Virol. 2020 Jul 29;JVI.01173-20.doi: 10.1128/JVI.01173-20. Online ahead of print.

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.  Andrew D Bretherick  1 , Oriol Canela-Xandri  1   2 , Peter K Joshi  3 , David W Clark  3 , Konrad Rawlik  2 , Thibaud S Boutin  1 , Yanni Zeng  1   4   5   6 , Carmen Amador  1 , Pau Navarro  1 , Igor Rudan  3 , Alan F Wright  1 , Harry Campbell et al.  PLoS Genet. 2020 Jul 6;16(7):e1008785.doi: 10.1371/journal.pgen.1008785. eCollection 2020 Jul.  

A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology.  Andrew Rambaut  1 , Edward C Holmes  2 , Áine O'Toole  3 , Verity Hill  3 , John T McCrone  3 , Christopher Ruis  4 , Louis du Plessis  5 , Oliver G Pybus.  Nat Microbiol. 2020 Jul 15.doi: 10.1038/s41564-020-0770-5. Online ahead of print.

The transcriptional signature associated with human motile cilia.  Anirudh Patir  1 , Amy M Fraser  1 , Mark W Barnett  1 , Lynn McTeir  1 , Joe Rainger  1 , Megan G Davey  1 , Tom C Freeman.  Sci Rep. 2020 Jul 2;10(1):10814.doi: 10.1038/s41598-020-66453-4.

A high-throughput genomic screen identifies a role for the plasmid-borne type II secretion system of Escherichia coli O157:H7 (Sakai) in plant-microbe interactions.  Ashleigh Holmes  1 , Leighton Pritchard  2 , Peter Hedley  1 , Jenny Morris  1 , Sean P McAteer  3 , David L Gally  3 , Nicola J Holden.  Genomics. 2020 Jul 11;S0888-7543(20)30411-0.doi: 10.1016/j.ygeno.2020.07.021. Online ahead of print.

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands.  Bas B Oude Munnink  1 , David F Nieuwenhuijse  1 , Mart Stein  2 , Áine O'Toole  3 , Manon Haverkate  2 , Madelief Mollers  2 , Sandra K Kamga  2 , Claudia Schapendonk et al.  Nat Med. 2020 Jul 16.doi: 10.1038/s41591-020-0997-y. Online ahead of print.

A matrix metalloproteinase activation probe for painting human tumours.  Bethany Mills  1 , Dominic Norberg  1 , Kevin Dhaliwal  1 , Ahsan R Akram  1 , Mark Bradley  2 , Alicia Megia-Fernandez.  Chem Commun (Camb). 2020 Jul 23.doi: 10.1039/d0cc03886e. Online ahead of print.

Non-steroidal anti-inflammatory drugs, prostaglandins and COVID-19.  Calum T Robb  1 , Marie Goepp  1 , Adriano G Rossi  1 , Chengcan Yao.  Br J Pharmacol. 2020 Jul 23.doi: 10.1111/bph.15206. Online ahead of print.

Cancer has not gone away: A primary care perspective to support a balanced approach for timely cancer diagnosis during COVID-19.  Charles W Helsper  1 , Christine Campbell  2 , Jon Emery  3 , Richard D Neal  4 , Li Li  5 , Greg Rubin  6 , Henk van Weert  7 , Peter Vedsted  8 , Fiona M Walter  9 , David Weller  2 , Larissa Nekhlyudov.  Eur J Cancer Care (Engl). 2020 Jul 7;e13290. doi: 10.1111/ecc.13290. Online ahead of print.

Erratum for Burkard et al., "Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection".  Christine Burkard  1 , Tanja Opriessnig  1   2 , Alan J Mileham  3 , Tomasz Stadejek  4 , Tahar Ait-Ali  1 , Simon G Lillico  1 , C Bruce A Whitelaw  1 , Alan L Archibald.  J Virol. 2020 Jul 16;94(15):e00951-20.doi: 10.1128/JVI.00951-20. Print 2020 Jul 16.

Evolution and epidemic spread of SARS-CoV-2 in Brazil.  Darlan S Candido #  1   2 , Ingra M Claro #  2   3 , Jaqueline G de Jesus #  2   3 , William M Souza #  4 , Filipe R R Moreira #  5 , Simon Dellicour #  6   7 , Thomas A Mellan #  8 , Louis du Plessis et al.  Science. 2020 Jul 23;eabd2161. doi: 10.1126/science.abd2161. Online ahead of print.

100 years of influenza research seen through the lens of Covid-19.  Debby Bogaert, David H Dockrell.  Mucosal Immunol. 2020 Jul;13(4):561-562.doi: 10.1038/s41385-020-0291-9. Epub 2020 May 1.

US decision to pull out of World Health Organization.  Devi Sridhar, Lois King.  BMJ. 2020 Jul 24;370:m2943.doi: 10.1136/bmj.m2943.

Single-Cell Bacterial Electrophysiology Reveals Mechanisms of Stress-Induced Damage.  Ekaterina Krasnopeeva  1 , Chien-Jung Lo  2 , Teuta Pilizota.  Biophys J. 2019 Jun 18;116(12):2390-2399.doi: 10.1016/j.bpj.2019.04.039. Epub 2019 May 15.

Bacterial flagellar motor as a multimodal biosensor.  Ekaterina Krasnopeeva  1 , Uriel E Barboza-Perez  1 , Jerko Rosko  2 , Teuta Pilizota  3 , Chien-Jung Lo.  Methods. 2020 Jul 5;S1046-2023(20)30132-8.doi: 10.1016/j.ymeth.2020.06.012. Online ahead of print.

Niche- and gender-dependent immune reactions in relation to the microbiota profile in pediatric patients with otitis media with effusion.  Frida Enoksson  1 , Alicia Ruiz Rodriguez  2 , Chikondi Peno  2 , Carlos Balcazar Lopez  2 , Fredrik Tjernström  3 , Debby Bogaert  2 , Anders P Hakansson  4 , Caroline Bergenfelz.  Infect Immun. 2020 Jul 13;IAI.00147-20.doi: 10.1128/IAI.00147-20. Online ahead of print.

RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a randomised controlled trial.  Gavin D Perkins  1   2 , Keith Couper  1   2 , Bronwen Connolly  3 , J Kenneth Baillie  4   5 , Judy M Bradley  3 , Paul Dark  6 , Anthony De Soyza  7   8 , Ellen Gorman  3 , Alasdair Gray  9   10 , Louisa Hamilton  1 , Nicholas Hart et al.  Trials. 2020 Jul 29;21(1):687. doi: 10.1186/s13063-020-04617-3.

Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells.  Helen K Alexander  1   2 , R Craig MacLean.  Proc Natl Acad Sci U S A. 2020 Jul 23;201919672.doi: 10.1073/pnas.1919672117. Online ahead of print.

Measuring and reporting treatment adherence: what can we learn by comparing two respiratory conditions? Holly Tibble  1   2 , Mary Flook  1 , Aziz Sheikh  1   2   3 , Athanasios Tsanas  1   2 , Rob Horne  2   4 , Bernard Vrijens  5   6 , Sabina De Geest  7   8 , Helen R Stagg.  Br J Clin Pharmacol. 2020 Jul 8.doi: 10.1111/bcp.14458. Online ahead of print.

Efficacy and safety of dupilumab for moderate-to-severe atopic dermatitis: a systematic review for the EAACI Biologicals Guidelines.  Ioana Agache  1 , Yang Song  2 , Margarita Posso  2   3 , Pablo Alonso-Coello  3   4 , Claudio Rocha  2 , Ivan Solà  2 , Jessica Beltran  2 , Cezmi Akdis  5   6 , Mubeccel Akdis  5   6 , Knut Brockow et al.  Allergy. 2020 Jul 21.doi: 10.1111/all.14510. Online ahead of print. 

Eosinophil Deficiency Promotes Aberrant Repair and Adverse Remodeling Following Acute Myocardial Infarction.  Iqbal S Toor  1 , Dominik Rückerl  2 , Iris Mair  3 , Rob Ainsworth  4 , Marco Meloni  1 , Ana-Mishel Spiroski  1 , Cecile Benezech  1 , Jennifer M Felton  3 , Adrian Thomson  1 , Andrea Caporali et al.  JACC Basic Transl Sci. 2020 Jul 8;5(7):665-681.doi: 10.1016/j.jacbts.2020.05.005. eCollection 2020 Jul.

Daphnia magna modifies its gene expression extensively in response to caloric restriction revealing a novel effect on haemoglobin isoform preference.  Jack Hearn  1 , Jessica Clark  2 , Philip J Wilson  3 , Tom J Little.  Mol Ecol. 2020 Jul 20.doi: 10.1111/mec.15557. Online ahead of print. 

Changes in the Ileal, but Not Fecal, Microbiome in Response to Increased Dietary Protein Level and Enterotoxigenic Escherichia coli Exposure in Pigs.  Jolinda Pollock  1   2 , Michael R Hutchings  3 , Kate E K Hutchings  3 , David L Gally  2 , Jos G M Houdijk.  Appl Environ Microbiol. 2019 Sep 17;85(19):e01252-19.doi: 10.1128/AEM.01252-19. Print 2019 Oct 1.

Author Correction: Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart.  Jonathan M Taylor  1 , Carl J Nelson  2 , Finnius A Bruton  3 , Aryan Kaveh  3 , Charlotte Buckley  3 , Carl S Tucker  3 , Adriano G Rossi  4 , John J Mullins  3 , Martin A Denvir.  Nat Commun. 2020 Jul 15;11(1):3648.doi: 10.1038/s41467-020-17483-z.

Functional annotation of human long noncoding RNAs via molecular phenotyping.  Jordan A Ramilowski #  1   2 , Chi Wai Yip #  1   2 , Saumya Agrawal  1   2 , Jen-Chien Chang  1   2 , Yari Ciani  3 , Ivan V Kulakovskiy  4   5 , Mickaël Mendez  6 , Jasmine Li Ching Ooi  2 , John F Ouyang  7 , Nick Parkinson  8 , Andreas Petri et al.  Genome Res. 2020 Jul 27.doi: 10.1101/gr.254219.119. Online ahead of print.

Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database.  Joseph Jacob  1   2 , Daniel Alexander  2 , J Kenneth Baillie  3   4 , Rosalind Berka  5 , Ottavia Bertolli  5 , James Blackwood  6 , Iain Buchan  7 , Claire Bloomfield  8 , Dominic Cushnan et al.  Eur Respir J. 2020 Jul 2;2001809.doi: 10.1183/13993003.01809-2020. Online ahead of print.

Lifespan Extension Via Dietary Restriction: Time to Reconsider the Evolutionary Mechanisms? Joshua P Moatt  1 , Eevi Savola  1 , Jennifer C Regan  2 , Daniel H Nussey  1 , Craig A Walling.  Bioessays. 2020 Jul 8;e1900241.doi: 10.1002/bies.201900241. Online ahead of print.

Expression Profiles of Exosomal MicroRNAs from HEV- and HCV-Infected Blood Donors and Patients: A Pilot Study.  Karen McGowan  1 , Kenneth J Simpson  2 , Juraj Petrik  1.  Viruses. 2020 Jul 30;12(8):E833.doi: 10.3390/v12080833.

The index case of SARS-CoV-2 in Scotland.  Katherine J Hill  1 , Clark D Russell  2 , Sarah Clifford  3 , Kate Templeton  4 , Claire L Mackintosh  3 , Oliver Koch  3 , Rebecca K Sutherland  3.  J Infect. 2020 Jul;81(1):147-178. doi: 10.1016/j.jinf.2020.03.022. Epub 2020 Mar 21.

Can robots help promote testing capacity for SARS-CoV-2?.  Kathrin Cresswell  1 , Sandeep Ramalingam  1 , Aziz Sheikh  1.  J Med Internet Res. 2020 Jul 22.doi: 10.2196/20169. Online ahead of print.

Timelines of infection and transmission dynamics of H1N1pdm09 in swine.  Laetitia Canini  1 , Barbara Holzer  2 , Sophie Morgan  2 , Johanneke Dinie Hemmink  2 , Becky Clark  2 , sLoLa Dynamics Consortium; Mark E J Woolhouse  1 , Elma Tchilian  2 , Bryan Charleston  3.  PLoS Pathog. 2020 Jul 24;16(7):e1008628.doi: 10.1371/journal.ppat.1008628. Online ahead of print.

Prevalence of Disease and Age-Related Behavioural Changes in Cats: Past and Present.  Lorena Sordo  1 , Craig Breheny  1 , Vicky Halls  2 , Amy Cotter  3 , Camilla Tørnqvist-Johnsen  1 , Sarah M A Caney  4 , Danièlle A Gunn-Moore  1.  Vet Sci. 2020 Jul 6;7(3):E85.doi: 10.3390/vetsci7030085.

The Pathogenesis of Fungal-Related Diseases and Allergies in the African Population: The State of the Evidence and Knowledge Gaps.  Lorraine Tsitsi Pfavayi  1   2 , Elopy Nimele Sibanda  3   4   5 , Francisca Mutapi  6   5.  Int Arch Allergy Immunol. 2020;181(4):257-269.doi: 10.1159/000506009. Epub 2020 Feb 18. 

One Health: a multifaceted concept combining diverse approaches to prevent and control antimicrobial resistance.  Luca Guardabassi  1 , Patrick Butaye  2 , David H Dockrell  3 , J Ross Fitzgerald  4 , Ed J Kuijper  5 , ESCMID Study Group for Veterinary Microbiology (ESGVM); ESCMID Study Group for Host and Microbiota Interaction (ESGHAMI).  Clin Microbiol Infect. 2020 Jul 20;S1198-743X(20)30418-3.doi: 10.1016/j.cmi.2020.07.012. Online ahead of print.

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic.  Maciej F Boni  1 , Philippe Lemey  2 , Xiaowei Jiang  3 , Tommy Tsan-Yuk Lam  4 , Blair W Perry  5 , Todd A Castoe  5 , Andrew Rambaut  6 , David L Robertson  7.  Nat Microbiol. 2020 Jul 28. doi: 10.1038/s41564-020-0771-4. Online ahead of print.

Staphylococci among Wild European Rabbits from the Azores: A Potential Zoonotic Issue?  Margarida Sousa  1   2   3   4   5 , Vanessa Silva  4   5   6   7 , Adriana Silva  4   5   6   7 , Nuno Silva  8 , Jessica Ribeiro  4   5   6 , MarÍa Teresa Tejedor-Junco  9 , Rosa Capita et al.  J Food Prot. 2020 Jul 1;83(7):1110-1114.doi: 10.4315/0362-028X.JFP-19-423.

Staphylococcus aureus Lipase 1 Enhances Influenza A Virus Replication.  Mariya I Goncheva  1 , Carina Conceicao  1 , Stephen W Tuffs  1 , Hui-Min Lee  1 , Marlynne Quigg-Nicol  1 , Ian Bennet  1 , Fiona Sargison  1 , Amy C Pickering et al.  mBio. 2020 Jul 7;11(4):e00975-20.doi: 10.1128/mBio.00975-20.

Lessons from Leicester: a covid-19 testing system that's not fit for purpose.  Mike Gill  1 , Devi Sridhar  2 , Fiona Godlee  3.  BMJ. 2020 Jul 7;370:m2690.doi: 10.1136/bmj.m2690.

Molecular detection of 7SL-derived small RNA is a promising alternative for trypanosomosis diagnosis.  Mylène Verney  1 , Finn Grey  2 , Charlène Lemans  1 , Tristan Géraud  1 , David Berthier  3   4 , Sophie Thévenon  3   4 , Alain Rincé  5 , Aymeric Hans  1 , Liam Morrison  2 , Laurent Hébert  1.  Transbound Emerg Dis. 2020 Jul 20. doi: 10.1111/tbed.13744. Online ahead of print.

Erratum: Chakraborty, P. et al. Macrophages from Susceptible and Resistant Chicken Lines have Different Transcriptomes following Marek's Disease Virus Infection. Genes 2019, 10, 74.  Pankaj Chakraborty  1   2 , Richard Kuo  1 , Lonneke Vervelde  1 , Bernadette M Dutia  1 , Pete Kaiser  1 , Jacqueline Smith  1.  Genes (Basel). 2020 Jul 15;11(7):E796.doi: 10.3390/genes11070796

Madin-Darby bovine kidney (MDBK) cells are a suitable cell line for the propagation and study of the bovine poxvirus lumpy skin disease virus.  Petra Fay  1 , Charlotte Cook  1 , Najith Wijesiriwardana  1 , Gessica Tore  1 , Loic Comtet  2 , Alix Carpentier  2 , Barbara Shih  3 , Graham Freimanis  1 , Ismar R Haga  1 , Philippa M Beard  4.  J Virol Methods. 2020 Jul 21;113943. doi: 10.1016/j.jviromet.2020.113943. Online ahead of print.  

Anatomical distribution of respiratory tract leukocyte cell subsets in neonatal calves.  Quinn K Kolar  1 , Lindsey A Waddell  1 , Anna Raper  1 , Mara S Rocchi  2 , Darren J Shaw  1 , Alexander Corbishley  1 , Jayne C Hope  3.  Vet Immunol Immunopathol. 2020 Jul 2;227:110090.doi: 10.1016/j.vetimm.2020.110090. Online ahead of print.

Stability of β-lactam antibiotics in bacterial growth media.  Rebecca Brouwers  1 , Hugh Vass  1 , Angela Dawson  1 , Tracey Squires  1 , Sharareh Tavaddod  1 , Rosalind J Allen  1.  PLoS One. 2020 Jul 20;15(7):e0236198.doi: 10.1371/journal.pone.0236198. eCollection 2020.

IDEAL, the Infectious Diseases of East African Livestock project open access database and biobank.  Rebecca Callaby  1   2 , Cezar Pendarovski  3 , Amy Jennings  4 , Samuel Thumbi Mwangi  5   6 , Ilana Van Wyk  7 , Mary Mbole-Kariuki  8 , Henry Kiara et al.  Sci Data. 2020 Jul 9;7(1):224.doi: 10.1038/s41597-020-0559-7.

Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report.  RECOVERY Collaborative Group; Peter Horby  1 , Wei Shen Lim  1 , Jonathan R Emberson  1 , Marion Mafham  1 , Jennifer L Bell  1 , Louise Linsell  1 , Natalie Staplin  1 , Christopher Brightling  1 , Andrew Ustianowski  1 , Einas Elmahi  1 , Benjamin Prudon  1  et al.  N Engl J Med. 2020 Jul 17.doi: 10.1056/NEJMoa2021436. Online ahead of print. 

COVID-19 in health-care workers in three hospitals in the south of the Netherlands: a cross-sectional study.  Reina S Sikkema  1 , Suzan D Pas  2 , David F Nieuwenhuijse  3 , Áine O'Toole  4 , Jaco Verweij  5 , Anne van der Linden  3 , Irina Chestakova  3 , Claudia Schapendonk  3 , Mark Pronk et al.  Lancet Infect Dis. 2020 Jul 2;S1473-3099(20)30527-2.doi: 10.1016/S1473-3099(20)30527-2. Online ahead of print.

Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct microRNA families and small RNAs that could underpin different functions in the host.  Ruby White  1 , Sujai Kumar  1 , Franklin Wang-Ngai Chow  1 , Elaine Robertson  1 , Kelly S Hayes  2 , Richard K Grencis  2 , María A Duque-Correa  3 , Amy H Buck  4.  Int J Parasitol. 2020 Jul 11;S0020-7519(20)30164-8.doi: 10.1016/j.ijpara.2020.06.002. Online ahead of print. 

Attempts to induce tolerance to Trichostrongylus colubriformis infection in sheep.  Sara S Lundberg  1 , Tom N McNeilly  2 , Robin W McAnulty  1 , Andrew W Greer  1.  Parasite Immunol. 2020 Jul 16;e12776.doi: 10.1111/pim.12776. Online ahead of print.

Temperature Sensitivity: A Potential Method for the Generation of Vaccines against the Avian Coronavirus Infectious Bronchitis Virus.  Sarah Keep  1 , Phoebe Stevenson-Leggett  1 , Angela Steyn  1 , Michael S Oade  1 , Isobel Webb  1 , Jamie Stuart  1 , Lonneke Vervelde  2 , Paul Britton  1 , Helena J Maier  1 , Erica Bickerton  1.  Viruses. 2020 Jul 14;12(7):E754.doi: 10.3390/v12070754.

Quantitative Microdialysis: Experimental Protocol and Software for Small Molecule Protein Affinity Determination and for Exclusion of Compounds with Poor Physicochemical Properties.  Steven Shave  1 , Nhan T Pham  1 , Connor B Śmieja  1 , Manfred Auer  1   2.  Methods Protoc. 2020 Jul 30;3(3):E55. doi: 10.3390/mps3030055.

An Interdisciplinary Working Group to Advocate Universal Palliative Care and Pain Relief Access.  William E Rosa  1 , Mary T White  2   3 , Lacey N Ahern  4   5 , James F Cleary  6 , Liz Grant  7   8 , Keith Martin  9 , Eddie Mwebesa  10 , Christian Ntizimira  11 , Mark Stoltenberg  12 , Nauzley C Abedini  13.  J Palliat Med. 2020 Jul;23(7):882-883.doi: 10.1089/jpm.2020.0085.

Prediction of Colorectal Cancer Risk Based on Profiling with Common Genetic Variants.  Xue Li  1 , Maria Timofeeva  2   3   4 , Athina Spiliopoulou  5 , Paul McKeigue  5 , Yazhou He  1   3 , Xiaomeng Zhang  1 , Victoria Svinti  2   3 , Harry Campbell  1 , Richard S Houlston  6 , Ian Pm Tomlinson  3 , Susan M Farrington  2   3 , Malcolm G Dunlop et al.  Int J Cancer. 2020 Jul 7.doi: 10.1002/ijc.33191. Online ahead of print.

Ceratocystis fimbriata employs a unique infection strategy targeting peltate glandular trichomes of sweetpotato ( Ipomoea batatas) plants.  Yong Sun  1 , Mengqiu Li  2 , Yansu Wang  3 , Lianwei Li  4 , Meng Wang  5 , Xintong Li  6 , Mengke Xu  7 , Gary J Loake  8   9 , Ming Guo  10   11 , Jihong Jiang  12.  Phytopathology. 2020 Jul 20. doi: 10.1094/PHYTO-05-20-0165-R. Online ahead of print.

Global seasonality of human seasonal coronaviruses: a clue for post-pandemic circulating season of SARS-CoV-2 virus?  You Li  1 , Xin Wang  1 , Harish Nair  1   2.  J Infect Dis. 2020 Jul 21;jiaa436.doi: 10.1093/infdis/jiaa436. Online ahead of print.

The immune-related, TGA1 redox-switch: to be or not to be?  Yuan Li  1 , Gary J Loake  1   2.  New Phytol. 2020 Jul 29.doi: 10.1111/nph.16785. Online ahead of print.

June 2020

Surgery for Women With Endometrioma Prior to in vitro Fertilisation: Proposal for a Feasible Multicentre Randomised Clinical Trial in the UK.  Abha Maheshwari  1 , Jemma Healey  2 , Siladitya Bhattacharya  3 , Kevin Cooper  4 , Lucky Saraswat  4 , Andrew W Horne  5 , Jane Daniels  6 , Suzanne Breeman  7 , Kate Brian  8 , Gwenda Burns  9 , Jemma Hudson  10 , Katie Gillies.  Hum Reprod Open. 2020 Jun 6;2020(3):hoaa012.doi: 10.1093/hropen/hoaa012. eCollection 2020.

Re: Effect of progestogen for women with threatened miscarriage: a systematic review and meta-analysis.  Adam J Devall  1 , Ioannis D Gallos  1 , Yakoub Khalaf  2 , Ben Wj Mol  3 , Jackie Ross  4 , Andrew Shennan  2 , Andrew W Horne  5 , Rachel Small et al.  BJOG. 2020 Jun 28.doi: 10.1111/1471-0528.16358. Online ahead of print.

Helminths, Hosts, and Their Microbiota: New Avenues for Managing Gastrointestinal Helminthiases in Ruminants.  Alba Cortés  1   2 , James Rooney  2 , Dave J Bartley  3 , Alasdair J Nisbet  3 , Cinzia Cantacessi.  Expert Rev Anti Infect Ther. 2020 Jun 12.doi: 10.1080/14787210.2020.1782188. Online ahead of print.

Malaria Parasites Regulate Intra-Erythrocytic Development Duration via Serpentine Receptor 10 to Coordinate With Host Rhythms.  Amit K Subudhi  1 , Aidan J O'Donnell  2 , Abhinay Ramaprasad  1 , Hussein M Abkallo  3 , Abhinav Kaushik  1 , Hifzur R Ansari  1 , Alyaa M Abdel-Haleem  1   4 , Fathia Ben Rached et al.  Nat Commun. 2020 Jun 2;11(1):2763. doi: 10.1038/s41467-020-16593-y.

What's the way out? Potential exit strategies from the COVID-19 lockdown.  Aziz Sheikh  1   2 , Asiyah Sheikh  2 , Zakariya Sheikh  2 , Sangeeta Dhami  3 , Devi Sridhar.  J Glob Health. 2020 Jun;10(1):010370.doi: 10.7189/jogh.10.010370.  

Risk factors for Epstein Barr virus-associated cancers: a systematic review, critical appraisal, and mapping of the epidemiological evidence.  Bakkalci D1,2, Jia Y3,2, Winter JR1,2, Lewis JE4, Taylor GS5,6, Stagg HR1,7,6.  J Glob Health. 2020 Jun;10(1):010405. doi: 10.7189/jogh.10.010405.

Rate of Replenishment and Microenvironment Contribute to the Sexually Dimorphic Phenotype and Function of Peritoneal Macrophages.  C C Bain  1 , D A Gibson  2 , N J Steers  3 , K Boufea  4 , P A Louwe  2 , C Doherty  2 , V González-Huici  4 , R Gentek  5 , M Magalhaes-Pinto  6 , T Shaw et al.  Sci Immunol. 2020 Jun 19;5(48):eabc4466. doi: 10.1126/sciimmunol.abc4466.

A Compendium Answering 150 Questions on COVID-19 and SARS-CoV-2.  Carmen Riggioni  1   2 , Pasquale Comberiati  3   4 , Mattia Giovannini  5 , Ioana Agache  6 , Mübeccel Akdis  7 , Magna Alves-Correia  8 , Josep M Antó et al.  Allergy. 2020 Jun 14.doi: 10.1111/all.14449. Online ahead of print.

Development and Validation of an Open Access Snp Array for Nile Tilapia ( Oreochromis niloticus).  Carolina Peñaloza  1 , Diego Robledo  1 , Agustin Barría  1 , Trọng Q Trịnh  2 , Mahirah Mahmuddin  2 , Pamela Wiener  1 , John A H Benzie  3 , Ross D Houston.  G3 (Bethesda). 2020 Jun 12;g3.401343.2020.doi: 10.1534/g3.120.401343. Online ahead of print.

Systems Virology and Human Cytomegalovirus: Using High Throughput Approaches to Identify Novel Host-Virus Interactions During Lytic Infection.  Chen-Hsuin Lee, Finn Grey.  Front Cell Infect Microbiol. 2020 Jun 10;10:280.doi: 10.3389/fcimb.2020.00280. eCollection 2020. 

Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II): protocol for an observational study using linked Scottish national data.  Colin R Simpson  1   2 , Chris Robertson  3   4 , Eleftheria Vasileiou  5 , Jim McMenamin  4 , Rory Gunson  6 , Lewis D Ritchie  7 , Mark Woolhouse  2 , Lynn Morrice et al.  BMJ Open. 2020 Jun 21;10(6):e039097.doi: 10.1136/bmjopen-2020-039097.

The potential for vaccines against scour worms of small ruminants.  Collette Britton  1 , David L Emery  2 , Tom N McNeilly  3 , Alasdair J Nisbet  3 , Michael J Stear.  Int J Parasitol. 2020 Jun 19;S0020-7519(20)30150-8.doi: 10.1016/j.ijpara.2020.04.003. Online ahead of print. 

Minimise, Manage, and Modify: The UK Must Create and Use Time.  Connor Rochford, Devi Sridhar.  Lancet. 2020 Jun 13;395(10240):1829-1830. doi: 10.1016/S0140-6736(20)31055-2. Epub 2020 May 27.

Dissecting the potential role of hepatitis E virus ORF1 nonstructural gene in cross-species infection by using intergenotypic chimeric viruses.  Debin Tian  1 , Danielle M Yugo  1 , Scott P Kenney  2 , C Lynn Heffron  1 , Tanja Opriessnig  3   4 , Anbu K Karuppannan  4 , Jenna Bayne  4 , Patrick G Halbur  4 , Xiang-Jin Meng.  J Med Virol. 2020 Jun 26. doi: 10.1002/jmv.26226. Online ahead of print.

Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump.  Elizabeth M Grimsey  1 , Chiara Fais  2 , Robert L Marshall  1 , Vito Ricci  1 , Maria Laura Ciusa  1 , Jack W Stone  1 , Alasdair Ivens  3 , Giuliano Malloci  2 , Paolo Ruggerone  2 , Attilio V Vargiu  4   5 , Laura J V Piddock.  mBio. 2020 Jun 2;11(3):e00465-20. doi: 10.1128/mBio.00465-20.

Polymersomes Eradicating Intracellular Bacteria.  Federico Fenaroli, James D Robertson, Edoardo Scarpa, Virginia M Gouveia, Claudia Di Guglielmo, Cesare De Pace, Philip M Elks, Alessandro Poma, Dimitrios Evangelopoulos, Julio Ortiz Canseco, Helen M Marriott, David H Dockrell et al.  ACS Nano. 2020 Jun 9.doi: 10.1021/acsnano.0c01870. Online ahead of print. 

Oxygen Provision to Fight COVID-19 in sub-Saharan Africa.  Felix Stein  1   2 , Meghan Perry  3 , Geoffrey Banda  4   5 , Mark Woolhouse  4   2 , Francisca Mutapi.  BMJ Glob Health. 2020 Jun;5(6):e002786.doi: 10.1136/bmjgh-2020-002786.

Assessment of folate and cobalamin concentrations in relation to their dependent intracellular metabolites in serum of pigs between 6 and 26 weeks of age.  Grützner N1, Opriessnig T2, Lopes R3, Suchodolski JS3, Nathues H4, Steiner JM3.  Res Vet Sci. 2020 Jun;130:59-67. doi: 10.1016/j.rvsc.2020.02.002. Epub 2020 Feb 11.

An evidence-based framework for priority clinical research questions for COVID-19.  Harris C1,2, Carson G3,4, Baillie JK4,5, Horby P3,4, Nair H2.  J Glob Health. 2020 Jun;10(1):011001. doi: 10.7189/jogh.10-011001.

EAACI Biologicals Guidelines - Recommendations for Severe Asthma.  Ioana Agache  1 , Cezmi Akdis  2   3 , Mubeccel Akdis  2 , Giorgio Walter Canonica  4 , Thomas Casale  5 , Tomas Chivato  6 , Jonathan Corren  7 , Derek K Chu  8 , Stefano Del Giacco et al.  Allergy. 2020 Jun 2.doi: 10.1111/all.14425. Online ahead of print. 

Detection of Toxoplasma gondii in retail meat samples in Scotland.  Jacqueline Plaza  1 , Filip Dámek  1 , Isabelle Villena  2 , Elisabeth A Innes  1 , Frank Katzer  1 , Clare M Hamilton  1 .  Food Waterborne Parasitol. 2020 Jun 12;20:e00086. doi: 10.1016/j.fawpar.2020.e00086. eCollection 2020 Sep.

ARIA-EAACI statement on Asthma and COVID-19 (June 2, 2020).  Jean Bousquet  1   2   3 , Marek Jutel  4 , Cezmi A Akdis  5 , Ludger Klimek  6 , Oliver Pfaar  7 , Kari C Nadeau  8 , Thomas Eiwegger  9 , Anna Bedbrook  3 , Ignacio J Ansotegui et al.  Allergy. 2020 Jun 26.doi: 10.1111/all.14471. Online ahead of print.

The Dichotomous Responses Driven by β-Defensins.  Jennifer R Shelley  1 , Donald J Davidson  1 , Julia R Dorin.  Front Immunol. 2020 Jun 12;11:1176.doi: 10.3389/fimmu.2020.01176. eCollection 2020.

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins During Infection.  Jessica Sook Yuin Ho  1 , Matthew Angel  2 , Yixuan Ma  1 , Elizabeth Sloan  3 , Guojun Wang  4 , Carles Martinez-Romero  5 , Marta Alenquer  6 , Vladimir Roudko  7 , Liliane Chung et al.  Cell.  2020 Jun 25;181(7):1502-1517.e23. doi: 10.1016/j.cell.2020.05.035. Epub 2020 Jun 18.

Mycobacterium bovis Genomics Reveals Transmission of Infection Between Cattle and Deer in Ireland.  Joseph Crispell  1   2 , Sophie Cassidy  1 , Kevin Kenny  3 , Guy McGrath  4 , Susan Warde  3 , Henrietta Cameron  3 , Gianluigi Rossi  5   6 , Teresa MacWhite  7 , Piran C L White  8 , Samantha Lycett  5 , Rowland R Kao  5   6 , John Moriarty  3 , Stephen V Gordon.  Microb Genom. 2020 Jun 18.doi: 10.1099/mgen.0.000388. Online ahead of print.

Developing Novel Host-Based Therapies Targeting Microbicidal Responses in Macrophages and Neutrophils to Combat Bacterial Antimicrobial Resistance.  Katie Watson  1   2 , Clark D Russell  1   2   3 , J Kenneth Baillie  3 , Kev Dhaliwal  2 , J Ross Fitzgerald  3 , Timothy J Mitchell  4 , A John Simpson  5 , Stephen A Renshaw  6 , David H Dockrell.  Front Immunol. 2020 Jun 5;11:786. doi: 10.3389/fimmu.2020.00786. eCollection 2020.

Effects of the levonorgestrel intrauterine system on the endometrium after long-term exposure to mifepristone: Secondary outcomes of a randomized controlled trial.  Kiriaki Papaikonomou  1 , Caroline Frisendahl  2 , Alistair R W Williams  3 , Kristina Gemzell-Danielsson.  Eur J Obstet Gynecol Reprod Biol. 2020 Jun 26;252:330-335.doi: 10.1016/j.ejogrb.2020.06.056. Online ahead of print.

The disease burden of childhood asthma in China: a systematic review and meta-analysis.  Li X1,2, Song P1,3,2, Zhu Y4, Lei H5, Chan KY1, Campbell H1, Theodoratou E1,6, Rudan I1; Global Health Epidemiology Research Group (GHERG).  J Glob Health. 2020 Jun;10(1):010801. doi: 10.7189/jogh.10.01081.

Molecular Patterns in Acute Pancreatitis Reflect Generalizable Endotypes of the Host Response to Systemic Injury in Humans.  Lucile P A Neyton  1   2 , Xiaozhong Zheng  1 , Christos Skouras  3 , Andrea Doeschl-Wilson  2 , Michael U Gutmann  4 , Iain Uings  5 , Francesco V Rao  6 , Armel Nicolas  6 , Craig Marshall  7 , Lisa-Marie Wilson  7 , J Kenneth Baillie  2 , Damian J Mole.  Ann Surg. 2020 Jun 2.doi: 10.1097/SLA.0000000000003974. Online ahead of print.

Immunology of COVID-19: mechanisms, clinical outcome, diagnostics and perspectives - a report of the European Academy of Allergy and Clinical Immunology (EAACI).  M Sokolowska  1   2 , Z Lukasik  3 , I Agache  4 , C A Akdis  1   2 , D Akdis  5 , M Akdis  1 , W Barcik  6 , H Brough  7   8   9 , T Eiwegger  10   11 , A Eliaszewicz  12 , S Eyerich et al.  Allergy. 2020 Jun 25.doi: 10.1111/all.14462. Online ahead of print.

Determinants and patterns of care-seeking for childhood illness in rural Pune District, India.  Marsh A1,2, Hirve S2, Lele P2, Chavan U2, Bhattacharjee T2,3, Nair H4, Juvekar S2,3,5, Campbell H4,5.  J Glob Health. 2020 Jun;10(1):010601. doi: 10.7189/jogh.10.010601.

Self-management Strategies to Consider to Combat Endometriosis Symptoms During the COVID-19 Pandemic.  Mathew Leonardi  1   2   3 , Andrew W Horne  4 , Katy Vincent  5 , Justin Sinclair  6 , Kerry A Sherman  7 , Donna Ciccia  8 , George Condous  1   2 , Neil P Johnson  9   10   11 , Mike Armour.  Hum Reprod Open. 2020 Jun 1;2020(2):hoaa028. doi: 10.1093/hropen/hoaa028. eCollection 2020.

The Emergence of SARS-CoV-2 in Europe and the US.  Michael Worobey  1 , Jonathan Pekar  2   3 , Brendan B Larsen  1 , Martha I Nelson  4 , Verity Hill  5 , Jeffrey B Joy  6   7   8 , Andrew Rambaut  5 , Marc A Suchard  9   10   11 , Joel O Wertheim  12 , Philippe Lemey.  bioRxiv. 2020 May 23;2020.05.21.109322.doi: 10.1101/2020.05.21.109322. Preprint.

A roadblock-and-kill mechanism of action model for the DNA-targeting antibiotic ciprofloxacin.  Nikola Ojkic  1 , Elin Lilja  1 , Susana Direito  1 , Angela Dawson  1 , Rosalind J Allen  1   2 , Bartlomiej Waclaw.  Antimicrob Agents Chemother. 2020 Jun 29;AAC.02487-19.doi: 10.1128/AAC.02487-19. Online ahead of print.

COVID-19 Pandemic: Practical Considerations on the Organization of an Allergy Clinic - An EAACI/ARIA Position Paper.  O Pfaar  1 , L Klimek  2 , M Jutel  3 , C A Akdis  4 , J Bousquet  5   6   7 , H Breiteneder  8 , S Chinthrajah  9 , Z Diamant  10   11   12 , T Eiwegger  13   14   15 , W J Fokkens  16 , H W Fritsch  17 , K C Nadeau  9 , R E O'Hehir  18   19 , L O'Mahony et al.  Allergy. 2020 Jun 12.doi: 10.1111/all.14453. Online ahead of print.

Influence of the Draining Lymph Nodes and Organized Lymphoid Tissue Microarchitecture on Susceptibility to Intradermal Trypanosoma brucei Infection.  Omar A Alfituri  1 , Barry M Bradford  1 , Edith Paxton  1 , Liam J Morrison  1 , Neil A Mabbott.  Front Immunol. 2020 Jun 3;11:1118.doi: 10.3389/fimmu.2020.01118. eCollection 2020. 

To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host.  Omar A Alfituri  1 , Juan F Quintana  2 , Annette MacLeod  2 , Paul Garside  2 , Robert A Benson  2 , James M Brewer  2 , Neil A Mabbott  1 , Liam J Morrison  1 , Paul Capewell.  Front Immunol. 2020 Jun 12;11:1250.doi: 10.3389/fimmu.2020.01250. eCollection 2020.

Potential Causes of Increased Vocalisation in Elderly Cats with Cognitive Dysfunction Syndrome as Assessed by Their Owners.  Petra Černá  1   2 , Hannah Gardiner  3 , Lorena Sordo  1 , Camilla Tørnqvist-Johnsen  1 , Danièlle A Gunn-Moore.  Animals (Basel). 2020 Jun 24;10(6):E1092.doi: 10.3390/ani10061092.

Comparison of Doppler ultrasonic and oscillometric devices (with or without proprietary optimisations) for non-invasive blood pressure measurement in conscious cats.  Petra Cerna  1   2 , Panos E Archontakis  3 , Hester Ok Cheuk  4 , Danièlle A Gunn-Moore.  J Feline Med Surg. 2020 Jun 25;1098612X20932407.doi: 10.1177/1098612X20932407. Online ahead of print.

Accommodating individual travel history, global mobility, and unsampled diversity in phylogeography: a SARS-CoV-2 case study.  Philippe Lemey, Samuel Hong, Verity Hill, Guy Baele, Chiara Poletto, Vittoria Colizza, Aine O'Toole, John T McCrone, Kristian G Andersen, Michael Worobey, Martha I Nelson, Andrew Rambaut, Marc A Suchard.  bioRxiv. 2020 Jun 23;2020.06.22.165464.doi: 10.1101/2020.06.22.165464. Preprint

Efficacy and safety of single 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis.  Piero L Olliaro  1 , Jean T Coulibaly  2   3   4   5 , Amadou Garba  6 , Christine Halleux  7 , Jennifer Keiser  2   3 , Charles H King  8   9 , Francisca Mutapi  10   11 , Eliézer K N'Goran  4   5 , Giovanna Raso  2   3 , Alexandra U Scherrer  12 , José Carlos Sousa-Figueiredo et al.  PLoS Negl Trop Dis. 2020 Jun 22;14(6):e0008277.doi: 10.1371/journal.pntd.0008277. Online ahead of print.

Reflections on IDEAL: What we have learnt from a unique calf cohort study.  R Callaby  1 , A Jennings  2 , S T Mwangi  3 , M Mbole-Kariuki  4 , I Van Wyk  5 , H Kiara  6 , J A W Coetzer  7 , M E J Woolhouse  8 , O Hanotte  9 , P G Toye  10 , B M deC Bronsvoort.  Prev Vet Med. 2020 Jun 20;181:105062.doi: 10.1016/j.prevetmed.2020.105062. Online ahead of print. 

Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease.  R Kalla  1 , A T Adams  2 , N T Ventham  3 , N A Kennedy  4 , R White  5 , C Clarke  6 , A Ivens  5 , D Bergemalm  7 , S Vatn  8 , B Lopez-Jimena  6 , P Ricanek  8   9 , M H Vatn  9 , J Söderholm  10 , F Gomollón  11 , J K Nowak et al.  J Crohns Colitis. 2020 Jun 29;jjaa134.doi: 10.1093/ecco-jcc/jjaa134. Online ahead of print.

Prevalence and risk factors associated with failure of transfer of passive immunity in spring born beef suckler calves in Great Britain.  Rachel Bragg  1 , Alastair Macrae  2 , Samantha Lycett  3 , Elizabeth Burrough  2 , Geraldine Russell  2 , Alexander Corbishley.  Prev Vet Med. 2020 Jun 13;181:105059.doi: 10.1016/j.prevetmed.2020.105059. Online ahead of print.

Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer.  Rameshkumar Gunasekaran  1 , Prajna Lalitha  1 , Alicia Megia-Fernandez  2 , Mark Bradley  2 , Rachel L Williams  3 , Kevin Dhaliwal  4 , N VenkateshPrajna  5 , Bethany Mills.  Am J Ophthalmol . 2020 Jun 20;S0002-9394(20)30310-X.doi: 10.1016/j.ajo.2020.06.014. Online ahead of print.

Efficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system.  Remi L Gratacap  1 , Tim Regan  2 , Carola E Dehler  3 , Samuel A M Martin  3 , Pierre Boudinot  4 , Bertrand Collet  4 , Ross D Houston.  BMC Biotechnol. 2020 Jun 23;20(1):35.doi: 10.1186/s12896-020-00626-x.

Developments in Marine Invertebrate Primary Culture Reveal Novel Cell Morphologies in the Model Bivalve Crassostrea gigas.  Robert W A Potts  1   2 , Alejandro P Gutierrez  1 , Yennifer Cortés-Araya  1 , Ross D Houston  1 , Tim P Bean.  PeerJ. 2020 Jun 1;8:e9180.doi: 10.7717/peerj.9180. eCollection 2020.

Molecular Dissection of the Antibody Response: Opportunities and Needs for Application in Cattle.  Ruben Barroso  1 , W Ivan Morrison  1 , Liam J Morrison.  Front Immunol. 2020 Jun 12;11:1175.doi: 10.3389/fimmu.2020.01175. eCollection 2020.

Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods.  Samuel H Lewis  1   2   3 , Laura Ross  4 , Stevie A Bain  4 , Eleni Pahita  2   3 , Stephen A Smith  5 , Richard Cordaux  6 , Eric A Miska  1   7 , Boris Lenhard  2   3   8 , Francis M Jiggins  1 , Peter Sarkies.  PLoS Genet. 2020 Jun 25;16(6):e1008864.doi: 10.1371/journal.pgen.1008864. eCollection 2020 Jun.

Limited Cross-Protection against Infectious Bronchitis Provided by Recombinant Infectious Bronchitis Viruses Expressing Heterologous Spike Glycoproteins.  Sarah Keep  1 , Samantha Sives  2 , Phoebe Stevenson-Leggett  1 , Paul Britton  1 , Lonneke Vervelde  2 , Erica Bickerton.  Vaccines (Basel). 2020 Jun 22;8(2):E330.doi: 10.3390/vaccines8020330. 

Defining Immune Correlates During Latent and Active Chlamydial Infection in Sheep.  Sean R Wattegedera  1 , Morag Livingstone  2 , Stephen Maley  2 , Mara Rocchi  2 , Susan Lee  2 , Yvonne Pang  2 , Nick M Wheelhouse  3 , Kevin Aitchison  2 , Javier Palarea-Albaladejo  4 , David Buxton  2 , David Longbottom  2 , Gary Entrican.  Vet Res. 2020 Jun 1;51(1):75. doi: 10.1186/s13567-020-00798-6.

A novel efficient bispecific antibody format, combining a conventional antigen-binding fragment with a single domain antibody, avoids potential heavy-light chain mis-pairing.  Shuyu Huang  1 , Aina Segués  1 , David Lutje Hulsik  2 , Dietmar M Zaiss  3 , Alice J A M Sijts  4 , Sander M J van Duijnhoven  2 , Andrea van Elsas.  J Immunol Methods. 2020 Aug;483:112811.doi: 10.1016/j.jim.2020.112811. Epub 2020 Jun 19.

Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.  Simon Licht-Mayer  1 , Graham R Campbell  1 , Marco Canizares  1 , Arpan R Mehta  1   2 , Angus B Gane  1 , Katie McGill  1 , Aniket Ghosh  1 , Alexander Fullerton  1 , Niels Menezes  1 , Jasmine Dean  1 , Jordon Dunham  3 , Sarah Al-Azki  4 , Gareth Pryce et al.  Acta Neuropathol. 2020 Jun 22.doi: 10.1007/s00401-020-02179-x. Online ahead of print.

Replication of Fifteen Loci Involved in Human Plasma Protein N-glycosylation in 4,802 Samples From Four Cohorts.  Sodbo Zh Sharapov  1 , Alexandra S Shadrina  1 , Yakov A Tsepilov  2   3 , Elizaveta E Elgaeva  1 , Evgeny S Tiys  1 , Sofya G Feoktistova  1 , Olga O Zaytseva  4 , Frano Vuckovic  4 , Rafael Cuadrat  5 , Susanne Jäger  5   6 , Clemens Wittenbecher et al.  Glycobiology. 2020 Jun 10;cwaa053.doi: 10.1093/glycob/cwaa053. Online ahead of print.

Six rounds of annual praziquantel treatment during a national helminth control program significantly reduced schistosome infection and morbidity levels in a cohort of schoolchildren in Zimbabwe .  Takafira Mduluza  1   2 , Caitlin Jones  3   4 , Derick N M Osakunor  3 , Rivka Lim  3   4 , Julius K Kuebel  3   4 , Isaac Phiri  5 , Portia Manangazira  5 , Paradzayi Tagwireyi  6 , Francisca Mutapi.  PLoS Negl Trop Dis. 2020 Jun 22;14(6):e0008388.doi: 10.1371/journal.pntd.0008388. eCollection 2020 Jun.

Update on Possible Animal Sources for COVID-19 in Humans.  Tanja Opriessnig  1   2 , Yao-Wei Huang.  Xenotransplantation. 2020 May;27(3):e12621.doi: 10.1111/xen.12621. Epub 2020 Jun 17.

Porcine Circoviruses: Current Status, Knowledge Gaps and Challenges.  Tanja Opriessnig  1 , Anbu K Karuppannan  2 , Alessandra M M G Castro  3 , Chao-Ting Xiao.  Virus Res. 2020 Jun 2;286:198044. doi: 10.1016/j.virusres.2020.198044. Online ahead of print.

Clinical Morbidity Associated With S. Haematobium Infection in Pre-School Age Children From an Endemic District in Zimbabwe.  Tariro L Mduluza-Jokonya  1   2 , Thajasvarie Naicker  1 , Maritha Kasambala  2 , Luxwell Jokonya  1   3 , Arthur Vengesai  1   3 , Herald Midzi  2 , Emilia Choto  2 , Kempton Musonza  4 , Simba Rusankaniko  4 , Elopy Sibanda  5 , Francisca Mutapi et al. 

Correspondence to "Bronchiolitis Needs a Revisit: Distinguishing Between Virus Entities and Their Treatments".  Tuomas Jartti  1 , Hermelijn H Smits  2 , Klaus Bønnelykke  3 , Ozlem Cavkaytar  4 , Varpu Elenius  1 , Jon R Konradsen  5   6   7 , Heidi Makrinioti  8 , Jakob Stokholm  3 , Gunilla Hedlin  5   6 , Nikolaos Papadopoulos et al.  Allergy. 2020 Jun;75(6):1529-1530.doi: 10.1111/all.14193.

Transcriptome Profiling of Pacu ( Piaractus mesopotamicus) Challenged With Pathogenic Aeromonas hydrophila: Inference on Immune Gene Response.  Vito Antonio Mastrochirico-Filho  1 , Milene Elissa Hata  1 , Rafael Yutaka Kuradomi  1 , Milena Vieira de Freitas  1 , Raquel Belini Ariede  1 , Daniel Guariz Pinheiro  2 , Diego Robledo  3 , Ross Houston  3 , Diogo Teruo Hashimoto.  Front Genet. 2020 Jun 9;11:604.doi: 10.3389/fgene.2020.00604. eCollection 2020.

The UK Veterinary Immunological Toolbox Website: Promoting Vaccine Research by Facilitating Communication and Removing Reagent Barriers.  William Mwangi  1 , Giuseppe Maccari  1   2 , Jayne C Hope  3 , Gary Entrican  3 , John A Hammond.  Immunology. 2020 Jun 16.doi: 10.1111/imm.13227. Online ahead of print.

Predictors of Epstein-Barr virus serostatus and implications for vaccine policy: A systematic review of the literature.  Winter JR1, Jackson C1,2, Lewis JE3,4, Taylor GS5,4, Thomas OG5, Stagg HR1,6.  J Glob Health. 2020 Jun;10(1):010404. doi: 10.7189/jogh.10.010404.

The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis.  You Li  1 , Pallavi Pillai  1 , Fuyu Miyake  1 , Harish Nair.  J Glob Health. 2020 Jun;10(1):010426.doi: 10.7189/jogh.10.010426.

Identification of common deletions in the spike protein of SARS-CoV-2.  Zhe Liu  1   2 , Huanying Zheng  2 , Huifang Lin  1   2 , Mingyue Li  3 , Runyu Yuan  1   2 , Jingju Peng  1   2 , Qianlin Xiong  1   2 , Jiufeng Sun  1   2 , Baisheng Li  2 , Jie Wu  2 , Lina Yi  1   2 , Xiaofang Peng et al.  J Virol. 2020 Jun 22;JVI.00790-20. doi: 10.1128/JVI.00790-20. Online ahead of print.

May 2020

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease.  Aileen Boyle, Chris Plinston, Fraser Laing, Graeme Mackenzie, Robert G Will, Jean C Manson, Abigail B Diack.  Emerg Infect Dis. 2020 Jun;26(6):1300-1303. doi: 10.3201/eid2606.191116.

Feline Aging: Promoting Physiologic and Emotional Well-Being.  Amy Miele , Lorena Sordo , Danielle A Gunn-Moore.  Vet Clin North Am Small Anim Pract. 2020 Jul;50(4):719-748.doi: 10.1016/j.cvsm.2020.03.004.

Validating a GPS-based Approach to Detect Health Facility Visits Against Maternal Response to Prompted Recall Survey.  Andrew Marsh , Siddhivinayak Hirve , Pallavi Lele , Uddhavi Chavan, Tathagata Bhattacharjee , Harish Nair , Harry Campbell  , Sanjay Juvekar.  J Glob Health. 2020 Jun;10(1):010602.doi: 10.7189/jogh.10.010602.

Features of 20 133 UK Patients in Hospital With covid-19 Using the ISARIC WHO Clinical Characterisation Protocol: Prospective Observational Cohort Study.  Annemarie B Docherty, Ewen M Harrison , Christopher A Green, Hayley E Hardwick, Riinu Pius, Lisa Norman, Karl A Holden, Jonathan M Read, et al.  BMJ. 2020 May 22;369:m1985.doi: 10.1136/bmj.m1985. 

High Frequency of Benzimidazole Resistance Alleles in Trichostrongyloids From Austrian Sheep Flocks in an Alpine Transhumance Management System.  Barbara Hinney, Julia Schoiswohl, Lynsey Melville, Vahel J Ameen, Walpurga Wille-Piazzai, Karl Bauer, Anja Joachim, Jürgen Krücken, Philip J Skuce, Reinhild Krametter-Frötscher.  BMC Vet Res. 2020 May 11;16(1):132. doi: 10.1186/s12917-020-02353-z.

Lumpy Skin Disease Is Characterized by Severe Multifocal Dermatitis With Necrotizing Fibrinoid Vasculitis Following Experimental Infection.  Beatriz Sanz-Bernardo, Ismar R Haga, Najith Wijesiriwardana, Philippa C Hawes, Jennifer Simpson, Linda R Morrison, Neil MacIntyre et al.  Vet Pathol. 2020 May;57(3):388-396. doi: 10.1177/0300985820913268.

Outcomes, Microbiology and Antimicrobial Usage in Pressure Ulcer-Related Pelvic Osteomyelitis: Messages for Clinical Practice.  Clark D Russell, Shao-Ting Jerry Tsang, Alasdair Hamish R W Simpson, Rebecca K Sutherland.  J Bone Jt Infect. 2020 Mar 26;5(2):67-75. doi: 10.7150/jbji.41779. eCollection 2020.

Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice.  David S Donaldson, Jolinda Pollock, Prerna Vohra, Mark P Stevens, Neil A Mabbott.  iScience 2020 May 11;23(6):101147. doi: 10.1016/j.isci.2020.101147. Online ahead of print.

Clinical Validation of Full Genotyping CLART® HPV4S Assay on SurePath and ThinPrep Collected Screening Samples According to the International Guidelines for Human Papillomavirus Test Requirements for Cervical Screening.  Ditte Møller Ejegod, Camilla Lagheden, Ramya Bhatia, Helle Pedersen, Elia Alcañiz Boada, Karin Sundström, Javier Cortés, F Xavier Bosch Josë, Kate Cuschieri, Joakim Dillner, Jesper Bonde.  BMC Cancer. 2020 May 6;20(1):396. doi: 10.1186/s12885-020-06888-0.

Canonical Notch Signaling Controls the Early Thymic Epithelial Progenitor Cell State and Emergence of the Medullary Epithelial Lineage in Fetal Thymus Development.  Dong Liu, Anastasia I Kousa, Kathy E O'Neill, Paul Rouse, Martyna Popis, Alison M Farley, Simon R Tomlinson, Svetlana Ulyanchenko, Francois Guillemot, Philip A Seymour, Mette C Jørgensen et al.  Development. 2020 May 28;dev.178582.doi: 10.1242/dev.178582. Online ahead of print.

A Helminth-Derived Suppressor of ST2 Blocks Allergic Responses.  Francesco Vacca, Caroline Chauché, Abhishek Jamwal, Elizabeth C Hinchy, Graham Heieis, Holly Webster, Adefunke Ogunkanbi et al.  Elife. 2020 May 18;9:e54017.doi: 10.7554/eLife.54017.

Cervical Cancer Screening - The Challenges of Complete Pathways of Care in Low-Income Countries: Focus on Malawi.  Heather A Cubie, Christine Campbell.  Womens Health (Lond). Jan-Dec 2020;16:1745506520914804. doi: 10.1177/1745506520914804.

Multi-ancestry GWAS of the Electrocardiographic PR Interval Identifies 202 Loci Underlying Cardiac Conduction.  Ioanna Ntalla, Lu-Chen Weng, James H Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R Tucker, Seung Hoan Choi, Mark D Chaffin et al.  Nat Commun. 2020 May 21;11(1):2542. doi: 10.1038/s41467-020-15706-x.

Hfq CLASH Uncovers sRNA-target Interaction Networks Linked to Nutrient Availability Adaptation.  Ira Alexandra Iosub, Rob Willem van Nues, Stuart William McKellar, Karen Jule Nieken, Marta Marchioretto, Brandon Sy, Jai J Tree, Gabriella Viero, Sander Granneman.  Elife. 2020 May 1;9:e54655. doi: 10.7554/eLife.54655. Online ahead of print.

Importation and Early Local Transmission of COVID-19 in Brazil, 2020.  Jaqueline Goes de Jesus, Claudio Sacchi, Darlan da Silva Candido, Ingra Morales Claro, Flávia Cristina Silva Sales, Erika Regina Manuli et al.  Rev Inst Med Trop Sao Paulo. 2020;62:e30. doi: 10.1590/s1678-9946202062030. Epub 2020 May 11.

The Genetic Architecture of Maternal Effects Across Ontogeny in the Red Deer.  Julie Gauzere, Josephine M Pemberton, Sean Morris, Alison Morris, Loeske E B Kruuk, Craig A Walling.  Evolution. 2020 May 27 doi: 10.1111/evo.14000. Online ahead of print. 

Drive-through Testing in COVID-19: Experience From NHS Lothian.  Katherine Hill, Robyn Campbell, Callum Mutch, Oliver Koch, Claire Mackintosh.  Clin Med (Lond). 2020 May;20(3):290-291. doi: 10.7861/clinmed.2020-0160. Epub 2020 May 1.

Epidemiology and Phylogenetic Analysis of Viral Respiratory Infections in Vietnam.  Lu Lu, Gail Robertson, Jordan Ashworth, Anh Pham Hong, Ting Shi, Alasdair Iven, Guy Thwaites, Stephen Baker, Mark Woolhouse.  Front Microbiol. 2020 May 15;11:833. doi: 10.3389/fmicb.2020.00833. eCollection 2020.

Two Cases of Imported Respiratory Diphtheria in Edinburgh, Scotland, October 2019.  Lucy Li, Daniella Ross, Katherine Hill, Sarah Clifford, Louise Wellington, Colin Sumpter, Naomi J Gadsby, Jennifer Crane, Karen F Macsween, Katie L Hopkins, Norman K Fry, Oliver Koch, Janet Stevenson.  Epidemiol Infect. 2020 May 15;1-11. doi: 10.1017/S0950268820001028. Online ahead of print.

Development of the Gut Microbiota in Early Life: The Impact of Cystic Fibrosis and Antibiotic Treatment.  Maartje Kristensen, Sabine M P J Prevaes, Gino Kalkman, Gerdien A Tramper-Stranders, Raiza Hasrat, Karin M de Winter-de Groot, Hettie M Janssens et al.  J Cyst Fibros. 2020 May 30;S1569-1993(20)30120-X. doi: 10.1016/j.jcf.2020.04.007. Online ahead of print.

Phenotypic Delay in the Evolution of Bacterial Antibiotic Resistance: Mechanistic Models and Their Implications.  Martín Carballo-Pacheco, Michael D Nicholson, Elin E Liljn, Rosalind J Allen, Bartlomiej Waclaw.  PLoS Comput Biol. 2020 May 29;16(5):e1007930. doi: 10.1371/journal.pcbi.1007930. Online ahead of print.

Genomic Analysis of European Drosophila Melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA Viruses.  Martin Kapun, Maite G Barrón, Fabian Staubach, Darren J Obbard, R Axel W Wiberg, Jorge Vieira et al.  Mol Biol Evol . 2020 May 15;msaa120. doi: 10.1093/molbev/msaa120. Online ahead of print.

Important Concepts to Consider in Endometriosis Surgical Trials.  Mathew Leonardi, Andrew W Horne.  BJOG. 2020 May 4. doi: 10.1111/1471-0528.16294. Online ahead of print.

Investigation of a Gamasid Mite Infestation in a UK Textile Mill Caused by Dermanyssus Gallinae (DeGeer, 1778) (Mesostigmata: Dermanyssidae) Special Lineage L1.  N D Sargison, F C Jacinavicius, R H Fleming, U N Chaudhry, L M Costa-Junior.  Parasitol Int. 2020 May 19;102146. doi: 10.1016/j.parint.2020.102146.

Flow Cytometry-Based Assays to Quantify Complement Deposition and Neutrophil Uptake of Group A Streptococcus.  Nicola N Lynskey.  Methods Mol Biol. 2020;2136:233-241. doi: 10.1007/978-1-0716-0467-0_17.

Quality-quantity Trade-Offs Drive Functional Trait Evolution in a Model Microalgal 'Climate Change Winner'.  Rasmus T Lindberg, Sinéad Collins.  Ecol Lett 2020 May;23(5):780-790. doi: 10.1111/ele.13478. Epub 2020 Feb 17.

Protecting Children in Low-Income and Middle-Income Countries From COVID-19.  Salahuddin Ahmed, Tisungane Mvalo, Samuel Akech, Ambrose Agweyu, Kevin Baker, Naor Bar-Zeev, Harry Campbell  et al.   BMJ Glob Health. 2020 May;5(5):e002844.doi: 10.1136/bmjgh-2020-002844.

Hypertonic Saline Nasal Irrigation and Gargling Should Be Considered as a Treatment Option for COVID-19.  Sandeep Ramalingam, Catriona Graham, Jenny Dove, Lynn Morrice, Aziz Sheikh.  J Glob Health. 2020 Jun;10(1):010332. doi: 10.7189/jogh.10.010332.

Monitoring Protein-RNA Interaction Dynamics in Vivo at High Temporal Resolution Using χCRAC.  Stuart W McKellar, Ivayla Ivanova, Robert W van Nues, Ross A Cordiner, Will Worboys, Andrew Langford, Torben Heick Jensen, Sander Granneman.  J Vis Exp. 2020 May 9;(159).doi: 10.3791/61027.

Off the Back Burner: Diverse and Gender-Inclusive Decision-Making for COVID-19 Response and Recovery.  Sulzhan Bali, Roopa Dhatt, Arush Lal, Amina Jama, Kim Van Daalen, Devi Sridhar, Gender and COVID-19 Working Group; Women in Global Health, and Gender and COVID-19 Working Group.  BMJ Glob Health. 2020 May;5(5):e002595. doi: 10.1136/bmjgh-2020-002595.

Predictable Properties of Fitness Landscapes Induced by Adaptational Tradeoffs.  Suman G Das, Susana Ol Direito, Bartek Waclaw, Rosalind J Allen, Joachim Krug.  Elife. 2020 May 19;9:e55155. doi: 10.7554/eLife.55155. Online ahead of print.

Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site.  Umesh Kalathiya, Monikaben Padariya, Marcos Mayordomo, Małgorzata Lisowska, Judith Nicholson, Ashita Singh, Maciej Baginski.  J Clin Med. 2020 May 14;9(5):E1473.doi: 10.3390/jcm9051473.

for statistical Phylogenetics.] Xiang Ji, Zhenyu Zhang, Andrew Holbrook, Akihiko Nishimura, Guy Baele, Andrew Rambaut, Philippe Lemey, Marc A Suchard.   Mol Biol Evol. 2020 May 27;msaa130. doi: 10.1093/molbev/msaa130. Online ahead of print.

Non-genetic Biomarkers and Colorectal Cancer Risk: Umbrella Review and Evidence Triangulation.  Xiaomeng Zhang, Dipender Gill, Yazhou He, Tian Yang,  Xue Li , Grace Monori, Harry Campbell et al.  Cancer Med. 2020 May 12. doi: 10.1002/cam4.3051. Online ahead of print.

Bioelectrical Understanding and Engineering of Cell Biology.  Zoe Schofield, Gabriel N Meloni, Peter Tran, Christian Zerfass, Giovanni Sena, Yoshikatsu Hayashi, Murray Grant et al.  J R Soc Interface. 2020 May;17(166):20200013. doi: 10.1098/rsif.2020.0013. Epub 2020 May 20.

April 2020

Infection With the Sheep Gastrointestinal Nematode Teladorsagia Circumcincta Increases Luminal Pathobionts.  Alba Cortés , John Wills, Xiaopei Su, Rachel E Hewitt, Jack Robertson, Riccardo Scotti, Daniel R G Price, Yvonne Bartley, Tom N McNeilly, Lutz Krause, Jonathan J Powell, Alasdair J Nisbet, Cinzia Cantacessi.  Microbiome. 2020 Apr 30;8(1):60.doi: 10.1186/s40168-020-00818-9.

A Mathematical Model Shows Macrophages Delay Staphylococcus Aureus Replication, but Limitations in Microbicidal Capacity Restrict Bacterial Clearance.  Alex Best, Jamil Jubrail, Mike Boots, David Dockrell, Helen Marriott.  J Theor Biol. 2020 Apr 15;110256. doi: 10.1016/j.jtbi.2020.110256. Online ahead of print.

Neural Imaginaries at Work: Exploring Australian Addiction Treatment Providers' Selective Representations of the Brain in Clinical Practice.  Anthony I Barnett, Martyn Pickersgill, Ella Dilkes-Frayne,  Adrian Carter.  Soc Sci Med. 2020 Apr 7;255:112977. doi: 10.1016/j.socscimed.2020.112977. Online ahead of print.

Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.  Aphasizheva I1, Alfonzo J2, Carnes J3, Cestari I4, Cruz-Reyes J5, Göringer HU et al.  Trends Parasitol. 2020 Apr;36(4):337-355. doi: 10.1016/j.pt.2020.01.006. Epub 2020 Feb 28.

Metagenomic sequencing of clinical samples reveals a single widespread clone of Lawsonia intracellularis responsible for porcine proliferative enteropathy.  Bengtsson RJ1,2, Wee BA3,2, Yebra G2, Bacigalupe R4,2, Watson E5, Guedes RMC6, Jacobson M7, Stadejek T8,9, Archibald AL2, Fitzgerald JR2, Ait-Ali T2.  Microb Genom. 2020 Apr 2. doi: 10.1099/mgen.0.000358. [Epub ahead of print]

Stable isotopes reveal the importance of seabirds and marine foods in the diet of St Kilda field mice.  Bicknell AWJ1,2, Walker BW3, Black T4, Newton J5, Pemberton JM4, Luxmoore R6, Inger R3, Votier SC3.  Sci Rep. 2020 Apr 8;10(1):6088. doi: 10.1038/s41598-020-62672-x.

Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo.  Connelly JC1, Cholewa-Waclaw J1, Webb S1, Steccanella V1, Waclaw B2, Bird A1.  Nucleic Acids Res. 2020 Apr 17;48(7):3542-3552. doi: 10.1093/nar/gkaa102.

Computational design of probes to detect bacterial genomes by multivalent binding.  Curk T1,2,3, Brackley CA3, Farrell JD1, Xing Z4, Joshi D4, Direito S3, Bren U2, Angioletti-Uberti S5, Dobnikar J1,6,7, Eiser E4, Frenkel D6, Allen RJ8.  Proc Natl Acad Sci U S A. 2020 Apr 2. pii: 201918274. doi: 10.1073/pnas.1918274117. [Epub ahead of print]

100 Years of Influenza Research Seen Through the Lens of Covid-19.  Debby Bogaert, David H Dockrell.  Mucosal Immunol. 2020 May 1.doi: 10.1038/s41385-020-0291-9. Online ahead of print.

Modelling the Pandemic.  Devi Sridhar, Maimuna S Majumder.  BMJ. 2020 Apr 21;369:m1567. doi: 10.1136/bmj.m1567.

Rationale and Study Design: A Randomized Controlled Trial of Early Palliative Care in Newly Diagnosed Cancer Patients in Addis Ababa, Ethiopia.  Eleanor Reid, Ephrem Abathun, Jilcha Diribi, Yoseph Mamo, Peter Hall, Marie Fallon, Tigineh Wondemagegnhu, Liz Grant.  Contemp Clin Trials Commun. 2020 Apr 6;18:100564. doi: 10.1016/j.conctc.2020.100564. eCollection 2020 Jun.

Deformability-induced Lift Force in Spiral Microchannels for Cell Separation.  Ewa Guzniczak, Oliver Otto, Graeme Whyte, Nicholas Willoughby, Melanie Jimenez, Helen Bridle.  Lab Chip. 2020 Apr 28. doi: 10.1039/d0lc90036b. Online ahead of print. 

Antigen-presenting ILC3 Regulate T Cell-Dependent IgA Responses to Colonic Mucosal Bacteria.  Felipe Melo-Gonzalez, Hana Kammoun, Elza Evren, Emma E Dutton, Markella Papadopoulou et al.  J Exp Med. 2019 Apr 1;216(4):728-742. doi: 10.1084/jem.20180871. Epub 2019 Feb 27.

Ebola Virus Glycoprotein Stimulates IL-18 Dependent Natural Killer Cell Responses.  Helen R Wagstaffe, Elizabeth A Clutterbuck, Viki Bockstal, Jeroen N Stoop et al.  J Clin Invest. 2020 Apr 21;132438. doi: 10.1172/JCI132438. Online ahead of print.

Regulating the Regulator: Nitric Oxide Control of Post-Translational Modifications.  Jagadis Gupta Kapuganti, Zsuzsanna Kolbert, Jorg Durner, Christian Lindermayr, Francisco J Corpas, Renaud Brouquisse et al.  New Phytol. 2020 Apr 27. doi: 10.1111/nph.16622. Online ahead of print.

Local proliferation of monocytes.  Jenkins SJ1, Knipper JA2, Zaiss DMW2.  J Leukoc Biol. 2020 Apr;107(4):547-549. doi: 10.1002/JLB.1CE0220-534RR. Epub 2020 Feb 28.

Mcl-1 Protects Eosinophils From Apoptosis and Exacerbates Allergic Airway Inflammation.  Jennifer M Felton, David A Dorward, Jennifer A Cartwright, Philippe Md Potey, Calum T Robb, Jingang Gui, Ruth W Craig, Jürgen Schwarze et al.  Thorax. 2020 Apr 17;thoraxjnl-2019-213204.  doi: 10.1136/thoraxjnl-2019-213204. Online ahead of print.

Genomic Epidemiology of SARS-CoV-2 in Guangdong Province, China.  Jing Lu, Louis du Plessis, Zhe Liu, Verity Hill, Min Kang, Huifang Lin, Jiufeng Sun.  Cell . 2020 Apr 28;S0092-8674(20)30486-4. doi: 10.1016/j.cell.2020.04.023. Online ahead of print.

Frugal Filtering Optical Lenses for Point-Of-Care Diagnostics.  Joanna Long, Helen E Parker, Katjana Ehrlich, Michael G Tanner, Kevin Dhaliwal, Bethany Mills.  Biomed Opt Express. 2020 Mar 9;11(4):1864-1875. doi: 10.1364/BOE.381014. eCollection 2020 Apr 1.

Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS: A Controlled Experimental Study in Sheep.  Jonathan E Millar, Nicole Bartnikowski, Margaret R Passmore, Nchafatso G Obonyo et al.  Am J Respir Crit Care Med. 2020 Apr 15. doi: 10.1164/rccm.201911-2143OC. Online ahead of print.

Conservation of Rhodococcus equi (Magnusson 1923) Goodfellow and Alderson 1977 and Rejection of Rhodococcus hoagii (Morse 1912) Kämpfer Et Al. 2014.  José A Vázquez-Boland, Mariela Scortti, Wim G Meijer.  Int J Syst Evol Microbiol. 2020 Apr 24. doi: 10.1099/ijsem.0.004090. Online ahead of print.

The Proximal Origin of SARS-CoV-2.  Kristian G Andersen, Andrew Rambaut, W Ian Lipkin, Edward C Holmes, Robert F Garry.  Nat Med. 2020 Apr;26(4):450-452. doi: 10.1038/s41591-020-0820-9.

FALC Stromal Cells Define a Unique Immunological Niche for the Surveillance of Serous Cavities.  Lucy H Jackson-Jones, Cécile Bénézech.  Curr Opin Immunol. 2020 Apr 27;64:42-49. doi: 10.1016/j.coi.2020.03.008. Online ahead of print.

Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.  Lucy Helen Jackson-Jones, Peter Smith,  Jordan Raymond Portman, Marlène Sophie Magalhaes, Katie Jude Mylonas, Matthieu Marie Vermeren et al.  Immunity 2020 Apr 14;52(4):700-715.e6. doi: 10.1016/j.immuni.2020.03.011.

Handling of Allergen Immunotherapy in the COVID-19 Pandemic: An ARIA-EAACI Statement.  Ludger Klimek, Marek Jutel, Cezmi Akdis, Jean Bousquet, Mübeccel Akdis, Claus Bachert et al.  Allergy. 2020 Apr 24. doi: 10.1111/all.14336. Online ahead of print.

Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine.  Marina Martínez-Álvaro, Marc D Auffret, Robert D Stewart, Richard J Dewhurst, Carol-Anne Duthie et al.  Front Microbiol. 2020 Apr 17;11:659. doi: 10.3389/fmicb.2020.00659. eCollection 2020.

Changed Patterns of Genomic Variation Following Recent Domestication: Selection Sweeps in Farmed Atlantic Salmon.  Marina Naval-Sanchez, Sean McWilliam, Bradley Evans, José M Yáñez,  Ross D Houston, James W Kijas.  Front Genet. 2020 Apr 3;11:264. doi: 10.3389/fgene.2020.00264. eCollection 2020.

Role of Stenotrophomonas maltophilia isolation in patients with non CF bronchiectasis.  Marra R1, Sgalla G2, Richeldi L1, Conte EG3, Hill AT4.  QJM. 2020 Apr 10. pii: hcaa120. doi: 10.1093/qjmed/hcaa120. [Epub ahead of print]

A Competing-Risks Model Explains Hierarchical Spatial Coupling of Measles Epidemics en Route to National Elimination.  Max S Y Lau, Alexander D Becker, Hannah M Korevaar, Quentin Caudron, Darren J Shaw et al.  Nat Ecol Evol . 2020 Apr 27. doi: 10.1038/s41559-020-1186-6. Online ahead of print.

Impact of COVID-19 on Traditional Healthcare Associated Infection Prevention Efforts.  Michael P Stevens, Michelle Doll, Rachel Pryor, Emily Godbout, Kaila Cooper, Gonzalo Bearman.  Infect Control Hosp Epidemiol, 2020 Apr 16;1-6. doi: 10.1017/ice.2020.141. Online ahead of print.

EAACI Research and Outreach Committee: Improving Standards and Facilitating Global Collaboration Through a Research Excellence Network.  Mohamed H Shamji, CezmiA Akdis, Domingo Barber, Walter Canonica, Tomás Chivato, Stefano Del Giacco et al.  Allergy. 2020 Apr 27. doi: 10.1111/all.14340. Online ahead of print.

The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children.  Osakunor DNM1, Munk P2, Mduluza T3, Petersen TN2, Brinch C2, Ivens A4, Chimponda T3, Amanfo SA5,6, Murray J4,6, Woolhouse MEJ5,6, Aarestrup FM2, Mutapi F4,6.  Commun Biol. 2020 Apr 2;3(1):155. doi: 10.1038/s42003-020-0859-7.

Harnessing Genomics to Fast-Track Genetic Improvement in Aquaculture.  Ross D Houston, Tim P Bean, Daniel J Macqueen, Manu Kumar Gundappa, Ye Hwa Jin, Tom L Jenkins  et al.  Nat Rev Genet. 2020 Apr 16. doi: 10.1038/s41576-020-0227-y. Online ahead of print.

A sub-group of patients with hospital-acquired pneumonia do not require broad-spectrum gram-negative antimicrobial coverage.  Russell CD1,2,3, Whittaker E1, Dee DP1, Farquhar E1, Saenz de Villaverde A1, Evans MH2, Laurenson IF3, Mackintosh CL2, Cevik M2,3,4.  Clin Infect Dis. 2020 Apr 8. pii: ciaa391. doi: 10.1093/cid/ciaa391. [Epub ahead of print]

Long-term production effects of clinical cryptosporidiosis in neonatal calves.  Shaw HJ1, Innes EA2, Morrison LJ3, Katzer F2, Wells B4.  Int J Parasitol. 2020 Apr 8. pii: S0020-7519(20)30061-8. doi: 10.1016/j.ijpara.2020.03.002. [Epub ahead of print]

Current perspective on eicosanoids in asthma and allergic diseases - EAACI Task Force consensus report, part I.  Sokolowska M1,2, Rovati GE3, Diamant Z4,5, Untersmayr E6, Schwarze J7, Lukasik Z1, Sava F8, Angelina A9 et al.  Allergy. 2020 Apr 12. doi: 10.1111/all.14295. [Epub ahead of print]

Erysipelothrix Spp.: Past, Present, and Future Directions in Vaccine Research.  Tanja Opriessnig, Taya Forde, Yoshihiro Shimoji.  Front Vet Sci. 2020 Apr 15;7:174. doi: 10.3389/fvets.2020.00174. eCollection 2020.

Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria.  Ucuncu M 1, Mills B , Duncan S , Staderini M , Dhaliwal K , Bradley M .  Chem Commun (Camb). 2020 Apr 4;56(26):3757-3760. doi: 10.1039/d0cc00155d. Epub 2020 Mar 3.

Inflammation-mediated generation and inflammatory potential of human placental cell-free fetal DNA.  van Boeckel SR1, Macpherson H2, Norman JE2, Davidson DJ3, Stock SJ4.  Placenta. 2020 Apr;93:49-55. doi: 10.1016/j.placenta.2020.02.016. Epub 2020 Feb 24.

A novel metabarcoded 18S ribosomal DNA sequencing tool for the detection of Plasmodium species in malaria positive patients.  Wahab A1, Shaukat A2, Ali Q3, Hussain M1, Khan TA1, Khan MAU2, Rashid I4, Saleem MA2, Evans M5, Sargison ND6, Chaudhry U7.  Infect Genet Evol. 2020 Apr 2;82:104305. doi: 10.1016/j.meegid.2020.104305. [Epub ahead of print]

Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study.  Wang X1, Li Y1, O'Brien KL2, Madhi SA3, Widdowson MA4, Byass P5, Omer SB6, Abbas Q7, Ali A7, Amu A8, Azziz-Baumgartner E9, Bassat Q10 et al.  Lancet Glob Health. 2020 Apr;8(4):e497-e510. doi: 10.1016/S2214-109X(19)30545-5. Epub 2020 Feb 20.

A Novel Eukaryote-Like CRISPR Activation Tool in Bacteria: Features and Capabilities.  Yang Liu, Baojun Wang.  Bioessays. 2020 Apr 20;e1900252. doi: 10.1002/bies.201900252. Online ahead of print.

A systematic analysis of interactions between environmental risk factors and genetic variation in susceptibility to colorectal cancer.  Yang T1, Li X2, Farrington SM3, Dunlop MG4, Campbell H2, Timofeeva M3, Theodoratou E5.  Cancer Epidemiol Biomarkers Prev. 2020 Apr 1. pii: cebp.1328.2019. doi: 10.1158/1055-9965.EPI-19-1328. [Epub ahead of print]

Respiratory Syncytial Virus-related Death in Children With Down Syndrome: The RSV GOLD Study.  Yvette N Löwensteyn, Emily W E M Phijffer, Juliette V L Simons, Nienke M Scheltema, Natalie I Mazur, Harish Nair, Louis J Bont, RSV GOLD Study Group.  Pediatr Infect Dis J. 2020 Apr 23. doi: 10.1097/INF.0000000000002666. Online ahead of print.

March 2020

Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines-Recommendations on the use of biologicals in severe asthma.  Agache I1, Song Y2, Rocha C2, Beltran J2, Posso M2,3, Steiner C2, Alonso-Coello P2,4, Akdis C5,6, Akdis M5,6, Canonica GW7, Casale T8, Chivato T9, Corren J10, Del Giacco S11, Eiwegger T12,13,14 et al.  Allergy. 2020 Mar 10. doi: 10.1111/all.14268. [Epub ahead of print]

Horizontal spread of Rhodococcus equi macrolide resistance plasmid pRErm46 across environmental Actinobacteria.  Álvarez-Narváez S1, Giguère S2, Berghaus LJ2, Dailey C3, Vázquez-Boland JA4.  Appl Environ Microbiol. 2020 Mar 13. pii: AEM.00108-20. doi: 10.1128/AEM.00108-20. [Epub ahead of print]

Evidence informing the UK's COVID-19 public health response must be transparent.  Alwan NA1, Bhopal R2, Burgess RA3, Colburn T4, Cuevas LE5, Smith GD6, Egger M6, Eldridge S7, Gallo V8, Gilthorpe MS9, Greenhalgh T10, Griffiths C7, Hunter PR11 et al.  Lancet. 2020 Mar 28;395(10229):1036-1037. doi: 10.1016/S0140-6736(20)30667-X. Epub 2020 Mar 17.

EPIC, Scottish Government's Centre of Expertise in Animal Disease Outbreaks: A Model for Provision of Risk-Based Evidence to Policy.  Boden LA1, Voas S2, Mellor D3, Auty H4.  Front Vet Sci. 2020 Mar 5;7:119. doi: 10.3389/fvets.2020.00119. eCollection 2020. 

Multicenter evaluation of the QIAstat-Dx® Respiratory Panel V2 for the detection of viral and bacterial respiratory pathogens.  Boers SA1, Melchers WJG2, Peters CJA2, Toonen M2, McHugh MP3, Templeton KE3, Claas ECJ4.  J Clin Microbiol. 2020 Mar 30. pii: JCM.01793-19. doi: 10.1128/JCM.01793-19. [Epub ahead of print]

Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: An ARIA-EAACI statement.  Bousquet J1,2,3, Akdis C4, Jutel M5, Bachert C6, Klimek L7, Agache I8, Ansotegui IJ9, Bedbrook A3, Bosnic-Anticevich S10, Canonica GW11,12, Chivato T13, Cruz AA14 et al.  Allergy. 2020 Mar 31. doi: 10.1111/all.14302. [Epub ahead of print]

Research priorities for endometriosis differ among patients, clinicians, and researchers.  Brady PC1, Horne AW2, Saunders PTK3, Thomas AM4, Missmer SA5, Farland LV6.  Am J Obstet Gynecol. 2020 Mar 3. pii: S0002-9378(20)30238-6. doi: 10.1016/j.ajog.2020.02.047. [Epub ahead of print]

Comparative primary paediatric nasal epithelial cell culture differentiation and RSV-induced cytopathogenesis following culture in two commercial media.  Broadbent L1, Manzoor S1, Zarcone MC2, Barabas J1, Shields MD1,3, Saglani S2, Lloyd CM2, Bush A4, Custovic A5, Ghazal P6, Gore M2, Marsland B7, Roberts G8, Schwarze J9, Turner S10, Power UF1.  PLoS One. 2020 Mar 26;15(3):e0228229. doi: 10.1371/journal.pone.0228229. eCollection 2020.

Comprehensive characterisation of transcriptional activity during influenza A virus infection reveals biases in cap-snatching of host RNA sequences.  Clohisey S1,2, Parkinson N1,2, Wang B1,2, Bertin N3, Wise H2,4, Tomoiu A1,2; FANTOM5 Consortium, Summers KM5, Hendry RW1 et al.  J Virol. 2020 Mar 11. pii: JVI.01720-19. doi: 10.1128/JVI.01720-19. [Epub ahead of print]

HYPERVITAMINOSIS D IN A GIANT ANTEATER (MYRMECOPHAGA TRIDACTYLA) AND A LARGE HAIRY ARMADILLO (CHAETOPHRACTUS VILLOSUS) RECEIVING A COMMERCIAL INSECTIVORE DIET.  Cole GC1, Naylor AD2, Hurst E3, Girling SJ2, Mellanby RJ3.  J Zoo Wildl Med. 2020 Mar 17;51(1):245-248. doi: 10.1638/2019-0042.

Rapid fabrication and screening of tailored functional 3D biomaterials.  Conde-González A1, Dutta D1, Wallace R2, Callanan A3, Bradley M4.  Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110489. doi: 10.1016/j.msec.2019.110489. Epub 2019 Nov 27.

In Human Autoimmunity, a Substantial Component of the B Cell Repertoire Consists of Polyclonal, Barely Mutated IgG+ve B Cells.  Cowan GJM1, Miles K2, Capitani L1, Giguere SSB1,3, Johnsson H4, Goodyear C4, McInnes IB4, Breusch S5, Gray D1, Gray M2.  Front Immunol. 2020 Mar 20;11:395. doi: 10.3389/fimmu.2020.00395. eCollection 2020.

Illness-related suffering and need for palliative care in Rohingya refugees and caregivers in Bangladesh: A cross-sectional study.  Doherty M1,2,3, Power L4, Petrova M5, Gunn S6, Powell R7, Coghlan R8, Grant L9, Sutton B10, Khan F11.  PLoS Med. 2020 Mar 3;17(3):e1003011. doi: 10.1371/journal.pmed.1003011. eCollection 2020 Mar.

Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase.  Donaldson DS1, Bradford BM2, Else KJ3, Mabbott NA4.  Sci Rep. 2020 Mar 12;10(1):4554. doi: 10.1038/s41598-020-61483-4.

A core outcome set for future endometriosis research: an international consensus development study.  Duffy J1,2, Hirsch M1,3, Vercoe M4, Abbott J5, Barker C6, Collura B7, Drake R8, Evers J9, Hickey M10, Horne AW11, Hull ML12, Kolekar S8, Lensen S4 et al.  BJOG. 2020 Mar 30. doi: 10.1111/1471-0528.16157. [Epub ahead of print]

Genomic and Immunogenic Protein Diversity of Erysipelothrix rhusiopathiae Isolated From Pigs in Great Britain: Implications for Vaccine Protection.  Forde TL1, Kollanandi Ratheesh N1, Harvey WT1, Thomson JR2, Williamson S3, Biek R1, Opriessnig T4.  Front Microbiol. 2020 Mar 13;11:418. doi: 10.3389/fmicb.2020.00418. eCollection 2020.

USE OF CLINDAMYCIN IN PALLAS' CATS [OTOCOLOBUS (FELIS) MANUL] TO REDUCE JUVENILE TOXOPLASMOSIS-ASSOCIATED MORTALITY RATES.  Girling SJ1, Pizzi R2, Naylor AD2, Richardson D3, Richardson U3, Harley J4, Cole G2, Brown D2, Fraser M5, Tillman E6, Barclay D3.  J Zoo Wildl Med. 2020 Mar 17;51(1):39-45. doi: 10.1638/2018-0206.

Resolution of Inflammation and Gut Repair in IBD: Translational Steps Towards Complete Mucosal Healing.  Ho GT1, Cartwright JA1, Thompson EJ1, Bain CC1, Rossi AG1.  Inflamm Bowel Dis. 2020 Mar 31. pii: izaa045. doi: 10.1093/ibd/izaa045. [Epub ahead of print]

Colostrum provision and care of calves among smallholder farmers in the Kaziranga region of Assam, India.  Hopker A1, Pandey N2, Goswami J2, Hopker S1, Saikia R2, Jennings A1, Saikia D2, Sargison N1, Marsland R3.  PLoS One. 2020 Mar 11;15(3):e0228819. doi: 10.1371/journal.pone.0228819. eCollection 2020.

The benefits of non-invasive ventilation for Community-Acquired Pneumonia: A meta-analysis.  Klefti G1, Hill AT2.  QJM. 2020 Mar 30. pii: hcaa106. doi: 10.1093/qjmed/hcaa106. [Epub ahead of print]

Alternatively activated macrophages promote resolution of necrosis following acute liver injury.  Lewis PS1, Campana L2, Aleksieva N3, Cartwright JA4, Mackinnon A4, O'Duibhir E3, Kendall T5, Vermeren M3, Thomson A6, Gadd V3, Dwyer B3, Aird R3, Man TY3, Rossi AG4, Forrester L3, Park BK7, Forbes SJ8.  J Hepatol. 2020 Mar 10. pii: S0168-8278(20)30133-1. doi: 10.1016/j.jhep.2020.02.031. [Epub ahead of print]

Socio-economic impact of Foot-and-Mouth Disease outbreaks and control measures: An analysis of Mongolian outbreaks in 2017.  Limon G1, Ulziibat G2, Sandag B3, Dorj S2, Purevtseren D2, Khishgee B3, Basan G2, Bandi T3, Ruuragch S2, Bruce M4, Rushton J5, Beard PM1,6, Lyons NA1,7.  Transbound Emerg Dis. 2020 Mar 17. doi: 10.1111/tbed.13547. [Epub ahead of print]

Engineered Recombinant Single Chain Variable Fragment of Monoclonal Antibody Provides Protection to Chickens Infected with H9N2 Avian Influenza.  Lukosaityte D1, Sadeyen JR1, Shrestha A1, Sealy JE1, Bhat S1, Chang P1, Digard P2, Iqbal M1.  Vaccines (Basel). 2020 Mar 3;8(1). pii: E118. doi: 10.3390/vaccines8010118.

A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.  Macleod OJS1, Bart JM2, MacGregor P1, Peacock L3, Savill NJ4, Hester S5, Ravel S2, Sunter JD6, Trevor C1,7, Rust S7, Vaughan TJ7, Minter R7, Mohammed S5, Gibson W3, Taylor MC8, Higgins MK9, Carrington M10.  Nat Commun. 2020 Mar 12;11(1):1326. doi: 10.1038/s41467-020-15125-y.

Infant respiratory syncytial virus prophylaxis and nasopharyngeal microbiota until 6 years of life: a subanalysis of the MAKI randomised controlled trial.  Man WH1, Scheltema NM2, Clerc M3, van Houten MA4, Nibbelke EE2, Achten NB2, Arp K2, Sanders EAM2, Bont LJ2, Bogaert D5.  Lancet Respir Med. 2020 Mar 20. pii: S2213-2600(19)30470-9. doi: 10.1016/S2213-2600(19)30470-9. [Epub ahead of print]

Coronavirus disease (COVID-19) Community Testing Team in Scotland: A 14-day review, 6 to 20 February 2020.  Mark K1, Steel K2, Stevenson J1, Evans C1, McCormick D1, Willocks L1, McCallum A1, Jones L3, Johannessen I4, Templeton K4, Koch O5, Mackintosh C5.  Euro Surveill. 2020 Mar;25(12). doi: 10.2807/1560-7917.ES.2020.25.12.2000217.

Rapid molecular testing for Staphylococcus aureus bacteraemia improves clinical management.  McHugh MP1, Parcell BJ2,3, MacKenzie FM4,3, Templeton KE1, Scottish Microbiology And Virology Network Smvn Molecular Diagnostics Evaluation Group.  J Med Microbiol. 2020 Mar 6. doi: 10.1099/jmm.0.001171. [Epub ahead of print]

Alcelaphine herpesvirus 1 genes A7 and A8 regulate viral spread and are essential for malignant catarrhal fever.  Myster F1, Gong MJ1, Javaux J1, Suárez NM2, Wilkie GS2, Connelley T3, Vanderplasschen A1, Davison AJ2, Dewals BG1.  PLoS Pathog. 2020 Mar 16;16(3):e1008405. doi: 10.1371/journal.ppat.1008405. eCollection 2020 Mar.

Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses.  Purvis HA1, Clarke F1, Montgomery AB1, Colas C1, Bibby JA1, Cornish GH1, Dai X2,3,4, Dudziak D5, Rawlings DJ2,3,4, Zamoyska R6, Guermonprez P1,7, Cope AP1.  Front Immunol. 2020 Mar 4;11:376. doi: 10.3389/fimmu.2020.00376. eCollection 2020.

Characterising the mechanisms underlying genetic resistance to amoebic gill disease in Atlantic salmon using RNA sequencing.  Robledo D1, Hamilton A2,3, Gutiérrez AP4, Bron JE5, Houston RD6.  BMC Genomics. 2020 Mar 30;21(1):271. doi: 10.1186/s12864-020-6694-x.

Bovine viral diarrhoea virus loses quasispecies diversity rapidly in culture.  Russell GC1, Zadoks RN2,1, Willoughby K1, Bachofen C3,1.  Microb Genom. 2020 Mar 11. doi: 10.1099/mgen.0.000343. [Epub ahead of print]

Drosophila as a Model System to Investigate the Effects of Mitochondrial Variation on Innate Immunity.  Salminen TS1,2, Vale PF1.  Front Immunol. 2020 Mar 25;11:521. doi: 10.3389/fimmu.2020.00521. eCollection 2020.

MRSA CC398 recovered from wild boar harboring new SCCmec type IV J3 variant.  Sousa M1, Silva N2, Borges V3, P Gomes J3, Vieira L4, Caniça M5, Torres C6, Igrejas G7, Poeta P8.  J Nematol. 2020;52:1-5. doi: 10.21307/jofnem-2020-025.

Genome sequence of the root-knot nematode Meloidogyne luci.  Susič N1, Koutsovoulos GD2, Riccio C3, Danchin EGJ2, Blaxter ML4, Lunt DH5, Strajnar P1, Širca S1, Urek G1, Stare BG1.  J Nematol. 2020;52:1-5. doi: 10.21307/jofnem-2020-025.

Trends in disease incidence and survival and their effect on mortality in Scotland: nationwide cohort study of linked hospital admission and death records 2001-2016.  Timmers PRHJ1, Kerssens JJ2, Minton J3, Grant I2, Wilson JF4,5, Campbell H4, Fischbacher CM2, Joshi PK4.  BMJ Open. 2020 Mar 25;10(3):e034299. doi: 10.1136/bmjopen-2019-034299.

Characterisation of serum IgG(T) responses to potential diagnostic antigens for equine cyathostominosis.  Tzelos T1, Geyer KK1, Mitchell MC1, McWilliam HEG1, Kharchenko VO2, Burgess STG1, Matthews JB3.  Int J Parasitol. 2020 Mar 12. pii: S0020-7519(20)30038-2. doi: 10.1016/j.ijpara.2020.01.004. [Epub ahead of print].

Microbial evolutionary strategies in a dynamic ocean.  Walworth NG1, Zakem EJ1, Dunne JP2, Collins S3, Levine NM4.  Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5943-5948. doi: 10.1073/pnas.1919332117. Epub 2020 Mar 2.

Comparison of Shiga toxin-encoding bacteriophages in highly pathogenic strains of Shiga toxin-producing Escherichia coli O157:H7 in the UK.  Yara DA1, Greig DR2,3, Gally DL2, Dallman TJ2,3, Jenkins C3.  Microb Genom. 2020 Mar;6(3). doi: 10.1099/mgen.0.000334. Epub 2020 Feb 24.

Cost of Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection Management in Young Children at the Regional and Global Level: A Systematic Review and Meta-Analysis.  Zhang S1, Akmar LZ1, Bailey F1, Rath BA2, Alchikh M2, Schweiger B3, Lucero MG4, Nillos LT4, Kyaw MH5, Kieffer A6, Tong S7, Campbell H1, Beutels P8, Nair H1,9; RESCEU Investigators.  J Infect Dis. 2020 Mar 30. pii: jiz683. doi: 10.1093/infdis/jiz683. [Epub ahead of print]

Low Sensitivity of BinaxNOW RSV in Infants.  Zuurbier RP1,2, Bont LJ1, Langedijk AC1, Hamer M1, Korsten K1, Drysdale SB3, Snape MD3, Robinson H3, Pollard AJ3, Martinón-Torres F4,5, Rodríguez-Tenreiro Sánchez C4 et al.  J Infect Dis. 2020 Mar 30. pii: jiaa050. doi: 10.1093/infdis/jiaa050. [Epub ahead of print]

February 2020

Using sewage for surveillance of antimicrobial resistance.  Aarestrup FM1, Woolhouse MEJ2.  Science. 2020 Feb 7;367(6478):630-632. doi: 10.1126/science.aba3432.

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma.  Agache I1, Beltran J2, Akdis C3, Akdis M3, Canelo-Aybar C2,4, Canonica W5, Casale T6, Chivato T7, Corren J8, Del Giacco S9, Eiwegger T10,11,12 et al.  Allergy. 2020 Feb 8. doi: 10.1111/all.14221. [Epub ahead of print]

Disentangling sRNA-Seq data to study RNA communication between species.  Bermúdez-Barrientos JR1, Ramírez-Sánchez O1, Chow FW2, Buck AH2, Abreu-Goodger C1.  Nucleic Acids Res. 2020 Feb 28;48(4):e21. doi: 10.1093/nar/gkz1198.

Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection.  Casanova V1, Sousa FH1, Shakamuri P2, Svoboda P2, Buch C1, D'Acremont M1, Christophorou MA3, Pohl J2, Stevens C1, Barlow PG1.  Front Immunol. 2020 Feb 4;11:85. doi: 10.3389/fimmu.2020.00085. eCollection 2020.

Beyond Binaries: Dissolving the Empirical/Normative Divide.  Chan S1, Cunningham-Burley S1, de Togni G1, Erikainen S1, Sethi N1, Takashima K2.  AJOB Empir Bioeth. 2020 Jan-Mar;11(1):17-19. doi: 10.1080/23294515.2020.1722290.

Ventilator-associated pneumonia surveillance using two methods.  Craven TH1, Wojcik G2, McCoubrey J3, Brooks O4, Grant E5, Keating S2, Reilly J3, Laurenson IF4, Kefala K6, Walsh TS7.  J Hosp Infect. 2020 Feb 5. pii: S0195-6701(20)30044-X. doi: 10.1016/j.jhin.2020.01.020. [Epub ahead of print]

Physiology of the endometrium and regulation of menstruation.  Critchley HO1, Maybin JA1, Armstrong GM2, Williams ARW1.  Physiol Rev. 2020 Feb 7. doi: 10.1152/physrev.00031.2019. [Epub ahead of print]

SVEPM 2019-Implications of pathogen and antimicrobial evolution on animal health, herd management and policy making, society for veterinary epidemiology and preventive medicine conference Utrecht, the Netherlands 27th-29th March 2019.  Dórea FC1, Vergne T2, Boden L3, Brennan M4, McIntyre KM5.  Prev Vet Med. 2020 Feb 19:104821. doi: 10.1016/j.prevetmed.2019.104821. [Epub ahead of print]

Maternal longevity and offspring sex in wild ungulates.  Douhard M1, Festa-Bianchet M1, Hamel S2, Nussey DH3, Côté SD4, Pemberton JM3, Pelletier F1.  Proc Biol Sci. 2019 Feb 13;286(1896):20181968. doi: 10.1098/rspb.2018.1968.

Online Bayesian phylodynamic inference in BEAST with application to epidemic reconstruction.  Gill MS1, Lemey P1, Suchard MA2,3,4, Rambaut A5,6, Baele G1.  Mol Biol Evol. 2020 Feb 26. pii: msaa047. doi: 10.1093/molbev/msaa047. [Epub ahead of print]

Research priority setting in women's health: A systematic review.  Graham L1, Illingworth BJG2, Showell M3, Vercoe M3, Crosbie EJ4, Gingel LJ5, Farquhar CM3, Horne AW6, Prior M7, Stephenson JM8, Magee LA9, Duffy JMN8,10.  BJOG. 2020 Feb 3. doi: 10.1111/1471-0528.16150. [Epub ahead of print]

Purifying stem cell-derived red blood cells: a high-throughput label-free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration.  Guzniczak E1, Otto O2,3, Whyte G1, Chandra T4, Robertson NA4, Willoughby N1, Jimenez M5, Bridle H1.  Biotechnol Bioeng. 2020 Feb 26. doi: 10.1002/bit.27319. [Epub ahead of print]

A novel technique for retrospective genetic analysis of the response to vaccination or infection using cell-free DNA from archived sheep serum and plasma.  Hanks E1,2, Todd H3, Palarea-Albaladejo J4, McNeilly TN3, Britton C5, Ballingall KT6.  Vet Res. 2020 Feb 5;51(1):9. doi: 10.1186/s13567-020-0737-9.

Understanding HIV-positive drug users' experiences of taking highly active antiretroviral treatment: Identity-Values-Conscious engagement model.  Ho SS1, Stenhouse R1, Holloway A1.  J Clin Nurs. 2020 Feb 25. doi: 10.1111/jocn.15228. [Epub ahead of print]

Identification of Burkholderia pseudomallei Genes Induced During Infection of Macrophages by Differential Fluorescence Induction.   Jitprasutwit S1, Jitprasutwit N1, Hemsley CM2, Onlamoon N3, Withatanung P1, Muangsombut V1, Vattanaviboon P4, Stevens JM5, Ong C6, Stevens MP5, Titball RW2, Korbsrisate S1.  Front Microbiol. 2020 Feb 21;11:72. doi: 10.3389/fmicb.2020.00072. eCollection 2020.

The Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c+ Cells and Colonic Epithelium.  Jones GR1,2,3, Brown SL1,2, Phythian-Adams AT1,2, Ivens AC4, Cook PC1,2, MacDonald AS1,2.  Front Immunol. 2020 Feb 14;11:183. doi: 10.3389/fimmu.2020.00183. eCollection 2020.

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases.  Klarić L1,2, Tsepilov YA3,4, Stanton CM2, Mangino M5,6, Sikka TT7,8, Esko T7,9,10, Pakhomov E3,4, Salo P11, Deelen J12,13, McGurnaghan SJ2, Keser T14 et al.  Sci Adv. 2020 Feb 19;6(8):eaax0301. doi: 10.1126/sciadv.aax0301. eCollection 2020 Feb.

Genomic Prediction Using Low Density Marker Panels in Aquaculture: Performance Across Species, Traits, and Genotyping Platforms.  Kriaridou C1, Tsairidou S1, Houston RD1, Robledo D1.  Front Genet. 2020 Feb 27;11:124. doi: 10.3389/fgene.2020.00124. eCollection 2020.

Quality-quantity trade-offs drive functional trait evolution in a model microalgal 'climate change winner'.  Lindberg RT1, Collins S1.  Ecol Lett. 2020 Feb 17. doi: 10.1111/ele.13478. [Epub ahead of print]

First case report of cutaneous sporotrichosis (Sporothrix species) in a cat in the UK.  Makri N1, Paterson GK2, Gregge F3, Urquhart C4, Nuttall T1.  JFMS Open Rep. 2020 Feb 14;6(1):2055116920906001. doi: 10.1177/2055116920906001. eCollection 2020 Jan-Jun.

Latent tuberculosis infection screening and treatment in congregate settings (TB FREE COREA): protocol for a prospective observational study in Korea.  Min J#1, Kim HW#2, Stagg HR3, Lipman M4,5,6, Rangaka MX7, Myong JP8, Yim HW9, Lim JU10, Lee Y8, Koo HK11, Lee SS11, Park JS12, Cho KS13, Kim JS14.  BMJ Open. 2020 Feb 18;10(2):e034098. doi: 10.1136/bmjopen-2019-034098.

Uptake of Diagnostic Tests by Livestock Farmers: A Stochastic Game Theory Approach.  Mohr S1, Beard R1, Nisbet AJ2, Burgess STG2, Reeve R1, Denwood M3, Porphyre T4, Zadoks RN1,5, Matthews L1.  Mohr S1, Beard R1, Nisbet AJ2, Burgess STG2, Reeve R1, Denwood M3, Porphyre T4, Zadoks RN1,5, Matthews L1.  Front Vet Sci. 2020 Feb 5;7:36. doi: 10.3389/fvets.2020.00036. eCollection 2020.

Antimicrobial host defence peptides: functions and clinical potential.  Mookherjee N1, Anderson MA2, Haagsman HP3, Davidson DJ4.  Nat Rev Drug Discov. 2020 Feb 27. doi: 10.1038/s41573-019-0058-8. [Epub ahead of print]

Natural Killer Cells Dampen the Pathogenic Features of Recall Responses to Influenza Infection.  Mooney JP1,2, Qendro T1, Keith M2, Philbey AW3, Groves HT4, Tregoning JS4, Goodier MR1, Riley EM1,2.  Front Immunol. 2020 Feb 7;11:135. doi: 10.3389/fimmu.2020.00135. eCollection 2020.

Porcine circovirus type 2a or 2b based experimental vaccines provide protection against PCV2d/porcine parvovirus 2 co-challenge.  Opriessnig T1, Karuppannan AK2, Halbur PG2, Calvert JG3, Nitzel GP3, Matzinger SR4, Meng XJ4.  Vaccine. 2020 Feb 18;38(8):1975-1981. doi: 10.1016/j.vaccine.2020.01.013. Epub 2020 Jan 20.

The Pathogenesis of Fungal-Related Diseases and Allergies in the African Population: The State of the Evidence and Knowledge Gaps.  Pfavayi LT1,2, Sibanda EN3,4,5, Mutapi F6,5.  Int Arch Allergy Immunol. 2020 Feb 18:1-13. doi: 10.1159/000506009. [Epub ahead of print]

Resistance to change: AMR gene dynamics on a commercial pig farm with high antimicrobial usage.  Pollock J1,2, Muwonge A2, Hutchings MR1, Mainda G2, Bronsvoort BM2, Gally DL2, Corbishley A3.  Sci Rep. 2020 Feb 3;10(1):1708. doi: 10.1038/s41598-020-58659-3.

Periodic Parasites and Daily Host Rhythms.  Prior KF1, Rijo-Ferreira F2, Assis PA3, Hirako IC4, Weaver DR5, Gazzinelli RT4, Reece SE6.  Cell Host Microbe. 2020 Feb 12;27(2):176-187. doi: 10.1016/j.chom.2020.01.005.

Genetic diversity and multiplicity of infection in Fasciola gigantica isolates of Pakistani livestock.  Rehman ZU1, Zahid O2, Rashid I1, Ali Q3, Akbar MH1, Oneeb M1, Shehzad W4, Ashraf K1, Sargison ND5, Chaudhry U6.  Parasitol Int. 2020 Feb 8:102071. doi: 10.1016/j.parint.2020.102071. [Epub ahead of print]

Porphyromonas gingivalis Sphingolipid Synthesis Limits the Host Inflammatory Response.  Rocha FG1, Moye ZD1, Ottenberg G1, Tang P2, Campopiano DJ2, Gibson FC 3rd1, Davey ME1.  J Dent Res. 2020 Feb 27:22034520908784. doi: 10.1177/0022034520908784. [Epub ahead of print]

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury.  Russell CD1, Millar JE2, Baillie JK3.  Lancet. 2020 Feb 15;395(10223):473-475. doi: 10.1016/S0140-6736(20)30317-2. Epub 2020 Feb 7.

Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals.  Salat J1, Mikulasek K2, Larralde O3, Pokorna Formanova P1, Chrdle A4,5, Haviernik J1,6, Elsterova J1,7,8, Teislerova D4, Palus M1,7, Eyer L1,7, Zdrahal Z2, Petrik J3, Ruzek D1,7.  Vaccines (Basel). 2020 Feb 12;8(1). pii: E81. doi: 10.3390/vaccines8010081.

Models of Osteoarthritis: Relevance and New Insights.  Samvelyan HJ1, Hughes D1, Stevens C1, Staines KA2.  Calcif Tissue Int. 2020 Feb 15. doi: 10.1007/s00223-020-00670-x. [Epub ahead of print]

Acute Cough Due to Acute Bronchitis in Immunocompetent Adult Outpatients: CHEST Expert Panel Report.  Smith MP1, Lown M2, Singh S3, Ireland B4, Hill AT5, Linder JA6, Irwin RS7; CHEST Expert Cough Panel.  Chest. 2020 Feb 21. pii: S0012-3692(20)30329-9. doi: 10.1016/j.chest.2020.01.044. [Epub ahead of print]

Hepatitis E Virus in Pigs from Slaughterhouses, United States, 2017-2019.  Sooryanarain H, Heffron CL, Hill DE, Fredericks J, Rosenthal BM, Werre SR, Opriessnig T, Meng XJ.  Emerg Infect Dis. 2020 Feb;26(2):354-357. doi: 10.3201/eid2602.191348.

The Emerging Role of the c-MET-HGF Axis in Non-small Lung Cancer Tumor Immunology and Immunotherapy.  Titmarsh HF1,2, O'Connor R2, Dhaliwal K2, Akram AR2,3.  Front Oncol. 2020 Feb 6;10:54. doi: 10.3389/fonc.2020.00054. eCollection 2020.

Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom.  Wallace EWJ1, Maufrais C2,3, Sales-Lee J4, Tuck LR1, de Oliveira L2, Feuerbach F5, Moyrand F2, Natarajan P4, Madhani HD4,6, Janbon G2.  Nucleic Acids Res. 2020 Feb 5. pii: gkaa060. doi: 10.1093/nar/gkaa060. [Epub ahead of print]

Harnessing and engineering amide bond forming ligases for the synthesis of amides.  Winn M1, Richardson SM2, Campopiano DJ3, Micklefield J4.  Curr Opin Chem Biol. 2020 Feb 11;55:77-85. doi: 10.1016/j.cbpa.2019.12.004. [Epub ahead of print]

January 2020

A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1).   Abokhrais IM1, Denison FC1, Whitaker LHR1, Saunders PTK2, Doust A1, Williams LJ3, Horne AW1.   PLoS One. 2020 Jan 17;15(1):e0227695. doi: 10.1371/journal.pone.0227695. eCollection 2020.

Avian Pathogenic Escherichia coli (APEC) Strain-Dependent Immunomodulation of Respiratory Granulocytes and Mononuclear Phagocytes in CSF1R-Reporter Transgenic Chickens.  Alber A1, Morris KM1, Bryson KJ1, Sutton KM1, Monson MS2, Chintoan-Uta C1, Borowska D1, Lamont SJ2, Schouler C3, Kaiser P1, Stevens MP1, Vervelde L1.  Front Immunol. 2020 Jan 10;10:3055. doi: 10.3389/fimmu.2019.03055. eCollection 2019.

Assessment of Neutrophil Apoptosis.  Barth ND1, Vendrell M1, Dorward DA1, Rossi AG1, Dransfield I2.  Methods Mol Biol. 2020;2087:167-190. doi: 10.1007/978-1-0716-0154-9_13.

Evidence-based policy: nursing now and the importance of research synthesis.  Benton DC1, Watkins MJ2, Beasley CJ3, Ferguson SL4, Holloway A5.  Int Nurs Rev. 2020 Jan 3. doi: 10.1111/inr.12572. [Epub ahead of print]

Evidence into action: a policy brief exemplar supporting attainment of nursing now.  Benton DC1, Watkins MJ2, Beasley CJ3, Ferguson SL4, Holloway A5.  Int Nurs Rev. 2020 Jan 16. doi: 10.1111/inr.12573. [Epub ahead of print]

Precision cut lung slices: a novel versatile tool to examine host-pathogen interaction in the chicken lung.  Bryson KJ1, Garrido D2, Esposito M3, McLachlan G3, Digard P4, Schouler C2, Guabiraba R5, Trapp S2, Vervelde L4.  Vet Res. 2020 Jan 10;51(1):2. doi: 10.1186/s13567-019-0733-0.

Role of caecal microbiota in the differential resistance of inbred chicken lines to colonization by Campylobacter jejuni.  Chintoan-Uta C1, Wisedchanwet T1, Glendinning L1, Bremner A1, Psifidi A1,2, Vervelde L1, Watson K1, Watson M1, Stevens MP3.  Appl Environ Microbiol. 2020 Jan 24. pii: AEM.02607-19. doi: 10.1128/AEM.02607-19. [Epub ahead of print]

Does respiratory syncytial virus lower respiratory illness in early life cause recurrent wheeze of early childhood and asthma? Critical review of the evidence and guidance for future studies from a World Health Organization-sponsored meeting.  Driscoll AJ1, Arshad SH2, Bont L3, Brunwasser SM4, Cherian T5, Englund JA6, Fell DB7, Hammitt LL8, Hartert TV4, Innis BL9, Karron RA10, Langley GE11, Mulholland EK12, Munywoki PK13, Nair H14 et al.  Vaccine. 2020 Jan 20. pii: S0264-410X(20)30035-9. doi: 10.1016/j.vaccine.2020.01.020. [Epub ahead of print]

Prevalence and characterisation of methicillin-resistant staphylococci from bovine bulk tank milk in England and Wales.  Fisher EA1, Paterson GK2.  J Glob Antimicrob Resist. 2020 Jan 29. pii: S2213-7165(20)30014-X. doi: 10.1016/j.jgar.2020.01.013. [Epub ahead of print]

Deformability-induced lift force in spiral microchannels for cell separation.  Guzniczak E1, Otto O2, Whyte G1, Willoughby N1, Jimenez M3, Bridle H1.  Lab Chip. 2020 Jan 9. doi: 10.1039/c9lc01000a. [Epub ahead of print].

Synthetic Biology Enables Programmable Cell-Based Biosensors.  Hicks M1,2, Bachmann TT3, Wang B1,2.  Chemphyschem. 2020 Jan 16;21(2):131. doi: 10.1002/cphc.201901191.

Endometriosis-Associated Macrophages: Origin, Phenotype, and Function.  Hogg C1, Horne AW1, Greaves E2.  Front Endocrinol (Lausanne). 2020 Jan 23;11:7. doi: 10.3389/fendo.2020.00007. eCollection 2020.

A One Health Approach to Tackle Cryptosporidiosis.  Innes EA1, Chalmers RM2, Wells B3, Pawlowic MC4.  Trends Parasitol. 2020 Jan 23. pii: S1471-4922(20)30009-X. doi: 10.1016/j.pt.2019.12.016. [Epub ahead of print]

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.  Kennedy SA1, Jarboui MA2,3, Srihari S4,5, Raso C1, Bryan K4, Dernayka L2, Charitou T1,4, Bernal-Llinares M4, Herrera-Montavez C1, Krstic A1, Matallanas D1, Kotlyar M6, Jurisica I6,7,8, Curak J9,10,11 et al.  Nat Commun. 2020 Jan 24;11(1):499. doi: 10.1038/s41467-019-14224-9.

The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.  Kitchen GB1,2, Cunningham PS1, Poolman TM3,4, Iqbal M1, Maidstone R3,4, Baxter M3,4, Bagnall J1, Begley N1, Saer B1, Hussell T1, Matthews LC5, Dockrell DH6, Durrington HJ1,2, Gibbs JE1, Blaikley JF7,2, Loudon AS7, Ray DW8,4.  Proc Natl Acad Sci U S A. 2020 Jan 3. pii: 201915932. doi: 10.1073/pnas.1915932117. [Epub ahead of print]

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.  Li B1,2, Clohisey SM3, Chia BS1,2, Wang B3, Cui A2,4, Eisenhaure T2, Schweitzer LD2, Hoover P2, Parkinson NJ3, Nachshon A5, Smith N3 et al.  Nat Commun. 2020 Jan 9;11(1):164. doi: 10.1038/s41467-019-13965-x.

Expression of AraC/XylS stress response regulators in two distinct carbapenem-resistant Enterobacter cloacae ST89 biotypes.  Majewski P1, Gutowska A1, Sacha P1, Schneiders T2, Talalaj M3, Majewska P4, Zebrowska A4, Ojdana D1, Wieczorek P1, Hauschild T5, Kowalczuk O6, Niklinski J6, Radziwon P4,7, Tryniszewska E1.  J Antimicrob Chemother. 2020 Jan 20. pii: dkz569. doi: 10.1093/jac/dkz569. [Epub ahead of print]

Investigation of the in vitro antimicrobial activity of triclosan-coated suture material on bacteria commonly isolated from wounds in dogs.  McCagherty J, Yool DA, Paterson GK, Mitchell SR, Woods S, Marques AI, Hall JL, Mosley JR, Nuttall TJ.  Am J Vet Res. 2020 Jan;81(1):84-90. doi: 10.2460/ajvr.81.1.84.

Reply to Comment from Carl Persson.  McSorley H1, Johansson K2.  Pediatr Allergy Immunol. 2020 Jan 14. doi: 10.1111/pai.13214. [Epub ahead of print]

Surgical treatment of fibroids for subfertility.  Metwally M1, Raybould G2, Cheong YC3, Horne AW4.  Cochrane Database Syst Rev. 2020 Jan 29;1:CD003857. doi: 10.1002/14651858.CD003857.pub4.

Staphylococcal-Produced Bacteriocins and Antimicrobial Peptides: Their Potential as Alternative Treatments for Staphylococcus aureus Infections.  Newstead LL1, Varjonen K2, Nuttall T1, Paterson GK1.  Antibiotics (Basel). 2020 Jan 21;9(2). pii: E40. doi: 10.3390/antibiotics9020040.

A new lineage of segmented RNA viruses infecting animals.  Obbard DJ1, Shi M2, Roberts KE3, Longdon B3, Dennis AB4.  Virus Evol. 2020 Jan 17;6(1):vez061. doi: 10.1093/ve/vez061. eCollection 2020 Jan.

The cost-effectiveness of progesterone in preventing miscarriages in women with early pregnancy bleeding: an economic evaluation based on the PRISM Trial.  Okeke Ogwulu CB1, Goranitis I1,2, Devall AJ3, Cheed V4, Gallos ID3, Middleton LJ4, Harb HM3, Williams HM3, Eapen A5, Daniels JP6, Ahmed A7 et al.  BJOG. 2020 Jan 30. doi: 10.1111/1471-0528.16068. [Epub ahead of print]

Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels.  Paraschiv A1,2, Hegde S3, Ganti R4, Pilizota T3, Šarić A1,2.  Phys Rev Lett. 2020 Jan 31;124(4):048102. doi: 10.1103/PhysRevLett.124.048102.

Low Prevalence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 and mecC MRSA among human isolates in North-West England.  Paterson GK1.  J Appl Microbiol. 2020 Jan 13. doi: 10.1111/jam.14578. [Epub ahead of print]

Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice.  Pavlidis I1, Spiller OB2, Sammut Demarco G3, MacPherson H3, Howie SEM4, Norman JE5, Stock SJ6,7.  Nat Commun. 2020 Jan 10;11(1):199. doi: 10.1038/s41467-019-14089-y.

GLOWORM-PARA: a flexible framework to simulate the population dynamics of the parasitic phase of gastrointestinal nematodes infecting grazing livestock.  Rose Vineer H1, Verschave SH2, Claerebout E3, Vercruysse J3, Shaw DJ4, Charlier J5, Morgan ER6.  Int J Parasitol. 2020 Jan 22. pii: S0020-7519(20)30005-9. doi: 10.1016/j.ijpara.2019.11.005. [Epub ahead of print]

The critical importance of planned small ruminant livestock health and production in addressing global challenges surrounding food production and poverty alleviation.  Sargison ND1.  N Z Vet J. 2020 Jan 22:1-19. doi: 10.1080/00480169.2020.1719373. [Epub ahead of print]

Case report: meningitis as a presenting feature of anti-NMDA receptor encephalitis.  Stavrou M1,2,3, Yeo JM4, Slater AD5, Koch O6, Irani S7, Foley P8,9,10.  BMC Infect Dis. 2020 Jan 7;20(1):21. doi: 10.1186/s12879-020-4761-1.

A Leap Into the Unknown - Early Events in African Trypanosome Transmission.  Szöőr B1, Silvester E2, Matthews KR3.  Trends Parasitol. 2020 Jan 31. pii: S1471-4922(20)30004-0. doi: 10.1016/j.pt.2019.12.011. [Epub ahead of print]

Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response.  Vaughan-Shaw PG1, Zgaga L2, Ooi LY1, Theodoratou E3,4, Timofeeva M1, Svinti V1, Walker M1, O'Sullivan F2, Ewing A1, Johnston S5, Din FVN1, Campbell H3, Farrington SM1, Dunlop MG1.  Gut. 2020 Jan;69(1):103-111. doi: 10.1136/gutjnl-2018-317922. Epub 2019 Apr 25.

Nasopharyngeal microbiota profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections.  Verhagen LM1, Rivera-Olivero IA2,3, Clerc M4, Chu MLJN1, van Engelsdorp Gastelaars J4, Kristensen MI1, Berbers GAM5, Hermans PWM6, de Jonge MI7, de Waard JH2,3, Bogaert D1,4.  Clin Infect Dis. 2020 Jan 10. pii: ciaa015. doi: 10.1093/cid/ciaa015. [Epub ahead of print]

Testing possible causes of gametocyte reduction in temporally out-of-synch malaria infections.  Westwood ML1, O'Donnell AJ2, Schneider P2, Albery GF2,3, Prior KF2, Reece SE2.  Malar J. 2020 Jan 14;19(1):17. doi: 10.1186/s12936-020-3107-1. 

Preparing for the future implementation of respiratory syncytial virus vaccines.  Williams TC1, Kim S2, Spiro DJ3, Campbell H4.  Lancet Respir Med. 2020 Jan 21. pii: S2213-2600(19)30478-3. doi: 10.1016/S2213-2600(19)30478-3. [Epub ahead of print]

Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture.  Zhang Y1,2, Venkateswaran S1, Higuera GA3, Nath S4, Shpak G5,6, Matray J4, Fratila-Apachitei LE4, Zadpoor AA4, Kushner SA4, Bradley M1, De Zeeuw CI3,7.  Adv Healthc Mater. 2020 Jan 15:e1901347. doi: 10.1002/adhm.201901347. [Epub ahead of print]

December 2019

Disentangling sRNA-Seq data to study RNA communication between species.  Bermúdez-Barrientos JR1, Ramírez-Sánchez O1, Chow FW2, Buck AH2, Abreu-Goodger C1.  Nucleic Acids Res. 2019 Dec 27. pii: gkz1198. doi: 10.1093/nar/gkz1198. [Epub ahead of print]

Highly multiplexed quantitative PCR-based platform for evaluation of chicken immune responses.  Borowska D1, Kuo R1, Bailey RA2, Watson KA1,2, Kaiser P1, Vervelde L1, Stevens MP1.  PLoS One. 2019 Dec 3;14(12):e0225658. doi: 10.1371/journal.pone.0225658. eCollection 2019.

Unaltered intravenous prion disease pathogenesis in the temporary absence of marginal zone B cells.  Bradford BM1, Mabbott NA2.  Sci Rep. 2019 Dec 13;9(1):19119. doi: 10.1038/s41598-019-55772-w.

A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial.  Bradley JM1, Anand R2, O'Neill B3, Ferguson K4, Clarke M5, Carroll M6, Chalmers J7, De Soyza A8, Duckers J9, Hill AT10, Loebinger MR11 et al.  Trials. 2019 Dec 19;20(1):747. doi: 10.1186/s13063-019-3766-9.

Small RNAs and extracellular vesicles: New mechanisms of cross-species communication and innovative tools for disease control.  Cai Q1, He B1, Weiberg A2, Buck AH3,4, Jin H1.  PLoS Pathog. 2019 Dec 30;15(12):e1008090. doi: 10.1371/journal.ppat.1008090. eCollection 2019 Dec.

Tackling dementia globally: the Global Dementia Prevention Program (GloDePP) collaboration.  Chan KY1,2, Adeloye D1,3, Asante KP4, Calia C5, Campbell H1, Danso SO6, Juvekar S7, Luz S8, Mohan D9,10, Muniz-Terrera G6, Nitrini R11 et al.  J Glob Health. 2019 Dec;9(2):020103. doi: 10.7189/jogh.09.020103.

Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infections in Children With Bronchopulmonary Dysplasia: Systematic Review and Meta-Analysis.  Chaw PS1, Hua L2, Cunningham S3, Campbell H2, Mikolajczyk R1, Nair H2,4; RESCEU Investigators.  J Infect Dis. 2019 Dec 11. pii: jiz492. doi: 10.1093/infdis/jiz492. [Epub ahead of print]

Elevation of C-reactive protein, P-selectin and Resistin as potential inflammatory biomarkers of urogenital Schistosomiasis exposure in preschool children.  Chimponda TN1, Mushayi C2, Osakunor DNM3, Vengesai A4, Enwono E3, Amanfo S5,6, Murray J3,6, Tshuma C7, Mutapi F3,6, Mduluza T4,6.  BMC Infect Dis. 2019 Dec 19;19(1):1071. doi: 10.1186/s12879-019-4690-z.

Combining genomics and epidemiology to analyse bi-directional transmission of Mycobacterium bovis in a multi-host system.  Crispell J1, Benton CH2, Balaz D3, De Maio N4, Ahkmetova A5, Allen A6, Biek R5, Presho EL6, Dale J7, Hewinson G8, Lycett SJ3, Nunez-Garcia J9, Skuce RA6, Trewby H10, Wilson DJ11, Zadoks RN5, Delahay RJ2, Kao RR3,12.  Elife. 2019 Dec 17;8. pii: e45833. doi: 10.7554/eLife.45833.

Kinetic and structural studies of Trypanosoma and Leishmania phosphofructokinases show evolutionary divergence and identify AMP as a switch regulating glycolysis versus gluconeogenesis.  Fernandes PM1, Kinkead J1, McNae IW1, Vásquez-Valdivieso M1, Wear MA1, Michels PAM1, Walkinshaw MD1.  FEBS J. 2019 Dec 15. doi: 10.1111/febs.15177. [Epub ahead of print]

The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies.  Flanders CA1, Rocke AS1, Edwardson SA2, Baillie JK1, Walsh TS3,4,5.  Crit Care. 2019 Dec 11;23(1):402. doi: 10.1186/s13054-019-2690-4.

Repurposing dichloroacetate for the treatment of women with endometriosis.  Horne AW1, Ahmad SF2, Carter R3, Simitsidellis I4, Greaves E2, Hogg C2, Morton NM3, Saunders PTK4.  Proc Natl Acad Sci U S A. 2019 Dec 2. pii: 201916144. doi: 10.1073/pnas.1916144116. [Epub ahead of print]

Nasal adenocarcinoma associated with jaagsiekte sheep retrovirus infection in a sheep.   Jahns H1,2, Cousens C1,2.  J Vet Diagn Invest. 2019 Dec 30:1040638719897032. doi: 10.1177/1040638719897032. [Epub ahead of print]

Population Structure and Genetic Diversity of Nile Tilapia (Oreochromis niloticus) Strains Cultured in Tanzania.  Kajungiro RA1,2, Palaiokostas C1, Pinto FAL1, Mmochi AJ3, Mtolera M3, Houston RD4, de Koning DJ1.  Front Genet. 2019 Dec 20;10:1269. doi: 10.3389/fgene.2019.01269. eCollection 2019.

Development and implementation of a nurse-led allergy clinic model in primary care: feasibility trial protocol.  Kelman M1, Hammersley V2, Kendall M1, Mukherjee M1, Morrice L1, Harley S1, Schwarze J1,3, Sheikh A1.  NPJ Prim Care Respir Med. 2019 Dec 6;29(1):44. doi: 10.1038/s41533-019-0155-5.

Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen.  Knipper JA1,2, Ivens A1,2, Taylor MD1,2.  PLoS Negl Trop Dis. 2019 Dec 9;13(12):e0007908. doi: 10.1371/journal.pntd.0007908. [Epub ahead of print]

Immunoglobulin A deficiency in children, an undervalued clinical issue.  Koenen MHM1, van Montfrans JMJ2, Sanders EAME3, Bogaert DD4, Verhagen LML5.  Clin Immunol. 2019 Dec;209:108293. doi: 10.1016/j.clim.2019.108293. Epub 2019 Oct 31.

Why colorectal screening fails to achieve the uptake rates of breast and cervical cancer screening: a comparative qualitative study.  Kotzur M1, McCowan C2, Macdonald S1, Wyke S1, Gatting L1, Campbell C3, Weller D4, Crighton E5, Steele RJC6, Robb KA7.  BMJ Qual Saf. 2019 Dec 26. pii: bmjqs-2019-009998. doi: 10.1136/bmjqs-2019-009998. [Epub ahead of print]

Development and evaluation of a quantitative polymerase chain reaction for aquatic Streptococcus agalactiae based on the groEL gene.  Leigh WJ1,2, Zadoks RN1,2, Costa JZ1, Jaglarz A1, Thompson KD1.  J Appl Microbiol. 2019 Dec 18. doi: 10.1111/jam.14556. [Epub ahead of print]

Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania.  Malaria Genomic Epidemiology Network.  Nat Commun. 2019 Dec 16;10(1):5732. doi: 10.1038/s41467-019-13480-z. 

Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo.  Mendoza-Ochoa GI1, Barrass JD1, Maudlin IE1, Beggs JD1.  RNA Biol. 2019 Dec;16(12):1775-1784. doi: 10.1080/15476286.2019.1657788. Epub 2019 Sep 4.

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.  Montazeri Z1, Li X2, Nyiraneza C1, Ma X3, Timofeeva M4, Svinti V4, Meng X2, He Y2, Bo Y5, Morgan S1, Castellví-Bel S6, Ruiz-Ponte C7, Fernández-Rozadilla C7 et al.  Gut. 2019 Dec 9. pii: gutjnl-2019-319313. doi: 10.1136/gutjnl-2019-319313. [Epub ahead of print]

Azathioprine Has a Deleterious Effect on the Bone Health of Mice with DSS-Induced Inflammatory Bowel Disease.  Morgan S1, Hooper KM1,2, Milne EM3, Farquharson C3, Stevens C1, Staines KA1.  Int J Mol Sci. 2019 Dec 3;20(23). pii: E6085. doi: 10.3390/ijms20236085.

A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya.  Muloi D1,2,3,4, Fèvre EM5,3,4, Bettridge J5,3, Rono R3, Ong'are D3, Hassell JM5,3, Karani MK3, Muinde P3, van Bunnik B1,2, Street A6, Chase-Topping M2,7, Pedersen AB8, Ward MJ2,9, Woolhouse M1,2.  J Glob Health. 2019 Dec;9(2):010412. doi: 10.7189/jogh.09.020412.

Maximising and evaluating the uptake, use and impact of golf and health studies.  Murray A1,2, Kelly P3, Morton S4, Glover D5, Duncan J2, Hawkes R6,7, Grant L8, Mutrie N9.  Br J Sports Med. 2019 Dec 19. pii: bjsports-2019-100994. doi: 10.1136/bjsports-2019-100994. [Epub ahead of print]

Hypoxia Modulates Platelet Purinergic Signalling Pathways.  Paterson GG1,2, Young JM1,2, Willson JA3, Graham CJ1,2, Dru RC1,2, Lee EW1,2, Torpey GS1,2, Walmsley SR3, Chan MV4, Warner TD4, Baillie JK1,5,6, Thompson AAR1,7.  Thromb Haemost. 2019 Dec 13. doi: 10.1055/s-0039-3400305. [Epub ahead of print]

Genomic epidemiology of methicillin-resistant Staphylococcus sciuri carrying a SCCmec-mecC hybrid element.  Paterson GK1.  Infect Genet Evol. 2019 Dec 17;79:104148. doi: 10.1016/j.meegid.2019.104148. [Epub ahead of print]

Cervids as sentinel-species for tick-borne encephalitis virus in Norway - A serological study.  Paulsen KM1,2, das Neves CG3, Granquist EG2, Madslien K3, Stuen S4, Pedersen BN1,5, Vikse R1, Rocchi M6, Laming E6, Stiasny K7, Andreassen ÅK1.  Zoonoses Public Health. 2019 Dec 19. doi: 10.1111/zph.12675. [Epub ahead of print]

Drug Target Selection for Trypanosoma cruzi Metabolism by Metabolic Control Analysis and Kinetic Modeling.  Saavedra E1, González-Chávez Z1, Moreno-Sánchez R1, Michels PAM2.  Curr Med Chem. 2019;26(36):6652-6671. doi: 10.2174/0929867325666180917104242.

The UK's Global Health Respiratory Network: Improving respiratory health of the world's poorest through research collaborations.  Sheikh A1,2, Campbell H1,2, Balharry D1,2, Adab P3,4, Barreto ML5, Bauld L1,6, Cooper P7,8, Cruz A9,8, Davidson FM1,6, Dodd P10, Enocson A3,4 et al.  J Glob Health. 2019 Dec;9(2):020104. doi: 10.7189/jogh.09.020104.

IMPACT study on intervening with a manualised package to achieve treatment adherence in people with tuberculosis: protocol paper for a mixed-methods study, including a pilot randomised controlled trial.  Stagg HR1, Abubakar I2, Campbell CN3, Copas A4, Darvell M3, Horne R5, Kielmann K6, Kunst H7, Mandelbaum M8, Pickett E9, Story A10, Vidal N6, Wurie FB2, Lipman M11,9.  BMJ Open. 2019 Dec 17;9(12):e032760. doi: 10.1136/bmjopen-2019-032760.

Temporal Factors and Missed Doses of Tuberculosis Treatment: A Causal Associations Approach to Analyses of Digital Adherence Data.  Stagg HR1, Lewis JJ2, Liu X3, Huan S4, Jiang S3, Chin DP4, Fielding KL5.  Ann Am Thorac Soc. 2019 Dec 20. doi: 10.1513/AnnalsATS.201905-394OC. [Epub ahead of print]

Optimizing Low-Cost Genotyping and Imputation Strategies for Genomic Selection in Atlantic Salmon.  Tsairidou S1, Hamilton A2, Robledo D3, Bron JE4, Houston RD3.  G3 (Bethesda). 2019 Dec 11. pii: g3.400800.2019. doi: 10.1534/g3.119.400800. [Epub ahead of print] 

Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes.  Ucar A1, González-Fernández E2, Staderini M2, Avlonitis N2, Murray AF1, Bradley M2, Mount AR2.  Analyst. 2019 Dec 12. doi: 10.1039/c9an02321f. [Epub ahead of print]

Antibody-Dependent Natural Killer Cell Activation after Ebola Vaccination.  Wagstaffe HR1,2, Clutterbuck EA3, Bockstal V4, Stoop JN4, Luhn K4, Douoguih M4, Shukarev G4, Snape MD3, Pollard AJ3, Riley EM1,5, Goodier MR1. J Infect Dis. 2019 Dec 10. pii: jiz657. doi: 10.1093/infdis/jiz657. [Epub ahead of print]

Comparison of Escherichia coli surface attachment methods for single-cell microscopy.  Wang YK1, Krasnopeeva E2, Lin SY1, Bai F3, Pilizota T4, Lo CJ5. Sci Rep. 2019 Dec 19;9(1):19418. doi: 10.1038/s41598-019-55798-0.

Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system.  Wu Z1, Harne R1, Chintoan-Uta C1, Hu TJ1, Wallace R2, MacCallum A1, Stevens MP1, Kaiser P1, Balic A3, Hume DA4.  Dev Comp Immunol. 2019 Dec 20;105:103586. doi: 10.1016/j.dci.2019.103586. [Epub ahead of print]

Novel circovirus species identified in farmed pigs designated as Porcine circovirus 4, Hunan province, China.  Zhang HH1, Hu WQ1, Li JY1, Liu TN1, Opriessnig T2, Zhou JY3, Xiao CT1.  Transbound Emerg Dis. 2019 Dec 10. doi: 10.1111/tbed.13446. [Epub ahead of print]

November 2019

Differences in immune responses to Haemonchus contortus infection in the susceptible Ile de France and the resistant Santa Ines sheep under different anthelmintic treatments regimens.  Albuquerque ACA1, Bassetto CC2, Almeida FA2, Hildersley KA3,4, McNeilly TN4, Britton C3, Amarante AFT2.  Vet Res. 2019 Nov 29;50(1):104. doi: 10.1186/s13567-019-0722-3.

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.  Allen RJ1, Guillen-Guio B2, Oldham JM3, Ma SF4, Dressen A5, Paynton ML1, Kraven LM1, Obeidat M6, Li X7 et al.  Am J Respir Crit Care Med. 2019 Nov 11. doi: 10.1164/rccm.201905-1017OC. [Epub ahead of print]

The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY.  Armstrong JF1, Faccenda E1, Harding SD1, Pawson AJ1, Southan C1, Sharman JL1, Campo B2, Cavanagh DR3, Alexander SPH4, Davenport AP5, Spedding M6, Davies JA1; NC-IUPHAR.  Nucleic Acids Res. 2019 Nov 6. pii: gkz951. doi: 10.1093/nar/gkz951. [Epub ahead of print]

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension.  Arnold ND1, Pickworth JA1, West LE1, Dawson S1, Carvalho JA2, Casbolt H1, Braithwaite AT1, Iremonger J1, Renshall L1, Germaschewski V2 et al.  Nat Commun. 2019 Nov 15;10(1):5183. doi: 10.1038/s41467-019-13139-9.

Correction to: The rumen microbiome as a reservoir of antimicrobial resistance and pathogenicity genes is directly affected by diet in beef cattle.  Auffret MD1, Dewhurst RJ2, Duthie CA2, Rooke JA2, Wallace RJ3, Freeman TC4, Stewart R5, Watson M4,5, Roehe R2.  Microbiome. 2019 Nov 18;7(1):149. doi: 10.1186/s40168-019-0764-9.

The Risk of Foot and Mouth Disease Transmission Posed by Public Access to the Countryside During an Outbreak.  Auty H1, Mellor D2, Gunn G1, Boden LA3.  Front Vet Sci. 2019 Nov 5;6:381. doi: 10.3389/fvets.2019.00381. eCollection 2019.

Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep.  Banos G1,2,3, Clark EL2, Bush SJ2,4, Dutta P2, Bramis G3, Arsenos G3, Hume DA2,5, Psifidi A2,6.  PLoS One. 2019 Nov 25;14(11):e0214346. doi: 10.1371/journal.pone.0214346. eCollection 2019.

The role of selection and evolution in changing parturition date in a red deer population.  Bonnet T1, Morrissey MB2, Morris A3, Morris S3, Clutton-Brock TH4, Pemberton JM3, Kruuk LEB1.  PLoS Biol. 2019 Nov 5;17(11):e3000493. doi: 10.1371/journal.pbio.3000493. eCollection 2019 Nov.

Tissue tropism and transmission ecology predict virulence of human RNA viruses.  Brierley L1, Pedersen AB1, Woolhouse MEJ1.  PLoS Biol. 2019 Nov 26;17(11):e3000206. doi: 10.1371/journal.pbio.3000206. eCollection 2019 Nov.

Chronic pelvic pain in women: an embedded qualitative study to evaluate the perceived benefits of the meridian balance method electro-acupuncture treatment, health consultation and National Health Service standard care.  Chong OT1,2,3, Critchley HO1, Horne AW1, Fallon M2, Haraldsdottir E4.  Br J Pain. 2019 Nov;13(4):244-255. doi: 10.1177/2049463718814870. Epub 2018 Nov 21.

Use of the rSpaA415 antigen indicates low rates of Erysipelothrix rhusiopathiae infection in farmed cattle from the United States of America and Great Britain.  Cubas Atienzar AI1, Gerber PF2, Opriessnig T3,4.  BMC Vet Res. 2019 Nov 1;15(1):388. doi: 10.1186/s12917-019-2147-7.

Child car seat safety advice: a public health concern.  Dale HL1, Pickersgill MD2.  J Public Health (Oxf). 2019 Nov 28. pii: fdz144. doi: 10.1093/pubmed/fdz144. [Epub ahead of print].

Habitat and host factors associated with liver fluke (Fasciola hepatica) diagnoses in wild red deer (Cervus elaphus) in the Scottish Highlands.  French AS1,2, Zadoks RN3,4,5, Skuce PJ4, Mitchell G4, Gordon-Gibbs DK4, Taggart MA6.  Parasit Vectors. 2019 Nov 12;12(1):535. doi: 10.1186/s13071-019-3782-3.

HIV-1 accessory protein Vpr interacts with REAF/RPRD2 to mitigate its antiviral activity.  Gibbons JM1, Marno KM1, Pike R1, Lee WJ1, Jones CE1, Ogunkolade BW1, Pardieu C1, Bryan A2, Fu RM2, Warnes G1, Rowley PA3, Sloan RD2,4, McKnight Á5.  J Virol. 2019 Nov 27. pii: JVI.01591-19. doi: 10.1128/JVI.01591-19. [Epub ahead of print]

Differentiation and adaptation of natural killer cells for anti-malarial immunity.  Goodier MR1, Wolf AS1,2, Riley EM1,3.  Immunol Rev. 2019 Nov 24. doi: 10.1111/imr.12798. [Epub ahead of print]

International survey confirms that women with endometriosis-associated pain experience a high prevalence of pain imagery and coping imagery.  Graham CJ1, Brown SL2, Vincent K3, Horne AW4.  Eur J Obstet Gynecol Reprod Biol. 2019 Nov 10. pii: S0301-2115(19)30486-5. doi: 10.1016/j.ejogrb.2019.10.030. [Epub ahead of print]

Terminal investment strategies following infection are dependent on diet.  Hudson AL1, Moatt JP1, Vale PF1.  J Evol Biol. 2019 Nov 9. doi: 10.1111/jeb.13566. [Epub ahead of print]

A vaccinology Approach to the Identification and Characterization of Dermanyssus Gallinae Candidate Protective Antigens for the Control of Poultry Red Mite Infestations.  Lima-Barbero JF1,2, Contreras M1, Mateos-Hernández L3, Mata-Lorenzo FM1, Triguero-Ocaña R1, Sparagano O4 et al.  Vaccines (Basel). 2019 Nov 20;7(4). pii: E190. doi: 10.3390/vaccines7040190.

A guide to machine learning for bacterial host attribution using genome sequence data.  Lupolova N1, Lycett SJ1, Gally DL1.  Microb Genom. 2019 Nov 28. doi: 10.1099/mgen.0.000317. [Epub ahead of print]

Quantifying Mycobacterium avium subspecies paratuberculosis infection of bovine monocyte derived macrophages by confocal microscopy.  Mathie HA1, Jensen K2, Stevens JM2, Glass EJ2, Hope JC2.  J Microbiol Methods. 2019 Nov 19:105779. doi: 10.1016/j.mimet.2019.105779. [Epub ahead of print]

Africa should set its own health-research agenda.  Mutapi F.  Nature. 2019 Nov;575(7784):567. doi: 10.1038/d41586-019-03627-9.

Social Media in Nursing and Health Policy: A Commentary.  O'Connor S1, Holloway A1.  Policy Polit Nurs Pract. 2019 Nov 7:1527154419886292. doi: 10.1177/1527154419886292. [Epub ahead of print]

Challenging social structures and changing research cultures.  Pickersgill M1, Cunningham-Burley S2, Engelmann L2, Ganguli-Mitra A2, Hewer R2, Young I2.  Lancet. 2019 Nov 9;394(10210):1693-1695. doi: 10.1016/S0140-6736(19)32635-2.

Uncertainty work as ontological negotiation: adjudicating access to therapy in clinical psychology.  Pickersgill M1.  Sociol Health Illn. 2019 Nov 26. doi: 10.1111/1467-9566.13029. [Epub ahead of print]

Ancient introgression between two ape malaria parasite species.  Plenderleith LJ1, Liu W2, Learn GH2, Loy DE2,3, Speede S4, Sanz CM5,6, Morgan DB6,7, Bertolani P8, Hart JA9, Hart TB9, Hahn BH2,3, Sharp PM1.  Genome Biol Evol. 2019 Nov 7. pii: evz244. doi: 10.1093/gbe/evz244. [Epub ahead of print]

Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo.  Quintana JF1, Kumar S1, Ivens A1, Chow FWN1, Hoy AM1, Fulton A1, Dickinson P1, Martin C2, Taylor M1, Babayan SA3, Buck AH1.  PLoS Negl Trop Dis. 2019 Nov 26;13(11):e0007811. doi: 10.1371/journal.pntd.0007811. [Epub ahead of print]

Rectal swabs are a reliable proxy for faecal samples in infant gut microbiota research based on 16S-rRNA sequencing.  Reyman M1,2, van Houten MA2, Arp K1, Sanders EAM1,3, Bogaert D4,5.  Sci Rep. 2019 Nov 5;9(1):16072. doi: 10.1038/s41598-019-52549-z.

Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life.  Reyman M1,2, van Houten MA2, van Baarle D3, Bosch AATM1, Man WH1,2, Chu MLJN1, Arp K1, Watson RL4, Sanders EAM1,3, Fuentes S3, Bogaert D5,6.  Nat Commun. 2019 Nov 25;10(1):5352. doi: 10.1038/s41467-019-13373-1.

The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries).  Sparks AM1,2, Watt K1, Sinclair R1, Pilkington JG1, Pemberton JM1, McNeilly TN3, Nussey DH1, Johnston SE1.  PLoS Genet. 2019 Nov 7;15(11):e1008461. doi: 10.1371/journal.pgen.1008461. [Epub ahead of print]

Back to the future? Health and the World Bank's human capital index.  Stein F1, Sridhar D1.  BMJ. 2019 Nov 13;367:l5706. doi: 10.1136/bmj.l5706.

Adaptive prospective optical gating enables day-long 3D time-lapse imaging of the beating embryonic zebrafish heart.   Taylor JM1, Nelson CJ2, Bruton FA3, Baghbadrani AK3, Buckley C3, Tucker CS3, Rossi AG4, Mullins JJ3, Denvir MA3.  Nat Commun. 2019 Nov 15;10(1):5173. doi: 10.1038/s41467-019-13112-6.

Seasonal influenza vaccine effectiveness in people with asthma: a national test-negative design case-control study.  Vasileiou E, Sheikh A1, Butler CC2, Robertson C3, Kavanagh K4, Englishby T4, Lone NI1, von Wissmann B5, McMenamin J5, Ritchie LD6, Schwarze J7, Gunson R8, Simpson CR9.  Clin Infect Dis. 2019 Nov 5. pii: ciz1086. doi: 10.1093/cid/ciz1086. [Epub ahead of print]

Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle.  Vohra P1, Vrettou C2, Hope JC2, Hopkins J2, Stevens MP2.  Vet Res. 2019 Nov 27;50(1):99. doi: 10.1186/s13567-019-0720-5. 

ILF3 contributes to the establishment of the antiviral type I interferon program.  Watson SF1, Bellora N2, Macias S1.  Nucleic Acids Res. 2019 Nov 8. pii: gkz1060. doi: 10.1093/nar/gkz1060. [Epub ahead of print]

Predictors of Epstein-Barr virus serostatus in young people in England.  Winter JR1, Taylor GS2, Thomas OG2, Jackson C1,3, Lewis JEA4, Stagg HR5,6.  BMC Infect Dis. 2019 Nov 28;19(1):1007. doi: 10.1186/s12879-019-4578-y.

October 2019

Does urbanization make emergence of zoonosis more likely? Evidence, myths and gaps.  Ahmed S, Dávila JD, Allen A, Haklay MM, Tacoli C, Fèvre EM.  Environ Urban. 2019 Oct;31(2):443-460. doi: 10.1177/0956247819866124. Epub 2019 Sep 14.

NNAlign_MA; MHC peptidome deconvolution for accurate MHC binding motif characterization and improved T cell epitope predictions.  Alvarez B1, Reynisson B2, Barra C1, Buus S3, Ternette N4, Connelley T5, Andreatta M6, Nielsen M7,2.  Mol Cell Proteomics. 2019 Oct 2. pii: mcp.TIR119.001658. doi: 10.1074/mcp.TIR119.001658. [Epub ahead of print]

Clonal Confinement of a Highly Mobile Resistance Element Driven by Combination Therapy in Rhodococcus equi.  Álvarez-Narváez S1, Giguère S2, Anastasi E1, Hearn J3, Scortti M1, Vázquez-Boland JA4.  MBio. 2019 Oct 15;10(5). pii: e02260-19. doi: 10.1128/mBio.02260-19.

The behavior of dairy cattle in late gestation: Effects of parity and dystocia.  Barraclough RAC1, Shaw DJ2, Boyce R3, Haskell MJ4, Macrae AI5.  J Dairy Sci. 2019 Oct 16. pii: S0022-0302(19)30912-9. doi: 10.3168/jds.2019-16500. [Epub ahead of print]

Cell mediated and innate immune responses in pigs following vaccination and challenge with Toxoplasma parasites.  Bartley PM1, Burrells A2, Benavides J3, Canton G4, Garcia JL5, Thomson J2, Chianini F2, Innes EA2, Katzer F2.  Vet Parasitol. 2019 Oct 17;275:108963. doi: 10.1016/j.vetpar.2019.108963. [Epub ahead of print]

A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression.  Burgess STG1, Marr EJ2, Bartley K2, Nunn FG2, Down RE3, Weaver RJ3, Prickett JC3, Dunn J3, Rombauts S4,5,6, Van Leeuwen T7, Van de Peer Y4,5,6,8, Nisbet AJ2.  BMC Genomics. 2019 Oct 23;20(1):756. doi: 10.1186/s12864-019-6082-6.

Acute Lower Respiratory Infections Associated With Respiratory Syncytial Virus in Children With Underlying Congenital Heart Disease: Systematic Review and Meta-analysis.  Chaw PS1, Wong SWL2, Cunningham S3, Campbell H2, Mikolajczyk R1, Nair H2,4; RESCEU Investigators.  J Infect Dis. 2019 Oct 10. pii: jiz150. doi: 10.1093/infdis/jiz150. [Epub ahead of print]

Associations of autozygosity with a broad range of human phenotypes. Clark DW1, Okada Y2,3,4, Moore KHS5, Mason D6, Pirastu N1, Gandin I7,8, Mattsson H9,10, Barnes CLK1, Lin K11, Zhao JH12,13, Deelen P14, Rohde R15, Schurmann C16, Guo X17 et al.  Nat Commun. 2019 Oct 31;10(1):4957. doi: 10.1038/s41467-019-12283-6.

A role for palliative care in advancing health in conflict settings.  Coghlan R1, Leng M2, Shamieh O3, Elessi K4, Grant L2.  Lancet. 2019 Oct 12;394(10206):1324. doi: 10.1016/S0140-6736(19)31826-4.

Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei.  Cooper S1, Wadsworth ES1, Ochsenreiter T2, Ivens A1, Savill NJ1, Schnaufer A1.  Nucleic Acids Res. 2019 Oct 30. pii: gkz928. doi: 10.1093/nar/gkz928. [Epub ahead of print].

Comparison of molecular assays for HPV testing in oropharyngeal squamous cell carcinomas: a population-based study in Northern Ireland.  Craig SG1, Anderson LA2, Moran M3, Graham L4, Currie K1, Rooney K5, Robinson M6, Bingham V7, Cuschieri KS8, McQuaid S7, Schache AG9, Jones TM10, McCance D11, Salto-Tellez M4, McDade SS4, James JA12.  Cancer Epidemiol Biomarkers Prev. 2019 Oct 30. pii: cebp.0538.2019. doi: 10.1158/1055-9965.EPI-19-0538. [Epub ahead of print]

Phenotypic and genetic analysis of milk and serum element concentrations in dairy cows.  Denholm SJ1, Sneddon AA2, McNeilly TN3, Bashir S2, Mitchell MC3, Wall E4.  J Dairy Sci. 2019 Oct 3. pii: S0022-0302(19)30867-7. doi: 10.3168/jds.2019-16960. [Epub ahead of print]

Shiga toxin sub-type 2a increases the efficiency of Escherichia coli O157 transmission between animals and restricts epithelial regeneration in bovine enteroids.  Fitzgerald SF1,2, Beckett AE1,2, Palarea-Albaladejo J3, McAteer S1, Shaaban S1, Morgan J1,2, Ahmad NI4, Young R1, Mabbott NA1, Morrison L1, Bono JL5, Gally DL1, McNeilly TN2.  PLoS Pathog. 2019 Oct 3;15(10):e1008003. doi: 10.1371/journal.ppat.1008003. eCollection 2019 Oct.

Challenges in the diagnosis of paediatric pneumonia in intervention field trials: recommendations from a pneumonia field trial working group.  Goodman D1, Crocker ME2, Pervaiz F1, McCollum ED3, Steenland K4, Simkovich SM1, Miele CH1, Hammitt LL5, Herrera P1, Zar HJ6, Campbell H7,  Lancet Respir Med. 2019 Oct 4. pii: S2213-2600(19)30249-8. doi: 10.1016/S2213-2600(19)30249-8. [Epub ahead of print]

Antiviral activity of the mineralocorticoid receptor NR3C2 against Herpes simplex virus Type 1 (HSV-1) infection.  Haas JG1, Weber J1, Gonzalez O2, Zimmer R2, Griffiths SJ3.  Sci Rep. 2018 Oct 26;8(1):15876. doi: 10.1038/s41598-018-34241-w.

Cumulative weather effects can impact across the whole life cycle.  Hindle BJ1,2, Pilkington JG3, Pemberton JM3, Childs DZ1.  Glob Chang Biol. 2019 Oct;25(10):3282-3293. doi: 10.1111/gcb.14742. Epub 2019 Jul 25.

What do HIV-positive drug users' experience tell us about their antiretroviral medications taking? An international integrated literature review.  Ho IS1, Holloway A1, Stenhouse R1.  Addiction. 2019 Oct 18. doi: 10.1111/add.14857. [Epub ahead of print]

Global selective sweep of a highly inbred genome of the cattle parasite Neospora caninum.  Khan A1, Fujita AW1, Randle N2, Regidor-Cerrillo J3, Shaik JS1, Shen K4, Oler AJ4, Quinones M4, Latham SM5, Akanmori BD6, Cleaveland S7, Innes EA8 et al.  Proc Natl Acad Sci U S A. 2019 Oct 21. pii: 201913531. doi: 10.1073/pnas.1913531116. [Epub ahead of print]

The PHYTOGLOBIN-NO Cycle Regulates Plant Mycorrhizal Symbiosis.  Kumari A1, Pathak PK1, Loake GJ2, Gupta KJ3.  Trends Plant Sci. 2019 Oct 14. pii: S1360-1385(19)30244-4. doi: 10.1016/j.tplants.2019.09.007. [Epub ahead of print]

Asparagine Deprivation Causes a Reversible Inhibition of Human Cytomegalovirus Acute Virus Replication.  Lee CH1, Griffiths S2, Digard P1, Pham N3, Auer M3, Haas J2, Grey F4.  MBio. 2019 Oct 8;10(5). pii: e01651-19. doi: 10.1128/mBio.01651-19.

Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.  Li X1, Meng X1, He Y1, Spiliopoulou A2, Timofeeva M3, Wei WQ4, Gifford A4, Yang T1, Varley T5, Tzoulaki I6,7, Joshi P1, Denny JC4, Mckeigue P2, Campbell H1, Theodoratou E1,8.  PLoS Med. 2019 Oct 18;16(10):e1002937. doi: 10.1371/journal.pmed.1002937. eCollection 2019 Oct.

Developmental competence and antigen switch frequency can be uncoupled in Trypanosoma brucei.  McWilliam KR1,2,3, Ivens A1, Morrison LJ4, Mugnier MR5, Matthews KR6.  Proc Natl Acad Sci U S A. 2019 Oct 21. pii: 201912711. doi: 10.1073/pnas.1912711116. [Epub ahead of print]

A simulation study of aggregation mediated by production of cohesive molecules.  Melaugh G1, Marenduzzo D1, Morozov A1, Allen RJ1.  Soft Matter. 2019 Oct 31. doi: 10.1039/c9sm01462d. [Epub ahead of print]

How are arbovirus vectors able to tolerate infection?  Oliveira JH1, Bahia AC2, Vale PF3.  Dev Comp Immunol. 2019 Oct 1;103:103514. doi: 10.1016/j.dci.2019.103514. [Epub ahead of print]

Bacillus pumilus probiotic feed supplementation mitigates Lawsonia intracellularis shedding and lesions.  Opriessnig T1,2, Karuppannan AK3, Beckler D4, Ait-Ali T5, Cubas-Atienzar A5, Halbur PG3.  Vet Res. 2019 Oct 22;50(1):85. doi: 10.1186/s13567-019-0696-1.

Approaches to use the WHO respiratory syncytial virus surveillance platform to estimate disease burden.  Pebody R1, Moyes J2, Hirve S3, Campbell H4, Jackson S3, Moen A3, Nair H4, Simões EAF5, Smith PG6, Wairagkar N7, Zhang W3.  Influenza Other Respir Viruses. 2019 Oct 8. doi: 10.1111/irv.12667. [Epub ahead of print]

Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand.  Proto WR1, Siegel SV1, Dankwa S2, Liu W3,4, Kemp A1, Marsden S1, Zenonos ZA1, Unwin S5,6, Sharp PM7, Wright GJ1, Hahn BH3,4, Duraisingh MT2, Rayner JC8,9.  Nat Commun. 2019 Oct 4;10(1):4512. doi: 10.1038/s41467-019-12294-3.

Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation.  Rahman A1, Henry KM1, Herman KD1, Thompson AAR1, Isles HM1, Tulotta C1, Sammut D1, Rougeot JJ2, Khoshaein N1, Reese AE1, Higgins K1, Tabor C3, Sabroe I1 et al.  Elife. 2019 Oct 15;8. pii: e50990. doi: 10.7554/eLife.50990. [Epub ahead of print]

Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1.  Skelly MJ1, Furniss JJ1, Grey HL1, Wong KW1, Spoel SH1.  Elife. 2019 Oct 7;8. pii: e47005. doi: 10.7554/eLife.47005. [Epub ahead of print]

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.  Tin A1,2, Marten J3, Halperin Kuhns VL4, Li Y5, Wuttke M5, Kirsten H6,7, Sieber KB8, Qiu C9, Gorski M10,11, Yu Z12,13, Giri A14,15, Sveinbjornsson G16 et al.  Nat Genet. 2019 Oct 2. doi: 10.1038/s41588-019-0504-x. [Epub ahead of print]

A survey of the level of horse owner uptake of evidence-based anthelmintic treatment protocols for equine helminth control in the UK.  Tzelos T1, Morgan ER2, Easton S3, Hodgkinson JE4, Matthews JB3.  Vet Parasitol. 2019 Oct;274:108926. doi: 10.1016/j.vetpar.2019.108926. Epub 2019 Sep 19.

Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease.  Veluchamy A1, Ballerini L2,3, Vitart V4, Schraut KE5,6, Kirin M5,7, Campbell H5, Joshi PK5, Relan D3,8, Harris S9,10,11, Brown E12 et al.  Arterioscler Thromb Vasc Biol. 2019 Oct 10:ATVBAHA119312552. doi: 10.1161/ATVBAHA.119.312552. [Epub ahead of print]

Synthetic Biology Enables Programmable Cell-Based Biosensors.  Wang B1, Hicks M2, Bachmann TT3.  Chemphyschem. 2019 Oct 4. doi: 10.1002/cphc.201900739. [Epub ahead of print]

Cryptosporidium Prevalence in Calves and Geese Co-Grazing on Four Livestock Farms Surrounding Two Reservoirs Supplying Public Water to Mainland Orkney, Scotland.  Wells B1, Paton C2, Bacchetti R3, Shaw H4, Stewart W5, Plowman J6, Katzer F7, Innes EA8.  Microorganisms. 2019 Oct 30;7(11). pii: E513. doi: 10.3390/microorganisms7110513.

September 2019

Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex.  Abad MA1, Ruppert JG#1, Buzuk L#1, Wear M1, Zou J1, Webb KM1, Kelly DA1, Voigt P1, Rappsilber J1,2, Earnshaw WC1, Jeyaprakash AA3.  J Cell Biol. 2019 Sep 30. pii: jcb.201905040. doi: 10.1083/jcb.201905040. [Epub ahead of print]

Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.  Balogun EO#1,2, Inaoka DK#2,3,4, Shiba T#5, Tsuge C2, May B6, Sato T7, Kido Y1,8, Nara T9, Aoki T9, Honma T7, Tanaka A7, Inoue M10 et al. FASEB J. 2019 Sep 16:fj201901342R. doi: 10.1096/fj.201901342R. [Epub ahead of print]

Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine-An Emerging Strategy.  Birch GP1,2, Campbell T2, Bradley M1, Dhaliwal K2.  Front Oncol. 2019 Sep 12;9:882. doi: 10.3389/fonc.2019.00882. eCollection 2019.

On measuring selection in cancer from subclonal mutation frequencies.  Bozic I1, Paterson C1, Waclaw B2.  PLoS Comput Biol. 2019 Sep 26;15(9):e1007368. doi: 10.1371/journal.pcbi.1007368. eCollection 2019 Sep.

Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression.  Bradford BM1, Wijaya CAW1, Mabbott NA1.  Front Cell Neurosci. 2019 Sep 10;13:411. doi: 10.3389/fncel.2019.00411. eCollection 2019.

A pyruvate dehydrogenase complex disorder hypothesis for bipolar disorder.  Campbell I1, Campbell H2.  Med Hypotheses. 2019 Sep;130:109263. doi: 10.1016/j.mehy.2019.109263. Epub 2019 Jun 8.

Characterization of CD79αcy+ cells in placentas from ruminants.  Cantón GJ1, Schock A2, Melo de Sousa N3, Beckers JF3, Chianini F4.  Vet Immunol Immunopathol. 2019 Sep 13;217:109942. doi: 10.1016/j.vetimm.2019.109942. [Epub ahead of print]

Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+CD8+ T, CD8+ T, and γδ T cell responses.  Cao QM1, Tian D1, Heffron CL1, Subramaniam S1, Opriessnig T2, Foss DL3, Calvert JG3, Meng XJ4. Virology. 2019 Sep 17;538:35-44. doi: 10.1016/j.virol.2019.09.006. [Epub ahead of print]

Host susceptibility to severe influenza A virus infection.  Clohisey S1, Baillie JK2,3.  Crit Care. 2019 Sep 5;23(1):303. doi: 10.1186/s13054-019-2566-7.

Infection by the castrating parasitic nematode Sphaerularia bombi changes gene expression in Bombus terrestris bumblebee queens.  Colgan TJ1,2,3, Carolan JC4, Sumner S5, Blaxter ML6, Brown MJF7.  Insect Mol Biol. 2019 Sep 30. doi: 10.1111/imb.12618. [Epub ahead of print]

Endometriosis and Risk of Adverse Pregnancy Outcomes.  Farland LV1, Prescott J, Sasamoto N, Tobias DK, Gaskins AJ, Stuart JJ, Carusi DA, Chavarro JE, Horne AW, Rich-Edwards JW, Missmer SA.  Obstet Gynecol. 2019 Sep;134(3):527-536. doi: 10.1097/AOG.0000000000003410.

Senescence in immunity against helminth parasites predicts adult mortality in a wild mammal.  Froy H1,2, Sparks AM3,4, Watt K3, Sinclair R3, Bach F5, Pilkington JG3, Pemberton JM3, McNeilly TN6, Nussey DH3.  Science. 2019 Sep 20;365(6459):1296-1298. doi: 10.1126/science.aaw5822.

Emerging Species and Genome Editing Tools: Future Prospects in Cyanobacterial Synthetic Biology.  Gale GAR1,2,3, Schiavon Osorio AA4,5, Mills LA6, Wang B7,8, Lea-Smith DJ9, McCormick AJ10,11.  Microorganisms. 2019 Sep 29;7(10). pii: E409. doi: 10.3390/microorganisms7100409.

The genetic landscape of Scotland and the Isles.  Gilbert E1,2, O'Reilly S3, Merrigan M3, McGettigan D3, Vitart V4, Joshi PK5, Clark DW5, Campbell H5, Hayward C4, Ring SM6,7, Golding J8 et al.  Proc Natl Acad Sci U S A. 2019 Sep 3. pii: 201904761. doi: 10.1073/pnas.1904761116. [Epub ahead of print]

Intrusive imagery associated with pain.  Graham CJ1, Brown SL2, Vincent K3, Horne AW4.  BMJ. 2019 Sep 10;366:l5459. doi: 10.1136/bmj.l5459.

Implication of human papillomavirus (HPV) infection in the paediatric population.  Guerendiain D1, Healy K2, Johannessen I3,4, Cuschieri K3.  BMJ Sex Reprod Health. 2019 Sep 4. pii: bmjsrh-2018-200175. doi: 10.1136/bmjsrh-2018-200175. [Epub ahead of print]

A comprehensive study of the effect on colorectal cancer survival of common germline genetic variation previously linked with cancer prognosis.  He Y1, Timofeeva M2, Li X3, Din FV1, Blackmur JP4, Vaughan-Shaw P4, Svinti V4, Farrington SM2, Campbell H3, Dunlop MG5, Theodoratou E6.  Cancer Epidemiol Biomarkers Prev. 2019 Sep 5. pii: cebp.0596.2019. doi: 10.1158/1055-9965.EPI-19-0596. [Epub ahead of print]

Evaluating the population impact of hepatitis C direct acting antiviral treatment as prevention for people who inject drugs (EPIToPe) - a natural experiment (protocol).  Hickman M1, Dillon JF2, Elliott L3, De Angelis D4, Vickerman P5, Foster G6,7, Donnan P8, Eriksen A9, Flowers P3, Goldberg D3,10 et al.  BMJ Open. 2019 Sep 24;9(9):e029538. doi: 10.1136/bmjopen-2019-029538.

Interleukin 10 knock-down in bovine monocyte-derived macrophages has distinct effects during infection with two divergent strains of Mycobacterium bovis.  Jensen K1, Stevens JM1, Glass EJ1.  PLoS One. 2019 Sep 17;14(9):e0222437. doi: 10.1371/journal.pone.0222437. eCollection 2019.

Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions.  Johnston H1, Dickinson P2, Ivens A2, Buck AH2, Levine RD3, Remacle F4, Campbell CJ5.  Proc Natl Acad Sci U S A. 2019 Sep 10. pii: 201909455. doi: 10.1073/pnas.1909455116. [Epub ahead of print]

Recommendations on terminology and experimental best practice associated with plant nitric oxide research.  Kapuganti JG1, Hancock JT2, Petrivalsky M3, Kolbert Z4, Lindermayr C5, Durner J5, Barroso JB6, Palma JM7, Brouquisse R8, Wendehenne D9, Corpas FJ7, Loake GJ10.  New Phytol. 2019 Sep 3. doi: 10.1111/nph.16157. [Epub ahead of print]

A forty year journey: The generation and roles of NO in plants.  Kolbert Z1, Barroso JB2, Brouquisse R3, Corpas FJ4, Gupta KJ5, Lindermayr C6, Loake GJ7, Palma JM4, Petřivalský M8, Wendehenne D9, Hancock JT10.  Nitric Oxide. 2019 Sep 18. pii: S1089-8603(19)30177-6. doi: 10.1016/j.niox.2019.09.006. [Epub ahead of print]

Human cystic fibrosis monocyte derived macrophages display no defect in acidification of phagolysosomes when measured by optical nanosensors.  Law SM1, Stanfield SJ2, Hardisty GR1, Dransfield I1, Campbell CJ2, Gray RD3.  J Cyst Fibros. 2019 Sep 6. pii: S1569-1993(18)30792-6. doi: 10.1016/j.jcf.2019.09.003. [Epub ahead of print]

Reduction in Oviposition of Poultry Red Mite (Dermanyssus gallinae) in Hens Vaccinated with Recombinant Akirin.  Lima-Barbero JF1,2, Contreras M3, Bartley K4, Price DRG5, Nunn F6, Sanchez-Sanchez M7, Prado E8, Höfle U9, Villar M10, Nisbet AJ11, de la Fuente J12,13. Vaccines (Basel). 2019 Sep 19;7(3). pii: E121. doi: 10.3390/vaccines7030121.

Comparing uptake across breast, cervical and bowel screening at an individual level: a retrospective cohort study.  McCowan C1, McSkimming P2, Papworth R2, Kotzur M3, McConnachie A2, Macdonald S4, Wyke S5, Crighton E6, Campbell C7, Weller D7, Steele RJC8, Robb KA3.  Br J Cancer. 2019 Sep 4. doi: 10.1038/s41416-019-0564-9. [Epub ahead of print]

Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study.  Meng X1, Li X1, Timofeeva MN2,3, He Y1,4, Spiliopoulou A5, Wei WQ6, Gifford A6, Wu H5, Varley T7, Joshi P1, Denny JC6, Farrington SM2,3, Zgaga L8, Dunlop MG2,3, McKeigue P5, Campbell H1, Theodoratou E1,3.  Int J Epidemiol. 2019 Sep 13. pii: dyz182. doi: 10.1093/ije/dyz182. [Epub ahead of print]

UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments.  Noad RJ1, Simpson K2, Fooks AR3, Hewson R4, Gilbert SC5, Stevens MP6, Hosie MJ7, Prior J8, Kinsey AM9, Entrican G10, Simpson A11, Whitty CJM12, Carroll MW13.  Vaccine. 2019 Sep 12. pii: S0264-410X(19)31197-1. doi: 10.1016/j.vaccine.2019.09.009. [Epub ahead of print]

A Porcine circovirus type 2b (PCV2b)-based experimental vaccine is effective in the PCV2b-Mycoplasma hyopneumoniae coinfection pig model.  Opriessnig T1, Castro AMMG2, Karuppanan AK3, Gauger PC3, Halbur PG3, Matzinger SR4, Meng XJ4.  Vaccine. 2019 Sep 16. pii: S0264-410X(19)31229-0. doi: 10.1016/j.vaccine.2019.09.029. [Epub ahead of print]

The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.  Rezansoff AM1, Laing R2, Martinelli A3, Stasiuk S1, Redman E1, Bartley D4, Holroyd N3, Devaney E2, Sargison ND5, Doyle S3, Cotton JA3, Gilleard JS6.  Int J Parasitol. 2019 Sep 13. pii: S0020-7519(19)30205-X. doi: 10.1016/j.ijpara.2019.05.012. [Epub ahead of print]

Transcriptomics Analysis of Porcine Caudal Dorsal Root Ganglia in Tail Amputated Pigs Shows Long-Term Effects on Many Pain-Associated Genes.  Sandercock DA1, Barnett MW2, Coe JE1, Downing AC3, Nirmal AJ2, Di Giminiani P4, Edwards SA4, Freeman TC2.  Front Vet Sci. 2019 Sep 18;6:314. doi: 10.3389/fvets.2019.00314. eCollection 2019.

Viral infection causes sex-specific changes in fruit fly social aggregation behaviour.  Siva-Jothy JA1, Vale PF1,2.  Biol Lett. 2019 Sep 27;15(9):20190344. doi: 10.1098/rsbl.2019.0344. Epub 2019 Sep 18.

Pressure regulates immune-cell function.  Walmsley SR.  Nature. 2019 Sep;573(7772):41-42. doi: 10.1038/d41586-019-02339-4.

Urinary estrogens as a non-invasive biomarker of viable pregnancy in the giant panda (Ailuropoda melanoleuca).  Wilson KS1, Wauters J2,3,4, Valentine I5, McNeilly A6, Girling S5, Li R7, Li D7, Zhang H7, Rae MT8, Howie F6, Andrew R9, Duncan WC6.  Sci Rep. 2019 Sep 4;9(1):12772. doi: 10.1038/s41598-019-49288-6.

Company matters: The presence of other genotypes alters traits and intraspecific selection in an Arctic diatom under climate change.   Wolf KKE1, Romanelli E1,2, Rost B1,3, John U1,4, Collins S5, Weigand H6, Hoppe CJM1.  Glob Chang Biol. 2019 Sep;25(9):2869-2884. doi: 10.1111/gcb.14675. Epub 2019 Jul 2.

Viral infection causes sex-specific changes in fruit fly social aggregation behaviour.  Wu P1,2, Gifford A3, Meng X4, Li X4, Campbell H4, Varley T5, Zhao J3, Carroll R3, Bastarache L3, Denny JC3,6, Theodoratou E4,7, Wei WQ1.  JMIR Med Inform. 2019 Sep 24. doi: 10.2196/14325. [Epub ahead of print]

August 2019

Regulation of Apoptotic Cell Clearance During Resolution of Inflammation.  Arienti S1, Barth ND1, Dorward DA1, Rossi AG1, Dransfield I1.  Front Pharmacol. 2019 Aug 13;10:891. doi: 10.3389/fphar.2019.00891. eCollection 2019.

Predicting vaccine effectiveness in livestock populations: A theoretical framework applied to PRRS virus infections in pigs.  Bitsouni V1, Lycett S1, Opriessnig T1,2, Doeschl-Wilson A1.  PLoS One. 2019 Aug 30;14(8):e0220738. doi: 10.1371/journal.pone.0220738. eCollection 2019.

Leveraging the Global Influenza Surveillance and Response System for global respiratory syncytial virus surveillance-opportunities and challenges.  Broor S1, Campbell H2, Hirve S3, Hague S4, Jackson S3, Moen A3, Nair H2, Palekar R5, Rajatonirina S6, Smith PG7, Venter M8, Wairagkar N9, Zambon M10, Ziegler T11, Zhang W3.  Influenza Other Respir Viruses. 2019 Aug 24. doi: 10.1111/irv.12672. [Epub ahead of print]

Predictive validity of a novel non-invasive estimation of effective shunt fraction in critically ill patients.  Chang EM1, Bretherick A1,2, Drummond GB1, Baillie JK3,4.  Intensive Care Med Exp. 2019 Aug 20;7(1):49. doi: 10.1186/s40635-019-0262-1.

Development of a deep amplicon sequencing method to determine the species composition of piroplasm haemoprotozoa.  Chaudhry U1, Ali Q2, Rashid I2, Shabbir MZ2, Ijaz M2, Abbas M3, Evans M4, Ashraf K2, Morrison I4, Morrison L4, Sargison ND4.  Ticks Tick Borne Dis. 2019 Aug 24:101276. doi: 10.1016/j.ttbdis.2019.101276. [Epub ahead of print]

Evolution, Microbes, and Changing Ocean Conditions.  Collins S1, Boyd PW2, Doblin MA3.  Ann Rev Mar Sci. 2019 Aug 26. doi: 10.1146/annurev-marine-010318-095311. [Epub ahead of print]

Future Trends in Synthetic Biology-A Report.  El Karoui M1, Hoyos-Flight M2, Fletcher L1.  Front Bioeng Biotechnol. 2019 Aug 7;7:175. doi: 10.3389/fbioe.2019.00175. eCollection 2019.

Disparity in endometriosis diagnoses between racial/ethnic groups.  Farland LV1, Horne AW2.  BJOG. 2019 Aug;126(9):1115-1116. doi: 10.1111/1471-0528.15805. Epub 2019 May 21.

Consistent within-individual plasticity is sufficient to explain temperature responses in red deer reproductive traits.  Froy H1, Martin J2, Stopher KV1, Morris A1, Morris S1, Clutton-Brock TH3, Pemberton JM1, Kruuk LEB1,4.  J Evol Biol. 2019 Aug 17. doi: 10.1111/jeb.13521. [Epub ahead of print]

Evidence of Leptospira species and their significance during reintroduction of Eurasian beavers (Castor fiber) to Great Britain.  Girling SJ1, Goodman G2, Burr P3, Pizzi R4, Naylor A4, Cole G4, Brown D4, Fraser M5, Rosell FN6, Schwab G7, Elliott M8, Campbell-Palmer R9.  Vet Rec. 2019 Aug 29. pii: vetrec-2019-105429. doi: 10.1136/vr.105429. [Epub ahead of print]

The effects of individual nonheritable variation on fitness estimation and coexistence.  Gomes MGM1,2, King JG3, Nunes A4, Colegrave N3, Hoffmann AA5.  Ecol Evol. 2019 Aug 1;9(16):8995-9004. doi: 10.1002/ece3.5437. eCollection 2019 Aug.

The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial.  Harvie M1,2, Pegington M3,4, McMullan D3, Bundred N5,4, Livingstone K6, Campbell A7, Wolstenholme J8, Lovato E8, Campbell H9, Adams J10, Speed S11, Morris J12, Howell S5,4,13, Howell A3,5,4.  Br J Cancer. 2019 Aug 1. doi: 10.1038/s41416-019-0522-6. [Epub ahead of print]

Moving forward: Bronchiectasis and chronic suppurative lung disease in children and adults in the 21st century.  Hill AT1,2, Chang AB3,4.  Respirology. 2019 Aug 19. doi: 10.1111/resp.13670. [Epub ahead of print]

Datafication and accountability in public health: Introduction to a special issue.  Hoeyer K1, Bauer S2, Pickersgill M3.  Soc Stud Sci. 2019 Aug;49(4):459-475. doi: 10.1177/0306312719860202.

Analysis of the impact of CSF-1 administration in adult rats using a novel Csf1r-mApple reporter gene.  Irvine KM1, Caruso M1, Cestari MF1, Davis GM2, Keshvari S1, Sehgal A1, Pridans C3, Hume DA1,3.  J Leukoc Biol. 2019 Aug 8. doi: 10.1002/JLB.MA0519-149R. [Epub ahead of print]

Transcriptional response of ovine lung to infection with jaagsiekte sheep retrovirus.  Karagianni AE1, Vasoya D2, Finlayson J1, Martineau HM1, Wood AR1, Cousens C1, Dagleish MP1, Watson M2, Griffiths DJ3.  J Virol. 2019 Aug 21. pii: JVI.00876-19. doi: 10.1128/JVI.00876-19. [Epub ahead of print]

Dynamic optical rectification and delivery of active particles. Koumakis N1, Brown AT1, Arlt J1, Griffiths SE1, Martinez VA1, Poon WCK1.  Soft Matter. 2019 Aug 22. doi: 10.1039/c9sm00799g. [Epub ahead of print]

Survival costs of reproduction are mediated by parasite infection in wild Soay sheep.  Leivesley JA1, Bussière LF1, Pemberton JM2, Pilkington JG2,3, Wilson K4, Hayward AD1.  Ecol Lett. 2019 Aug;22(8):1203-1213. doi: 10.1111/ele.13275. Epub 2019 May 20.

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis.  Li Y1, Reeves RM1, Wang X1, Bassat Q2, Brooks WA3, Cohen C4, Moore DP5, Nunes M6, Rath B7, Campbell H1, Nair H8; RSV Global Epidemiology Network; RESCEU investigators.  Lancet Glob Health. 2019 Aug;7(8):e1031-e1045. doi: 10.1016/S2214-109X(19)30264-5.

Identification of Rumen Microbial Genes Involved in Pathways Linked to Appetite, Growth, and Feed Conversion Efficiency in Cattle.  Lima J1, Auffret MD1, Stewart RD2, Dewhurst RJ1, Duthie CA1, Snelling TJ3, Walker AW3, Freeman TC2, Watson M2, Roehe R1.  Front Genet. 2019 Aug 8;10:701. doi: 10.3389/fgene.2019.00701. eCollection 2019.

Engineered CRISPRa enables programmable eukaryote-like gene activation in bacteria.  Liu Y1,2, Wan X1,2, Wang B3,4.  Nat Commun. 2019 Aug 26;10(1):3693. doi: 10.1038/s41467-019-11479-0.

Efficacy and safety of tobramycin inhalation powder in bronchiectasis patients with P. aeruginosa infection: Design of a dose-finding study (iBEST-1).  Loebinger MR1, Polverino E2, Blasi F3, Elborn SJ4, Chalmers JD5, Tiddens HA6, Goossens H7, Tunney M8, Zhou W9, Angyalosi G9, Hill AT10, Haworth CS11; iBEST-1 Trial Team.  Pulm Pharmacol Ther. 2019 Aug 18;58:101834. doi: 10.1016/j.pupt.2019.101834. [Epub ahead of print]

High genetic diversity and recombination events of porcine astrovirus strains identified from ill and asymptomatic pigs in 2017, Hunan Province, China.  Lv SL1, Zhang HH1, Li JY1, Hu WQ1, Song YT1, Opriessnig T2, Xiao CT3.  Virus Genes. 2019 Aug 1. doi: 10.1007/s11262-019-01692-w. [Epub ahead of print]

Risk factors associated with excessive negative energy balance in commercial United Kingdom dairy herds.  Macrae AI1, Burrough E2, Forrest J2, Corbishley A2, Russell G2, Shaw DJ3.  Vet J. 2019 Aug;250:15-23. doi: 10.1016/j.tvjl.2019.06.001. Epub 2019 Jun 11.

A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites.  McCormick B1, Craig HE2, Chu JY1, Carlin LM3,4, Canel M1, Wollweber F1, Toivakka M1, Michael M1, Astier AL1,5, Norton L2, Lilja J6, Felton JM1, Sasaki T7, Ivaska J5, Hers I8, Dransfield I1, Rossi AG1, Vermeren S9.  J Immunol. 2019 Aug 19. pii: ji1900443. doi: 10.4049/jimmunol.1900443. [Epub ahead of print]

Rosetting revisited: a critical look at the evidence for host erythrocyte receptors in Plasmodium falciparum rosetting.  McQuaid F1, Rowe JA1.  Parasitology. 2019 Aug 28:1-43. doi: 10.1017/S0031182019001288. [Epub ahead of print]

Epidemiology of antimicrobial resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanising city.  Muloi D1, Kiiru J2, Ward MJ3, Hassell JM4, Bettridge JM4, Robinson TP5, van Bunnik BAD6, Chase-Topping M7, Robertson G8, Pedersen AB9, Fèvre EM4, Woolhouse MEJ6, Kang'ethe EK10, Kariuki S2.  Int J Antimicrob Agents. 2019 Aug 19. pii: S0924-8579(19)30225-0. doi: 10.1016/j.ijantimicag.2019.08.014. [Epub ahead of print]

Defining primary palliative care for universal health coverage.  Munday D1, Boyd K2, Jeba J3, Kimani K4, Moine S2, Grant L2, Murray S2.  Lancet. 2019 Aug 24;394(10199):621-622. doi: 10.1016/S0140-6736(19)31830-6.

A Dual Killing Strategy: Photocatalytic Generation of Singlet Oxygen with Concomitant PtIV Prodrug Activation.  Norman DJ1, Gambardella A1, Mount AR1, Murray AF2, Bradley M1.  Angew Chem Int Ed Engl. 2019 Aug 9. doi: 10.1002/anie.201908511. [Epub ahead of print]

Sex increases the probability of evolutionary rescue in the presence of a competitor.  Petkovic N1, Colegrave N1.  J Evol Biol. 2019 Aug 20. doi: 10.1111/jeb.13525. [Epub ahead of print].

Multi-host disease management: the why and the how to include wildlife.  Portier J1, Ryser-Degiorgis MP2, Hutchings MR3, Monchâtre-Leroy E4, Richomme C4, Larrat S5, van der Poel WHM6, Dominguez M7, Linden A8, Santos PT9 et al.  BMC Vet Res. 2019 Aug 14;15(1):295. doi: 10.1186/s12917-019-2030-6.

Quorum sensing in African trypanosomes.  Rojas F1, Matthews KR2.  Curr Opin Microbiol. 2019 Aug 20;52:124-129. doi: 10.1016/j.mib.2019.07.001. [Epub ahead of print].

Network analysis of canine brain morphometry links tumour risk to oestrogen deficiency and accelerated brain ageing.  Rzechorzek NM1,2,3, Saunders OM4, Hiscox LV5,6, Schwarz T4, Marioni-Henry K4, Argyle DJ4, Schoenebeck JJ4, Freeman TC4.  Sci Rep. 2019 Aug 29;9(1):12506. doi: 10.1038/s41598-019-48446-0.

Development of amplicon sequencing for the analysis of benzimidazole resistance allele frequencies in field populations of gastrointestinal nematodes.  Sargison ND1, MacLeay M1, Morrison AA2, Bartley DJ2, Evans M1, Chaudhry U3.  Int J Parasitol Drugs Drug Resist. 2019 Aug 13;10:92-100. doi: 10.1016/j.ijpddr.2019.08.003. [Epub ahead of print]

Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT.  Scarborough M1, Li HK1,2, Rombach I3, Zambellas R3, Walker AS4,5, McNally M1, Atkins B1, Kümin M5, Lipsky BA6, Hughes H7, Bose D8 et al.  Health Technol Assess. 2019 Aug;23(38):1-92. doi: 10.3310/hta23380.

Differential nanoscale organisation of LFA-1 modulates T cell migration.  Shannon MJ1, Pineau J1, Griffié J1, Aaron J2, Peel T3, Williamson DJ1, Zamoyska R4, Cope AP3, Cornish GH3, Owen DM5,6.  J Cell Sci. 2019 Aug 30. pii: jcs.232991. doi: 10.1242/jcs.232991. [Epub ahead of print]

Association Between Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection in Early Life and Recurrent Wheeze and Asthma in Later Childhood.  Shi T1, Ooi Y1, Zaw EM1, Utjesanovic N1, Campbell H1, Cunningham S2,3, Bont L4,5, Nair H1,5; RESCEU Investigators.  J Infect Dis. 2019 Aug 1. pii: jiz311. doi: 10.1093/infdis/jiz311. [Epub ahead of print]

A role for S-nitrosylation of the SUMO-conjugating enzyme SCE1 in plant immunity.  Skelly MJ1, Malik SI1, Le Bihan T2, Bo Y3, Jiang J3,4, Spoel SH1, Loake GJ5,2,4.  Proc Natl Acad Sci U S A. 2019 Aug 1. pii: 201900052. doi: 10.1073/pnas.1900052116. [Epub ahead of print]

Fluoroquinolones and isoniazid resistant TB: implications for the 2018 WHO guidance.  Stagg HR1,2, Bothamley GH3, Davidson JA4, Kunst H5, Lalor MK6,4, Lipman MC7,8, Loutet MG4, Lozewicz S9, Mohiyuddin T4, Abbara A10 et al.  Eur Respir J. 2019 Aug 1. pii: 1900982. doi: 10.1183/13993003.00982-2019. [Epub ahead of print]

Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag.  Stucke EM1, Niangaly A2, Berry AA1, Bailey JA3, Coulibaly D2, Ouattara A1, Lyke KE1, Laurens MB1, Dara A2, Adams M1 et al.  Malar J. 2019 Aug 13;18(1):273. doi: 10.1186/s12936-019-2905-9.

FAM19A4/miR124-2 methylation in invasive cervical cancer: A retrospective cross-sectional worldwide study.  Vink FJ1, Meijer CJLM1, Clifford GM2, Poljak M3, Oštrbenk A3, Petry KU4, Rothe B5, Bonde J6, Pedersen H6 et al.  Int J Cancer. 2019 Aug 7. doi: 10.1002/ijc.32614. [Epub ahead of print]

Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and NK Cell Function.  Wagstaffe HR1, Pickering H2, Houghton J2, Mooney JP1,3, Wolf AS1,4, Prevatt N2, Behrens RH2, Holland MJ2, Riley EM1,3, Goodier MR5.  J Immunol. 2019 Aug 19. pii: ji1801648. doi: 10.4049/jimmunol.1801648. [Epub ahead of print]

Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.  Zhong W1, Guo J2, Cui L3, Chionh YH3, Li K4, El Sahili A5, Cai Q6, Yuan M7, Michels PAM7, Fothergill-Gilmore LA7, Walkinshaw MD7, Mu Y8, Lescar J9, Dedon PC10.  J Mol Biol. 2019 Aug 2. pii: S0022-2836(19)30484-X. doi: 10.1016/j.jmb.2019.07.033. [Epub ahead of print]

July 2019

High-Performance Computing in Bayesian Phylogenetics and Phylodynamics Using BEAGLE.  Baele G1, Ayres DL2, Rambaut A3, Suchard MA4, Lemey P5.  Methods Mol Biol. 2019;1910:691-722. doi: 10.1007/978-1-4939-9074-0_23.

Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages.  Belchamber KBR1, Singh R1, Batista CM1, Whyte MK2, Dockrell DH2, Kilty I3, Robinson MJ4, Wedzicha JA1, Barnes PJ1, Donnelly LE5; COPDMAP consortium.  Eur Respir J. 2019 Jul 18. pii: 1802244. doi: 10.1183/13993003.02244-2018. [Epub ahead of print]

Plasticity and genetic variation in traits underpinning asexual replication of the rodent malaria parasite, Plasmodium chabaudi.  Birget PLG1,2, Prior KF3,4, Savill NJ1,2, Steer L1,2, Reece SE1,2.  Malar J. 2019 Jul 1;18(1):222. doi: 10.1186/s12936-019-2857-0.

Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic.  Cholewa-Waclaw J1, Shah R1, Webb S1, Chhatbar K1, Ramsahoye B2, Pusch O3, Yu M4, Greulich P5,6, Waclaw B7, Bird AP8.  Proc Natl Acad Sci U S A. 2019 Jul 9. pii: 201903549. doi: 10.1073/pnas.1903549116. [Epub ahead of print]

Patterns of population structure and complex haplotype sharing among field isolates of the green alga Chlamydomonas reinhardtii.  Craig RJ1,2, Böndel KB1,3, Arakawa K4,5, Nakada T4,5,6, Ito T4,5, Bell G7, Colegrave N1, Keightley PD1, Ness RW2.  Mol Ecol. 2019 Jul 23. doi: 10.1111/mec.15193. [Epub ahead of print]

Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine.  de Steenhuijsen Piters WAA1,2,3, Jochems SP4, Mitsi E4, Rylance J4, Pojar S4, Nikolaou E4, German EL4, Holloway M4, Carniel BF4, Chu MLJN1,2, Arp K1,2, Sanders EAM1, Ferreira DM4, Bogaert D5,6,7.  Nat Commun. 2019 Jul 5;10(1):2981. doi: 10.1038/s41467-019-10814-9.

Lipidomics, Atrial Conduction, and Body Mass Index.  Del Greco M F, Foco L1, Teumer A2, Verweij N3, Paglia G1, Meraviglia V4, Melotti R1, Vukovic V1, Rauhe W5, Joshi PK6, Demirkan A7,8, Felix SB2, Pietzner M9,10 et al.  Circ Genom Precis Med. 2019 Jul;12(7):e002384. doi: 10.1161/CIRCGEN.118.002384. Epub 2019 Jul 15.

Human Adenovirus Serotype 5 Is Sensitive to IgM-Independent Neutralization In Vitro and In Vivo.  Doszpoly A1, de la Cuesta F1, Lopez-Gordo E2, Bénézech C1, Nicklin SA2, Baker AH3.  Viruses. 2019 Jul 5;11(7). pii: E616. doi: 10.3390/v11070616.

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.  Evangelou E1,2, Gao H1,3, Chu C4, Ntritsos G2, Blakeley P1,5, Butts AR6, Pazoki R1, Suzuki H7,8, Koskeridis F2, Yiorkas AM9,10, Karaman I1,11, Elliott J1 et al.  Nat Hum Behav. 2019 Jul 29. doi: 10.1038/s41562-019-0653-z. [Epub ahead of print]

Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis.  Forster R1, Sarginson A1, Velichkova A1, Hogg C1, Dorning A1, Horne AW1, Saunders PTK2, Greaves E3.  FASEB J. 2019 Jul 10:fj201900797R. doi: 10.1096/fj.201900797R. [Epub ahead of print]

Potential of Genome Editing to Improve Aquaculture Breeding and Production.  Gratacap RL1, Wargelius A2, Edvardsen RB2, Houston RD3.  Trends Genet. 2019 Jul 19. pii: S0168-9525(19)30126-X. doi: 10.1016/j.tig.2019.06.006. [Epub ahead of print]

Effects of common genetic variants associated with colorectal cancer risk on survival outcomes after diagnosis: a large population-based cohort study.  He Y1,2,3, Theodoratou E1,3, Li X3, Din FV1,2, Vaughan-Shaw P2, Svinti V2, Farrington SM1,2, Campbell H3, Dunlop MG1,2, Timofeeva M1,2.  Int J Cancer. 2019 Jul 4. doi: 10.1002/ijc.32550. [Epub ahead of print]

Cell Biology of Intracellular Adaptation of Mycobacterium leprae in the Peripheral Nervous System.  Hess S1, Rambukkana A1.  Microbiol Spectr. 2019 Jul;7(4). doi: 10.1128/microbiolspec.BAI-0020-2019.

A prime-boost concept using a T-cell epitope-driven DNA vaccine followed by a whole virus vaccine effectively protected pigs in the pandemic H1N1 pig challenge model.  Hewitt JS1, Karuppannan AK1, Tan S2, Gauger P1, Halbur PG1, Gerber PF3, De Groot AS4, Moise L4, Opriessnig T5.  Vaccine. 2019 Jul 18;37(31):4302-4309. doi: 10.1016/j.vaccine.2019.06.044. Epub 2019 Jun 24.

Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink?  Horne AW1, Daniels J2, Hummelshoj L3, Cox E4, Cooper KG5.  BJOG. 2019 Jul 29. doi: 10.1111/1471-0528.15894. [Epub ahead of print]

Pedigree-Based Estimation of Reproductive Value.  Hunter DC1, Pemberton JM1,2, Pilkington JG1, Morrissey MB1.  J Hered. 2019 Jul 1;110(4):433-444. doi: 10.1093/jhered/esz033.

Metagenomic Next-Generation Sequencing of the 2014 Ebola Virus Disease Outbreak in the Democratic Republic of the Congo.  Li T1,2, Mbala-Kingebeni P3, Naccache SN1,2, Thézé J4, Bouquet J1,2, Federman S1,2, Somasekar S1,2, Yu G1,2, Sanchez-San Martin C1,2 et al.  J Clin Microbiol. 2019 Jul 17. pii: JCM.00827-19. doi: 10.1128/JCM.00827-19. [Epub ahead of print]

Streptococcus hillyeri sp. nov., isolated from equine trachea.  MacFadyen AC1, Waller AS2, Paterson GK1.  Int J Syst Evol Microbiol. 2019 Jul 9. doi: 10.1099/ijsem.0.003489. [Epub ahead of print]

Spt5 modulates co-transcriptional spliceosome assembly in Saccharomyces cerevisiae.  Maudlin IE1, Beggs JD2.  RNA. 2019 Jul 9. pii: rna.070425.119. doi: 10.1261/rna.070425.119. [Epub ahead of print]

Visualization and analysis of RNA-Seq assembly graphs.  Nazarie FW1, Shih B1, Angus T1, Barnett MW1, Chen SH1, Summers KM2,3, Klein K4, Faulkner GJ3, Saini HK5, Watson M2, Dongen SV6, Enright AJ7, Freeman TC1.  Nucleic Acids Res. 2019 Jul 15. pii: gkz599. doi: 10.1093/nar/gkz599. [Epub ahead of print]

Time-of-day of blood-feeding: effects on mosquito life history and malaria transmission.  O'Donnell AJ1, Rund SSC2, Reece SE3.  Parasit Vectors. 2019 Jul 2;12(1):301. doi: 10.1186/s13071-019-3513-9.

Domestication of Campylobacter jejuni NCTC 11168.  Pascoe B1,2, Williams LK3, Calland JK1, Meric G1,4,5, Hitchings MD3, Dyer M3, Ryder J1, Shaw S6, Lopes BS6, Chintoan-Uta C7, Allan E8, Vidal A9 et al.  Microb Genom. 2019 Jul 16. doi: 10.1099/mgen.0.000279. [Epub ahead of print]

Psychiatry and the Sociology of Novelty: Negotiating the US National Institute of Mental Health "Research Domain Criteria" (RDoC).  Pickersgill M1.  Sci Technol Human Values. 2019 Jul;44(4):612-633. doi: 10.1177/0162243919841693. Epub 2019 Apr 12.

Changes in the ileal, but not fecal, microbiome in response to increased dietary protein level and enterotoxigenic Escherichia coli exposure in pigs.  Pollock J1,2, Hutchings MR3, Hutchings KEK3, Gally DL2, Houdijk JGM3.  Appl Environ Microbiol. 2019 Jul 19. pii: AEM.01252-19. doi: 10.1128/AEM.01252-19. [Epub ahead of print]

Characterisation of a niche-specific excretory-secretory peroxiredoxin from the parasitic nematode Teladorsagia circumcincta.  Price DRG1, Nisbet AJ2, Frew D2, Bartley Y2, Oliver EM2, McLean K2, Inglis NF2, Watson E2, Corripio-Miyar Y2, McNeilly TN2.  Parasit Vectors. 2019 Jul 10;12(1):339. doi: 10.1186/s13071-019-3593-6.

Host circadian rhythms are disrupted during malaria infection in parasite genotype-specific manners.  Prior KF1, O'Donnell AJ2, Rund SSC3, Savill NJ2, van der Veen DR4, Reece SE2.  Sci Rep. 2019 Jul 29;9(1):10905. doi: 10.1038/s41598-019-47191-8.

Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae.  Richards VP1,2, Velsko IM2,3, Alam T2,4, Zadoks RN5,6, Manning SD7, Pavinski Bitar PD1, Hasler HB2, Crestani C5, Springer G2, Probert B2, Town CD8, Stanhope MJ1.  Mol Biol Evol. 2019 Jul 27. pii: msz169. doi: 10.1093/molbev/msz169. [Epub ahead of print]

Variation in the prion protein gene (PRNP) sequence of wild deer in Great Britain and mainland Europe.  Robinson AL1, Williamson H2, Güere ME3, Tharaldsen H3, Baker K4, Smith SL5, Pérez-Espona S2,5, Krojerová-Prokešová J6,7, Pemberton JM8, Goldmann W2, Houston F2.  Vet Res. 2019 Jul 31;50(1):59. doi: 10.1186/s13567-019-0675-6.

Rabbit haemorrhagic disease virus type 2 in hares in Scotland.  Rocchi M1, Maley M1, Dagleish M1, Boag B2.  Vet Rec. 2019 Jul 6;185(1):23. doi: 10.1136/vr.l4481. 

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations.  Rojo R1,2, Raper A1, Ozdemir DD1, Lefevre L1, Grabert K1,3, Wollscheid-Lengeling E1, Bradford B1, Caruso M1, Gazova I1, Sánchez A1 et al.  Nat Commun. 2019 Jul 19;10(1):3215. doi: 10.1038/s41467-019-11053-8.

Strengthening national health research systems in the WHO African Region - progress towards universal health coverage.  Rusakaniko S1,2, Makanga M3, Ota MO4, Bockarie M3, Banda G1, Okeibunor J5, Mutapi F6, Tumusiime P5, Nyirenda T3, Kirigia JM7, Nabyonga-Orem J8.  Global Health. 2019 Jul 26;15(1):50. doi: 10.1186/s12992-019-0492-8.

Draft genome sequence of a multidrug-resistant caprine isolate of Staphylococcus cohnii subsp. urealyticus from Tanzania encoding ermB, tet(K), dfrG, fusF and fosD.  Seni J1, Mshana SE1, Msigwa F1, Iddi S2, Mazigo H3, Parkhill J4, Holmes MA5, Paterson GK6.  J Glob Antimicrob Resist. 2019 Jul 16;18:163-165. doi: 10.1016/j.jgar.2019.07.006. [Epub ahead of print]

A bridge to normal': a qualitative study of Indonesian women's attendance in a phase two cardiac rehabilitation programme.  Sutantri S1,2, Cuthill F1, Holloway A1.  Eur J Cardiovasc Nurs. 2019 Jul 21:1474515119864208. doi: 10.1177/1474515119864208. [Epub ahead of print]

Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation.  Szöőr B1, Simon DV2, Rojas F2, Young J2, Robinson DR3, Krüger T4, Engstler M4, Matthews KR1.  MBio. 2019 Jul 9;10(4). pii: e00875-19. doi: 10.1128/mBio.00875-19.

Shedding of Cryptosporidium in calves and dams: evidence of re-infection and shedding of different gp60 subtypes.  Thomson S1, Innes EA1, Jonsson NN2, Katzer F1.  Parasitology. 2019 Jul 22:1-10. doi: 10.1017/S0031182019000829. [Epub ahead of print]

The bereaved parent.  Wallace E1.  Elife. 2019 Jul 8;8. pii: e49932. doi: 10.7554/eLife.49932.

Quantitative Proteomics Reveals Differences in the Response of Neutrophils Isolated from Healthy or Diabetic Subjects to Infection with Capsule-Variant Burkholderia thailandensis.  Withatanung P1, Kurian D2, Tangjittipokin W1, Plengvidhya N3, Titball RW4, Korbsrisate S1, Stevens JM2.  J Proteome Res. 2019 Jul 5;18(7):2848-2858. doi: 10.1021/acs.jproteome.9b00166. Epub 2019 Jun 21.

June 2019

Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model.  Akram AR1, Avlonitis N2, Scholefield E3, Vendrell M3, McDonald N3, Aslam T2, Craven TH3, Gray C4, Collie DS5, Fisher AJ6, Corris PA6, Walsh T3, Haslett C3, Bradley M7,8, Dhaliwal K9.  Sci Rep. 2019 Jun 10;9(1):8422. doi: 10.1038/s41598-019-44804-0.

Ethical considerations in the use of GPS-based movement tracking in health research - lessons from a care-seeking study in rural west India.  Apte A1, Ingole V1,2, Lele P1, Marsh A1,3, Bhattacharjee T1,4, Hirve S1, Campbell H5, Nair H5, Chan S5, Juvekar S1.  J Glob Health. 2019 Jun;9(1):010323. doi: 10.7189/jogh.09.010323.

Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii.  Böndel KB1, Kraemer SA1,2, Samuels T1, McClean D3, Lachapelle J4, Ness RW4, Colegrave N1, Keightley PD1.  PLoS Biol. 2019 Jun 26;17(6):e3000192. doi: 10.1371/journal.pbio.3000192. eCollection 2019 Jun.

Successful reintroduction of tumour necrosis factor-alpha inhibition after treatment of disseminated Lyme borreliosis.  Bulteel NS#1, Russell CD2,3, Perry MR2,4, Koch O2.  J R Coll Physicians Edinb. 2019 Jun;49(2):122-124. doi: 10.4997/JRCPE.2019.207.

Tissue-Engineering the Intestine: The Trials before the Trials.  Clevers H1, Conder RK2, Li VSW3, Lutolf MP4, Vallier L5, Chan S6, Grikscheit TC7, Jensen KB8, De Coppi P9.  Cell Stem Cell. 2019 Jun 6;24(6):855-859. doi: 10.1016/j.stem.2019.04.018.

Radical polymerization inside living cells.  Geng J1, Li W1, Zhang Y1, Thottappillil N1, Clavadetscher J1, Lilienkampf A1, Bradley M2.  Nat Chem. 2019 Jun;11(6):578-586. doi: 10.1038/s41557-019-0240-y. Epub 2019 Apr 15.

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.   Georgiadou A1, Lee HJ2,3, Walther M4, van Beek AE5,6, Fitriani F1, Wouters D5,7, Kuijpers TW6,8, Nwakanma D4 et al. Nat Microbiol. 2019 Jun 17. doi: 10.1038/s41564-019-0474-x. [Epub ahead of print]

Modelling the dynamics of EBV transmission to inform a vaccine target product profile and future vaccination strategy.  Goscé L1, Winter JR2, Taylor GS3, Lewis JEA4, Stagg HR2,5.  Sci Rep. 2019 Jun 26;9(1):9290. doi: 10.1038/s41598-019-45381-y.

Primary care implications of the British Thoracic Society Guidelines for bronchiectasis in adults 2019.  Gruffydd-Jones K1, Keeley D2, Knowles V3, Recabarren X4, Woodward A5, Sullivan AL6, Loebinger MR7, Payne K8, Harvey A9, Grillo L10, Welham SA11, Hill AT12.  NPJ Prim Care Respir Med. 2019 Jun 27;29(1):24. doi: 10.1038/s41533-019-0136-8.

Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus.  Harrison EM1,2,3, Ba X4, Coll F5, Blane B6, Restif O4, Carvell H7, Köser CU8, Jamrozy D9, Reuter S10, Lovering A11, Gleadall N6 et al.  Nat Microbiol. 2019 Jun 24. doi: 10.1038/s41564-019-0471-0. [Epub ahead of print]

Clinically relevant antimicrobial resistance at the wildlife-livestock-human interface in Nairobi: an epidemiological study.  Hassell JM1, Ward MJ2, Muloi D3, Bettridge JM1, Robinson TP4, Kariuki S5, Ogendo A6, Kiiru J5, Imboma T7, Kang'ethe EK8, Öghren EM9, Williams NJ10, Begon M11, Woolhouse MEJ12, Fèvre EM13.  Lancet Planet Health. 2019 Jun;3(6):e259-e269. doi: 10.1016/S2542-5196(19)30083-X.

Deterministic processes structure bacterial genetic communities across an urban landscape.  Hassell JM1,2, Ward MJ3,4, Muloi D5,3,6, Bettridge JM7,5, Phan H4,8, Robinson TP9, Ogendo A5, Imboma T10, Kiiru J11, Kariuki S11, Begon M12, Kang'ethe EK13, Woolhouse MEJ3,6, Fèvre EM14,15.  Nat Commun. 2019 Jun 14;10(1):2643. doi: 10.1038/s41467-019-10595-1.

Performance of prediction models on survival outcomes of colorectal cancer with surgical resection: A systematic review and meta-analysis.  He Y1, Ong Y2, Li X3, Din FV4, Brown E5, Timofeeva M4, Wang Z6, Farrington SM4, Campbell H3, Dunlop MG4, Theodoratou E7.  Surg Oncol. 2019 Jun;29:196-202. doi: 10.1016/j.suronc.2019.05.014. Epub 2019 May 20.

Sublethal effects of natural parasitism act through maternal, but not paternal; reproductive success in a wild population.  Hicks O1, Green JA1, Daunt F2, Cunningham EJA3, Newell M2, Butler A4, Burthe SJ2.  Ecology. 2019 Jun 5:e02772. doi: 10.1002/ecy.2772. [Epub ahead of print]

Cumulative weather effects can impact across the whole life cycle.  Hindle BJ1,2, Pilkington JG3, Pemberton JM3, Childs DZ1.  Glob Chang Biol. 2019 Jun 25. doi: 10.1111/gcb.14742. [Epub ahead of print]

High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.  Hollis RL1, Churchman M1, Michie CO1, Rye T1, Knight L2, McCavigan A2, Perren T3, Williams ARW4 et al.  Cancer. 2019 Jun 2. doi: 10.1002/cncr.32079. [Epub ahead of print]

Segment 2 from influenza A(H1N1) 2009 pandemic viruses confers temperature-sensitive haemagglutinin yield on candidate vaccine virus growth in eggs that can be epistatically complemented by PB2 701D.  Hussain S1,2, Turnbull ML2, Pinto RM2, McCauley JW1, Engelhardt OG3, Digard P2.  J Gen Virol. 2019 Jun 6. doi: 10.1099/jgv.0.001279. [Epub ahead of print]

What does the Malawi Demographic and Health Survey say about the country's first Health Sector Strategic Plan?  Kawale P1,2, Pagliari C2, Grant L2.  J Glob Health. 2019 Jun;9(1):010314. doi: 10.7189/jogh.09.010314. 

A landscape review of the published research output relating to respiratory syncytial virus (RSV) in North & Central America and Europe between 2011-2015.  Kirolos A1, Christides A1, Xian S1, Reeves R2,1, Nair H2,1, Campbell H2,1.  J Glob Health. 2019 Jun;9(1):010425. doi: 10.7189/jogh.09.010425.

A brief history of bird flu.  Lycett SJ1, Duchatel F1, Digard P1.  Philos Trans R Soc Lond B Biol Sci. 2019 Jun 24;374(1775):20180257. doi: 10.1098/rstb.2018.0257.

Staphylococcus pseudoxylosus sp. nov., isolated from bovine mastitis.  MacFadyen AC1, Leroy S2, Harrison EM3, Parkhill J3, Holmes MA4, Paterson GK1.  Int J Syst Evol Microbiol. 2019 Jun 21. doi: 10.1099/ijsem.0.003416. [Epub ahead of print]

Prevalence of excessive negative energy balance in commercial United Kingdom dairy herds.  Macrae AI1, Burrough E2, Forrest J2, Corbishley A2, Russell G2, Shaw DJ3.  Vet J. 2019 Jun;248:51-57. doi: 10.1016/j.tvjl.2019.04.001. Epub 2019 Apr 5.

Whole Genome Sequence Analysis Reveals Lower Diversity and Frequency of Acquired Antimicrobial Resistance (AMR) Genes in E. coli From Dairy Herds Compared With Human Isolates From the Same Region of Central Zambia.  Mainda G1,2, Lupolova N1, Sikakwa L3, Richardson E4, Bessell PR1, Malama SK3, Kwenda G3, Stevens MP1, Bronsvoort BMD1, Muma JB3, Gally DL1.  Front Microbiol. 2019 May 31;10:1114. doi: 10.3389/fmicb.2019.01114. eCollection 2019.

Epilepsia partialis continua complicated by disseminated tuberculosis and hemophagocytic lymphohistiocytosis: a case report.  Mbizvo GK1,2, Lentell IC3, Leen C4, Roddie H5, Derry CP6,7, Duncan SE8,6, Rannikmäe K9.  J Med Case Rep. 2019 Jun 24;13(1):191. doi: 10.1186/s13256-019-2092-x.

Endosymbionts interaction with trypanosomes in Palpalis group of Glossina captured in southwest Nigeria.  Odeniran PO1, Macleod ET2, Ademola IO3, Welburn SC4.  Parasitol Int. 2019 Jun;70:64-69. doi: 10.1016/j.parint.2019.01.011. Epub 2019 Feb 1.

Evaluation of the nutritive value of legume alternatives to soybean meal for broiler chickens.  Olukosi OA1,2, Walker RL3, Houdijk JGM1.  Poult Sci. 2019 Jun 27. pii: pez374. doi: 10.3382/ps/pez374. [Epub ahead of print]

The relationship between the presence of antibodies and direct detection of Toxoplasma gondii in slaughtered calves and cattle in four European countries.  Opsteegh M1, Spano F2, Aubert D3, Balea A4, Burrells A5, Cherchi S2, Cornelissen JBWJ6, Dam-Deisz C7, Guitian J8, Györke A4 et al.  Int J Parasitol. 2019 Jun;49(7):515-522. doi: 10.1016/j.ijpara.2019.01.005. Epub 2019 May 17.

Optimizing Genomic Prediction of Host Resistance to Koi Herpesvirus Disease in Carp.  Palaiokostas C1,2, Vesely T3, Kocour M4, Prchal M4, Pokorova D3, Piackova V4, Pojezdal L3, Houston RD1.  Front Genet. 2019 Jun 12;10:543. doi: 10.3389/fgene.2019.00543. eCollection 2019.

Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion.  Pickering AC1, Vitry P2, Prystopiuk V2, Garcia B3, Höök M4, Schoenebeck J5, Geoghegan JA6, Dufrêne YF2,7, Fitzgerald JR1.  PLoS Pathog. 2019 Jun 19;15(6):e1007816. doi: 10.1371/journal.ppat.1007816. eCollection 2019 Jun.

Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in Chronic Obstructive Pulmonary Disease. More Than a Common Cold.  Sabroe I1,2, Ho A3, Dockrell DH4,5.  Am J Respir Crit Care Med. 2019 Jun 15;199(12):1451-1452. doi: 10.1164/rccm.201812-2283ED.

The use of brain functional magnetic resonance imaging to determine the mechanism of action of gabapentin in managing chronic pelvic pain in women: a pilot study.  Seretny M1, Murray SR2, Whitaker L2, Murnane J3, Whalley H4, Pernet C3, Horne AW2.  BMJ Open. 2019 Jun 27;9(6):e026152. doi: 10.1136/bmjopen-2018-026152.

Defining the genetic control of human blood plasma N-glycome using genome-wide association study.  Sharapov SZ1,2, Tsepilov YA1,2, Klaric L3,4, Mangino M5,6, Thareja G7, Shadrina AS2, Simurina M8, Dagostino C9 et al.  Hum Mol Genet. 2019 Jun 15;28(12):2062-2077. doi: 10.1093/hmg/ddz054.

Author Correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.  Slater HC1, Ross A2,3, Felger I3,4, Hofmann NE3,4, Robinson L5,6,7,8, Cook J9, Gonçalves BP10, Björkman A11, Ouedraogo AL12,13 et al.  Nat Commun. 2019 Jun 11;10(1):2644. doi: 10.1038/s41467-019-10790-0.

Dynamical analysis of bacteria in microscopy movies.  Vissers T1, Koumakis N1, Hermes M1,2, Brown AT1, Schwarz-Linek J1, Dawson A1, Poon WCK1.  PLoS One. 2019 Jun 6;14(6):e0217823. doi: 10.1371/journal.pone.0217823. eCollection 2019.

National, regional, and state-level burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in India: modelled estimates for 2000-15.  Wahl B1, Sharan A2, Deloria Knoll M3, Kumar R4, Liu L5, Chu Y6, McAllister DA7, Nair H8, Campbell H9, Rudan I9, Ram U10, Sauer M3, Shet A3, Black R6, Santosham M3, O'Brien KL3, Arora NK2.  Lancet Glob Health. 2019 Jun;7(6):e735-e747. doi: 10.1016/S2214-109X(19)30081-6.

A catalog of genetic loci associated with kidney function from analyses of a million individuals.  Wuttke M1,2, Li Y1, Li M3, Sieber KB4, Feitosa MF5, Gorski M6,7, Tin A8,9, Wang L5, Chu AY10, Hoppmann A1, Kirsten H11,12 et al.  Nat Genet. 2019 Jun;51(6):957-972. doi: 10.1038/s41588-019-0407-x. Epub 2019 May 31.

May 2019

PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa.  Abeler-Dörner L1, Grabowski MK2, Rambaut A3, Pillay D4,5, Fraser C1; PANGEA consortium.  Curr Opin HIV AIDS. 2019 May;14(3):173-180. doi: 10.1097/COH.0000000000000542.

Systematic scoping review protocol of methodologies of chronic respiratory disease surveys in low/middle-income countries.  Agarwal D1, Hanafi NS2, Chippagiri S3, Brakema EA4, Pinnock H5, Khoo EM2, Sheikh A5, Liew SM2, Ng CW2, Isaac R3, Chinna K2, Ping WL2, Hussein NB2, Juvekar S6; RESPIRE Collaborators.  NPJ Prim Care Respir Med. 2019 May 8;29(1):17. doi: 10.1038/s41533-019-0129-7.

Dynamics-dependent density distribution in active suspensions.  Arlt J1, Martinez VA2, Dawson A2, Pilizota T3, Poon WCK2.  Nat Commun. 2019 May 24;10(1):2321. doi: 10.1038/s41467-019-10283-0.

Cathelicidins and the Onset of Labour.  Boeckel SRV1, Hrabalkova L1, Baker TL2, MacPherson H1, Frew L1, Boyle AK1, McHugh BJ2, Wilson K1, Norman JE1, Dorin JR2, Davidson DJ2, Stock SJ3.  Sci Rep. 2019 May 14;9(1):7356. doi: 10.1038/s41598-019-43766-7.

Equine trypanosomosis: enigmas and diagnostic challenges.  Büscher P1, Gonzatti MI2, Hébert L3, Inoue N4, Pascucci I5, Schnaufer A6, Suganuma K4, Touratier L7, Van Reet N8.  Parasit Vectors. 2019 May 15;12(1):234. doi: 10.1186/s13071-019-3484-x.

NPR1 promotes its own and target gene expression in plant defense by recruiting CDK8.  Chen J1, Mohan R2, Zhang Y3, Li M1, Chen H1, Palmer IA1, Chang M1, Qi G1, Spoel SH4, Mengiste T5, Wang D6, Liu F7, Fu ZQ8.  Plant Physiol. 2019 May 20. pii: pp.00124.2019. doi: 10.1104/pp.19.00124. [Epub ahead of print]

Solid-phase synthesis of biocompatible N-heterocyclic carbene-Pd catalysts using a sub-monomer approach. Cherukaraveedu D1, Cowling PT1, Birch GP1, Bradley M1, Lilienkampf A1.  Org Biomol Chem. 2019 May 15. doi: 10.1039/c9ob00716d. [Epub ahead of print]

High fidelity fibre-based physiological sensing deep in tissue.  Choudhary TR1,2,3, Tanner MG2,4, Megia-Fernandez A5, Harrington K6, Wood HA6, Marshall A2, Zhu P5, Chankeshwara SV5, Choudhury D4 et al.  Sci Rep. 2019 May 22;9(1):7713. doi: 10.1038/s41598-019-44077-7.

Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group.  Crysnanto D1,2, Obbard DJ3,4.  BMC Evol Biol. 2019 May 8;19(1):99. doi: 10.1186/s12862-019-1425-0.

Ov2 is a modulator of OvHV-2 RTA mediated gene expression.  Dry I1, Nightingale K2,3, Ferguson J2,4, Hopkins J2, Dalziel R2.  Vet Res Commun. 2019 May;43(2):91-97. doi: 10.1007/s11259-019-09748-w. Epub 2019 Mar 21.

Staphylococcus aureus in Animals.  Haag AF1, Fitzgerald JR2, Penadés JR1.  Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.GPP3-0060-2019. 

Performance of the Psoroptes ovis antibody enzyme-linked immunosorbent assay in the face of low-level mite infestation.  Hamer K1, Burgess S2, Busin V3, Sargison ND4.  Vet Rec. 2019 May 24. pii: vetrec-2018-105304. doi: 10.1136/vr.105304. [Epub ahead of print]

Prevalence and Genetic Diversity of Toxoplasma gondii in Free-Ranging Chickens from the Caribbean.  Hamilton CM1,2, Robins R3, Thomas R4, Oura C5, Oliveira S6, Villena I7, Innes EA8, Katzer F8, Kelly PJ9.  Acta Parasitol. 2019 May 20. doi: 10.2478/s11686-019-00071-7. [Epub ahead of print]

Refugia and anthelmintic resistance: Concepts and challenges.  Hodgkinson JE1, Kaplan RM2, Kenyon F3, Morgan ER4, Park AW5, Paterson S6, Babayan SA7, Beesley NJ1, Britton C7, Chaudhry U8, Doyle SR9 et al.  Int J Parasitol Drugs Drug Resist. 2019 May 17;10:51-57. doi: 10.1016/j.ijpddr.2019.05.001. [Epub ahead of print]

Novel and conserved functions of S-nitrosoglutathione reductase (GSNOR) in tomato.  Hussain A1,2, Yun BW3, Kim JH4, Gupta KJ5, Hyung NI4, Loake GJ2.  J Exp Bot. 2019 May 14. pii: erz234. doi: 10.1093/jxb/erz234. [Epub ahead of print]

Association analyses identify 31 new risk loci for colorectal cancer susceptibility.  Law PJ1, Timofeeva M2, Fernandez-Rozadilla C3,4, Broderick P1, Studd J1, Fernandez-Tajes J5, Farrington S2, Svinti V2, Palles C6 et al.  Nat Commun. 2019 May 14;10(1):2154. doi: 10.1038/s41467-019-09775-w.

Survival costs of reproduction are mediated by parasite infection in wild Soay sheep.  Leivesley JA1, Bussière LF1, Pemberton JM2, Pilkington JG2,3, Wilson K4, Hayward AD1.  Ecol Lett. 2019 May 20. doi: 10.1111/ele.13275. [Epub ahead of print]

The association between hepatocellular carcinoma and direct-acting anti-viral treatment in patients with decompensated cirrhosis.  Mecci AJ1, Kemos P1, Leen C2, Lawson A3, Richardson P4, Khakoo SI5, Agarwal K6, Mutimer D7, Rosenberg WM8, Foster GR1, Irving WL9; HCV Research UK.  Aliment Pharmacol Ther. 2019 May 31. doi: 10.1111/apt.15296. [Epub ahead of print]

Regulation of Ov2 by virus encoded microRNAs.  Nightingale K1,2, Dry I1, Hopkins J1, Dalziel R3.  Vet Res Commun. 2019 May;43(2):99-104. doi: 10.1007/s11259-019-09749-9. Epub 2019 Mar 19.

Nitrate Reductase-Mediated Nitric Oxide Regulates the Leaf Shape in Arabidopsis by Mediating the Homeostasis of Reactive Oxygen Species.  Pan QN1,2, Geng CC3, Li DD4, Xu SW5, Mao DD6, Umbreen S7, Loake GJ8,9, Cui BM10,11.  Int J Mol Sci. 2019 May 7;20(9). pii: E2235. doi: 10.3390/ijms20092235.

Metabarcoding reveals a high diversity of woody host-associated Phytophthora spp. in soils at public gardens and amenity woodlands in Britain.  Riddell CE1, Frederickson-Matika D1, Armstrong AC1, Elliot M1,2, Forster J3, Hedley PE4, Morris J4, Thorpe P4,5, Cooke DE4, Pritchard L4, Sharp PM6, Green S1.  PeerJ. 2019 May 16;7:e6931. doi: 10.7717/peerj.6931. eCollection 2019.

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection.  Rigby RE1, Wise HM2,3, Smith N2, Digard P2, Rehwinkel J4.  Sci Rep. 2019 May 10;9(1):7216. doi: 10.1038/s41598-019-43632-6.

Advances in bronchiectasis.  Sapru K1, Hill AT2.  Clin Med (Lond). 2019 May;19(3):230-233. doi: 10.7861/clinmedicine.19-3-230.

Evolutionary sex allocation theory explains sex ratios in natural Plasmodium falciparum infections.  Schneider P1, Babiker HA2, Gadalla AAH3, Reece SE4.  Int J Parasitol. 2019 May 31. pii: S0020-7519(19)30133-X. doi: 10.1016/j.ijpara.2019.04.001. [Epub ahead of print]

Considering appropriate replication in the design of animal social network studies.  Smith LA1, Swain DL2, Innocent GT3, Nevison I3, Hutchings MR4.  Sci Rep. 2019 May 10;9(1):7208. doi: 10.1038/s41598-019-43764-9.

In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.  Sotillo J1,2, Pearson MS1, Becker L1, Mekonnen GG1, Amoah AS3, van Dam G3, Corstjens PLAM4, Murray J5, Mduluza T6,7, Mutapi F5,6, Loukas A1.  PLoS Negl Trop Dis. 2019 May 15;13(5):e0007362. doi: 10.1371/journal.pntd.0007362. [Epub ahead of print]

Signal Transduction in Systemic Immunity.  Spoel SH1.  Plant Cell. 2019 May 8. pii: tpc.00349.2019. doi: 10.1105/tpc.19.00349. [Epub ahead of print]

Survival and functional outcome of revision total knee arthroplasty with a total stabilizer knee system: minimum 5 years of follow-up.  Stevens JM1,2, Clement ND3, MacDonald D3, Hamilton DF4, Burnett R3.  Eur J Orthop Surg Traumatol. 2019 May 25. doi: 10.1007/s00590-019-02449-9. [Epub ahead of print]

Hepatitis B vaccination uptake in hard-to-reach populations in London: a cross-sectional study.  Taylor JEB1, Surey J1, MacLellan J1, Francis M1, Abubakar I2, Stagg HR1,3.  BMC Infect Dis. 2019 May 2;19(1):372. doi: 10.1186/s12879-019-3926-2.

Enhanced monocyte recruitment and delayed alternative macrophage polarisation accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice.  Toor IS1, Rückerl D2, Mair I3, Thomson A1, Rossi AG3, Newby DE1, Allen JE2, Gray GA1.  Clin Exp Immunol. 2019 May 23. doi: 10.1111/cei.13330. [Epub ahead of print]

The pathogenic actinobacterium Rhodococcus equi: What's in a name?  Vázquez-Boland JA1, Meijer WG2.  Mol Microbiol. 2019 May 17. doi: 10.1111/mmi.14267. [Epub ahead of print]

Musashi interaction with poly(A) binding protein is required for activation of target mRNA translation.  Cragle CE1, MacNicol MC2, Byrum SD1, Hardy LL2, Mackintosh SG1, Richardson WA3, Gray NK3, Childs GV2, Tackett AJ2, MacNicol AM4.  J Biol Chem. 2019 May 31. pii: jbc.RA119.007220. doi: 10.1074/jbc.RA119.007220. [Epub ahead of print]

Single-Cell Bacterial Electrophysiology Reveals Mechanisms of Stress-Induced Damage.  Krasnopeeva E1, Lo CJ2, Pilizota T3.  Biophys J. 2019 May 15. pii: S0006-3495(19)30392-3. doi: 10.1016/j.bpj.2019.04.039. [Epub ahead of print]

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.  Warrington NM1, Beaumont RN2, Horikoshi M3,4,5, Day FR6, Helgeland Ø7,8,9, Laurin C10,11, Bacelis J12, Peng S13,14, Hao K13,14 et al.  Nat Genet. 2019 May;51(5):804-814. doi: 10.1038/s41588-019-0403-1. Epub 2019 May 1.

Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.  González-Chávez Z1, Vázquez C1, Mejia-Tlachi M1, Márquez-Dueñas C2, Manning-Cela R2, Encalada R1, Rodríguez-Enríquez S1, Michels PAM3, Moreno-Sánchez R1, Saavedra E4.  Redox Biol. 2019 May 28;26:101231. doi: 10.1016/j.redox.2019.101231. [Epub ahead of print]

April 2019

Dose-dependent differential resistance of inbred chicken lines to avian pathogenic Escherichia coli challenge.  Alber A1, Costa T1, Chintoan-Uta C1, Bryson KJ1, Kaiser P1, Stevens MP1, Vervelde L1.  Avian Pathol. 2019 Apr;48(2):157-167. doi: 10.1080/03079457.2018.1562154. Epub 2019 Jan 14.

The fine-scale landscape of immunity and parasitism in a wild ungulate population.  Albery GF1, Becker DJ2, Kenyon F3, Nussey DH1, Pemberton JM1.  Integr Comp Biol. 2019 Apr 3. pii: icz016. doi: 10.1093/icb/icz016. [Epub ahead of print]

Detection of Neospora caninum DNA in cases of bovine and ovine abortion in the South-West of Scotland.  Bartley PM1, Guido S1, Mason C2, Stevenson H2, Chianini F1, Carty H3, Innes EA1, Katzer F1.  Parasitology. 2019 Apr 12:1-4. doi: 10.1017/S0031182019000301. [Epub ahead of print]

BEAST 2.5: An advanced software platform for Bayesian evolutionary analysis.  Bouckaert R1,2, Vaughan TG3,4, Barido-Sottani J3,4, Duchêne S5, Fourment M6, Gavryushkina A7, Heled J8, Jones G9, Kühnert D2, De Maio N10 et al.  PLoS Comput Biol. 2019 Apr 8;15(4):e1006650. doi: 10.1371/journal.pcbi.1006650. eCollection 2019 Apr.

African trypanosomes.  Cayla M1, Rojas F1, Silvester E1, Venter F1, Matthews KR2.  Parasit Vectors. 2019 Apr 29;12(1):190. doi: 10.1186/s13071-019-3355-5.

Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait.  Chundru VK1, Marioni RE2, Prendergast JGD2, Vallerga CL3, Lin T3, Berveridge AJ4, Consortium S3, Gratten J3, Hume DA2, Deary IJ2, Wray NR3, Visscher PM3, McRae AF3.  Genetics. 2019 Apr 30. pii: genetics.301861.2018. doi: 10.1534/genetics.118.301861. [Epub ahead of print].

Factors that influence confirmation of Neisseria gonorrhoeae positivity by molecular methods.  Cuschieri K1, Shepherd J2, Graham C3, Guerendiain D2, Templeton KE2.  J Clin Microbiol. 2019 Apr 3. pii: JCM.02068-18. doi: 10.1128/JCM.02068-18. [Epub ahead of print].

Tracking Staphylococcus aureus in ICU using Whole-Genome Sequencing.  Dancer SJ1, Adams CE2, Smith J3, Pichon B4, Kearns A4, Morrison D5.  J Hosp Infect. 2019 Apr 27. pii: S0195-6701(19)30185-9. doi: 10.1016/j.jhin.2019.04.016. [Epub ahead of print]

Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes.  Diack AB1, Boyle A1, Plinston C1, Hunt E1, Bishop MT1, Will RG1, Manson JC1.  Brain. 2019 Apr 1. pii: awz076. doi: 10.1093/brain/awz076. [Epub ahead of print]

Patienthood and participation in the digital era.  Erikainen S1, Pickersgill M1, Cunningham-Burley S1, Chan S1. Digit Health. 2019 Apr 23;5:2055207619845546. doi: 10.1177/2055207619845546. eCollection 2019 Jan-Dec.

PRRSV RNA detection in different matrices under typical storage conditions in the UK.  Fan J1,2, Gerber PF3, Cubas Atienzar A1, Eppink L1, Wang C4, Opriessnig T1,4.  Vet Rec. 2019 Apr 30. pii: vetrec-2018-105312. doi: 10.1136/vr.105312. [Epub ahead of print]

Disparity in endometriosis diagnoses between racial/ethnic groups.  Farland LV1, Horne AW2.  BJOG. 2019 Apr 29. doi: 10.1111/1471-0528.15805. [Epub ahead of print]

Radical polymerization inside living cells.  Geng J1, Li W1, Zhang Y1, Thottappillil N1, Clavadetscher J1, Lilienkampf A1, Bradley M2.  Nat Chem. 2019 Apr 15. doi: 10.1038/s41557-019-0240-y. [Epub ahead of print]

Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors.  Gong J1,2, Venkateswaran S1, Tanner MG3,2, Stone JM4,2, Bradley M1,2.  ACS Comb Sci. 2019 Apr 19. doi: 10.1021/acscombsci.9b00031. [Epub ahead of print]

Impacts of breed type and vaccination on Teladorsagia circumcincta infection in native sheep in Gran Canaria.  González JF1, Hernández JN2, Machín C2, Pérez-Hernández T2, Wright HW3, Corripio-Miyar Y3, Price DRG3, Matthews JB3, McNeilly TN3, Nisbet AJ3.  Vet Res. 2019 Apr 27;50(1):29. doi: 10.1186/s13567-019-0646-y.

The Challenge of Quantifying Synchrony in Malaria Parasites.  Greischar MA1, Reece SE2, Savill NJ2, Mideo N3.  Trends Parasitol. 2019 Apr 2. pii: S1471-4922(19)30053-4. doi: 10.1016/j.pt.2019.03.002. [Epub ahead of print]

Application of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infections.  Jayaraman S1, Harris C2, Paxton E1, Donachie AM3, Vaikkinen H3, McCulloch R3, Hall JPJ4 et al.  PLoS Negl Trop Dis. 2019 Apr 3;13(4):e0007262. doi: 10.1371/journal.pntd.0007262. [Epub ahead of print]

Lung Eosinophils - a Novel 'Virus Sink' that is Defective in Asthma?  Jesenak M1,2, Schwarze J3.  Allergy. 2019 Apr 10. doi: 10.1111/all.13811. [Epub ahead of print]

Higher Post-Operative Serum Vitamin D Level is Associated with Better Survival Outcome in Colorectal Cancer Patients.  Markotic A1,2, Langer S3, Kelava T2,4, Vucic K5, Turcic P6, Tokic T7, Stefancic L8, Radetic E7, Farrington S9, Timofeeva M9, Rudan I10, Campbell H10, Dunlop M9, Kirac I11, Zgaga L12.  Nutr Cancer. 2019 Apr 4:1-8. doi: 10.1080/01635581.2019.1597135. [Epub ahead of print]

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa.  McHugh BJ1, Wang R1, Li HN1, Beaumont PE1, Kells R1, Stevens H1, Young L1, Rossi AG1, Gray RD1, Dorin JR1, Gwyer Findlay EL1, Brough D2, Davidson DJ1.  PLoS Pathog. 2019 Apr 12;15(4):e1007694. doi: 10.1371/journal.ppat.1007694. [Epub ahead of print]

Bayesian inference of evolutionary histories under time-dependent substitution rates.  Membrebe JV1, Suchard MA2,3,4, Rambaut A5,6, Baele G1, Lemey P1.  Mol Biol Evol. 2019 Apr 19. pii: msz094. doi: 10.1093/molbev/msz094. [Epub ahead of print]

Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study.  Palmer T1, Wallace L2, Pollock KG3,4, Cuschieri K5, Robertson C3,6,7, Kavanagh K7, Cruickshank M8.  BMJ. 2019 Apr 3;365:l1161. doi: 10.1136/bmj.l1161.

α-Synuclein-Confocal Nanoscanning (ASYN-CONA), a Bead-Based Assay for Detecting Early-Stage α-Synuclein Aggregation.  Pérez-Pi I1, Evans DA1, Horrocks MH2,3, Pham NT1, Dolt KS4, Koszela J1, Kunath T4, Auer M1.  Anal Chem. 2019 Apr 18. doi: 10.1021/acs.analchem.8b03842. [Epub ahead of print]

Serogroup-specific meningococcal carriage by age group: a systematic review and meta-analysis.  Peterson ME1, Li Y1, Shanks H1, Mile R1, Nair H2, Kyaw MH3; Meningococcal Carriage Group.  BMJ Open. 2019 Apr 20;9(4):e024343. doi: 10.1136/bmjopen-2018-024343.

Evaluation of vaccine delivery systems for inducing long-lived antibody responses to Dermanyssus gallinae antigen in laying hens.  Price DRG1, Küster T2, Øines Ø3, Margaret Oliver E1, Bartley K1, Nunn F1, Barbero JFL4, Pritchard J2, Karp-Tatham E2, Hauge H3, Blake DP2, Tomley FM2, Nisbet AJ1.  Avian Pathol. 2019 Apr 29:1-44. doi: 10.1080/03079457.2019.1612514. [Epub ahead of print]

Extracellular RNA in viral-host interactions: Thinking outside the cell.  Ressel S1, Rosca A2, Gordon K1, Buck AH1.  Wiley Interdiscip Rev RNA. 2019 Apr 8:e1535. doi: 10.1002/wrna.1535. [Epub ahead of print]

Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice.  Sánchez-Quintero A1, Bradford BM1, Maizels R2, Donaldson DS1, Mabbott NA3.  Sci Rep. 2019 Apr 30;9(1):6674. doi: 10.1038/s41598-019-42900-9.

Mating barriers between genetically divergent strains of the parasitic nematode Haemonchus contortus suggest incipient speciation.  Sargison ND1, Redman E2, Morrison AA3, Bartley DJ3, Jackson F3, Hoberg E4, Gilleard JS5.  Int J Parasitol. 2019 Apr 26. pii: S0020-7519(19)30086-4. doi: 10.1016/j.ijpara.2019.02.008. [Epub ahead of print]

A high throughput deep amplicon sequencing method to show the emergence and spread of Calicophoron daubneyi rumen fluke infection in United Kingdom cattle herds.  Sargison ND1, Shahzad K2, Mazeri S1, Chaudhry U3.  Vet Parasitol. 2019 Apr;268:9-15. doi: 10.1016/j.vetpar.2019.02.007. Epub 2019 Mar 1.

International Forum on Occult hepatitis B infection and transfusion safety.  Seed CR, Allain JP, Lozano M, Laperche S1, Gallian P2, Gross S2, Kwon SY3, Oh EY3, Kim JN4, Chua SS5, Lam S5, Ang AL5 et al.  Vox Sang. 2019 Apr 10. doi: 10.1111/vox.12743. [Epub ahead of print]

Severe asthma: entering an era of new concepts and emerging therapies: Highlights of the 4th International Severe Asthma Forum, Madrid, 2018.  Seys SF1, Quirce S2, Agache I3, Akdis CA4, Alvaro-Lozano M5, Antolín-Amérigo D6, Bjermer L7, Bobolea I8, Bonini M9,10,11 et al.  Allergy. 2019 Apr 25. doi: 10.1111/all.13843. [Epub ahead of print]

The prevalence of methicillin-resistant Staphylococcus aureus among diabetic patients: a meta-analysis.  Stacey HJ1, Clements CS2, Welburn SC2,3, Jones JD4,5.  Acta Diabetol. 2019 Apr 6. doi: 10.1007/s00592-019-01301-0. [Epub ahead of print]

Improving engagement with healthcare in hepatitis C: a randomised controlled trial of a peer support intervention.  Stagg HR1,2, Surey J3, Francis M3, MacLellan J3, Foster GR4, Charlett A5, Abubakar I6.  BMC Med. 2019 Apr 1;17(1):71. doi: 10.1186/s12916-019-1300-2.

The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.  Svedberg FR1,2,3, Brown SL1, Krauss MZ4, Campbell L4, Sharpe C4, Clausen M5, Howell GJ1 et al.  Nat Immunol. 2019 Apr 1. doi: 10.1038/s41590-019-0352-y. [Epub ahead of print]

Phenotypic and molecular detection methods for carbapenemase-producing organisms and their clinical significance at two Scottish tertiary care hospitals.  Toner G1, Russell CD2,3,1, Hamilton F1, Templeton K1, Laurenson IF1.  J Med Microbiol. 2019 Apr;68(4):560-565. doi: 10.1099/jmm.0.000931. Epub 2019 Mar 14.

Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response.  Vaughan-Shaw PG1, Zgaga L2, Ooi LY1, Theodoratou E3,4, Timofeeva M1, Svinti V1, Walker M1, O'Sullivan F2, Ewing A1, Johnston S5, Din FVN1, Campbell H3, Farrington SM1, Dunlop MG1.  Gut. 2019 Apr 25. pii: gutjnl-2018-317922. doi: 10.1136/gutjnl-2018-317922. [Epub ahead of print]

Regulation of the Expression of DAPK1 by SUMO Pathway.  Wang Q1, Zhang X2, Chen L3, Weng S4, Xia Y5, Ye Y6, Li K7, Liao Z8, Chen P9, Alsamman K10, Meng C11, Stevens C12, Hupp TR13, Lin Y14.  Biomolecules. 2019 Apr 17;9(4). pii: E151. doi: 10.3390/biom9040151.

The evolutionary ecology of circadian rhythms in infection.  Westwood ML1, O'Donnell AJ2, de Bekker C3, Lively CM4, Zuk M5, Reece SE2.  Nat Ecol Evol. 2019 Apr;3(4):552-560. doi: 10.1038/s41559-019-0831-4. Epub 2019 Mar 18.

MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon response.  Witteveldt J1, Knol LI1, Macias S1.  Elife. 2019 Apr 23;8. pii: e44171. doi: 10.7554/eLife.44171. [Epub ahead of print]

Accuracy of genotyping for HPV16 and 18 to triage women with low-grade squamous intraepithelial lesions: a pooled analysis of VALGENT studies.  Xu L1, Benoy I2, Cuschieri K3, Poljak M4, Bonde J5, Arbyn M1.  Expert Rev Mol Diagn. 2019 Apr 29. doi: 10.1080/14737159.2019.1613890. [Epub ahead of print]

March 2019

Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes.  Acosta H1, Burchmore R2, Naula C2, Gualdrón-López M3, Quintero-Troconis E1, Cáceres AJ1, Michels PAM4, Concepción JL1, Quiñones W5.  Mol Biochem Parasitol. 2019 Mar 1;229:62-74. doi: 10.1016/j.molbiopara.2019.02.008. [Epub ahead of print]

Genetic differences in host infectivity affect disease spread and survival in epidemics.  Anacleto O1,2, Cabaleiro S3, Villanueva B4, Saura M4, Houston RD5, Woolliams JA5, Doeschl-Wilson AB5.  Sci Rep. 2019 Mar 20;9(1):4924. doi: 10.1038/s41598-019-40567-w.

Highlights of the mini-symposium on extracellular vesicles in inter-organismal communication, held in Munich, Germany, August 2018.  Bielska E1, Birch PRJ2, Buck AH3, Abreu-Goodger C4, Innes RW5, Jin H6, Pfaffl MW7, Robatzek S8, Regev-Rudzki N9, Tisserant C8, Wang S2, Weiberg A8.  J Extracell Vesicles. 2019 Mar 18;8(1):1590116. doi: 10.1080/20013078.2019.1590116. eCollection 2019.

Inflammation Resolution and the Induction of Granulocyte Apoptosis by Cyclin-Dependent Kinase Inhibitor Drugs.  Cartwright JA1,2, Lucas CD1, Rossi AG1.  Front Pharmacol. 2019 Feb 19;10:55. doi: 10.3389/fphar.2019.00055. eCollection 2019.

A pilot experience of common European infectious diseases curriculum for medical students: the IDEAL summer school.  Charlier C1,2,3, Wolf FI4, Vlieghe E5,6, Planquette B7, Damme PV8, Gaetano K9, Buffet P1, Henry B1, Cevik M10, Leen C10 et al.  Future Microbiol. 2019 Mar 22. doi: 10.2217/fmb-2019-0037. [Epub ahead of print]

Benefits of annual chemotherapeutic control of schistosomiasis on the development of protective immunity.  Chisango TJ1, Ndlovu B1, Vengesai A2, Nhidza AF1, Sibanda EP3, Zhou D4, Mutapi F5, Mduluza T6,7.  BMC Infect Dis. 2019 Mar 4;19(1):219. doi: 10.1186/s12879-019-3811-z.

Secretion of an Argonaute protein by a parasitic nematode and the evolution of its siRNA guides.  Chow FW1, Koutsovoulos G2, Ovando-Vázquez C3, Neophytou K1, Bermúdez-Barrientos JR3, Laetsch DR2, Robertson E1, Kumar S1, Claycomb JM4, Blaxter M2,5, Abreu-Goodger C3, Buck AH1,5.  Nucleic Acids Res. 2019 Mar 1. pii: gkz142. doi: 10.1093/nar/gkz142. [Epub ahead of print]

Human Papillomavirus Research: Where Should We Place Our Bets?  Cuschieri K1, Lorincz AT2, Nedjai B3.  Acta Cytol. 2019 Mar 28;63(2):1-12. doi: 10.1159/000493800. [Epub ahead of print]

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.  Dantoft W1, Robertson KA2, Watkins WJ3, Strobl B4, Ghazal P1,2.  Front Microbiol. 2019 Mar 4;10:355. doi: 10.3389/fmicb.2019.00355. eCollection 2019.

Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control.  Davidson L1, Francis L1, Cordiner RA2, Eaton JD1, Estell C1, Macias S2, Cáceres JF2, West S3.  Cell Rep. 2019 Mar 5;26(10):2779-2791.e5. doi: 10.1016/j.celrep.2019.02.012.

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.  Doyle SR1, Illingworth CJR2,3, Laing R4, Bartley DJ5, Redman E6, Martinelli A7,8,9, Holroyd N7, Morrison AA5, Rezansoff A6, Tracey A7, Devaney E4, Berriman M7, Sargison N10, Cotton JA11, Gilleard JS12.  BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6.

Ov2 is a modulator of OvHV-2 RTA mediated gene expression.  Dry I1, Nightingale K2,3, Ferguson J2,4, Hopkins J2, Dalziel R2.  Vet Res Commun. 2019 Mar 21. doi: 10.1007/s11259-019-09748-w. [Epub ahead of print]

Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus.  Everett HE1, Aramouni M2, Coward V3, Ramsay A3, Kelly M3, Morgan S4, Tchilian E4, Canini L5, Woolhouse MEJ5, Gilbert S2, Charleston B4, Brown IH3, Brookes SM3.  Vaccine. 2019 Mar 23. pii: S0264-410X(19)30316-0. doi: 10.1016/j.vaccine.2019.02.078. [Epub ahead of print]

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.  Fleskens V1, Minutti CM2, Wu X3, Wei P4, Pals CEGM5, McCrae J2, Hemmers S6, Groenewold V7, Vos HJ8, Rudensky A6, Pan F9, Li H10, Zaiss DM11, Coffer PJ12.  Cell Rep. 2019 Mar 26;26(13):3600-3612.e6. doi: 10.1016/j.celrep.2019.02.087.

Comparison of Unyvero P55 Pneumonia Cartridge, in-house PCR and culture for the identification of respiratory pathogens and antibiotic resistance in bronchoalveolar lavage fluids in the critical care setting.  Gadsby NJ1, McHugh MP2, Forbes C3,4, MacKenzie L2, Hamilton SKD3,5, Griffith DM3,6, Templeton KE2.  Eur J Clin Microbiol Infect Dis. 2019 Mar 11. doi: 10.1007/s10096-019-03526-x. [Epub ahead of print]

Comparative virulence of Caribbean, Brazilian and European isolates of Toxoplasma gondii.  Hamilton CM1, Black L2, Oliveira S3, Burrells A2, Bartley PM2, Melo RPB4, Chianini F2, Palarea-Albaladejo J5, Innes EA2, Kelly PJ6, Katzer F2.  Parasit Vectors. 2019 Mar 14;12(1):104. doi: 10.1186/s13071-019-3372-4.

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo.  Harris AJ1, Mirchandani AS1, Lynch RW1, Murphy F1, Delaney L1, Small D2, Coelho P1, Watts ER1, Sadiku P1, Griffith D3, Dickinson RS1 et al.  Am J Respir Crit Care Med. 2019 Mar 8. doi: 10.1164/rccm.201808-1599OC. [Epub ahead of print]

Genome-wide methylation is modified by caloric restriction in Daphnia magna.  Hearn J1,2, Pearson M3, Blaxter M3, Wilson PJ4, Little TJ3.  BMC Genomics. 2019 Mar 8;20(1):197. doi: 10.1186/s12864-019-5578-4. 

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage.  Hendriksen RS1, Munk P1, Njage P1, van Bunnik B2, McNally L3, Lukjancenko O1, Röder T1, Nieuwenhuijse D4, Pedersen SK1, Kjeldgaard J1 et al.  Nat Commun. 2019 Mar 8;10(1):1124. doi: 10.1038/s41467-019-08853-3.

The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK.  Hooper KM1, Casanova V1, Kemp S1, Staines KA1, Satsangi J2,3, Barlow PG1, Henderson P4,5, Stevens C1.  Inflamm Bowel Dis. 2019 Mar 19. pii: izz039. doi: 10.1093/ibd/izz039. [Epub ahead of print]

SANTA-SIM: simulating viral sequence evolution dynamics under selection and recombination.  Jariani A1,2, Warth C3, Deforche K4, Libin P5,6, Drummond AJ7,8, Rambaut A9, Matsen Iv FA3, Theys K5.  Virus Evol. 2019 Mar 8;5(1):vez003. doi: 10.1093/ve/vez003. eCollection 2019 Jan.

A soft 3D polyacrylate hydrogel recapitulates the cartilage niche and allows growth-factor free tissue engineering of human articular cartilage.  Jiménez G1, Venkateswaran S2, López-Ruiz E3, Perán M4, Pernagallo S5, Díaz-Monchón JJ6, Canadas RF7, Antich C1, Oliveira JM8 et al.  Acta Biomater. 2019 Mar 22. pii: S1742-7061(19)30215-6. doi: 10.1016/j.actbio.2019.03.040. [Epub ahead of print]

Assessment of the start-up process of anaerobic digestion utilizing swine manure: 13C fractionation of biogas and microbial dynamics.  Lv Z1,2, Liang J3,4, Chen X3,4, Chen Z5, Jiang J3,4, Loake GJ6,7.  Environ Sci Pollut Res Int. 2019 Mar 21. doi: 10.1007/s11356-019-04703-3. [Epub ahead of print]

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity.  Łyszkiewicz M1,2, Winter SJ3, Witzlau K1, Föhse L1, Brownlie R4, Puchałka J5, Verheyden NA3 et al.  PLoS Biol. 2019 Mar 11;17(3):e2006716. doi: 10.1371/journal.pbio.2006716. eCollection 2019 Mar.

Bacterial and viral respiratory tract microbiota and host characteristics in children with lower respiratory tract infections: a matched case-control study.  Man WH1, van Houten MA2, Mérelle ME3, Vlieger AM4, Chu MLJN5, Jansen NJG6, Sanders EAM5, Bogaert D7.  Lancet Respir Med. 2019 Mar 15. pii: S2213-2600(18)30449-1. doi: 10.1016/S2213-2600(18)30449-1. [Epub ahead of print]

A novel, high-welfare methodology for evaluating poultry red mite interventions in vivo.  Nunn F1, Bartley K2, Palarea-Albaladejo J3, Innocent GT4, Turnbull F5, Wright HW6, Nisbet AJ7.  Vet Parasitol. 2019 Mar;267:42-46. doi: 10.1016/j.vetpar.2019.01.011. Epub 2019 Feb 12.

Access, accountability, and the proliferation of psychological therapy: On the introduction of the IAPT initiative and the transformation of mental healthcare.  Pickersgill M1.  Soc Stud Sci. 2019 Mar 25:306312719834070. doi: 10.1177/0306312719834070. [Epub ahead of print]

When to kill a cull: factors affecting the success of culling wildlife for disease control.  Prentice JC1,2,3, Fox NJ1, Hutchings MR1, White PCL4, Davidson RS1, Marion G2.  J R Soc Interface. 2019 Mar 29;16(152):20180901. doi: 10.1098/rsif.2018.0901. 

Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis.  Ratmann O1,2, Grabowski MK3,4, Hall M5, Golubchik T5, Wymant C6,5, Abeler-Dörner L5, Bonsall D5, Hoppe A7 et al.  Nat Commun. 2019 Mar 29;10(1):1411. doi: 10.1038/s41467-019-09139-4.

Hypoxia and the regulation of myeloid cell metabolic imprinting: consequences for the inflammatory response.  Sadiku P1, Walmsley SR2.  EMBO Rep. 2019 Mar 14. pii: e47388. doi: 10.15252/embr.201847388. [Epub ahead of print]

The Etiological Role of Common Respiratory Viruses in Acute Respiratory Infections in Older Adults: A Systematic Review and Meta-analysis.  Shi T1, Arnott A1, Semogas I1, Falsey AR2,3, Openshaw P4, Wedzicha JA4, Campbell H1, Nair H1,3; RESCEU Investigators.  J Infect Dis. 2019 Mar 8. pii: jiy662. doi: 10.1093/infdis/jiy662. [Epub ahead of print]

Global Disease Burden Estimates of Respiratory Syncytial Virus-Associated Acute Respiratory Infection in Older Adults in 2015: A Systematic Review and Meta-Analysis.  Shi T1, Denouel A2, Tietjen AK1, Campbell I1, Moran E1, Li X1, Campbell H1, Demont C2, Nyawanda BO3, Chu HY4, Stoszek SK5, Krishnan A6, Openshaw P7, Falsey AR8,9, Nair H1,9; RESCEU Investigators.  J Infect Dis. 2019 Mar 18. pii: jiz059. doi: 10.1093/infdis/jiz059. [Epub ahead of print]

Global and Regional Burden of Hospital Admissions for Pneumonia in Older Adults: A Systematic Review and Meta-Analysis.  Shi T1, Denouel A2, Tietjen AK1, Lee JW1, Falsey AR3,4, Demont C2, Nyawanda BO5, Cai B6, Fuentes R7, Stoszek SK8, Openshaw P9, Campbell H1, Nair H1,4; RESCEU Investigators.  J Infect Dis. 2019 Mar 8. pii: jiz053. doi: 10.1093/infdis/jiz053. [Epub ahead of print]

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.  Slater HC1, Ross A2,3, Felger I3,4, Hofmann NE3,4, Robinson L5,6,7,8, Cook J9, Gonçalves BP10, Björkman A11 et al.  Nat Commun. 2019 Mar 29;10(1):1433. doi: 10.1038/s41467-019-09441-1.

BSE infectivity survives burial for five years with only limited spread.  Somerville RA1, Fernie K1, Smith A1, Bishop K2, Maddison BC2, Gough KC3, Hunter N4.  Arch Virol. 2019 Apr;164(4):1135-1145. doi: 10.1007/s00705-019-04154-8. Epub 2019 Feb 24.

Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor.  Sun CQ1, Arnold RS1, Hsieh CL2, Dorin JR3, Lian F4, Li Z5, Petros JA1,6.  Cancer Biol Ther. 2019 Mar 22:1-13. doi: 10.1080/15384047.2018.1564564. [Epub ahead of print]

Phenotypic and molecular detection methods for carbapenemase-producing organisms and their clinical significance at two Scottish tertiary care hospitals.  Toner G1, Russell CD2,1,3, Hamilton F1, Templeton K1, Laurenson IF1.  J Med Microbiol. 2019 Mar 14. doi: 10.1099/jmm.0.000931. [Epub ahead of print]

Sulphur: the heart of nitric oxide-dependent redox signalling.  Umbreen S1, Lubega J1, Loake GJ1.  J Exp Bot. 2019 Mar 26. pii: erz135. doi: 10.1093/jxb/erz135. [Epub ahead of print]

Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.  Urdaneta EC1, Vieira-Vieira CH2, Hick T1, Wessels HH3,4, Figini D1, Moschall R5, Medenbach J5, Ohler U3,4, Granneman S6, Selbach M2, Beckmann BM7.  Nat Commun. 2019 Mar 1;10(1):990. doi: 10.1038/s41467-019-08942-3.

Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts.  van der Heijden M1, Miedema DM1, Waclaw B2, Veenstra VL1, Lecca MC1, Nijman LE1, van Dijk E3, van Neerven SM1, Lodestijn SC1 et al.  Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6140-6145. doi: 10.1073/pnas.1813417116. Epub 2019 Mar 8.

Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals.  Wan X1,2, Volpetti F3, Petrova E3, French C1,2, Maerkl SJ3, Wang B4,5.  Nat Chem Biol. 2019 Mar 25. doi: 10.1038/s41589-019-0244-3. [Epub ahead of print]

Crosstalk Between Mammalian Antiviral Pathways.  Watson SF1, Knol LI2, Witteveldt J3, Macias S4.  Noncoding RNA. 2019 Mar 22;5(1). pii: E29. doi: 10.3390/ncrna5010029.

Simultaneous detection of five pig viruses associated with enteric disease in pigs using EvaGreen real-time PCR combined with melting curve analysis.  Wen D1, Liu G1, Opriessnig T2, Yang Z1, Jiang Y3.  J Virol Methods. 2019 Mar 4;268:1-8. doi: 10.1016/j.jviromet.2019.03.001. [Epub ahead of print]

Immune and non-immune mediated roles of regulatory T-cells during wound healing.  Zaiss DM1, Minutti CM1,2, Knipper JA1.  Immunology. 2019 Mar 13. doi: 10.1111/imm.13057. [Epub ahead of print]

Antibodies to Peptides in Semiconserved Domains of RIFINs and STEVORs Correlate with Malaria Exposure.  Zhou AE1, Berry AA1, Bailey JA2, Pike A1, Dara A3, Agrawal S1, Stucke EM1, Ouattara A1, Coulibaly D3, Lyke KE1 et al.  mSphere. 2019 Mar 20;4(2). pii: e00097-19. doi: 10.1128/mSphere.00097-19.

February 2019

Establishing a hepatitis C continuum of care among HIV/hepatitis C virus-coinfected individuals in EuroSIDA.  Amele S1, Peters L2, Sluzhynska M3, Yakovlev A4, Scherrer A5, Domingo P6, Gerstoft J7, Viard JP8, Gisinger M9, Flisiak R10, Bhaghani S11, Ristola M12, Leen C13 et al.  HIV Med. 2019 Feb 8. doi: 10.1111/hiv.12711. [Epub ahead of print]

Investigating the epidemiology of medication errors in adults in community care settings. A retrospective cohort study in central Saudi Arabia.  Assiri GA1, Alkhenizan AH, Al-Khani SA, Grant LM, Sheikh A.  Saudi Med J. 2019 Feb;40(2):158-167. doi: 10.15537/smj.2019.2.23933.

Global burden of Clostridium difficile infections: a systematic review and meta-analysis.  Balsells E1,2, Shi T1,2, Leese C1, Lyell I1, Burrows J1, Wiuff C3, Campbell H1, Kyaw MH4,5, Nair H1,5.  J Glob Health. 2019 Jun;9(1):010407. doi: 10.7189/jogh.09.010407.

ILC2 Orchestration of Local Immune Function in Adipose Tissue.  Bénézech C1, Jackson-Jones LH2.  Front Immunol. 2019 Feb 7;10:171. doi: 10.3389/fimmu.2019.00171. eCollection 2019.

CD4 receptor diversity in chimpanzees protects against SIV infection.  Bibollet-Ruche F1, Russell RM1,2, Liu W1, Stewart-Jones GBE3, Sherrill-Mix S1,2, Li Y1, Learn GH1, Smith AG1, Gondim MVP1, Plenderleith LJ4,5 et al.  Proc Natl Acad Sci U S A. 2019 Feb 4. pii: 201821197. doi: 10.1073/pnas.1821197116. [Epub ahead of print]

The Long Pentraxin PTX3 Is of Major Importance Among Acute Phase Proteins in Chickens.  Burkhardt NB1, Röll S1, Staudt A1, Elleder D2, Härtle S1, Costa T3, Alber A3, Stevens MP3, Vervelde L3, Schusser B4, Kaspers B1.  Front Immunol. 2019 Feb 1;10:124. doi: 10.3389/fimmu.2019.00124. eCollection 2019.

Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection.  Chiweshe SM1, Steketee PC1, Jayaraman S1, Paxton E1, Neophytou K2, Erasmus H3, Labuschagne M3, Cooper A4, MacLeod A4, Grey FE1, Morrison LJ1.  PLoS Negl Trop Dis. 2019 Feb 19;13(2):e0007189. doi: 10.1371/journal.pntd.0007189. [Epub ahead of print]

Lack of concordance between ECDC and CDC systems for surveillance of ventilator associated pneumonia.  Craven TH1,2,3, Wojcik G4, McCoubrey J5, Brooks O6, Grant E7, Reilly J5, Laurenson IF6, Kefala K8,4,6, Walsh TS8,4,6.  Intensive Care Med. 2018 Feb;44(2):265-266. doi: 10.1007/s00134-017-4993-8. Epub 2017 Nov 20.

Type I interferon induces CXCL13 to support ectopic germinal center formation.  Denton AE1, Innocentin S2, Carr EJ2,3, Bradford BM4, Lafouresse F5,6, Mabbott NA4, Mörbe U7, Ludewig B7, Groom JR5,6, Good-Jacobson KL8,9, Linterman MA10.  J Exp Med. 2019 Feb 5. pii: jem.20181216. doi: 10.1084/jem.20181216. [Epub ahead of print]

Characterisation of major histocompatibility complex class IIa haplotypes in an island sheep population.  Dicks KL1, Pemberton JM2, Ballingall KT3.  Immunogenetics. 2019 Feb 22. doi: 10.1007/s00251-019-01109-w. [Epub ahead of print].

A Magnesium Transport Protein Related to Mammalian SLC41 and Bacterial MgtE Contributes to Circadian Timekeeping in a Unicellular Green Alga.  Feord HK1, Dear FEG2, Obbard DJ3, van Ooijen G4.  Genes (Basel). 2019 Feb 19;10(2). pii: E158. doi: 10.3390/genes10020158.

Intra- and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test: Results from an international study.  Floore A1, Hesselink A1, Oštrbenk A2, Alcaniz E3, Rothe B4, Pedersen H5, Torres Hortal M6, Doorn S1, Quint W7, Petry KU4, Poljak M2, Cuschieri K3, Bonde J5, de Sanjosé S6, Bleeker M8, Heideman D8.  J Clin Lab Anal. 2019 Feb 13:e22854. doi: 10.1002/jcla.22854. [Epub ahead of print]

Absence of hantavirus in water voles and Eurasian beavers in Britain.  Girling SJ1, McElhinney LM2, Fraser MA3, Gow D4, Pizzi R1, Naylor A1, Cole G1, Brown D1, Rosell F5, Schwab G6, Campbell-Palmer R7.  Vet Rec. 2019 Feb 23;184(8):253. doi: 10.1136/vr.105246.

Composite Fasciola hepatica faecal egg sedimentation test for cattle.  Graham-Brown J1, Williams DJL1, Skuce P2, Zadoks RN2,3, Dawes S2, Swales H4, Van Dijk J5.  Vet Rec. 2019 Feb 2. pii: vetrec-2018-105128. doi: 10.1136/vr.105128. [Epub ahead of print]

Use of Isotopically Labelled Substrates Reveals Kinetic Differences Between Human and Bacterial Serine Palmitoyltransferase.  Harrison PJ1, Gable K2, Somashekarappa N2, Kelly V1, Clarke DJ1, Dunn TM2, Campopiano DJ3.  J Lipid Res. 2019 Feb 21. pii: jlr.M089367. doi: 10.1194/jlr.M089367. [Epub ahead of print]

The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex 'mix-and-match' implementation package.  Hays JP1, Mitsakakis K2, Luz S3, van Belkum A4, Becker K5, van den Bruel A6, Harbarth S7, Rex JH8, Simonsen GS9, Werner G10, Di Gregori V11,12, Lüdke G13 et al.  Eur J Clin Microbiol Infect Dis. 2019 Feb 2. doi: 10.1007/s10096-019-03492-4. [Epub ahead of print]

IL-33 in the developing lung - roles in asthma and infection.  Johansson K1,2, McSorley HJ3.  Pediatr Allergy Immunol. 2019 Feb 7. doi: 10.1111/pai.13040. [Epub ahead of print]

Disentangling the genetics of lean mass.  Karasik D1,2, Zillikens MC3,4, Hsu YH1,5,6, Aghdassi A7, Akesson K8,9, Amin N10, Barroso I11,12,13, Bennett DA14, Bertram L15, Bochud M16 et al.  Am J Clin Nutr. 2019 Feb 1;109(2):276-287. doi: 10.1093/ajcn/nqy272.

Effects of various feedstocks on isotope fractionation of biogas and microbial community structure during anaerobic digestion.   Lv Z1, Chen Z2, Chen X3, Liang J3, Jiang J3, Loake GJ4.  Waste Manag. 2019 Feb 1;84:211-219. doi: 10.1016/j.wasman.2018.11.043. Epub 2018 Dec 4.

Making sense of bodily sensations: Do shared cancer narratives influence symptom appraisal?  Macdonald S1, Conway E2, Bikker A3, Browne S2, Robb K2, Campbell C3, Steele RJ4, Weller D3, Macleod U5.  Soc Sci Med. 2019 Feb;223:31-39. doi: 10.1016/j.socscimed.2018.12.034. Epub 2019 Jan 10.

Thioredoxin-mediated redox signalling in plant immunity.  Mata-Pérez C1, Spoel SH2.  Plant Sci. 2019 Feb;279:27-33. doi: 10.1016/j.plantsci.2018.05.001. Epub 2018 May 4.

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.  Minutti CM1, Modak RV2, Macdonald F2, Li F3, Smyth DJ4, Dorward DA5, Blair N2, Husovsky C2, Muir A2, Giampazolias E6, Dobie R7, Maizels RM4 et al.  Immunity. 2019 Feb 6. pii: S1074-7613(19)30031-7. doi: 10.1016/j.immuni.2019.01.008. [Epub ahead of print]

Molecular identification of bovine trypanosomes in relation to cattle sources in southwest Nigeria.  Odeniran PO1, Macleod ET2, Ademola IO3, Welburn SC4.  Parasitol Int. 2019 Feb;68(1):1-8. doi: 10.1016/j.parint.2018.09.005. Epub 2018 Sep 20.

Endosymbionts interaction with trypanosomes in Palpalis group of Glossina captured in southwest Nigeria.  Odeniran PO1, Macleod ET2, Ademola IO3, Welburn SC4.  Parasitol Int. 2019 Feb 1;70:64-69. doi: 10.1016/j.parint.2019.01.011. [Epub ahead of print]

Molecular identification of bloodmeal sources and trypanosomes in Glossina spp., Tabanus spp. and Stomoxys spp. trapped on cattle farm settlements in southwest Nigeria.  Odeniran PO1,2, Macleod ET2, Ademola IO1, Welburn SC2,3.  Med Vet Entomol. 2019 Feb 7. doi: 10.1111/mve.12358. [Epub ahead of print]

A core transcriptional signature of human microglia: Derivation and utility in describing region-dependent alterations associated with Alzheimer's disease.  Patir A1, Shih B1, McColl BW1,2, Freeman TC1.  Glia. 2019 Feb 13. doi: 10.1002/glia.23572. [Epub ahead of print]

Meningococcal serogroups and surveillance: a systematic review and survey.  Peterson ME1, Li Y1, Bita A2, Moureau A3, Nair H1,4,5, Kyaw MH6,5; Meningococcal Surveillance Group (in alphabetical order), Abad R7, Bailey F8, Garcia IF9, Decheva A10, Krizova P11, Melillo T12, Skoczynska A13, Vladimirova N10.  J Glob Health. 2019 Jun;9(1):010409. doi: 10.7189/jogh.09.010409.

Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization.  Rylance J1, de Steenhuijsen Piters WAA2, Mina MJ3, Bogaert D4, French N5, Ferreira DM6; and the EHPC-LAIV study group.  Am J Respir Crit Care Med. 2019 Feb 13. doi: 10.1164/rccm.201811-2081LE. [Epub ahead of print]

Chromosome-Wide Evolution and Sex Determination in the Three-Sexed Nematode Auanema rhodensis.  Tandonnet S1, Koutsovoulos GD2, Adams S1, Cloarec D1, Parihar M1, Blaxter ML2, Pires-daSilva A3.  G3 (Bethesda). 2019 Feb 15. pii: g3.0011.2019. doi: 10.1534/g3.119.0011. [Epub ahead of print]

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury.  Zheng X1, Zhang A1, Binnie M2, McGuire K2, Webster SP2, Hughes J1, Howie SEM1, Mole DJ3.  Exp Mol Med. 2019 Feb 13;51(2):15. doi: 10.1038/s12276-019-0210-x.

Investigation of relationship between vitamin D status and reproductive fitness in Scottish hill sheep.  Zhou P1,2, McEvoy TG2, Gill AC1,3, Lambe NR2, Morgan-Davies CR2, Hurst E1, Sargison ND1, Mellanby RJ4.  Sci Rep. 2019 Feb 4;9(1):1162. doi: 10.1038/s41598-018-37843-6.

January 2019

Emergence and the spread of the F200Y benzimidazole resistance mutation in Haemonchus contortus and Haemonchus placei from buffalo and cattle.  Ali Q1, Rashid I1, Shabbir MZ2, Aziz-Ul-Rahman2, Shahzad K3, Ashraf K1, Sargison ND4, Chaudhry U5.  Vet Parasitol. 2019 Jan;265:48-54. doi: 10.1016/j.vetpar.2018.12.001. Epub 2018 Dec 11.

Global burden of Clostridium difficile infections: a systematic review and meta-analysis.  Balsells E1,2, Shi T1,2, Leese C1, Lyell I1, Burrows J1, Wiuff C3, Campbell H1, Kyaw MH4,5, Nair H1,5.  J Glob Health. 2019 Jun;9(1):010407. doi: 10.7189/jogh.09.010407.

Rabbit haemorrhagic disease virus type 2 in hares in England.  Bell DJ1, Davis JP1, Gardner M1, Barlow AM2, Rocchi M3, Gentil M4, Wilson RJ5.  Vet Rec. 2019 Jan 26;184(4):127-128. doi: 10.1136/vr.l337.

Production and Application of Stable Isotope-Labeled Internal Standards for RNA Modification Analysis.  Borland K1, Diesend J2, Ito-Kureha T3, Heissmeyer V4,5, Hammann C6, Buck AH7, Michalakis S8, Kellner S9.  Genes (Basel). 2019 Jan 5;10(1). pii: E26. doi: 10.3390/genes10010026.

Baseline HPV prevalence in rectal swabs from men attending a sexual health clinic in Scotland: assessing the potential impact of a selective HPV vaccination programme for men who have sex with men.  Cameron RL1, Cuschieri K2, Pollock KGJ3.  Sex Transm Infect. 2019 Jan 13. pii: sextrans-2018-053668. doi: 10.1136/sextrans-2018-053668. [Epub ahead of print]

Living with and beyond cancer with comorbid illness: a qualitative systematic review and evidence synthesis.  Cavers D1, Habets L2, Cunningham-Burley S3, Watson E4, Banks E5, Campbell C6.  J Cancer Surviv. 2019 Jan 26. doi: 10.1007/s11764-019-0734-z. [Epub ahead of print]

Macrophages from Susceptible and Resistant Chicken Lines have Different Transcriptomes following Marek's Disease Virus Infection.  Chakraborty P1,2, Kuo R3, Vervelde L4, Dutia BM5, Kaiser P1, Smith J6.  Genes (Basel). 2019 Jan 22;10(2). pii: E74. doi: 10.3390/genes10020074.

Ensuring quality in cervical screening programmes based on molecular HPV testing.  Cuschieri K1, Schuurman R2, Coughlan S3.  Cytopathology. 2019 Jan 18. doi: 10.1111/cyt.12679. [Epub ahead of print]

Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity.  Emmott E1, de Rougemont A2, Hosmillo M1, Lu J1, Fitzmaurice TJ3, Haas J4, Goodfellow I1.Emmott E1, de Rougemont A2, Hosmillo M1, Lu J1, Fitzmaurice TJ3, Haas J4, Goodfellow I1.  J Biol Chem. 2019 Jan 15. pii: jbc.RA118.006780. doi: 10.1074/jbc.RA118.006780. [Epub ahead of print]

The anthelmintic drug Praziquantel promotes human Tr1 differentiation.  Eyoh E1, McCallum P1, Killick J2, Amanfo S1, Mutapi F1,3, Astier AL2,4.  Immunol Cell Biol. 2019 Jan 8. doi: 10.1111/imcb.12229. [Epub ahead of print]

Measurement of serum macrophage migration inhibitory factor (MIF) and correlation with severity and pruritus scores in client owned dogs with atopic dermatitis.  Gow DJ1, Jackson H2, Forsythe P2, Gow AG1, Mellanby RJ1, Hume DA1,3, Nuttall T1.  Vet Dermatol. 2019 Jan 23. doi: 10.1111/vde.12721. [Epub ahead of print]

Spread and impact of goat pox ("sagolay bohonta") in a village smallholder community around Kaziranga National Park, Assam, India.  Hopker A1, Pandey N2, Saikia D2, Goswami J2, Hopker S3, Saikia R2, Sargison N3.  Trop Anim Health Prod. 2019 Jan 16. doi: 10.1007/s11250-018-1759-4. [Epub ahead of print]

Characterization of Subpopulations of Chicken Mononuclear Phagocytes That Express TIM4 and CSF1R.  Hu T1, Wu Z1, Bush SJ1, Freem L1, Vervelde L1, Summers KM1,2, Hume DA3,2, Balic A3, Kaiser P1.  J Immunol. 2019 Jan 9. pii: ji1800504. doi: 10.4049/jimmunol.1800504. [Epub ahead of print]

The cellular localization of avian influenza virus PB1-F2 protein alters the magnitude of IFN2 promoter and NFκB-dependent promoter antagonism in chicken cells.  James J1,2,3, Smith N4, Ross C5, Iqbal M3, Goodbourn S5, Digard P4, Barclay WS2, Shelton H3.  J Gen Virol. 2019 Jan 23. doi: 10.1099/jgv.0.001220. [Epub ahead of print]

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.  Karlsson Linnér R1,2,3, Biroli P4, Kong E5, Meddens SFW6,7,8, Wedow R9,10,11,12, Fontana MA13,14, Lebreton M15,16, Tino SP17, Abdellaoui A18 et al.  Nat Genet. 2019 Jan 14. doi: 10.1038/s41588-018-0309-3. [Epub ahead of print]

Advances in measuring influenza burden of disease.  Lee VJ1,2, Ho ZJM1, Goh EH1, Campbell H3, Cohen C4,5, Cozza V6, Fitzner J6, Jara J7, Krishnan A8, Bresee J9; WHO Working Group on Influenza Burden of Disease.  Influenza Other Respir Viruses. 2018 Jan;12(1):3-9. doi: 10.1111/irv.12533. 

Detecting the True Extent of Introgression during Anthropogenic Hybridization.  McFarlane SE1, Pemberton JM2.  Trends Ecol Evol. 2019 Jan 14. pii: S0169-5347(18)30305-7. doi: 10.1016/j.tree.2018.12.013. [Epub ahead of print]

Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis.  Mouton AJ1, Ma Y1, Rivera Gonzalez OJ1, Daseke MJ 2nd1, Flynn ER1, Freeman TC2, Garrett MR3, DeLeon-Pennell KY1,4, Lindsey ML5,6.  Basic Res Cardiol. 2019 Jan 11;114(2):6. doi: 10.1007/s00395-019-0715-4.

Increased risk of HPV-associated genital cancers in men and women as a consequence of pre-invasive disease.  Pan J1, Kavanagh K1,2, Cuschieri K3, Pollock KG4,5, Gilbert DC6, Millan D7, Bell S7, Graham SV8, Williams ARW9, Cruickshank ME10, Palmer T9, Wakeham K11,6.  Int J Cancer. 2019 Jan 16. doi: 10.1002/ijc.32126. [Epub ahead of print]

Meningococcal serogroups and surveillance: a systematic review and survey.  Peterson ME1, Li Y1, Bita A2, Moureau A3, Nair H1,4,5, Kyaw MH6,5; Meningococcal Surveillance Group (in alphabetical order), Abad R7, Bailey F8, Garcia IF9, Decheva A10, Krizova P11, Melillo T12, Skoczynska A13, Vladimirova N10.  J Glob Health. 2019 Jun;9(1):010409. doi: 10.7189/jogh.09.010409.

Adaptive Evolution of RH5 in Ape Plasmodium species of the Laverania Subgenus.  Plenderleith LJ1,2, Liu W3, MacLean OA1,2, Li Y3, Loy DE3,4, Sundararaman SA3,4, Bibollet-Ruche F3, Learn GH3, Hahn BH3,4, Sharp PM5,2.  MBio. 2018 Jan 23;9(1). pii: e02237-17. doi: 10.1128/mBio.02237-17.

Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia.  Preston JA1, Bewley MA1, Marriott HM1, Houghton AM2, Mohasin M3, Jubrail J1, Morris L1, Stephenson YL1, Cross S1,4, Greaves DR5 et al.  Am J Respir Crit Care Med. 2019 Jan 16. doi: 10.1164/rccm.201804-0646OC. [Epub ahead of print]

Parasite Immunology: Forty years on.  Riley EM1, Grencis RK2.  Parasite Immunol. 2019 Jan;41(1):e12607. doi: 10.1111/pim.12607.

Retrospective application of transposon-directed insertion-site sequencing to investigate niche-specific virulence of Salmonella Typhimurium in cattle.  Vohra P1, Chaudhuri RR2, Mayho M3, Vrettou C4, Chintoan-Uta C4, Thomson NR3, Hope JC4, Hopkins J4, Stevens MP4.  BMC Genomics. 2019 Jan 8;20(1):20. doi: 10.1186/s12864-018-5319-0.

An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade.  Vuong L1, Kouverianou E2, Rooney CM3, McHugh BJ2, Howie SE2, Gregory CD2, Forbes SJ4, Henderson NC2, Zetterberg FR5, Nilsson UJ6, et al.  Cancer Res. 2019 Jan 23. pii: canres.2244.2018. doi: 10.1158/0008-5472.CAN-18-2244. [Epub ahead of print]

Expanding the miRNA Repertoire in Atlantic Salmon; Discovery of IsomiRs and miRNAs Highly Expressed in Different Tissues and Developmental Stages.  Woldemariam NT1, Agafonov O2, Høyheim B3, Houston RD4, Taggart JB5, Andreassen R6.  Cells. 2019 Jan 11;8(1). pii: E42. doi: 10.3390/cells8010042.

Phosphatase PP2A is essential for TH17 differentiation.  Xu Q1,2, Jin X1,2,3, Zheng M1,2, Rohila D1,2, Fu G1,2, Wen Z1,2, Lou J1,2, Wu S4, Sloan R3,5, Wang L1, Hu H6, Gao X7, Lu L8,2,3,9,10.  Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):982-987. doi: 10.1073/pnas.1807484116. Epub 2018 Dec 28.

Revisiting avian 'missing' genes from de novo assembled transcripts.  Yin ZT1, Zhu F1, Lin FB1, Jia T2, Wang Z1, Sun DT2, Li GS1, Zhang CL2, Smith J3, Yang N1, Hou ZC4.  BMC Genomics. 2019 Jan 5;20(1):4. doi: 10.1186/s12864-018-5407-1.

December 2018

Dose-dependent differential resistance of inbred chicken lines to avian pathogenic Escherichia coli challenge.  Alber A1, Costa T1, Chintoan-Uta C1, Bryson KJ1, Kaiser P1, Stevens MP1, Vervelde L1.  Avian Pathol. 2018 Dec 20:1-33. doi: 10.1080/03079457.2018.1562154. [Epub ahead of print]

Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei.  Alfituri OA1, Ajibola O2,3, Brewer JM2, Garside P2, Benson RA2, Peel T4, Morrison LJ1, Mabbott NA1.  Parasite Immunol. 2018 Dec 7:e12609. doi: 10.1111/pim.12609. [Epub ahead of print]

Colonization of a commercial broiler line by Campylobacter is under limited genetic control and does not significantly impair performance or intestinal health.  Bailey RA1, Kranis A1, Psifidi A2,3, Watson KA1,2, Rothwell L2, Hocking PM2, Kaiser P2, Stevens MP2, Avendano S1.  Poult Sci. 2018 Dec 1;97(12):4167-4176. doi: 10.3382/ps/pey295.

Mobile technology and cancer screening: Lessons from rural India.  Bhatt S1, Isaac R2, Finkel M3, Evans J1, Grant L4, Paul B1,2,3,4, Weller D4.  J Glob Health. 2018 Dec;8(2):020421. doi: 10.7189/jogh.08.020421.

Comprehensive Transcriptional Profiling of the Gastrointestinal Tract of Ruminants from Birth to Adulthood Reveals Strong Developmental Stage Specific Gene Expression.  Bush SJ1, McCulloch MEB1, Muriuki C1, Salavati M1, Davis GM1, Farquhar IL1, Lisowski ZM1, Archibald AL1, Hume DA1, Clark EL2.  G3 (Bethesda). 2018 Dec 10. pii: g3.200810.2018. doi: 10.1534/g3.118.200810. [Epub ahead of print]

Streptococcus agalactiae is not always an obligate intramammary pathogen: Molecular epidemiology of GBS from milk, feces and environment in Colombian dairy herds.  Cobo-Ángel C1, Jaramillo-Jaramillo AS1, Lasso-Rojas LM1, Aguilar-Marin SB1, Sanchez J2, Rodriguez-Lecompte JC2, Ceballos-Márquez A1, Zadoks RN3,4.  PLoS One. 2018 Dec 10;13(12):e0208990. doi: 10.1371/journal.pone.0208990. eCollection 2018.

General contextual effects on neglected tropical disease risk in rural Kenya.  de Glanville WA1,2, Thomas LF1,2, Cook EAJ1,2, Bronsvoort BMC3, Wardrop N4, Wamae CN5, Kariuki S6, Fèvre EM2,7.  PLoS Negl Trop Dis. 2018 Dec 21;12(12):e0007016. doi: 10.1371/journal.pntd.0007016. [Epub ahead of print]

Effect of the duration of antimicrobial exposure on the development of antimicrobial resistance (AMR) for macrolide antibiotics: protocol for a systematic review with a network meta-analysis.  Divala TH1,2, Corbett EL3,4,5, Stagg HR6, Nliwasa M3,4, Sloan DJ7, French N8, Fielding KL3.  Syst Rev. 2018 Dec 23;7(1):246. doi: 10.1186/s13643-018-0917-0.

Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance.  Geretti AM1, White E2, Orkin C3, Tostevin A4, Tilston P5, Chadwick D6, Leen C7, Sabin C4, Dunn DT4; UK HIV Drug Resistance Database and UK CHIC Study.  J Antimicrob Chemother. 2018 Dec 13. doi: 10.1093/jac/dky468. [Epub ahead of print]

Tracking virus outbreaks in the twenty-first century.  Grubaugh ND1,2, Ladner JT3, Lemey P4, Pybus OG5, Rambaut A6,7, Holmes EC8, Andersen KG1,9.  Nat Microbiol. 2019 Jan;4(1):10-19. doi: 10.1038/s41564-018-0296-2. Epub 2018 Dec 13.

A chicken bioreactor for efficient production of functional cytokines.  Herron LR1,2, Pridans C3,4, Turnbull ML3,5, Smith N3, Lillico S3, Sherman A3, Gilhooley HJ3, Wear M6, Kurian D3, Papadakos G7, Digard P3, Hume DA3,4,8, Gill AC3,9, Sang HM10.  BMC Biotechnol. 2018 Dec 29;18(1):82. doi: 10.1186/s12896-018-0495-1.

Updated BTS Adult Bronchiectasis Guideline 2018: a multidisciplinary approach to comprehensive care.  Hill AT1, Welham SA2, Sullivan AL3, Loebinger MR4.  Thorax. 2019 Jan;74(1):1-3. doi: 10.1136/thoraxjnl-2018-212468.

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease.  Hooper KM1, Barlow PG1, Henderson P2,3, Stevens C1.  Inflamm Bowel Dis. 2018 Dec 24. doi: 10.1093/ibd/izy380. [Epub ahead of print]

Surface Charge-Dependent Cellular Uptake of Polystyrene Nanoparticles.  Jeon S1, Clavadetscher J2, Lee DK3, Chankeshwara SV4,5, Bradley M6, Cho WS7.  Nanomaterials (Basel). 2018 Dec 10;8(12). pii: E1028. doi: 10.3390/nano8121028.

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells.  Karrich JJ1, Romera-Hernández M1, Papazian N1, Veenbergen S2, Cornelissen F1, Aparicio-Domingo P1, Stenhouse FH3 et al.  Eur J Immunol. 2018 Dec 7. doi: 10.1002/eji.201847671. [Epub ahead of print]

Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes.  Melzi E1, Rocchi MS2, Entrican G2, Caporale M3, Palmarini M1.  Front Immunol. 2018 Dec 11;9:2892. doi: 10.3389/fimmu.2018.02892. eCollection 2018.

Malaria, anemia, and invasive bacterial disease: A neutrophil problem?  Mooney JP1, Galloway LJ1, Riley EM1.  J Leukoc Biol. 2018 Dec 20. doi: 10.1002/JLB.3RI1018-400R. [Epub ahead of print]

An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017).  O'Halloran C1, Hope JC1, Dobromylskyj M2, Burr P3, McDonald K3, Rhodes S4, Roberts T4, Dampney R4, De la Rua-Domenech R4, Robinson N4, Gunn-Moore DA1.  Transbound Emerg Dis. 2018 Dec;65(6):1872-1884. doi: 10.1111/tbed.12969. Epub 2018 Jul 30.

Quality control for multiple breath washout tests in multicentre bronchiectasis studies: Experiences from the BRONCH-UK clinimetrics study.  O'Neill K1, Lakshmipathy GR2, Ferguson K3, Cosgrove D3, Hill AT4, Loebinger MR5, Carroll M6 et al.  Respir Med. 2018 Dec;145:206-211. doi: 10.1016/j.rmed.2018.10.030. Epub 2018 Nov 1.

Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential.  Potey PMD1, Rossi AG1, Lucas CD1, Dorward DA1.  J Pathol. 2018 Dec 20. doi: 10.1002/path.5221. [Epub ahead of print]

Setting research priorities for global respiratory medicine within the National Institute for Health Research (NIHR) Global Health Research Unit in Respiratory Health (RESPIRE).  Rudan I1, Agrawal D2, Hussein N3, Cheong AT4, Cunningham S5, Dockerell D6, Ghazali SS4, Ghorpade D7, Habib M8, Hazir T9,10, Juvekar S2, Kawade A2, Lee PY4 et al.  J Glob Health. 2018 Dec;8(2):0201314. doi: 10.7189/jogh.08.020314.

Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in COPD: More than a Common Cold.  Sabroe I1, Ho A2, Dockrell DH3.  Am J Respir Crit Care Med. 2018 Dec 20. doi: 10.1164/rccm.201812-2283ED. [Epub ahead of print]

The Search for Efficacious New Therapies in Sepsis Needs to Embrace Heterogeneity.  Scicluna BP1, Baillie JK2,3.  Am J Respir Crit Care Med. 2018 Dec 12. doi: 10.1164/rccm.201811-2148ED. [Epub ahead of print]

Selective sweep and phylogenetic models for the emergence and spread of pyrimethamine resistance mutations in Plasmodium vivax.  Shaukat A1, Ali Q2, Connelley T3, Khan MAU1, Saleem MA1, Evans M3, Rashid I2, Sargison ND3, Chaudhry U4.  Infect Genet Evol. 2018 Dec 27;68:221-230. doi: 10.1016/j.meegid.2018.12.032. [Epub ahead of print]

RESPIRE: The National Institute for Health Research's (NIHR) Global Respiratory Health Unit.  Sheikh A1, Campbell H1, Balharry D1, Baqui AH2, Bogaert D3, Cresswell K1, Cunningham S4, Dockerell D3, El Arifeen S5, Fletcher M1, Grant L1,6 et al.  J Glob Health. 2018 Dec;8(2):020101. doi: 10.7189/jogh.08.020101.

Navigating infection risk during oviposition and cannibalistic foraging in a holometabolous insect.  Siva-Jothy JA1, Monteith KM1, Vale PF1,2.  Behav Ecol. 2018 Nov-Dec;29(6):1426-1435. doi: 10.1093/beheco/ary106. Epub 2018 Aug 9.

Can We Breed Cattle for Lower Bovine TB Infectivity?  Tsairidou S1, Allen A2, Banos G1,3, Coffey M3, Anacleto O1,4, Byrne AW2, Skuce RA2, Glass EJ1, Woolliams JA1, Doeschl-Wilson AB1.  Front Vet Sci. 2018 Dec 7;5:310. doi: 10.3389/fvets.2018.00310. eCollection 2018.

Gene-environment interactions and colorectal cancer risk: an umbrella review of systematic reviews and meta-analyses of observational studies.  Yang T1, Li X1, Montazeri Z2, Little J2, Farrington SM3,4, Ioannidis JP5,6, Dunlop MG3,4, Campbell H1, Timofeeva M3,4, Theodoratou E1,4.  Int J Cancer. 2018 Dec 11. doi: 10.1002/ijc.32057. [Epub ahead of print]

November 2018

Exploring the effect of human and animal population growth on vector-borne disease transmission with an agent-based model of Rhodesian human African trypanosomiasis in eastern province, Zambia.  Alderton S1,2,3, Macleod ET4, Anderson NE5, Machila N4,6, Simuunza M6, Welburn SC4, Atkinson PM1,2,3,7,8.  PLoS Negl Trop Dis. 2018 Nov 8;12(11):e0006905. doi: 10.1371/journal.pntd.0006905. eCollection 2018 Nov.

Unravelling the glial response in the pathogenesis of Alzheimer's disease.  Alibhai JD1,2, Diack AB3, Manson JC4.  FASEB J. 2018 Nov;32(11):5766-5777. doi: 10.1096/fj.201801360R.

Predicting reservoir hosts and arthropod vectors from evolutionary signatures in RNA virus genomes.  Babayan SA1,2, Orton RJ3, Streicker DG4,3.  Science. 2018 Nov 2;362(6414):577-580. doi: 10.1126/science.aap9072.

Allelic nomenclature for the duplicated MHC class II DQ genes in sheep.  Ballingall KT1, Dicks K2, Kyriazopoulou P3,2, Herrmann-Hoesing L4. Immunogenetics. 2018 Nov 10. doi: 10.1007/s00251-018-1096-9. [Epub ahead of print]

An official nomenclature for the Major Histocompatibility Complex allele sequences from the domestic goat (Capra hircus). Ballingall KT1, Todd H1.  HLA. 2018 Nov 22. doi: 10.1111/tan.13425. [Epub ahead of print]

Dissecting the Genomic Architecture of Resistance to Eimeria maxima Parasitism in the Chicken.  Boulton K1, Nolan MJ2, Wu Z1, Riggio V1, Matika O1, Harman K2, Hocking PM1, Bumstead N3 et al.  Front Genet. 2018 Nov 26;9:528. doi: 10.3389/fgene.2018.00528. eCollection 2018. 

The impact of anthelmintic drugs on weight gain of smallholder goats in subtropical regions.  Bessell PR1, Sargison ND2, Mirende K3, Dash R4, Prasad S5, Al-Riyami L6, Gammon N6, Stuke K7, Woolley R6, Barbaruah M5, Wambura P3. Prev Vet Med. 2018 Nov 1;159:72-81. doi: 10.1016/j.prevetmed.2018.08.014. Epub 2018 Sep 1.

Phenotypic and genetic variation in the response of chickens to Eimeria tenella induced coccidiosis.  Boulton K1, Nolan MJ2, Wu Z3, Psifidi A3,4, Riggio V3, Harman K2, Bishop SC3, Kaiser P3, Abrahamsen MS5, Hawken R5, Watson KA3, Tomley FM2, Blake DP2, Hume DA6,7.  Genet Sel Evol. 2018 Nov 21;50(1):63. doi: 10.1186/s12711-018-0433-7.

Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2.  Bray C1, Wright D1, Haupt S1, Thomas S2, Stauss H2, Zamoyska R1.  Front Immunol. 2018 Nov 12;9:2595. doi: 10.3389/fimmu.2018.02595. eCollection 2018.

Draft Genome Assembly of the Poultry Red Mite, Dermanyssus gallinae.  Burgess STG1, Bartley K1, Nunn F1, Wright HW1, Hughes M2, Gemmell M2, Haldenby S2, Paterson S2 et al.  Microbiol Resour Announc. 2018 Nov 8;7(18). pii: e01221-18. doi: 10.1128/MRA.01221-18. eCollection 2018 Nov.

The impact of meridian balance method electro-acupuncture treatment on chronic pelvic pain in women: a three-armed randomised controlled feasibility study using a mixed-methods approach.  Chong OT1, Critchley HO1, Williams LJ2, Haraldsdottir E3, Horne AW1, Fallon M4.  Br J Pain. 2018 Nov;12(4):238-249. doi: 10.1177/2049463718776044. Epub 2018 May 14.

The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.  Fernandes PM1, Kinkead JR1, McNae IW2, Michels PA2, Walkinshaw MD3.  Biochem J. 2018 Nov 7. pii: BCJ20180635. doi: 10.1042/BCJ20180635. [Epub ahead of print]

Population level changes in schistosome specific antibody levels following chemotherapy.  Fukushige M1, Mutapi F2, Woolhouse MEJ3.  Parasite Immunol. 2018 Nov 22:e12604. doi: 10.1111/pim.12604. [Epub ahead of print]

Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity.  Furniss JJ1, Grey H1, Wang Z1, Nomoto M2, Jackson L1, Tada Y2, Spoel SH1.  PLoS Pathog. 2018 Nov 20;14(11):e1007447. doi: 10.1371/journal.ppat.1007447. [Epub ahead of print]

Assembly of a Parts List of the Human Mitotic Cell Cycle Machinery.  Giotti B1,2, Chen SH1, Barnett MW1, Regan T1, Ly T3, Wiemann S4, Hume DA1,5, Freeman TC1.  J Mol Cell Biol. 2018 Nov 17. doi: 10.1093/jmcb/mjy063. [Epub ahead of print]

Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line.  Haga IR1,2, Simpson JL2, Hawes PC2, Beard PM3,4.  Sci Rep. 2018 Nov 16;8(1):16956. doi: 10.1038/s41598-018-34732-w. 

Comparative genomics of the major parasitic worms.  International Helminth Genomes Consortium.  Nat Genet. 2018 Nov 5. doi: 10.1038/s41588-018-0262-1. [Epub ahead of print]

Dynamics of Colon Monocyte and Macrophage Activation During Colitis.  Jones GR1,2, Bain CC3, Fenton TM1, Kelly A1,4, Brown SL1, Ivens AC2, Travis MA1,4, Cook PC1, MacDonald AS1.  Front Immunol. 2018 Nov 27;9:2764. doi: 10.3389/fimmu.2018.02764. eCollection 2018.

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.  Ligthart S1, Vaez A2, Võsa U3, Stathopoulou MG4, de Vries PS5, Prins BP6, Van der Most PJ7, Tanaka T8, Naderi E9, Rose LM10, Wu Y11 et al.  Am J Hum Genet. 2018 Nov 1;103(5):691-706. doi: 10.1016/j.ajhg.2018.09.009.

The Influence of Parasite Infections on Host Immunity to Co-infection With Other Pathogens.  Mabbott NA1.  Front Immunol. 2018 Nov 8;9:2579. doi: 10.3389/fimmu.2018.02579. eCollection 2018.

PD-1 expression is upregulated on adapted T cells in experimental autoimmune encephalomyelitis but is not required to maintain a hyporesponsive state.  Mair I1, Besusso D1, Saul L1, Patel SD1, Ravindran R1, McPherson RC1, Leech MD1, O'Connor RA1, Anderton SM1, Mellanby RJ1,2.  Eur J Immunol. 2018 Nov 28. doi: 10.1002/eji.201847868. [Epub ahead of print]

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules.  Maizels RM1, Smits HH2, McSorley HJ3.  Immunity. 2018 Nov 20;49(5):801-818. doi: 10.1016/j.immuni.2018.10.016.

Gene silencing by RNA interference in the ectoparasitic mite, Psoroptes ovis.  Marr EJ1,2, Wright HW1, Sargison ND3, Nisbet AJ1, Burgess STG4.  Vet Res. 2018 Nov 1;49(1):112. doi: 10.1186/s13567-018-0608-9.

100 Questions in Livestock Helminthology Research.  Morgan ER1, Aziz NA2, Blanchard A3, Charlier J4, Charvet C5, Claerebout E6, Geldhof P6, Greer AW7, Hertzberg H8, Hodgkinson J9 et al.  Trends Parasitol. 2018 Nov 23. pii: S1471-4922(18)30237-X. doi: 10.1016/j.pt.2018.10.006. [Epub ahead of print]

Integrated management of non-communicable diseases in low-income settings: palliative care, primary care and community health synergies.  Munday D1, Kanth V2, Khristi S2, Grant L3.  BMJ Support Palliat Care. 2018 Nov 1. pii: bmjspcare-2018-001579. doi: 10.1136/bmjspcare-2018-001579. [Epub ahead of print]

2018 International Consensus Statement on Golf and Health to guide action by people, policymakers and the golf industry.  Murray AD1,2, Archibald D3,4, Murray IR5, Hawkes RA6,7, Foster C8,9, Barker K10, Kelly P1, Grant L11, Mutrie N1.  Br J Sports Med. 2018 Nov;52(22):1426-14361. doi: 10.1136/bjsports-2018-099509. Epub 2018 Sep 23.

Cytokine and Chemokine Concentrations as Biomarkers of Feline Mycobacteriosis.  O'Halloran C1, McCulloch L2, Rentoul L3, Alexander J4, Hope JC5, Gunn-Moore DA5.  Sci Rep. 2018 Nov 23;8(1):17314. doi: 10.1038/s41598-018-35571-5.

Induction and suppression of NF-κB signalling by a DNA virus of Drosophila.  Palmer WH1,2, Joosten J3, Overheul GJ3, Jansen PW4, Vermeulen M4, Obbard DJ5,2, Van Rij RP6.  J Virol. 2018 Nov 7. pii: JVI.01443-18. doi: 10.1128/JVI.01443-18. [Epub ahead of print]

Plasmodium-specific atypical memory B cells are short-lived activated B cells.  Pérez-Mazliah D1, Gardner PJ2, Schweighoffer E1, McLaughlin S1, Hosking C1, Tumwine I1, Davis RS3,4,5, Potocnik AJ6, Tybulewicz VL1, Langhorne J1.  Elife. 2018 Nov 2;7. pii: e39800. doi: 10.7554/eLife.39800.

Whole Genome Sequencing for Determining the Source of Mycobacterium bovis Infections in Livestock Herds and Wildlife in New Zealand.  Price-Carter M1, Brauning R2, de Lisle GW1, Livingstone P3, Neill M4, Sinclair J5, Paterson B6 et al.  Front Vet Sci. 2018 Oct 30;5:272. doi: 10.3389/fvets.2018.00272. eCollection 2018.

The Genomic Architecture of Fowl Typhoid Resistance in Commercial Layers.  Psifidi A1,2, Russell KM1, Matika O1, Sánchez-Molano E1, Wigley P3, Fulton JE4, Stevens MP1, Fife MS5.  Front Genet. 2018 Nov 19;9:519. doi: 10.3389/fgene.2018.00519. eCollection 2018.

Characterisation of the British honey bee metagenome.  Regan T1, Barnett MW2, Laetsch DR3, Bush SJ2, Wragg D2, Budge GE4,5, Highet F6, Dainat B7, de Miranda JR8, Watson M2, Blaxter M9, Freeman TC10.  Nat Commun. 2018 Nov 26;9(1):4995. doi: 10.1038/s41467-018-07426-0.

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing.  Rojas F1, Silvester E1, Young J1, Milne R1, Tettey M1, Houston DR2, Walkinshaw MD2 et al.  Cell. 2018 Nov 27. pii: S0092-8674(18)31397-7. doi: 10.1016/j.cell.2018.10.041. [Epub ahead of print]

Structure and function of Per-ARNT-Sim domains and their possible role in the life-cycle biology of Trypanosoma cruzi.  Rojas-Pirela M1, Rigden DJ2, Michels PA3, Cáceres AJ1, Concepción JL1, Quiñones W4.  Mol Biochem Parasitol. 2018 Jan;219:52-66. doi: 10.1016/j.molbiopara.2017.11.002. Epub 2017 Nov 11.

Adaptive plasticity in the gametocyte conversion rate of malaria parasites.  Schneider P1, Greischar MA2, Birget PLG1, Repton C1, Mideo N2, Reece SE1.  PLoS Pathog. 2018 Nov 14;14(11):e1007371. doi: 10.1371/journal.ppat.1007371. [Epub ahead of print]

Development of superficial lung lesions monitored on farm by serial ultrasonographic examination in sheep with lesions confirmed as ovine pulmonary adenocarcinoma at necropsy.  Scott PR1, Dagleish MP2, Cousens C2.  Ir Vet J. 2018 Nov 5;71:23. doi: 10.1186/s13620-018-0134-0. eCollection 2018.

Natural Selection on Antihelminth Antibodies in a Wild Mammal Population.  Sparks AM, Watt K, Sinclair R, Pilkington JG, Pemberton JM, Johnston SE, McNeilly TN, Nussey DH.  Am Nat. 2018 Dec;192(6):745-760. doi: 10.1086/700115. Epub 2018 Oct 10.

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.  Tait-Burkard C1, Doeschl-Wilson A1, McGrew MJ1, Archibald AL1, Sang HM1, Houston RD1, Whitelaw CB1, Watson M2.  Genome Biol. 2018 Nov 26;19(1):204. doi: 10.1186/s13059-018-1583-1.

Generation of Markerless Deletions in the Nosocomial Pathogen Clostridium difficile by induction of DNA Double-strand Breaks.  Theophilou ES1,2, Vohra P2,3, Gallagher MP1, Poxton IR2, Blakely GW4.  Appl Environ Microbiol. 2018 Nov 26. pii: AEM.02055-18. doi: 10.1128/AEM.02055-18. [Epub ahead of print]

Characterising the respiratory microbiome.  Watson RL1, de Koff EM2,3, Bogaert D1,2.  Eur Respir J. 2018 Nov 28. pii: 1801711. doi: 10.1183/13993003.01711-2018. [Epub ahead of print]

Inflammation and Hypoxia: HIF and PHD Isoform Selectivity.  Watts ER1, Walmsley SR2.  Trends Mol Med. 2018 Nov 12. pii: S1471-4914(18)30202-8. doi: 10.1016/j.molmed.2018.10.006. [Epub ahead of print]

Why "Culture" matters for planetary health.  Wilson M1, Gathorne-Hardy A2, Alexander P2, Boden L2.  Lancet Planet Health. 2018 Nov;2(11):e467-e468. doi: 10.1016/S2542-5196(18)30205-5.

October 2018

In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A.  Akram AR1,2, Chankeshwara SV3,4, Scholefield E3, Aslam T4, McDonald N2, Megia-Fernandez A3,4, Marshall A3,2, Mills B3 et al, Sci Transl Med. 2018 Oct 24;10(464). pii: eaal0033. doi: 10.1126/scitranslmed.aal0033.

Microbial population dynamics and evolution: a statistical physicist's guide.  Allen RJ1, Waclaw B1.  Rep Prog Phys. 2018 Oct 1. doi: 10.1088/1361-6633/aae546. [Epub ahead of print]

Development of an in-house ELISA to detect anti-HPV16-L1 antibodies in serum and dried blood spots.  Bhatia R1, Stewart J2, Moncur S2, Cubie H3, Kim K4, Pollock KG5, Busby-Earle C6, Williams AR7, Howie S2, Cuschieri K8.  J Virol Methods. 2018 Oct 20. pii: S0166-0934(18)30306-9. doi: 10.1016/j.jviromet.2018.10.007. [Epub ahead of print]

Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models.  Boyle AK1, Rinaldi SF1, Rossi AG2, Saunders PTK2, Norman JE1.  FASEB J. 2018 Oct 12:fj201801104R. doi: 10.1096/fj.201801104R. [Epub ahead of print]

Network analysis of the social and demographic influences on name choice within the UK (1838-2016).  Bush SJ1, Powell-Smith A2, Freeman TC1.  PLoS One. 2018 Oct 31;13(10):e0205759. doi: 10.1371/journal.pone.0205759. eCollection 2018.

Validation of the incremental shuttle walk test as a clinical endpoint in bronchiectasis.  Cartlidge MK1, Smith MP2, Bedi P3, Donaldson S3, Clarke A4, Mantoani LC5, Rabinovich RA6, Rossi AG3, Hill AT7.  Chest. 2018 Oct 6. pii: S0012-3692(18)32558-3. doi: 10.1016/j.chest.2018.09.019. [Epub ahead of print]

Basal Instinct: Persistence of Barrier Dysfunction.  Chauché C1, McSorley HJ2.  Immunity. 2018 Oct 16;49(4):590-592. doi: 10.1016/j.immuni.2018.09.022.

Genome hypermobility by lateral transduction.  Chen J#1, Quiles-Puchalt N#2, Chiang YN#3, Bacigalupe R4, Fillol-Salom A2, Chee MSJ3, Fitzgerald JR4, Penadés JR5,6,7.  Science. 2018 Oct 12;362(6411):207-212. doi: 10.1126/science.aat5867.

S-nitrosylation of the zinc finger protein SRG1 regulates plant immunity.  Cui B1,2,3, Pan Q1,2,3, Clarke D4, Villarreal MO3, Umbreen S3, Yuan B1,2, Shan W5, Jiang J1,2, Loake GJ6,7.  Nat Commun. 2018 Oct 12;9(1):4226. doi: 10.1038/s41467-018-06578-3.

A growing bacterial colony in two dimensions as an active nematic.  Dell'Arciprete D1,2, Blow ML1, Brown AT1, Farrell FDC1,3, Lintuvuori JS4, McVey AF1, Marenduzzo D5, Poon WCK1.  Nat Commun. 2018 Oct 10;9(1):4190. doi: 10.1038/s41467-018-06370-3.

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells.  Driedonks TAP1, van der Grein SG1, Ariyurek Y2,3, Buermans HPJ2,3, Jekel H1, Chow FWN4, Wauben MHM1, Buck AH4, 't Hoen PAC2,5, Nolte-'t Hoen ENM6.  Cell Mol Life Sci. 2018 Oct;75(20):3857-3875. doi: 10.1007/s00018-018-2842-8. Epub 2018 May 28.

Non-invasive 19F NMR analysis of a protein-templated N-acylhydrazone dynamic combinatorial library.  Ekström AG1, Wang JT1, Bella J1, Campopiano DJ1.  Org Biomol Chem. 2018 Oct 18. doi: 10.1039/c8ob01918e. [Epub ahead of print]

Antiviral activity of the mineralocorticoid receptor NR3C2 against Herpes simplex virus Type 1 (HSV-1) infection.  Haas JG1, Weber J1, Gonzalez O2, Zimmer R2, Griffiths SJ3.  Sci Rep. 2018 Oct 26;8(1):15876. doi: 10.1038/s41598-018-34241-w.

Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials.  He Y1, Li X2, Gasevic D3, Brunt E4, McLachlan F4, Millenson M5, Timofeeva M2, Ioannidis JPA6, Campbell H2, Theodoratou E2.  Ann Intern Med. 2018 Oct 16;169(8):543-553. doi: 10.7326/M18-0808. Epub 2018 Oct 9.

Adult Outpatients with Acute Cough due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report.  Hill AT1, Gold PM2, El Solh A3, Metlay JP4, Ireland B5, Irwin RS6; CHEST Expert Cough Panel.  Chest. 2018 Oct 5. pii: S0012-3692(18)32499-1. doi: 10.1016/j.chest.2018.09.016. [Epub ahead of print]

Giardia duodenalis in the UK: current knowledge of risk factors and public health implications.  Horton B1, Bridle H2, Alexander CL3, Katzer F1.  Parasitology. 2018 Oct 15:1-12. doi: 10.1017/S0031182018001683. [Epub ahead of print]

Mutation of influenza A virus PA-X decreases pathogenicity in chicken embryos and can increase the yield of reassortant candidate vaccine viruses.  Hussain S1, Turnbull ML1, Wise HM1, Jagger BW2,3, Beard PM1,4, Kovacikova K1, Taubenberger JK3, Vervelde L1, Engelhardt OG5, Digard P6.  J Virol. 2018 Oct 31. pii: JVI.01551-18. doi: 10.1128/JVI.01551-18. [Epub ahead of print]

Bronchiolitis needs a revisit: distinguishing between virus entities and their treatments.  Jartti T1, Smits HH2, Bonnelykke K3, Cavkaytar O4, Elenius V1, Konradsen JR5,6,7, Maggina P8, Makrinioti H9, Stokholm J3, Hedlin G5,6 et al.  Allergy. 2018 Oct 1. doi: 10.1111/all.13624. [Epub ahead of print]

Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis.  Krishnan S1,2, Prise IE1,2, Wemyss K1,2, Schenck LP3, Bridgeman HM1,2, McClure FA1,2, Zangerle-Murray T1 et al.  Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10738-10743. doi: 10.1073/pnas.1802320115. Epub 2018 Oct 2.

Detection and differentiation of five diarrhea related pig viruses utilizing a multiplex PCR assay.  Liu G1, Jiang Y2, Opriessnig T3, Gu K1, Zhang H4, Yang Z1.  J Virol Methods. 2018 Oct 15. pii: S0166-0934(18)30363-X. doi: 10.1016/j.jviromet.2018.10.009. [Epub ahead of print]

Respiratory Microbiota Predicts Clinical Disease Course of Acute Otorrhea in Children With Tympanostomy Tubes.  Man WH1,2, van Dongen TMA3, Venekamp RP3, Pluimakers VG1, Chu MLJN1,4, van Houten MA2, Sanders EAM1, Schilder AGM5, Bogaert D1,6.  Pediatr Infect Dis J. 2018 Oct 5. doi: 10.1097/INF.0000000000002215. [Epub ahead of print]

Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.  Mao SPH1, Park M1, Cabrera RM1, Christin JR2, Karagiannis GS1,3,4, Oktay MH1,3,4, Zaiss DMW5, Abrams SI6, Guo W2, Condeelis JS1,3,4, Kenny PA7, Segall JE8,9.  Breast Cancer Res. 2018 Oct 26;20(1):131. doi: 10.1186/s13058-018-1057-0.

Antigenic and sequence variability of the human respiratory syncytial virus F glycoprotein compared to related viruses in a comprehensive dataset.  Mas V1, Nair H2, Campbell H2, Melero JA1, Williams TC3.  Vaccine. 2018 Oct 29;36(45):6660-6673. doi: 10.1016/j.vaccine.2018.09.056. Epub 2018 Oct 3.

A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast.  Mendoza-Ochoa GI1,2, Barrass JD1, Terlouw BR1, Maudlin IE1, de Lucas S1, Sani E1, Aslanzadeh V1,3, Reid JAE1,4, Beggs JD1.  Yeast. 2018 Oct 29. doi: 10.1002/yea.3362. [Epub ahead of print]

SNP markers for the genetic characterization of Mexican shrimp broodstocks.  Perez-Enriquez R1, Robledo D2, Houston RD2, Llera-Herrera R3.  Genomics. 2018 Oct 9. pii: S0888-7543(18)30376-8. doi: 10.1016/j.ygeno.2018.10.001. [Epub ahead of print]

Impact of Genetic Selection for Increased Cattle Resistance to Bovine Tuberculosis on Disease Transmission Dynamics.  Raphaka K1,2, Sánchez-Molano E1, Tsairidou S1, Anacleto O1,3, Glass EJ1, Woolliams JA1, Doeschl-Wilson A1, Banos G1,4.  Front Vet Sci. 2018 Oct 1;5:237. doi: 10.3389/fvets.2018.00237. eCollection 2018.

Is palliative care cost-effective in low-income and middle-income countries? A mixed-methods systematic review.  Reid EA1, Kovalerchik O2, Jubanyik K2, Brown S3, Hersey D4, Grant L5.  BMJ Support Palliat Care. 2018 Oct 1. pii: bmjspcare-2018-001499. doi: 10.1136/bmjspcare-2018-001499. [Epub ahead of print]

Adaptive periodicity in the infectivity of malaria gametocytes to mosquitoes.  Schneider P1, Rund SSC2,3, Smith NL2, Prior KF2, O'Donnell AJ2, Reece SE2.  Proc Biol Sci. 2018 Oct 3;285(1888). pii: 20181876. doi: 10.1098/rspb.2018.1876.

Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study.  Shankar-Hari M1,2, Datta D3, Wilson J4,5, Assi V6,7, Stephen J7, Weir CJ6,7, Rennie J3, Antonelli J6 et al.  Intensive Care Med. 2018 Oct 5. doi: 10.1007/s00134-018-5389-0. [Epub ahead of print]

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development.  Silvester E1, Ivens A1, Matthews KR1.  PLoS Negl Trop Dis. 2018 Oct 11;12(10):e0006863. doi: 10.1371/journal.pntd.0006863. eCollection 2018 Oct.

Visualisation and characterisation of mononuclear phagocytes in the chicken respiratory tract using CSF1R-transgenic chickens.  Sutton K1, Costa T2, Alber A2, Bryson K2, Borowska D2, Balic A2, Kaiser P2, Stevens M2, Vervelde L2.  Vet Res. 2018 Oct 10;49(1):104. doi: 10.1186/s13567-018-0598-7.

Developmental roadmap for antimicrobial susceptibility testing systems.  van Belkum A1, Bachmann TT2, Lüdke G3, Lisby JG4, Kahlmeter G5, Mohess A6, Becker K7, Hays JP8, Woodford N9, Mitsakakis K10 et al.  Nat Rev Microbiol. 2018 Oct 17. doi: 10.1038/s41579-018-0098-9. [Epub ahead of print]

ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages.  Waddell LA1, Lefevre L1, Bush SJ2, Raper A1, Young R1, Lisowski ZM1,3, McCulloch MEB1, Muriuki C1, Sauter KA1, Clark EL1, Irvine KM4, Pridans C5, Hope JC1, Hume DA4,5.  Front Immunol. 2018 Oct 1;9:2246. doi: 10.3389/fimmu.2018.02246. eCollection 2018.

High genetic diversity in the Dirofilaria repens species complex revealed by mitochondrial genomes of feline microfilaria samples from Narathiwat, Thailand.  Yilmaz E1, Wongkamchai S2, Ramünke S1, Koutsovoulos GD3, Blaxter ML3,4, Poppert S5,6, Schaper R7, von Samson-Himmelstjerna G1, Krücken J1.  Transbound Emerg Dis. 2018 Oct 3. doi: 10.1111/tbed.13033. [Epub ahead of print]

Evidence for an Unknown Agent Antigenically Related to the Hepatitis E Virus in Dairy Cows in the United States.  Yugo DM1, Cossaboom CM1, Heffron CL1, Huang YW1, Kenney SP1, Woolums AR2, Hurley DJ3, Opriessnig T4, Li L5, Delwart E5, Kanevsky I6, Meng XJ1.  J Med Virol. 2018 Oct 14. doi: 10.1002/jmv.25339. [Epub ahead of print]

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.  Jochems SP1, Marcon F2, Carniel BF3, Holloway M3, Mitsi E3, Smith E3, Gritzfeld JF3, Solórzano C3, Reiné J3, Pojar S3, Nikolaou E3, et al.  Nat Immunol. 2018 Oct 29. doi: 10.1038/s41590-018-0231-y. [Epub ahead of print]

September 2018

The Long Wait for a New Drug for Human African Trypanosomiasis.  Baker CH1, Welburn SC2.  Trends Parasitol. 2018 Sep 1. pii: S1471-4922(18)30171-5. doi: 10.1016/j.pt.2018.08.006. [Epub ahead of print].

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis.  Barth ND1, Marwick JA1, Heeb MJ2, Gale AJ2, Rossi AG1, Dransfield I3.  J Immunol. 2018 Sep 24. pii: ji1800249. doi: 10.4049/jimmunol.1800249. [Epub ahead of print].

The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium.  Bonde J1, Ejegod DM2, Cuschieri K3, Dillner J4, Heideman DAM5, Quint W6, Pavon Ribas MA7, Padalko E8, Christiansen IK9, Xu L10, Arbyn M10.  J Clin Virol. 2018 Sep 17;108:64-71. doi: 10.1016/j.jcv.2018.09.012. [Epub ahead of print].

The Aarhus statement on cancer diagnostic research: turning recommendations into new survey instruments.  Coxon D1, Campbell C1, Walter FM2, Scott SE3, Neal RD4, Vedsted P5, Emery J6, Rubin G7, Hamilton W8, Weller D9.  BMC Health Serv Res. 2018 Sep 3;18(1):677. doi: 10.1186/s12913-018-3476-0.

Super-silent FRET Sensor Enables Live Cell Imaging and Flow Cytometric Stratification of Intracellular Serine Protease Activity in Neutrophils.  Craven TH1, Avlonitis N2, McDonald N3, Walton T2, Scholefield E1, Akram AR1, Walsh TS4, Haslett C1, Bradley M2, Dhaliwal K5.  Sci Rep. 2018 Sep 10;8(1):13490. doi: 10.1038/s41598-018-31391-9.

TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei.  Faktorová D1, Bär A2, Hashimi H3, McKenney K4, Horák A3, Schnaufer A5, Rubio MAT4, Alfonzo JD6, Lukeš J3.  Mol Biochem Parasitol. 2018 Sep 21;225:84-93. doi: 10.1016/j.molbiopara.2018.09.003. [Epub ahead of print]

Survival of Mycobacterium avium subspecies paratuberculosis in retail pasteurised milk.  Gerrard ZE1, Swift BMC2, Botsaris G3, Davidson RS4, Hutchings MR4, Huxley JN5, Rees CED5.  Food Microbiol. 2018 Sep;74:57-63. doi: 10.1016/j.fm.2018.03.004. Epub 2018 Mar 9.

The cellular and pathologic prion protein.  Gill AC1, Castle AR2.  Handb Clin Neurol. 2018;153:21-44. doi: 10.1016/B978-0-444-63945-5.00002-7.

Amikacin Liposome Inhalation Suspension for Treatment-Refractory Lung Disease Caused by Mycobacterium avium Complex (CONVERT): A Prospective, Open-Label, Randomized Study.  Griffith DE1, Eagle G2, Thomson R3,4, Aksamit TR5, Hasegawa N6, Morimoto K7 et al.  Am J Respir Crit Care Med. 2018 Sep 14. doi: 10.1164/rccm.201807-1318OC. [Epub ahead of print]

Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei.  Kent RS1,2, Modrzynska KK3,4, Cameron R1, Philip N1,5, Billker O6, Waters AP7.  Nat Microbiol. 2018 Sep 3. doi: 10.1038/s41564-018-0223-6. [Epub ahead of print]

IFITM proteins inhibit HIV-1 protein synthesis.  Lee WJ1, Fu RM2, Liang C3, Sloan RD4,5,6.  Sci Rep. 2018 Sep 28;8(1):14551. doi: 10.1038/s41598-018-32785-5.

PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo.  Loynes CA1, Lee JA1, Robertson AL1,2, Steel MJ1, Ellett F1,3, Feng Y4, Levy BD5, Whyte MKB4, Renshaw SA1.  Sci Adv. 2018 Sep 5;4(9):eaar8320. doi: 10.1126/sciadv.aar8320. eCollection 2018 Sep.

The role of the immune system in prion infection.  Mabbott NA1, Alibhai JD2, Manson J3.  Handb Clin Neurol. 2018;153:85-107. doi: 10.1016/B978-0-444-63945-5.00005-2.

Oral Prion Neuroinvasion Occurs Independently of PrPC Expression in the Gut Epithelium.  Marshall A1, Bradford BM1, Clarke AR2, Manson JC3, Mabbott NA4.  J Virol. 2018 Sep 12;92(19). pii: e01010-18. doi: 10.1128/JVI.01010-18. Print 2018 Oct 1.

Body Protein Reserves Sustain Maternal Performance in Early Lactation but Dietary Protein Is Necessary to Maintain Performance and Immune Responses to Nippostrongylus brasiliensis in Lactating Rats.  Masuda A1, Houdijk JGM1, Allen JE2, Athanasiadou S1.  J Nutr. 2018 Sep 10. doi: 10.1093/jn/nxy133. [Epub ahead of print]

Rapid and robust analytical protocol for E. coli STEC bacteria subspecies differentiation using whole cell MALDI mass spectrometry.  Mclean K1, Palarea-Albaladejo J2, Currie CG3, Imrie LHJ4, Manson EDT5, Fraser-Pitt D6, Wright F7, Alexander CJ8, Pollock KGJ9, Allison L10, Hanson M11, Smith DGE12.  Talanta. 2018 May 15;182:164-170. doi: 10.1016/j.talanta.2018.01.055. Epub 2018 Feb 20.

Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer.  Megia-Fernandez A1, Mills B2, Michels C2, Chankeshwara SV1, Krstajić N3, Haslett C2, Dhaliwal K2, Bradley M1.  Org Biomol Chem. 2018 Sep 3. doi: 10.1039/c8ob01790e. [Epub ahead of print]

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation.  Mitchell AR1, Yuan M2, Morgan HP1, McNae IW2, Blackburn EA2, LeBihan T1, Homem RA1, Yu M1, Loake GJ3, Michels PA2, Wear MA2, Walkinshaw MD4.  Biochem J. 2018 Sep 25. pii: BCJ20180556. doi: 10.1042/BCJ20180556. [Epub ahead of print]

Immune cell gene signatures for profiling the microenvironment of solid tumors.  Nirmal AJ1, Regan T1, Shih BB1, Hume DA1, Sims AH2, Freeman TC3.  Cancer Immunol Res. 2018 Sep 28. pii: canimm.0342.2018. doi: 10.1158/2326-6066.CIR-18-0342. [Epub ahead of print]

Expansion of the metazoan virosphere: progress, pitfalls, and prospects.  Obbard DJ1.  Curr Opin Virol. 2018 Sep 17;31:17-23. doi: 10.1016/j.coviro.2018.08.008. [Epub ahead of print]

Molecular identification of bovine trypanosomes in relation to cattle sources in southwest Nigeria.  Odeniran PO1, Macleod ET2, Ademola IO3, Welburn SC4.  Parasitol Int. 2018 Sep 20. pii: S1383-5769(18)30310-6. doi: 10.1016/j.parint.2018.09.005. [Epub ahead of print]

Coinfections and comorbidities in African health systems: At the interface of infectious and noninfectious diseases.  Osakunor DNM1, Sengeh DM2, Mutapi F1,3.  PLoS Negl Trop Dis. 2018 Sep 20;12(9):e0006711. doi: 10.1371/journal.pntd.0006711. eCollection 2018 Sep.

Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge.  Patel NP1,2, Vukmanovic-Stejic M1, Suarez-Farinas M3, Chambers ES1, Sandhu D1,2, Fuentes-Duculan J3, Mabbott NA4,5, Rustin MHA2, Krueger J3, Akbar AN1.  J Infect Dis. 2018 Sep 22;218(suppl_2):S88-S98. doi: 10.1093/infdis/jiy420.

Effects of mutations in the effector domain of influenza A virus NS1 protein.  Pereira CF1,2, Wise HM1,3,4, Kurian D3, Pinto RM3, Amorim MJ1,5, Gill AC3,6, Digard P7,8.  BMC Res Notes. 2018 Sep 18;11(1):673. doi: 10.1186/s13104-018-3779-6.

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus.  Pridans C1,2, Raper A3, Davis GM3, Alves J3, Sauter KA3, Lefevre L3, Regan T3, Meek S3, Sutherland L3, Thomson AJ3,4, Clohisey S3 et al.  J Immunol. 2018 Sep 24. pii: ji1701783. doi: 10.4049/jimmunol.1701783. [Epub ahead of print]

Antiviral innate immune response in non-myeloid cells is augmented by chloride ions via an increase in intracellular hypochlorous acid levels.  Ramalingam S1,2, Cai B3, Wong J3, Twomey M3, Chen R3, Fu RM3, Boote T3, McCaughan H4, Griffiths SJ3, Haas JG4,3.  Sci Rep. 2018 Sep 11;8(1):13630. doi: 10.1038/s41598-018-31936-y.

Staphylococcus pseudintermedius Surface Protein L (SpsL) Is Required for Abscess Formation in a Murine Cutaneous Infection Model.  Richards AC1, O'Shea M1, Beard PM1, Goncheva MI1, Tuffs SW1, Fitzgerald JR2, Lengeling A2.  Infect Immun. 2018 Sep 4. pii: IAI.00631-18. doi: 10.1128/IAI.00631-18. [Epub ahead of print]

Public health significance of Campylobacter spp. colonisation of wild game pheasants (Phasianus colchicus) in Scotland.  Seguino A1, Chintoan-Uta C2, Smith SH2, Shaw DJ2.  Food Microbiol. 2018 Sep;74:163-170. doi: 10.1016/j.fm.2018.04.002. Epub 2018 Apr 7.

Evidence of a distinct group of Black African patients with systemic lupus erythematosus.  Sibanda EN1,2, Chase-Topping M3, Pfavayi LT1, Woolhouse MEJ2,4, Mutapi F2,5.  BMJ Glob Health. 2018 Sep 16;3(5):e000697. doi: 10.1136/bmjgh-2017-000697. eCollection 2018.

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion.  Smith KA1, Löser S2, Varyani F3, Harcus Y3, McSorley HJ3, McKenzie AN4, Maizels RM2.  Elife. 2018 Sep 21;7. pii: e38269. doi: 10.7554/eLife.38269. [Epub ahead of print]

Sex-dependent changes in neuroactive steroid concentrations in the rat brain following acute swim stress.  Sze Y1,2, Gill AC2,3, Brunton PJ1,2.  J Neuroendocrinol. 2018 Sep 8:e12644. doi: 10.1111/jne.12644. [Epub ahead of print]

Estimating selection on the act of inbreeding in a population with strong inbreeding depression.  Troianou E1, Huisman J1, Pemberton JM1, Walling CA1.  J Evol Biol. 2018 Sep 19. doi: 10.1111/jeb.13376. [Epub ahead of print]

The biofilm eradication activity of acetic acid in the management of periprosthetic joint infection.  Tsang STJ1, Gwynne PJ2, Gallagher MP2, Simpson AHRW3.  Bone Joint Res. 2018 Sep 15;7(8):517-523. doi: 10.1302/2046-3758.78.BJR-2018-0045.R1. eCollection 2018 Aug.

Validation of EUROArray HPV test using the VALGENT framework.  Viti J1, Poljak M2, Oštrbenk A2, Bhatia R1, Alcañiz Boada E1, Cornall AM3, Cuschieri K4, Garland S5, Xu L6, Arbyn M6.  J Clin Virol. 2018 Sep 10;108:38-42. doi: 10.1016/j.jcv.2018.09.005. [Epub ahead of print]

Bovine Staphylococcus aureus superantigens stimulate the entire T cell repertoire of cattle.  Wilson GJ1,2, Tuffs SW1, Wee BA1, Seo KS3, Park N3, Connelley T1, Guinane CM1, Morrison WI1, Fitzgerald JR4.  Infect Immun. 2018 Sep 10. pii: IAI.00505-18. doi: 10.1128/IAI.00505-18. [Epub ahead of print]

The prevalence of brucellosis and bovine tuberculosis in ruminants in Sidi Kacem Province, Morocco.  Yahyaoui Azami H1,2,3, Ducrotoy MJ4, Bouslikhane M1, Hattendorf J2,3, Thrusfield M5 et al.  PLoS One. 2018 Sep 18;13(9):e0203360. doi: 10.1371/journal.pone.0203360. eCollection 2018.

Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis.  Zaiss DMW1, Coffer PJ2,3.  Nat Rev Immunol. 2018 Sep 3. doi: 10.1038/s41577-018-0048-9. [Epub ahead of print]

August 2018

The structure of a conserved telomeric region associated with variant antigen loci in the blood parasite Trypanosoma congolense.  Abbas AH1,2, Pereira SS3, D'Archivio S4, Wickstead B4, Morrison LJ5, Hall N6, Hertz-Fowler C1, Darby AC1, Jackson AP3.  Genome Biol Evol. 2018 Aug 25. doi: 10.1093/gbe/evy186. [Epub ahead of print]

Population genetics of benzimidazole-resistant Haemonchus contortus and Haemonchus placei from buffalo and cattle: implications for the emergence and spread of resistance mutations.  Ali Q1, Rashid I1, Shabbir MZ2, Shahzad K3, Ashraf K1, Sargison ND4, Chaudhry U5.  Parasitol Res. 2018 Aug 24. doi: 10.1007/s00436-018-6055-8. [Epub ahead of print]

Molecular epidemiology of methicillin-susceptible Staphylococcus aureus (MSSA) isolated from milk of cows with subclinical mastitis.  Bonsaglia ECR1, Silva NCC2, Rossi BF3, Camargo CH4, Dantas STA3, Langoni H5, Guimarães FF5, Lima FS6, Fitzgerald JR7, Fernandes A Júnior3, Rall VLM8.  Microb Pathog. 2018 Aug 20;124:130-135. doi: 10.1016/j.micpath.2018.08.031. [Epub ahead of print]

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken.  Bush SJ1,2, Freem L1, MacCallum AJ1, O'Dell J1,3, Wu C4, Afrasiabi C4, Psifidi A1,5, Stevens MP1, Smith J1, Summers KM1,6, Hume DA7,8.  BMC Genomics. 2018 Aug 7;19(1):594. doi: 10.1186/s12864-018-4972-7.

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens.  Clarke F1, Purvis HA2, Sanchez-Blanco C2, Gutiérrez-Martinez E2, Cornish GH2, Zamoyska R3, Guermonprez P2, Cope AP2.  Sci Rep. 2018 Aug 23;8(1):12692. doi: 10.1038/s41598-018-31179-x.

Sensors for Fetal Hypoxia and Metabolic Acidosis: A Review.  Cummins G1, Kremer J2, Bernassau A3, Brown A4, Bridle HL5, Schulze H6, Bachmann TT7, Crichton M8, Denison FC9, Desmulliez MPY10.  Sensors (Basel). 2018 Aug 13;18(8). pii: E2648. doi: 10.3390/s18082648.

Ubiquitous parasites drive a 33% increase in methane yield from livestock.  Fox NJ1, Smith LA2, Houdijk JGM1, Athanasiadou S1, Hutchings MR1.  Int J Parasitol. 2018 Aug 11. pii: S0020-7519(18)30172-3. doi: 10.1016/j.ijpara.2018.06.001. [Epub ahead of print]

Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity.  González-Fernández E1, Staderini M1, Yussof A1, Scholefield E2, Murray AF3, Mount AR4, Bradley M5.  Biosens Bioelectron. 2018 Nov 15;119:209-214. doi: 10.1016/j.bios.2018.08.013. Epub 2018 Aug 9.

The role of neutrophils in cancer.  Grecian R1, Whyte MKB1, Walmsley SR1.  Br Med Bull. 2018 Aug 22. doi: 10.1093/bmb/ldy029. [Epub ahead of print]

Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study.  He Y1,2,3, Timofeeva M1, Farrington SM1, Vaughan-Shaw P1, Svinti V1, Walker M1, Zgaga L1,4, Meng X3 et al.  BMC Med. 2018 Aug 14;16(1):142. doi: 10.1186/s12916-018-1119-2.

Delivery and evaluation of participatory education for animal keepers led by veterinarians and para-veterinarians around the Kanha Tiger Reserve, Madhya Pradesh, India.  Hopker A1, Pandey N2, Dhamorikar A2, Hopker S1, Gautam P2, Pandey S2, Kumar S2, Rahangadale N2, Mehta P2, Marsland R3, Sargison N1.  PLoS One. 2018 Aug 2;13(8):e0200999. doi: 10.1371/journal.pone.0200999. eCollection 2018.

Lawsonia intracellularis: Revisiting the Disease Ecology and Control of This Fastidious Pathogen in Pigs.  Karuppannan AK1, Opriessnig T1,2.  Front Vet Sci. 2018 Aug 9;5:181. doi: 10.3389/fvets.2018.00181. eCollection 2018.

The coumarin glucoside, esculin, reveals rapid changes in phloem-transport velocity in response to environmental cues.  Knox K1, Paterlini A2, Thomson S3, Oparka KJ4.  Plant Physiol. 2018 Aug 15. pii: pp.00574.2018. doi: 10.1104/pp.18.00574. [Epub ahead of print]

Probing the Spatiotemporal Dynamics of Catalytic Janus Particles with Single-Particle Tracking and Differential Dynamic Microscopy.  Kurzthaler C1, Devailly C2, Arlt J2, Franosch T1, Poon WCK2, Martinez VA2, Brown AT2.  Phys Rev Lett. 2018 Aug 17;121(7):078001. doi: 10.1103/PhysRevLett.121.078001.

The potential of small ruminant farming as a means of poverty alleviation in rural southern India. Lalljee SV1, Soundararajan C2, Singh YD3, Sargison ND4.  Trop Anim Health Prod. 2018 Aug 15. doi: 10.1007/s11250-018-1686-4. [Epub ahead of print]

Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites.  Loy DE1,2, Plenderleith LJ3,4, Sundararaman SA1,2, Liu W1, Gruszczyk J5, Chen YJ4,6, Trimboli S1, Learn GH1 et al.  Proc Natl Acad Sci U S A. 2018 Aug 20. pii: 201810053. doi: 10.1073/pnas.1810053115. [Epub ahead of print]

Electrodrugs: an electrochemical prodrug activation strategy.  Norman DJ1, González-Fernández E1, Clavadetscher J1, Tucker L1, Staderini M1, Mount AR1, Murray AF2, Bradley M1.  Chem Commun (Camb). 2018 Aug 1. doi: 10.1039/c8cc04151b. [Epub ahead of print]

Mapping and Sequencing of a Significant Quantitative Trait Locus Affecting Resistance to Koi Herpesvirus in Common Carp.  Palaiokostas C1, Robledo D2, Vesely T3, Prchal M4, Pokorova D3, Piackova V4, Pojezdal L3, Kocour M4, Houston RD2.  G3 (Bethesda). 2018 Aug 29. pii: g3.200593.2018. doi: 10.1534/g3.118.200593. [Epub ahead of print]

3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.  Rashidi H1, Luu NT2, Alwahsh SM1, Ginai M3, Alhaque S1, Dong H4, Tomaz RA5, Vernay B1, Vigneswara V2, Hallett JM1 et al.  Arch Toxicol. 2018 Aug 28. doi: 10.1007/s00204-018-2280-2. [Epub ahead of print]

Demonstration of the Anthelmintic potency of Marimastat in the Heligmosomoides Polygyrus Rodent Model.  Robertson E1, Harcus Y2, Johnston CJC3, Page AP4, Walkinshaw MD5, Maizels RM6, Houston D7,8.  J Parasitol. 2018 Aug 17. doi: 10.1645/18-33. [Epub ahead of print]

Gene Expression Response to Sea Lice in Atlantic Salmon Skin: RNA Sequencing Comparison Between Resistant and Susceptible Animals.  Robledo D1, Gutiérrez AP1, Barría A2, Yáñez JM2,3, Houston RD1.  Front Genet. 2018 Aug 3;9:287. doi: 10.3389/fgene.2018.00287. eCollection 2018.

Bovine telomere dynamics and the association between telomere length and productive lifespan.  Seeker LA1,2, Ilska JJ3, Psifidi A4,5, Wilbourn RV6, Underwood SL6, Fairlie J6, Holland R6, Froy H6, Salvo-Chirnside E7, Bagnall A8, Whitelaw B4, Coffey MP3, Nussey DH6, Banos G3,4.  Sci Rep. 2018 Aug 24;8(1):12748. doi: 10.1038/s41598-018-31185-z.

Orchestrating the proteome with post-translational modifications.  Spoel SH1.  J Exp Bot. 2018 Aug 31;69(19):4499-4503. doi: 10.1093/jxb/ery295.

Genome-wide scan of the effect of common nsSNPs on colorectal cancer survival outcome.  Theodoratou E1,2, Farrington SM2, Timofeeva M2, Din FV2, Svinti V2, Tenesa A3, Liu T4, Lindblom A4, Gallinger S5, Campbell H1,2, Dunlop MG6.  Br J Cancer. 2018 Aug 21. doi: 10.1038/s41416-018-0117-7. [Epub ahead of print]

July 2018

Sporadic Fatal Insomnia in Europe: Phenotypic features and diagnostic challenges.  Abu-Rumeileh S1, Redaelli V2, Baiardi S1, Mackenzie G3, Windl O4, Ritchie DL3, Didato G5, Hernandez-Vara J6, Rossi M7 et al.  Ann Neurol. 2018 Jul 26. doi: 10.1002/ana.25300. [Epub ahead of print]

Colonization of a commercial broiler line by Campylobacter is under limited genetic control and does not significantly impair performance or intestinal health.  Bailey RA1, Kranis A1, Psifidi A2,3, Watson KA1,2, Rothwell L2, Hocking PM2, Kaiser P2, Stevens MP2, Avendano S1.  Poult Sci. 2018 Jul 5. doi: 10.3382/ps/pey295. [Epub ahead of print]

Comparative MHC nomenclature: report from the ISAG/IUIS-VIC committee 2018.  Ballingall KT1, Bontrop RE2, Ellis SA3, Grimholt U4, Hammond JA3, Ho CS5, Kaufman J6, Kennedy LJ7, Maccari G3,8, Miller D9, Robinson J8,10, Marsh SGE8,10.  Immunogenetics. 2018 Jul 24. doi: 10.1007/s00251-018-1073-3. [Epub ahead of print]

Detection of potentially human infectious assemblages of Giardia duodenalis in fecal samples from beef and dairy cattle in Scotland.  Bartley PM1, Roehe BK1, Thomson S1, Shaw HJ1, Peto F1, Innes EA1, Katzer F1.  Parasitology. 2018 Jul 6:1-8. doi: 10.1017/S0031182018001117. [Epub ahead of print].

Human skin commensals augment Staphylococcus aureus pathogenesis.  Boldock E1,2,3, Surewaard BGJ4,5, Shamarina D1,2, Na M6, Fei Y6,7, Ali A6, Williams A2, Pollitt EJG2, Szkuta P2, Morris P1,3 et al.  Nat Microbiol. 2018 Jul 16. doi: 10.1038/s41564-018-0198-3. [Epub ahead of print]

Diagnosis of Methionine/Valine Variant Creutzfeldt-Jakob Disease by Protein Misfolding Cyclic Amplification.  Bougard D, Bélondrade M, Mayran C, Bruyère-Ostells L, Lehmann S, Fournier-Wirth C, Knight RS, Will RG, Green AJE.  Emerg Infect Dis. 2018 Jul;24(7):1364-1366. doi: 10.3201/eid2407.172105.

Progress and Remaining Gaps in Estimating the Global Disease Burden of Influenza.  Bresee J, Fitzner J, Campbell H, Cohen C, Cozza V, Jara J, Krishnan A, Lee V; WHO Working Group on the Burden of Influenza Disease.  Emerg Infect Dis. 2018 Jul;24(7):1173-1177. doi: 10.3201/eid2407.171270.

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157.  Cowley LA1,2, Low AS3, Pickard D4, Boinett CJ4,5, Dallman TJ6, Day M6, Perry N6, Gally DL3, Parkhill J4, Jenkins C6, Cain AK4,7.  MBio. 2018 Jul 24;9(4). pii: e00705-18. doi: 10.1128/mBio.00705-18. 

Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.  Dewar CE1, MacGregor P1, Cooper S1, Gould MK1, Matthews KR1, Savill NJ1, Schnaufer A1.  PLoS Pathog. 2018 Jul 18;14(7):e1007195. doi: 10.1371/journal.ppat.1007195. [Epub ahead of print]

Development of in vitro enteroids derived from bovine small intestinal crypts.  Hamilton CA1, Young R1, Jayaraman S1, Sehgal A1,2, Paxton E1, Thomson S3, Katzer F3, Hope J1, Innes E3, Morrison LJ4, Mabbott NA5.  Vet Res. 2018 Jul 3;49(1):54. doi: 10.1186/s13567-018-0547-5.

Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures.  Krstajić N1,2,3, Mills B1, Murray I1, Marshall A1, Norberg D1, Craven TH1, Emanuel P1, Choudhary TR1,4, Williams GOS1, Scholefield E1,  J Biomed Opt. 2018 Jul;23(7):1-12. doi: 10.1117/1.JBO.23.7.076005.

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.  Lee JJ1, Wedow R2,3,4, Okbay A5,6, Kong E7, Maghzian O7, Zacher M8, Nguyen-Viet TA9, Bowers P7, Sidorenko J10,11 et al.  Nat Genet. 2018 Jul 23. doi: 10.1038/s41588-018-0147-3. [Epub ahead of print]

Geostatistical models using remotely-sensed data predict savanna tsetse decline across the interface between protected and unprotected areas in Serengeti, Tanzania.  Lord JS1, Torr SJ1, Auty HK2, Brock PM3, Byamungu M4, Hargrove JW5, Morrison LJ6, Mramba F4, Vale GA5,7, Stanton MC1.  J Appl Ecol. 2018 Jul;55(4):1997-2007. doi: 10.1111/1365-2664.13091. Epub 2018 Feb 13.

IPD-MHC: nomenclature requirements for the non-human major histocompatibility complex in the next-generation sequencing era.  Maccari G1,2, Robinson J2,3, Bontrop RE4, Otting N4, de Groot NG4, Ho CS5, Ballingall KT6, Marsh SGE2,3, Hammond JA7.  Immunogenetics. 2018 Jul 19. doi: 10.1007/s00251-018-1072-4. [Epub ahead of print]

Oral prion neuroinvasion occurs independently of PrPC expression in the gut epithelium.  Marshall A1, Bradford BM1, Clarke AR2, Manson JC3, Mabbott NA4.  J Virol. 2018 Jul 18. pii: JVI.01010-18. doi: 10.1128/JVI.01010-18. [Epub ahead of print]

Worms: Pernicious Parasites or Allies Against Allergies?  McSorley HJ1, Chayé MAM2, Smits HH2.  Parasite Immunol. 2018 Jul 25:e12574. doi: 10.1111/pim.12574. [Epub ahead of print]

Haemolysis and haem oxygenase-1 induction during persistent "asymptomatic" malaria infection in Burkinabé children.  Mooney JP1,2, Barry A3, Gonçalves BP4, Tiono AB3, Awandu SS5, Grignard L4, Drakeley CJ4, Bottomley C6, Bousema T5, Riley EM4,7.  Malar J. 2018 Jul 6;17(1):253. doi: 10.1186/s12936-018-2402-6.

An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017).  O'Halloran C1, Hope JC1, Dobromylskyj M2, Burr P3, McDonald K3, Rhodes S4, Roberts T4, Dampney R4, De la Rua-Domenech R4, Robinson N4, Gunn-Moore DA1.  Transbound Emerg Dis. 2018 Jul 30. doi: 10.1111/tbed.12969. [Epub ahead of print]

Universal Health Coverage in Africa: Coinfections and Comorbidities.  Osakunor DNM1, Sengeh DM2, Mutapi F3.  Trends Parasitol. 2018 Jul 26. pii: S1471-4922(18)30140-5. doi: 10.1016/j.pt.2018.07.002. [Epub ahead of print]

Meningococcal carriage in high-risk settings: A systematic review.  Peterson ME1, Mile R2, Li Y2, Nair H2, Kyaw MH3.  Int J Infect Dis. 2018 Jul 2. pii: S1201-9712(18)34432-1. doi: 10.1016/j.ijid.2018.05.022. [Epub ahead of print]

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.  Phadwal K1, Kurian D1, Salamat MKF1, MacRae VE1, Diack AB1, Manson JC2,3,4.  Sci Rep. 2018 Jul 3;8(1):10004. doi: 10.1038/s41598-018-28296-y.

Analysis of temporal fecal microbiota dynamics in weaner pigs with and without exposure to enterotoxigenic Escherichia coli.  Pollock J1,2, Gally DL2, Glendinning L2, Tiwari R3, Hutchings MR1, Houdijk JGM1.  J Anim Sci. 2018 Jul 3. doi: 10.1093/jas/sky260. [Epub ahead of print]

Gene exchange drives the ecological success of a multi-host bacterial pathogen.  Richardson EJ1,2, Bacigalupe R1, Harrison EM3, Weinert LA4, Lycett S1, Vrieling M1, Robb K5, Hoskisson PA5, Holden MTG6, Feil EJ7 et al.  Nat Ecol Evol. 2018 Jul 23. doi: 10.1038/s41559-018-0617-0. [Epub ahead of print]

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses.  Sanchez-Blanco C1, Clarke F1, Cornish GH1, Depoil D2, Thompson SJ1, Dai X3, Rawlings DJ3, Dustin ML2, Zamoyska R4, Cope AP1, Purvis HA5.  J Autoimmun. 2018 Jul 24. pii: S0896-8411(18)30299-3. doi: 10.1016/j.jaut.2018.07.008. [Epub ahead of print]

Global Burden of Atherosclerotic Cardiovascular Disease in People Living with the Human Immunodeficiency Virus: A Systematic Review and Meta-Analysis.  Shah ASV1, Stelzle D2, Lee KK3, Beck EJ4, Alam S3, Clifford S3, Longenecker CT5, Strachan FE3, Bagchi S6, Whiteley W7 et al. Circulation. 2018 Jul 2. pii: CIRCULATIONAHA.117.033369. doi: 10.1161/CIRCULATIONAHA.117.033369. [Epub ahead of print]

Population genomics of bacterial host adaptation.  Sheppard SK1, Guttman DS2,3, Fitzgerald JR4.  Nat Rev Genet. 2018 Jul 4. doi: 10.1038/s41576-018-0032-z. [Epub ahead of print]

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.  van Setten J1, Brody JA2, Jamshidi Y3, Swenson BR2,4, Butler AM5, Campbell H6, Del Greco FM7, Evans DS8, Gibson Q9 et al.  Nat Commun. 2018 Jul 25;9(1):2904. doi: 10.1038/s41467-018-04766-9.

Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000-15.  Wahl B1, O'Brien KL2, Greenbaum A2, Majumder A2, Liu L3, Chu Y4, Lukšić I5, Nair H6, McAllister DA7, Campbell H8, Rudan I8, Black R4, Knoll MD2.   Lancet Glob Health. 2018 Jul;6(7):e744-e757. doi: 10.1016/S2214-109X(18)30247-X.

Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes.  Waldron FM1, Stone GN1, Obbard DJ1,2.  PLoS Genet. 2018 Jul 30;14(7):e1007533. doi: 10.1371/journal.pgen.1007533. [Epub ahead of print]

Loss of NLRP3 function alleviates murine hepatic graft-versus-host disease.  Zhu S1, Shi P2, Lv C2, Li H2, Pan B1, Chen W1, Zhao K1, Yan Z1, Chen C1, Loake GJ3, Niu M1, Zeng L1, Xu K4.  Biol Blood Marrow Transplant. 2018 Jul 24. pii: S1083-8791(18)30415-4. doi: 10.1016/j.bbmt.2018.07.026. [Epub ahead of print]

June 2018

The Ubiquitin-proteasome System as a Regulator of Plant Immunity.  Adams EHG1, Spoel SH1.  J Exp Bot. 2018 Jun 5. doi: 10.1093/jxb/ery216. [Epub ahead of print]

Increased susceptibility to oral Trichuris muris infection in the specific absence of CXCR5+ CD11c+ cells.  Bradford BM1, Donaldson DS1, Forman R2, Else KJ2, Mabbott NA1.  Parasite Immunol. 2018 Jun 19:e12566. doi: 10.1111/pim.12566. [Epub ahead of print]

Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution.  Bräuer KE1, Brockers K1, Moneer J2, Feuchtinger A3, Wollscheid-Lengeling E4, Lengeling A4,5, Wolf A6.  BMC Evol Biol. 2018 Jun 19;18(1):96. doi: 10.1186/s12862-018-1215-0.

Pigs lacking the scavenger receptor cysteine-rich domain 5 of CD163 are resistant to PRRSV-1 infection.  Burkard C1, Opriessnig T2,3, Mileham AJ4, Stadejek T5, Ait-Ali T2, Lillico SG2, Whitelaw CBA2, Archibald AL2.  J Virol. 2018 Jun 20. pii: JVI.00415-18. doi: 10.1128/JVI.00415-18. [Epub ahead of print]

Development of an evidence-based brief 'talking' intervention for non-responders to bowel screening for use in primary care: stakeholder interviews.  Cavers D1, Calanzani N2, Orbell S3, Vojt G4, Steele RJC5, Brownlee L6, Smith S7, Patnick J8, Weller D2, Campbell C2.  BMC Fam Pract. 2018 Jun 30;19(1):105. doi: 10.1186/s12875-018-0794-6.

Purification of Microprocessor-Associated Factors.  Cordiner RA1, Macias S2.  Methods Mol Biol. 2018;1823:51-62. doi: 10.1007/978-1-4939-8624-8_5.

A Microelectrode Array with Reproducible Performance Shows Loss of Consistency Following Functionalization with a Self-Assembled 6-Mercapto-1-hexanol Layer.  Corrigan DK1,2, Vezza V3, Schulze H4, Bachmann TT5, Mount AR6, Walton AJ7, Terry JG8.  Sensors (Basel). 2018 Jun 9;18(6). pii: E1891. doi: 10.3390/s18061891.

Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak.  Dellicour S1, Baele G2, Dudas G3, Faria NR4, Pybus OG4, Suchard MA5,6,7, Rambaut A8,9, Lemey P2.  Nat Commun. 2018 Jun 8;9(1):2222. doi: 10.1038/s41467-018-03763-2.

Mitogenome phylogeographic analysis of a planktonic crustacean.  Fields PD1, Obbard DJ2, McTaggart SJ2, Galimov Y3, Little TJ2, Ebert D4.  Mol Phylogenet Evol. 2018 Jun 16. pii: S1055-7903(17)30918-1. doi: 10.1016/j.ympev.2018.06.028. [Epub ahead of print]

Counterintuitive increase in observed Mycobacterium avium subspecies paratuberculosis prevalence in sympatric rabbits following the introduction of paratuberculosis control measures in cattle.  Fox NJ1, Caldow GL1, Liebeschuetz H2, Stevenson K3, Hutchings MR1.  Vet Rec. 2018 Jun 2;182(22):634. doi: 10.1136/vr.104638. Epub 2018 Feb 14.

Use of the Litomosoides sigmodontis Infection Model of Filariasis to Study Type 2 Immunity.  Fulton A1,2, Babayan SA3, Taylor MD4,5,6.  Methods Mol Biol. 2018 Jun 28  2018;1799:11-26. doi: 10.1007/978-1-4939-7896-0_2.

Erysipelothrix rhusiopathiae serotype 15 associated with recurring pig erysipelas outbreaks.  Gerber PF1,2, MacLeod A3, Opriessnig T1,4.  Vet Rec. 2018 Jun 2;182(22):635. doi: 10.1136/vr.104421. Epub 2018 Mar 8.

The cellular and pathologic prion protein.  Gill AC1, Castle AR2.  Handb Clin Neurol. 7 June 2018;153:21-44. doi: 10.1016/B978-0-444-63945-5.00002-7.

The impact of acute air pollution fluctuations on bronchiectasis pulmonary exacerbation. A case-crossover analysis.  Goeminne CP1,2, Cox B3, Finch S4, Loebinger MR5, Bedi P6, Hill AT7, Fardon TC4, de Hoogh K8,9, Nawrot TS3,10, Chalmers JD4.  Eur Respir J. 2018 Jun 14. pii: 1702557. doi: 10.1183/13993003.02557-2017. [Epub ahead of print]

Classic and atypical scrapie - a genetic perspective.  Goldmann W1.  Handb Clin Neurol.  7 June 2018;153:111-120. doi: 10.1016/B978-0-444-63945-5.00006-4.

Lack of efficacy of monepantel against trichostrongyle nematodes in a UK sheep flock.  Hamer K1, Bartley D2, Jennings A1, Morrison A2, Sargison N3.  Vet Parasitol. 2018 Jun 15;257:48-53. doi: 10.1016/j.vetpar.2018.05.013. Epub 2018 Jun 1.

Sphingolipid biosynthesis in man and microbes.  Harrison PJ1, Dunn TM2, Campopiano DJ1.  Nat Prod Rep. 2018 Jun 4. doi: 10.1039/c8np00019k. [Epub ahead of print]

High sample throughput genotyping for estimating C-lineage introgression in the dark honeybee: an accurate and cost-effective SNP-based tool.  Henriques D1,2, Browne KA3, Barnett MW4, Parejo M5, Kryger P6, Freeman TC4, Muñoz I7, Garnery L8,9, Highet F10, Jonhston JS11, McCormack GP3, Pinto MA12.  Sci Rep. 2018 Jun 4;8(1):8552. doi: 10.1038/s41598-018-26932-1.

Pandemics: spend on surveillance, not prediction.   Holmes EC, Rambaut A, Andersen KG.  Nature. 2018 Jun;558(7709):180-182. doi: 10.1038/d41586-018-05373-w.

Cerebral Concussion Primes the Lungs for Subsequent Neutrophil-Mediated Injury.  Humphries DC1, O'Neill S1, Scholefield E1, Dorward DA1, Mackinnon AC1, Rossi AG1, Haslett C1, Andrews PJD2, Rhodes J3, Dhaliwal K1.  Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003270. [Epub ahead of print]

Tsetse fly evolution, genetics and the trypanosomiases - A review.  Krafsur ES1, Maudlin I2.  Infect Genet Evol. 2018 Jun 6. pii: S1567-1348(18)30342-3. doi: 10.1016/j.meegid.2018.05.033. [Epub ahead of print]

The role of the immune system in prion infection.  Mabbott NA1, Alibhai JD2, Manson J3.  Handb Clin Neurol. 2018;153:85-107. doi: 10.1016/B978-0-444-63945-5.00005-2.

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation.  Marwick JA1, Mills R2, Kay O2, Michail K2, Stephen J3, Rossi AG2, Dransfield I2, Hirani N2.  Cell Death Dis. 2018 Jun 4;9(6):665. doi: 10.1038/s41419-018-0710-y.

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.   Mazur NI1, Higgins D2, Nunes MC3, Melero JA4, Langedijk AC5, Horsley N6, Buchholz UJ7, Openshaw PJ8, McLellan JS9, Englund JA10, Mejias A11 et al.  Lancet Infect Dis. 2018 Jun 15. pii: S1473-3099(18)30292-5. doi: 10.1016/S1473-3099(18)30292-5. [Epub ahead of print]

Identification of Host Factors Involved in Human Cytomegalovirus Replication, Assembly, and Egress Using a Two-Step Small Interfering RNA Screen.  McCormick D#1, Lin YT#1, Grey F2.  MBio. 2018 Jun 26;9(3). pii: e00716-18. doi: 10.1128/mBio.00716-18.

Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.  McDonald L1, Cayla M1, Ivens A1, Mony B1, MacGregor P1, Silvester E1, McWilliam K1, Matthews KR1.  PLoS Pathog. 2018 Jun 25;14(6):e1007145. doi: 10.1371/journal.ppat.1007145. [Epub ahead of print]

Squamous cell carcinoma in the anophthalmic socket: a series of four cases with HPV-16 profiling.  McGrath LA1,2, Salvi SM2, Sandramouli S3, Bhatt R3, Cuschieri K4, Mudhar HS5.  Br J Ophthalmol. 2018 Jun 28. pii: bjophthalmol-2018-311916. doi: 10.1136/bjophthalmol-2018-311916. [Epub ahead of print]

Detection of Norovirus by BD MAX™, Xpert® Norovirus, and xTAG® Gastrointestinal Pathogen Panel in stool and vomit samples.  McHugh MP1, Guerendiain D1, Hardie A1, Kenicer J1, MacKenzie L1, Templeton KE2.  J Clin Virol. 2018 Jun 8;105:72-76. doi: 10.1016/j.jcv.2018.06.005. [Epub ahead of print]

Mapping macrophage polarization over the myocardial infarction time continuum.  Mouton AJ1, DeLeon-Pennell KY1,2, Rivera Gonzalez OJ1, Flynn ER1, Freeman TC3, Saucerman JJ4, Garrett MR5, Ma Y1, Harmancey R1, Lindsey ML6,7.  Basic Res Cardiol. 2018 Jun 4;113(4):26. doi: 10.1007/s00395-018-0686-x.

Mandibular Sequamous Cell Carcinoma in a rock hyrax (Procavia Capensis).  Naylor AD, Morrison LR, Girling SJ, ZooMed D.  J Zoo Wildl Med. 2018 Jun;49(2):489-492. doi: 10.1638/2017-0220.1.

Suspected Hypovitaminosis A-Associated salt gland adenitis in northern Rockhopper Penguins (Eudyptes Moseleyi).  Naylor AD, Pizzi R, Cole G, Morrison LR, Girling SJ.  J Zoo Wildl Med. 2018 Jun;49(2):420-428. doi: 10.1638/2017-0219.1.

Clinical Signs, Antemortem Diagnostics, and Pathological findings associated with Mycobacterium Avium Subspecies Paratuberculosis Infection in Mishmi Takin ( BUDORCAS TAXICOLOR TAXICOLOR). Naylor AD, Richardson D, Sellar M, Harley J, Philbey AW, Girling SJ.  J Zoo Wildl Med. 2018 Jun;49(2):412-419. doi: 10.1638/2017-0215.1.

Genome-wide association and genomic prediction of resistance to viral nervous necrosis in European sea bass (Dicentrarchus labrax) using RAD sequencing.  Palaiokostas C1, Cariou S2, Bestin A3, Bruant JS2, Haffray P3, Morin T4, Cabon J4, Allal F5, Vandeputte M6, Houston RD7.  Genet Sel Evol. 2018 Jun 8;50(1):30. doi: 10.1186/s12711-018-0401-2.

Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses.  Palmer WH1, Medd NC1, Beard PM2, Obbard DJ1,3.  PLoS Pathog. 2018 Jun 4;14(6):e1007050. doi: 10.1371/journal.ppat.1007050. [Epub ahead of print]

Microbial diversity and community composition of caecal microbiota in commercial and indigenous Indian chickens determined using 16s rDNA amplicon sequencing.  Pandit RJ1, Hinsu AT2, Patel NV1, Koringa PG1, Jakhesara SJ1, Thakkar JR1, Shah TM1, Limon G3, et al.  Microbiome. 2018 Jun 23;6(1):115. doi: 10.1186/s40168-018-0501-9.

Uptake of HCV treatment in HIV/HCV coinfected patients across europe in the era of direct-acting antivirals.  Peters L1, Laut K1, Resnati C2, Del Campo S3, Leen C4, Falconer K5, Trofimova T6, Paduta D7, Gatell J8, Rauch A9, Lacombe K10, Domingo P11 et al.  AIDS. 2018 Jun 14. doi: 10.1097/QAD.0000000000001928. [Epub ahead of print]

Malaria Makes the Most of Mealtimes.  Reece SE1, Prior KF2.  Cell Host Microbe. 2018 Jun 13;23(6):695-697. doi: 10.1016/j.chom.2018.05.015.

Premature Rejection of Plasticity in Conversion.  Reece SE1, Schneider P2.  Trends Parasitol. 2018 Jun 23. pii: S1471-4922(18)30124-7. doi: 10.1016/j.pt.2018.06.004. [Epub ahead of print].

Pharmacological inhibition of the vacuolar ATPase in bloodstream form Trypanosoma brucei rescues genetic knockdown of mitochondrial gene expression.  Schaffner-Barbero C1, Miskinyte M1, Grewal JS2, Schnaufer A3.  Antimicrob Agents Chemother. 2018 Jun 18. pii: AAC.02268-17. doi: 10.1128/AAC.02268-17. [Epub ahead of print]

Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10.  Suchard MA1,2,3, Lemey P4, Baele G4, Ayres DL5, Drummond AJ6,7, Rambaut A8.  Virus Evol. 2018 Jun 8;4(1):vey016. doi: 10.1093/ve/vey016. eCollection 2018 Jan.

Phenotypic Switching Can Speed up Microbial Evolution.  Tadrowski AC1, Evans MR2, Waclaw B3,4.  Sci Rep. 2018 Jun 12;8(1):8941. doi: 10.1038/s41598-018-27095-9.

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.  Tedja MS1,2, Wojciechowski R3,4,5, Hysi PG6, Eriksson N7, Furlotte NA7, Verhoeven VJM1,2,8, Iglesias AI1,2,8, Meester-Smoor MA1,2, Tompson SW9 et al.  Nat Genet. 2018 Jun;50(6):834-848. doi: 10.1038/s41588-018-0127-7. Epub 2018 May 28.

Evaluation of Staphylococcus aureus eradication therapy in orthopaedic surgery.  Tsang STJ1,2, McHugh MP3, Guerendiain D3, Gwynne P1, Boyd J4, Laurenson IF3, Templeton KE3, Lewis S5, Simpson AHRW2, Walsh TS4.  J Med Microbiol. 2018 Jun;67(6):893-901. doi: 10.1099/jmm.0.000731. Epub 2018 Apr 19.

Inhibition of Microprocessor Function during the Activation of the Type I Interferon Response.  Witteveldt J1, Ivens A1, Macias S2.  Cell Rep. 2018 Jun 12;23(11):3275-3285. doi: 10.1016/j.celrep.2018.05.049.

Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment.  Xintaropoulou C1, Ward C1,2, Wise A3, Queckborner S1, Turnbull A1, Michie CO4, Williams ARW5, Rye T4, Gourley C4, Langdon SP6.  BMC Cancer. 2018 Jun 5;18(1):636. doi: 10.1186/s12885-018-4521-4.

May 2018

First genetic evidence for the presence of the rumen fluke Paramphistomum epiclitum in Pakistan.  Ali Q1, Rashid I1, Shabbir MZ2, Akbar H1, Shahzad K3, Ashraf K1, Sargison N4, Chaudhry U5.  Parasitol Int. 2018 May 18;67(5):533-537. doi: 10.1016/j.parint.2018.05.005. [Epub ahead of print]

Isolation and Identification of Murine Serous Cavity Macrophages.  Bain CC1, Jenkins SJ2.  Methods Mol Biol. 2018;1784:51-67. doi: 10.1007/978-1-4939-7837-3_5.

Blood Neutrophils are Reprogrammed in Bronchiectasis.  Bedi P1, Davidson DJ2, McHugh BJ3, Rossi AG4, Hill AT5,3.  Am J Respir Crit Care Med. 2018 May 7. doi: 10.1164/rccm.201712-2423OC. [Epub ahead of print]

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD.  Boyapati RK1, Dorward DA1, Tamborska A1, Kalla R1, Ventham NT1, Doherty MK2, Whitfield PD2, Gray M1, Loane J3, Rossi AG1, Satsangi J4, Ho GT1,4.  Inflamm Bowel Dis. 2018 May 1. doi: 10.1093/ibd/izy095. [Epub ahead of print]

Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity.   Brown SM1, Bush SJ2, Summers KM3, Hume DA3, Lawrence AB4.  Behav Brain Res. 2018 Sep 17;350:6-15. doi: 10.1016/j.bbr.2018.05.015. Epub 2018 May 17.

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.  Crittenden S1, Cheyne A1, Adams A2, Forster T3, Robb CT1, Felton J1, Ho GT1, Ruckerl D4, Rossi AG1, Anderton SM1, Ghazal P3,5, Satsangi J2, Howie SE1, Yao C1.  Immunol Cell Biol. 2018 May 14. doi: 10.1111/imcb.12167. [Epub ahead of print]

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells.  Driedonks TAP1, van der Grein SG1, Ariyurek Y2,3, Buermans HPJ2,3, Jekel H1, Chow FWN4, Wauben MHM1, Buck AH4, 't Hoen PAC2,5, Nolte-'t Hoen ENM6.  Cell Mol Life Sci. 2018 May 28. doi: 10.1007/s00018-018-2842-8. [Epub ahead of print]

Apoptotic Tumor Cell-Derived Extracellular Vesicles as Important Regulators of the Onco-Regenerative Niche.  Gregory CD1, Dransfield I1.  Front Immunol. 2018 May 23;9:1111. doi: 10.3389/fimmu.2018.01111. eCollection 2018.

Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis.  Hamilton S1, McLean K2, Monaghan SJ3, McNair C3, Inglis NF2, McDonald H3, Adams S3, Richards R3, Roy W3, Smith P4, Bron J3, Nisbet AJ2, Knox D2.  Parasit Vectors. 2018 May 11;11(1):294. doi: 10.1186/s13071-018-2885-6.

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.  Hirota K1, Hashimoto M2, Ito Y3, Matsuura M3, Ito H4, Tanaka M2, Watanabe H5, Kondoh G5, Tanaka A6, Yasuda K6, Kopf M7, Potocnik AJ8, Stockinger B9, Sakaguchi N6, Sakaguchi S10.  Immunity. 2018 May 15. pii: S1074-7613(18)30146-8. doi: 10.1016/j.immuni.2018.04.009. [Epub ahead of print]

A Genomic Region Containing REC8 and RNF212B Is Associated with Individual Recombination Rate Variation in a Wild Population of Red Deer (Cervus elaphus).  Johnston SE1, Huisman J2, Pemberton JM2.  G3 (Bethesda). 2018 May 15. pii: g3.200063.2018. doi: 10.1534/g3.118.200063. [Epub ahead of print]

Evaluation of PCR primers targeting the groEL gene for the specific detection of Streptococcus agalactiae in the context of aquaculture.  Leigh WJ1,2, Zadoks RN1,2, Jaglarz A1, Costa JZ1, Foster G3, Thompson KD1.  J Appl Microbiol. 2018 May 22. doi: 10.1111/jam.13925. [Epub ahead of print]

An update on equine post-operative ileus: Definitions, pathophysiology and management.  Lisowski ZM1, Pirie RS1, Blikslager AT2, Lefebvre D1, Hume DA1,3, Hudson NPH1.  Equine Vet J. 2018 May;50(3):292-303. doi: 10.1111/evj.12801. Epub 2018 Jan 29.

Maxillary tooth growth in the adult male babirusa (genus Babyrousa).  Macdonald AA1, Shaw DJ2.  C R Biol. 2018 May 8. pii: S1631-0691(18)30079-9. doi: 10.1016/j.crvi.2018.04.002. [Epub ahead of print]

Immunohistochemical differentiation of reactive from malignant mesothelium as a diagnostic aid in canine pericardial disease.  Milne E1, Martinez Pereira Y1, Muir C2, Scase T2, Shaw DJ1, McGregor G1, Oldroyd L3, Scurrell E4, Martin M5, Devine C6, Hodgkiss-Geere H7.  J Small Anim Pract. 2018 May;59(5):261-271. doi: 10.1111/jsap.12830. Epub 2018 Apr 2.

Reply to Jiménez-Alonso et al., Schooling and Zhao, and Mortazavi: Further discussion on the immunological model of carcinogenesis.  Palmer S1,2, Albergante L3,4, Blackburn CC5, Newman TJ1,6.  Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4319-E4321. doi: 10.1073/pnas.1802809115. Epub 2018 Apr 18.

Tick bites and tick-transmitted diseases.  Rocchi M1, Dagleish M1, McInnes C1.  Vet Rec. 2018 May 26;182(21):609. doi: 10.1136/vr.k2264.

Diagnosis and prevention of RHVD2 infection.  Rocchi M1, Dagleish M1.  Vet Rec. 2018 May 26;182(21):604-605. doi: 10.1136/vr.k2313.

Global governance of antimicrobial resistance.  Rochford C1, Sridhar D2, Woods N1, Saleh Z1, Hartenstein L3, Ahlawat H3, Whiting E4, Dybul M5, Cars O6, Goosby E7, Cassels A8, Velasquez G9, Hoffman S10, Baris E11, Wadsworth J11, Gyansa-Lutterodt M12, Davies S13.  Lancet. 2018 May 19;391(10134):1976-1978. doi: 10.1016/S0140-6736(18)31117-6. Epub 2018 May 17.

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1.  Schmolka N1, Papotto PH2, Romero PV2, Amado T2, Enguita FJ2, Amorim A2, Rodrigues AF3,4, Gordon KE5, Coroadinha AS3,4, Boldin M6, Serre K2, Buck AH5, Gomes AQ1,7, Silva-Santos B1.  Sci Immunol. 2018 May 4;3(23). pii: eaao1392. doi: 10.1126/sciimmunol.aao1392.

Disappearing hemipelvis: Low grade osteosarcoma, an unusual and poorly described variant of Paget's Sarcoma.  Stevens JM1, Flower H2, Salter D1,2,3, Patton JT1.  J Orthop. 2018 May 7;15(2):571-577. doi: 10.1016/j.jor.2018.05.017. eCollection 2018 Jun. 

An evidence-based approach to assessing surgical versus clinical diagnosis of symptomatic endometriosis.  Taylor HS1, Adamson GD2, Diamond MP3, Goldstein SR4, Horne AW5, Missmer SA6,7, Snabes MC8, Surrey E9, Taylor RN10.  Int J Gynaecol Obstet. 2018 May 5. doi: 10.1002/ijgo.12521. [Epub ahead of print]

Specificity in Nitric Oxide Signalling.  Umbreen S1, Lubega J1, Cui B2,3, Pan Q2,3, Jiang J2,3, Loake GJ1,3.  J Exp Bot. 2018 May 15. doi: 10.1093/jxb/ery184. [Epub ahead of print]

Disease Tolerance: Linking Sickness Behaviours to Metabolism Helps Mitigate Malaria.  Vale PF1.  Curr Biol. 2018 May 21;28(10):R606-R607. doi: 10.1016/j.cub.2018.04.031.

Getting DAMP(s) Wets the Whistle for Neutrophil Recruitment.  Watts ER1, Walmsley SR2.  Immunity. 2018 May 15;48(5):846-848. doi: 10.1016/j.immuni.2018.04.027.

An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.  Yuan M1, McNae IW1, Chen Y1, Blackburn EA1, Wear MA1, Michels PAM1, Fothergill-Gilmore LA2, Hupp T3, Walkinshaw MD4.  Biochem J. 2018 May 10. pii: BCJ20180171. doi: 10.1042/BCJ20180171. [Epub ahead of print]

April 2018

Directed Actin Cytoskeleton Self Organization, Contractility and Motility.  Abokhrais IM1, Saunders PTK2, Denison FC1, Doust A1, Williams L3, Horne AW1,4.  Pilot Feasibility Stud. 2018 Apr 25;4:83. doi: 10.1186/s40814-018-0274-8. eCollection 2018.

Prevention of exacerbations in patients with stable non-cystic fibrosis bronchiectasis: a systematic review and meta-analysis of pharmacological and non-pharmacological therapies.  Abu Dabrh AM#1,2, Hill AT#3, Dobler CC1, Asi N1, Farah WH1, Haydour Q1, Wang Z1, Benkhadra K1,4, Prokop LJ5, Murad MH1.  BMJ Evid Based Med. 2018 Apr 20. pii: bmjebm-2018-110893. doi: 10.1136/bmjebm-2018-110893. [Epub ahead of print]

Host chemokine signature as a biomarker for the detection of pre-cancerous cervical lesions.  Bhatia R1, Kavanagh K2, Stewart J3, Moncur S3, Serrano I4, Cong D3, Cubie HA5, Haas JG4, Busby-Earle C6, Williams ARW6, Howie SEM#3, Cuschieri K#7.  Oncotarget. 2018 Apr 6;9(26):18548-18558. doi: 10.18632/oncotarget.24946. eCollection 2018 Apr 6. 

Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids.  Buckner MMC#1, Saw HTH#1, Osagie RN1, McNally A2, Ricci V1, Wand ME3, Woodford N4, Ivens A5, Webber MA1, Piddock LJV6.  MBio. 2018 Apr 24;9(2). pii: e02303-17. doi: 10.1128/mBio.02303-17.

Draft Genome Assembly of the Sheep Scab Mite, Psoroptes ovis.  Burgess STG1, Bartley K2, Marr EJ2, Wright HW2, Weaver RJ3, Prickett JC3, Hughes M4, Haldenby S4, Thi Le P5,6,7,8,9, Rombauts S5,6,7, Van Leeuwen T10, Van de Peer Y5,6,7,11, Nisbet AJ2.  Genome Announc. 2018 Apr 19;6(16). pii: e00265-18. doi: 10.1128/genomeA.00265-18.

Cross-species inference of long non-coding RNAs greatly expands the ruminant transcriptome.  Bush SJ1,2, Muriuki C3, McCulloch MEB3, Farquhar IL4, Clark EL3, Hume DA5,6. Genet Sel Evol. 2018 Apr 24;50(1):20. doi: 10.1186/s12711-018-0391-0.

Risk Factors for Avian Influenza H9 Infection of Chickens in Live Bird Retail Stalls of Lahore District, Pakistan 2009-2010.  Chaudhry M1,2, Rashid HB3, Angot A4, Thrusfield M5, Bronsvoort BMD6, Capua I4,7, Cattoli G4,8, Welburn SC9,10, Eisler MC11. Sci Rep. 2018 Apr 4;8(1):5634. doi: 10.1038/s41598-018-23895-1.

Declining home range area predicts reduced late-life survival in two wild ungulate populations.  Froy H1, Börger L2, Regan CE1, Morris A1, Morris S1, Pilkington JG1, Crawley MJ3, Clutton-Brock TH4, Pemberton JM1, Nussey DH1.  Ecol Lett. 2018 Apr 15. doi: 10.1111/ele.12965. [Epub ahead of print]

Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties.  Gur M1, Blackburn EA2, Ning J3, Narayan V3, Ball KL3, Walkinshaw MD2, Erman B4.  J Chem Phys. 2018 Apr 14;148(14):145101. doi: 10.1063/1.5019457.

Nitric Oxide Analyzer Quantification of Plant S-Nitrosothiols.  Hussain A1, Yun BW2, Loake GJ3.  Methods Mol Biol. 2018;1747:223-230. doi: 10.1007/978-1-4939-7695-9_17.

Rediscovering Bacteria through Single-Molecule Imaging in Living Cells.  Kapanidis AN1, Lepore A2, El Karoui M3.  Biophys J. 2018 Apr 18. pii: S0006-3495(18)30398-9. doi: 10.1016/j.bpj.2018.03.028. [Epub ahead of print]

Association of seasonal viral acute respiratory infection with pneumococcal disease: a systematic review of population-based studies.  Li Y1, Peterson ME1, Campbell H1, Nair H1.  BMJ Open. 2018 Apr 21;8(4):e019743. doi: 10.1136/bmjopen-2017-019743. 

A graphical and computational modeling platform for biological pathways.  Livigni A1, O'Hara L1,2, Polak ME3,4, Angus T1, Wright DW1, Smith LB2,5, Freeman TC1.  Nat Protoc. 2018 Apr;13(4):705-722. doi: 10.1038/nprot.2017.144. Epub 2018 Mar 15.

An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias.  Lynch RW1, Hawley CA1, Pellicoro A1, Bain CC1, Iredale JP1, Jenkins SJ1.  J Leukoc Biol. 2018 Apr 1. doi: 10.1002/JLB.1TA0517-169R. [Epub ahead of print]

The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids.  Marchese L1, Nascimento JF2, Damasceno FS3, Bringaud F4, Michels PAM5, Silber AM6.  Pathogens. 2018 Apr 1;7(2). pii: E36. doi: 10.3390/pathogens7020036.

The carbon chain-selective adenylation enzyme TamA: the missing link between fatty acid and pyrrole natural product biosynthesis.  Marchetti PM 1, Kelly V , Simpson JP , Ward M , Campopiano DJ .  Org Biomol Chem. 2018 Apr 18;16(15):2735-2740. doi: 10.1039/c8ob00441b.

Ribosome maturation by the endoribonuclease YbeY stabilises a type III secretion system transcript required for virulence of enterohemorrhagic Escherichia coli.  McAteer SP1, Sy BM2, Wong JL2, Tollervey D3, Gally DL4, Tree JJ2.  J Biol Chem. 2018 Apr 20. pii: jbc.RA117.000300. doi: 10.1074/jbc.RA117.000300. [Epub ahead of print]

Are Food Animals Responsible for Transfer of Antimicrobial-Resistant Escherichia coli or Their Resistance Determinants to Human Populations? A Systematic Review.  Muloi D1,2, Ward MJ2,3, Pedersen AB2, Fèvre EM4,5, Woolhouse MEJ1,2, van Bunnik BAD1,2.  Foodborne Pathog Dis. 2018 Apr 30. doi: 10.1089/fpd.2017.2411. [Epub ahead of print]

Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α+thalassaemia.  Opi DH#1,2, Swann O#2, Macharia A1, Uyoga S1, Band G3, Ndila CM1, Harrison EM4, Thera MA5, Kone AK5, Diallo DA5, Doumbo OK5, Lyke KE6, Plowe CV6, Moulds JM7, Shebbe M1, Mturi N1, Peshu N1, Maitland K1,8, Raza A2, Kwiatkowski DP3,9, Rockett KA3, Williams TN#1,8, Rowe JA#2.  Elife. 2018 Apr 25;7. pii: e31579. doi: 10.7554/eLife.31579.

The social sciences, humanities, and health.  Pickersgill M1, Chan S2, Haddow G2, Laurie G2, Sridhar D2, Sturdy S2, Cunningham-Burley S2.  Lancet. 2018 Apr 14;391(10129):1462-1463. doi: 10.1016/S0140-6736(18)30669-X.

Posterior summarisation in Bayesian phylogenetics using Tracer 1.7.  Rambaut A1, Drummond AJ2,3, Xie D2,3, Baele G4, Suchard MA5,6.  Syst Biol. 2018 Apr 27. doi: 10.1093/sysbio/syy032. [Epub ahead of print]

Public health significance of Campylobacter spp. colonisation of wild game pheasants (Phasianus colchicus) in Scotland.  Seguino A1, Chintoan-Uta C2, Smith SH2, Shaw DJ2.  Food Microbiol. 2018 Sep;74:163-170. doi: 10.1016/j.fm.2018.04.002. Epub 2018 Apr 7.

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche.  Sehgal A1, Donaldson DS1, Pridans C1,2, Sauter KA1, Hume DA1,2,3, Mabbott NA4.  Nat Commun. 2018 Mar 28;9(1):1272. doi: 10.1038/s41467-018-03638-6.

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction.  Thevaranjan N, Puchta A, Schulz C, Naidoo A, Szamosi JC, Verschoor CP, Loukov D, Schenck LP, Jury J, Foley KP, Schertzer JD, Larché MJ, Davidson DJ, Verdú EF, Surette MG, Bowdish DME.  Cell Host Microbe. 2018 Apr 11;23(4):570. doi: 10.1016/j.chom.2018.03.006.

Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets.  Travassos MA1, Niangaly A2, Bailey JA3, Ouattara A3, Coulibaly D2, Lyke KE3, Laurens MB3, Pablo J4, Jasinskas A4, Nakajima R4, Berry AA3, Adams M3, Jacob CG5, Pike A3, Takala-Harrison S3, Liang L4, Kouriba B2, Kone AK2, Rowe JA6, Moulds J7, Diallo DA2, Doumbo OK2, Thera MA2, Felgner PL4, Plowe CV8.  Sci Rep. 2018 Apr 19;8(1):6281. doi: 10.1038/s41598-018-24462-4.

An analysis of effects of heterozygosity in dairy cattle for bovine tuberculosis resistance.  Tsairidou S1, Allen AR2, Pong-Wong R1, McBride SH2, Wright DM3, Matika O1, Pooley CM1, McDowell SWJ2, Glass EJ1, Skuce RA2,3, Bishop SC1, Woolliams JA1.  Anim Genet. 2018 Apr;49(2):103-109. doi: 10.1111/age.12637. Epub 2018 Jan 24.

Evaluation of Staphylococcus aureus eradication therapy in orthopaedic surgery.  Tsang STJ1,2, McHugh MP3, Guerendiain D3, Gwynne P1, Boyd J4, Laurenson IF3, Templeton KE3, Lewis S5, Simpson AHRW2, Walsh TS4.  J Med Microbiol. 2018 Apr 19. doi: 10.1099/jmm.0.000731. [Epub ahead of print]

Bacteria as living patchy colloids: Phenotypic heterogeneity in surface adhesion.  Vissers T1, Brown AT1, Koumakis N1, Dawson A1, Hermes M1,2, Schwarz-Linek J1, Schofield AB1, French JM1,3, Koutsos V3, Arlt J1, Martinez VA1, Poon WCK1.  Sci Adv. 2018 Apr 27;4(4):eaao1170. doi: 10.1126/sciadv.aao1170. eCollection 2018 Apr.

Microbial host interactions and impaired wound healing in mice and humans: defining a role for BD14 and NOD2.  Williams H1, Campbell L1, Crompton RA1, Singh G1, McHugh BJ2, Davidson DJ2, McBain AJ3, Cruickshank SM4, Hardman MJ5.  J Invest Dermatol. 2018 Apr 30. pii: S0022-202X(18)31893-1. doi: 10.1016/j.jid.2018.04.014. [Epub ahead of print]

March 2018

Seasonality of helminth infection in wild red deer varies between individuals and between parasite taxa.  Albery GF1, Kenyon F2, Morris A1, Morris S1, Nussey DH1, Pemberton JM1.  Parasitology. 2018 Mar 9:1-11. doi: 10.1017/S0031182018000185. [Epub ahead of print]

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.  Baillie JK1,2,3, Bretherick A1, Haley CS1,4, Clohisey S1, Gray A5, Neyton LPA1, Barrett J6, Stahl EA7, Tenesa A1, Andersson R8 et al.  PLoS Comput Biol. 2018 Mar 1;14(3):e1005934. doi: 10.1371/journal.pcbi.1005934. eCollection 2018 Mar.

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.  Bewley MA1, Budd RC1,2, Ryan E3, Cole J1,2, Collini P1,2, Marshall J4, Kolsum U5 et al.  Am J Respir Crit Care Med. 2018 Mar 16. doi: 10.1164/rccm.201705-0903OC. [Epub ahead of print]

Regulation of autoimmune and anti-tumour T cell responses by PTPN22.  Brownlie RJ1, Zamoyska R2, Salmond RJ1.  Immunology. 2018 Mar 7. doi: 10.1111/imm.12919. [Epub ahead of print]

MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity.  Chu DKW1, Hui KPY1, Perera RAPM1, Miguel E2,3, Niemeyer D4, Zhao J5,6, Channappanavar R5 et al.  Proc Natl Acad Sci U S A. 2018 Mar 5. pii: 201718769. doi: 10.1073/pnas.1718769115. [Epub ahead of print]

Unexpected synergistic and antagonistic antibiotic activity against Staphylococcus biofilms.  Dall GF1,2,3, Tsang SJ2,3,4, Gwynne PJ2, MacKenzie SP4, Simpson AHRW3, Breusch SJ4, Gallagher MP2.  J Antimicrob Chemother. 2018 Mar 14. doi: 10.1093/jac/dky087. [Epub ahead of print]

Erysipelothrix rhusiopathiae serotype 15 associated with recurring pig erysipelas outbreaks.  Gerber PF1,2, MacLeod A3, Opriessnig T1,4.  Vet Rec. 2018 Mar 8. pii: vetrec-2017-104421. doi: 10.1136/vr.104421. [Epub ahead of print]

Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.  Hawley CA1, Rojo R2, Raper A2, Sauter KA2, Lisowski ZM2, Grabert K2, Bain CC1 et al.  J Immunol. 2018 Mar 15;200(6):2209-2223. doi: 10.4049/jimmunol.1701488. Epub 2018 Feb 12.

Quantification and decomposition of environment-selection relationships.  Hunter DC1, Pemberton JM2, Pilkington JG2, Morrissey MB1.  Evolution. 2018 Mar 8. doi: 10.1111/evo.13461. [Epub ahead of print]

45% of UK gynaecologists think chronic pelvic pain is managed badly.  Leow HW1, Szubert W1, Horne AW2.  Eur J Obstet Gynecol Reprod Biol. 2018 Mar 10. pii: S0301-2115(18)30109-X. doi: 10.1016/j.ejogrb.2018.03.014. [Epub ahead of print]

Recent and Rapid Transmission of HIV among People who Inject Drugs in Scotland Revealed through Phylogenetic Analysis.  Ragonnet-Cronin M1,2, Jackson C3, Bradley-Stewart A3, Aitken C3 et al.  J Infect Dis. 2018 Mar 13. doi: 10.1093/infdis/jiy130. [Epub ahead of print]

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus.  Smyth DJ1, Harcus Y2, White MPJ1, Gregory WF1, Nahler J3, Stephens I1 et al.  Int J Parasitol. 2018 Mar 3. pii: S0020-7519(18)30047-X. doi: 10.1016/j.ijpara.2017.12.004. [Epub ahead of print]

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.  Turner JD1, Pionnier N1, Furlong-Silva J1, Sjoberg H1, Cross S1, Halliday A1 et al.  PLoS Pathog. 2018 Mar 16;14(3):e1006949. doi: 10.1371/journal.ppat.1006949. [Epub ahead of print]

February 2018

New work from researchers in the School of Biological Sciences shows consistent association between short telomeres and increased mortality risk in birds, but also highlights the need for more research into other non-avian vertebrates.

The relationship between telomere length and mortality risk in non-model vertebrate systems: a meta-analysis.  Wilbourn RV1, Moatt JP1, Froy H1, Walling CA1, Nussey DH2, Boonekamp JJ3.  Philos Trans R Soc Lond B Biol Sci. 2018 Mar 5;373(1741). pii: 20160447. doi: 10.1098/rstb.2016.0447.

New paper from Francisca Mutapi on the challenges still facing attempts to treat and prevent bilharzia - Schistosomiasis - in children

Paediatric schistosomiasis: What we know and what we need to know.  Osakunor DNM1, Woolhouse MEJ2,3, Mutapi F1,3.  PLoS Negl Trop Dis. 2018 Feb 8;12(2):e0006144. doi: 10.1371/journal.pntd.0006144. eCollection 2018 Feb.

New work from colleagues at the Moredun Research Institute explores how infction with liver flukes may affect shedding of pathogenic E. coli O157 in British cows.

Co-infection with Fasciola hepatica may increase the risk of Escherichia coli O157 shedding in British cattle destined for the food chain.D134  Howell AK1, Tongue SC2, Currie C3, Evans J2, Williams DJL4, McNeilly TN3.  Prev Vet Med. 2018 Feb 1;150:70-76. doi: 10.1016/j.prevetmed.2017.12.007. Epub 2017 Dec 7.

Research from Sue Welburn has helped to model the seasonal beahviour of the tsetse fly vector of human African Trypanosomiasis - essential for the development of appropriate, well-targeted mitigation strategies in the future

An agent-based model of tsetse fly response to seasonal climatic drivers: Assessing the impact on sleeping sickness transmission rates.  Alderton S1,2,3, Macleod ET4, Anderson NE5, Palmer G6, Machila N4,7, Simuunza M7, Welburn SC4, Atkinson PM1,2,3,8,9.  PLoS Negl Trop Dis. 2018 Feb 9;12(2):e0006188. doi: 10.1371/journal.pntd.0006188. eCollection 2018 Feb.

Work from colleagues in the Centre for Inflammation Research shows that augmenting  apoptotic  cell  clearance  is a potential  therapeutic  strategy  for treating allergic inflammation. 

Mer-mediated eosinophil efferocytosis regulates resolution of allergic airway inflammation.  Felton JM1, Lucas CD2, Dorward DA1, Duffin R1, Kipari T1, Vermeren S1, Robb CT1, MacLeod KG3, Serrels B3, Schwarze J1, Haslett C1, Dransfield I1, Rossi AG1.  J Allergy Clin Immunol. 2018 Feb 8. pii: S0091-6749(18)30215-X. doi: 10.1016/j.jaci.2018.01.029. [Epub ahead of print]

New paper from Sarah Reece's lab studying malaria parasite infection in mice shows that the time a host feeding time controls parasite replication rhythms - broad implications for host-parasite-vector coevolution.

Timing of host feeding drives rhythms in parasite replication.  Prior KF1, van der Veen DR2, O'Donnell AJ1, Cumnock K3, Schneider D3, Pain A4, Subudhi A4, Ramaprasad A4, Rund SSC5, Savill NJ1,5, Reece SE1,5.  PLoS Pathog. 2018 Feb 26;14(2):e1006900. doi: 10.1371/journal.ppat.1006900. [Epub ahead of print]

New work from colleagues in the Centre for Reproductive Health and the Moredun Research Institute shows how infection with Chlamydia predisposes women to ectopic pregnancy.

Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment.  Ahmad SF1, Brown JK1, Campbell LL1, Koscielniak M1, Oliver C1, Wheelhouse N2, Entrican G3, McFee S1, Wills GS4, McClure MO4, Horner PJ5, Gaikoumelou S1, Lee KF6, Critchley HOD1, Duncan WC1, Horne AW7.  EBioMedicine. 2018 Feb 23. pii: S2352-3964(18)30074-4. doi: 10.1016/j.ebiom.2018.02.020. [Epub ahead of print]

New paper from Ross Fitzgerald and colleagues reviews the role of "filth flies" in spreading antimicrobial resistance and argues for need to refine current risk assessment models.

The role of 'filth flies' in the spread of antimicrobial resistance.  Onwugamba FC1, Fitzgerald JR2, Rochon K3, Guardabassi L4, Alabi A5, Kühne S6, Grobusch MP7, Schaumburg F8.  Travel Med Infect Dis. 2018 Feb 26. pii: S1477-8939(18)30037-1. doi: 10.1016/j.tmaid.2018.02.007. [Epub ahead of print]

New study in rodents and bats in Vietnam finds wide circulation of diverse pegivirus and human hepatitis-related viruses - need better understanding of zoonotic potential and risk to human health

Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam.  Van Nguyen D1, Van Nguyen C2, Bonsall D3, Ngo TT4, Carrique-Mas J5,6, Pham AH7, Bryant JE8, Thwaites G9,10, Baker S11,12,13, Woolhouse M14, Simmonds P15.  Viruses. 2018 Feb 28;10(3). pii: E102. doi: 10.3390/v10030102.

January 2018

New study explores how IL-4-activated macrophages contribute to diverse outcomes during infection with filarial nematodes

Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection.  Campbell SM1, Knipper JA1, Ruckerl D1,2, Finlay CM2, Logan N1, Minutti CM1, Mack M3, Jenkins SJ4, Taylor MD1, Allen JE1,2.  Elife. 2018 Jan 4;7. pii: e30947. doi: 10.7554/eLife.30947.

New study from colleagues at the Royal Infirmary of Edinburgh shows one third of MRSA carrier are missed using standard culturing techniques

Underestimation of Staphylococcus aureus (MRSA and MSSA) carriage associated with standard culturing techniques: One third of carriers missed. Tsang STJ1, McHugh MP2, Guerendiain D2, Gwynne PJ3, Boyd J4, Simpson AHRW5, Walsh TS6, Laurenson IF2, Templeton KE2.  Bone Joint Res. 2018 Jan;7(1):79-84. doi: 10.1302/2046-3758.71.BJR-2017-0175.R1.

New analysis by colleagues at the Roslin Institute reviews the mechanisms used by bacteria to directly affect the T cell immune response and how these may contribute to pathogenesis

Direct manipulation of T lymphocytes by proteins of gastrointestinal bacterial pathogens.  Cassady-Cain RL1, Hope JC2, Stevens MP2.  Infect Immun. 2018 Jan 16. pii: IAI.00683-17. doi: 10.1128/IAI.00683-17. [Epub ahead of print]

New work from Andrew Rambaut's group in the School of Biological Sciences has found long-term MERS-CoV evolution occurs exclusively in camels and suggests MERS-CoV is unlikely to become endemic in humans.

MERS-CoV spillover at the camel-human interface.  Dudas G1, Carvalho LM2, Rambaut A2,3, Bedford T1.  Elife. 2018 Jan 16;7. pii: e31257. doi: 10.7554/eLife.31257.

New review on seasonality of RSV infection from Dr Harish Nair in the Usher Institute

Respiratory Syncytial Virus Seasonality: A Global Overview.  Obando-Pacheco P1,2, Justicia-Grande AJ1,2, Rivero-Calle I1,2, Rodríguez-Tenreiro C1,2, Sly P3, Ramilo O4,5,6, Mejías A4,5,6, Baraldi E4,7, Papadopoulos NG4,8,9, Nair H4,10, Nunes MC4,11,12, Kragten-Tabatabaie L4,13, Heikkinen T4,14, Greenough A4,15, Stein RT4,16, Manzoni P4,17, Bont L4,18, Martinón-Torres F1,2,4.  J Infect Dis. 2018 Jan 30. doi: 10.1093/infdis/jiy056. [Epub ahead of print]

Work from the School of Biological Sciences researchers identifies key adaptive sequence changes in human malaria parasite Plasmodium falciparium that led to human versus ape host specificity

Adaptive Evolution of RH5 in Ape Plasmodium species of the Laverania Subgenus.  Plenderleith LJ1,2, Liu W3, MacLean OA1,2, Li Y3, Loy DE3,4, Sundararaman SA3,4, Bibollet-Ruche F3, Learn GH3, Hahn BH3,4, Sharp PM5,2.  MBio. 2018 Jan 23;9(1). pii: e02237-17. doi: 10.1128/mBio.02237-17.

New work involving researchers from the School of Biological Sciences on the persistence of Ebola virus in survivors of infection has Implications for treatment options and public health recommendations

Active Ebola Virus Replication and Heterogeneous Evolutionary Rates in EVD Survivors.  Whitmer SLM1, Ladner JT2, Wiley MR2, Patel K3, Dudas G4, Rambaut A5, Sahr F6, Prieto K2, Shepard SS7, Carmody E8, Knust B3, Naidoo D9, Deen G10, Formenty P9, Nichol ST3, Palacios G2, Ströher U11; Ebola Virus Persistence Study Group.  Cell Rep. 2018 Jan 30;22(5):1159-1168. doi: 10.1016/j.celrep.2018.01.008.

New phylogenetic analyses by researchers from SBS and CIIE reveal multiple cross-species transmissions of viruses, both within and among mammalian species

Genetic diversity and cross-species transmission of kobuviruses in Vietnam.  Lu L1, Van Dung N2, Ivens A1, Bogaardt C1, O'Toole A1, Bryant JE2,3, Carrique-Mas J2,4, Van Cuong N4, Anh PH4, Rabaa MA2,4, Tue NT4, Thwaites GE2,4, Baker S2,4,5, Simmonds P2, Woolhouse ME1; VIZIONS Consortium.  Virus Evol. 2018 Feb 13;4(1):vey002. doi: 10.1093/ve/vey002. eCollection 2018 Jan.

December 2017

New paper describes rare occurrence of patient -patient hepatitis C transmission in a Scottish A&E department

Molecular and Epidemiological Evidence of Patient-to-Patient Hepatitis C virus Transmission in a Scottish Emergency Department.  Johannessen I, Danial J, Smith DB, Richards J, Imrie L, Rankin A, Willocks LJ, Evans C, Leen C, Gibson P, Simmonds P, Goldberg D, McCallum A, Roy K.  J Hosp Infect. 2017 Dec 11. pii: S0195-6701(17)30677-1. doi: 10.1016/j.jhin.2017.12.006. [Epub ahead of print]

New work from colleagues in the MRC Centre of Inflammation Research and Heriot Watt University has developed new in vitro systems that will allow better testing of immunological and stress responses to nanomaterials

Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials.  Johnston HJ, Verdon R, Gillies S, Brown DM, Fernandes TF, Henry TB, Rossi AG, Tran L, Tucker C, Tyler CR4, Stone V.  Crit Rev Toxicol. 2017 Dec 14:1-20. doi: 10.1080/10408444.2017.1404965. [Epub ahead of print]

New paper involving the Roslin Institute shows that diet has important effects on presence of AMR genes in the gut microbiome of beef cattle

The rumen microbiome as a reservoir of antimicrobial resistance and pathogenicity genes is directly affected by diet in beef cattle. Auffret M, Dewhurst RJ, Duthie CA, Rooke JA, John Wallace R , Freeman TC, Stewart R, Watson M, Roehe R.  Microbiome. 2017 Dec 11;5(1):159. doi: 10.1186/s40168-017-0378-z.

New study shows vitamin D3 in cattle can inhibit key immune cells - this may affect how animals respond to diseases such as tuberculosis or paratuberculosis

1,25-Dihydroxyvitamin D3 modulates the phenotype and function of Monocyte derived dendritic cells in cattle.  Corripio-Miyar Y, Mellanby RJ, Morrison K, McNeilly TN.  BMC Vet Res. 2017 Dec 13;13(1):390. doi: 10.1186/s12917-017-1309-8.

Work involving researchers from the School of Biological Sciences sheds light on how pyruvate kinase, a key metabolic enzyme in the Tuberculosis bacterium, has evolved to adapt to the environmental challenges encountered during infection        

Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.    Zhong W, Cui L, Goh BC, Cai Q, Ho P, Chionh YH, Yuan M, Sahili AE, Fothergill-Gilmore LA5, Walkinshaw MD, Lescar J, Dedon PC.    Nat Commun. 2017 Dec 7;8(1):1986. doi: 10.1038/s41467-017-02086-y.

New paper from researchers at the MRC Centre for Inflammation Research and the Edinburgh Cancer Centre describes a new signalling pathway involving IL33 that could be targetted to boost antitumour immunity in patients     

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks.    Serrels B, McGivern N, Canel M, Byron A, Johnson SC, McSorley HJ, Quinn N, Taggart D, Von Kreigsheim A, Anderton SM, Serrels A, Frame MC.    Sci Signal. 2017 Dec 5;10(508). pii: eaan8355. doi: 10.1126/scisignal.aan8355.

November 2017

 How do PrPSc Prions Spread between Host Species, and within Hosts?  Mabbott NA.  Pathogens. 2017 Nov 24;6(4). pii: E60. doi: 10.3390/pathogens6040060.

Work from the Roslin Institue uses WGS to simultaneously map the of fate of multiple Salmonella strains in a single animal - implications for testing efficacy of vaccines and treatments        

Quantifying the Survival of Multiple Salmonella enterica Serovars in vivo using Massively-parallel Whole Genome Sequencing to Predict Zoonotic Risk.    Vohra P, Bugarel M, Turner F, Loneragan GH, Hope JC, Hopkins J, Stevens MP.    Appl Environ Microbiol. 2017 Nov 27. pii: AEM.02262-17. doi: 10.1128/AEM.02262-17. [Epub ahead of print]

New paper from the Roslin Institute discusses the risk  and challenges posed by infectivity present during the subclinical phases of vCJD        

Public health risks from subclinical variant CJD.   Diack AB, Will RG, Manson JC.  PLoS Pathog. 2017 Nov 30;13(11):e1006642. doi: 10.1371/journal.ppat.1006642. eCollection 2017 Nov.  

People, Patches, and Parasites: The Case of Trypanosomiasis in Zimbabwe.    Scoones I, Dzingirai V, Anderson N, MacLeod E, Mangwanya L, Matawa F, Murwira A, Nyakupinda L, Shereni W, Welburn SC.    Hum Ecol Interdiscip J. 2017;45(5):643-654. doi: 10.1007/s10745-017-9929-y. Epub 2017 Sep 13.

Study from the School of Biological Sciences and the MRC Centre for Inflammation Research shows a helminth parasite has acquired a cytokine-like protein through convergent evolution, that is able to directly modulate the host immune response 

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.    Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ2, Woodcock HV10, Chambers RC10, Hinck AP4, McSorley HJ1,8, Maizels RM11.    Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6.

New study by researchers at Edinburgh vet school describes efficacy of anthelmintic treatments in Malaysian goat farms        

Assessment of gastrointestinal nematode infection, anthelmintic usage and husbandry practices on two small-scale goat farms in Malaysia.    Wong F, Sargison N.    Trop Anim Health Prod. 2017 Nov 15. doi: 10.1007/s11250-017-1472-8. [Epub ahead of print]

Work from Mark Bronsvoort and colleageus at the Roslin Institute reveals rapid evolution of African swine fever viruses in Kenya and Uganda during 2011-13         

Multi-locus sequence typing of African swine fever viruses from endemic regions of Kenya and Eastern Uganda (2011-2013) reveals rapid B602L central variable region evolution.    Onzere CK, Bastos AD, Okoth EA, Lichoti JK, Bochere EN, Owido MG, Ndambuki G, Bronsvoort M, Bishop RP.    Virus Genes. 2017 Nov 15. doi: 10.1007/s11262-017-1521-4. [Epub ahead of print]

New paper from the Moredun Institute adds to the growing evidence that miRNAs released from parasitic helminths may play an important role in host-parasite interactions        

Conservation of a microRNA cluster in parasitic nematodes and profiling of miRNAs in excretory-secretory products and microvesicles of Haemonchus contortus.    Gu HY, Marks ND, Winter AD, Weir W, Tzelos T, McNeilly TN, Britton C, Devaney E.    PLoS Negl Trop Dis. 2017 Nov 16;11(11):e0006056. doi: 10.1371/journal.pntd.0006056. [Epub ahead of print]

Work from the School of Biological Sciences suggests that engineering tumor-restricted T cells with mutations identified as risk factors for autoimmunity may improve anti-tumor adoptive cell therapy         

Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22.  Brownlie RJ, Garcia C, Ravasz M, Zehn D, Salmond RJ, Zamoyska R.  Nat Commun. 2017 Nov 7;8(1):1343. doi: 10.1038/s41467-017-01427-1.   

P-glycoproteins play a role in ivermectin resistance in cyathostomins.    Peachey LE, Pinchbeck GL, Matthews JB, Burden FA, Lespine A, von Samson-Himmelstjerna G, Krücken J, Hodgkinson JE2.    Int J Parasitol Drugs Drug Resist. 2017 Oct 25;7(3):388-398. doi: 10.1016/j.ijpddr.2017.10.006. [Epub ahead of print]

Review involving Prof Jürgen Schwarze at the the MRC Cnetre for Inflammation Research addresses uncertainties in the prevention and management of influenza in people with asthma       

Influenza burden, prevention and treatment in asthma - a scoping review by the EAACI Influenza in Asthma Task Force.    Schwarze J, Openshaw P, Jha A, Del Giacco SR, Firinu D, Tsilochristou O, Roberts G, Selby A, Akdis C, Agache I, Custovic A8, Heffler E9, Pinna G10, Khaitov M11, Nikonova A11, Papadopoulos N12, Akhlaq A13, Nurmatov U14, Renz H15, Sheikh A16, Skevaki C15.    Allergy. 2017 Nov 6. doi: 10.1111/all.13333. [Epub ahead of print]

New review including colleagues at the Moredun Resarch Institute disucssing key research priorities for GI nematode control in farmed ruminants and pigs        

Mind the gaps in research on the control of gastrointestinal nematodes of farmed ruminants and pigs.    Charlier J, Thamsborg SM, Bartley DJ, Skuce PJ, Kenyon F, Geurden T, Hoste H, Williams AR, Sotiraki S, Höglund J, Chartier C9, Geldhof P10, van Dijk J11, Rinaldi L12, Morgan ER13,14, von Samson-Himmelstjerna G15, Vercruysse J10, Claerebout E10.    Transbound Emerg Dis. 2017 Nov 10. doi: 10.1111/tbed.12707. [Epub ahead of print]

New work from David Gally and colleagues at the Roslin Institute on multi-drug resistance in E.coli from a veterinary clinical care setting     

Convergence of plasmid architectures drives emergence of multi-drug resistance in a clonally diverse Escherichia coli population from a veterinary clinical care setting.    Wagner S1, Lupolova N1, Gally DL1, Argyle SA2.    Vet Microbiol. 2017 Nov;211:6-14. doi: 10.1016/j.vetmic.2017.09.016. Epub 2017 Sep 22.Work from the Roslin Institute on virion assembly in human cytomegalovirus infection    

Cellular v-ATPase is required for virion assembly compartment formation in human cytomegalovirus infection.    Pavelin J1, McCormick D1, Chiweshe S1, Ramachandran S1, Lin YT1, Grey F2.    Open Biol. 2017 Nov;7(11). pii: 160298. doi: 10.1098/rsob.160298.

October 2017

Study identifies new routes for purification of manufactured red blood cells        

High-throughput assessment of mechanical properties of stem cell derived red blood cells, toward cellular downstream processing.    Guzniczak E1, Mohammad Zadeh M2, Dempsey F3, Jimenez M4, Bock H2, Whyte G2, Willoughby N2, Bridle H2.    Sci Rep. 2017 Oct 31;7(1):14457. doi: 10.1038/s41598-017-14958-w.

New study from the MRC Centre for Inflammation Research sheds light on pathogensis of multiple sclerosis        

TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells.    Ni Choileain S1, Hay J1, Thomas J2, Williams A3, Vermeren MM1, Benezech C4, Gomez-Salazar M1, Hugues OR5, Vermeren S1, Howie SEM1, Dransfield I1, Astier AL6,7.    Sci Signal. 2017 Oct 24;10(502). pii: eaah6163. doi: 10.1126/scisignal.aah6163.

New paper from the School of Biological Sciences dissects antigen processing during vaccination        

Dissecting antigen processing and presentation routes in dermal vaccination strategies.    Platteel ACM1, Henri S2, Zaiss DM3, Sijts AJAM4.  Vaccine. 2017 Oct 24. pii: S0264-410X(17)31452-4. doi: 10.1016/j.vaccine.2017.10.044. [Epub ahead of print]

Co-infection with worms protects against viral lung infections through the microbiota        

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota.  McFarlane AJ1, McSorley HJ1, Davidson DJ2, Fitch PM1, Errington C3, Mackenzie KJ2, Gollwitzer ES4, Johnston CJC5, MacDonald AS6, Edwards MR7, Harris NL8, Marsland BJ4, Maizels RM5, Schwarze J9.    J Allergy Clin Immunol. 2017 Oct;140(4):1068-1078.e6. doi: 10.1016/j.jaci.2017.01.016. Epub 2017 Feb 11.

Study involving Edinburgh researchers sheds light on development of COPD        

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.    Bewley MA, Preston JA, Mohasin M, Marriott HM, Budd RC, Swales J, Collini P1, Greaves DR, Craig RW, Brightling CE, Donnelly LE, Barnes PJ, Singh D, Shapiro SD, Whyte MKB, Dockrell DH    Am J Respir Crit Care Med. 2017 Oct 1;196(7):845-855. doi: 10.1164/rccm.201608-1714OC.

New paper from Edinburgh researchers examines the economic and social consequences of trypanosome infection in Zambia

Estimating the economic and social consequences for patients diagnosed with human African trypanosomiasis in Muchinga, Lusaka and Eastern Provinces of Zambia (2004-2014).    Mwiinde AM1, Simuunza M, Namangala B, Chama-Chiliba CM, Machila N, Anderson N, Shaw A, Welburn SC.  Infect Dis Poverty. 2017 Oct 10;6(1):150. doi: 10.1186/s40249-017-0363-6.

New study from Peter Ghazal analyses neonatal immune responses to cytomagalovurus infection         

Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses.    Dantoft W, Martínez-Vicente P, Jafali J, Pérez-Martínez L, Martin K, Kotzamanis K, Craigon M, Auer M, Young NT, Walsh P, Marchant A, Angulo A, Forster T, Ghazal P.    Front Immunol. 2017 Sep 25;8:1146. doi: 10.3389/fimmu.2017.01146. eCollection 2017.

Work from the School of Biological Sciences demonstrates need for EGFR expression for host resistance to helminth infection        

Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.    Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM.    Immunity. 2017 Oct 17;47(4):710-722.e6. doi: 10.1016/j.immuni.2017.09.013.

New paper from the Roslin Institute analyses how antibiotics are used in British sheep flocks   

Quantitative analysis of antibiotic usage in British sheep flocks.    Davies P, Remnant JG, Green MJ, Gascoigne E, Gibbon N, Hyde R, Porteous JR, Schubert K, Lovatt F, Corbishley A.    Vet Rec. 2017 Oct 19. pii: vetrec-2017-104501. doi: 10.1136/vr.104501. [Epub ahead of print]

Edinburgh Researchers have been looking in worms for novel therapies to treat #asthma therapies   

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.    Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM3, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP, Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA, Schwarze J, Ivens AC8 Maizels RM, McSorley HJ.    Immunity. 2017 Oct 17;47(4):739-751.e5. doi: 10.1016/j.immuni.2017.09.015.

New paper from the Moredun Research Institute on effects of Neospora infection in dairy cattle        

Occurrence of abortions induced by Neospora caninum in dairy cattle from Santa Catarina, southern Brazil.    Macedo CAB, Macedo MFSB, Miura AC, Taroda A, Cardim ST, Innes EA, Katzer F, Cantón GJ, Chianini F, Headley SA, Garcia JL.    Rev Bras Parasitol Vet. 2017 Jul-Sep;26(3):292-298. doi: 10.1590/S1984-29612017051.

New paper from the Proteus team on development of advanced  techniques for endomicroscopy        

Ballistic and snake photon imaging for locating optical endomicroscopy fibres.    Tanner MG, Choudhary TR Craven TH, Mills B, Bradley M, Henderson RK, Dhaliwal K, Thomson RR.    Biomed Opt Express. 2017 Aug 14;8(9):4077-4095. doi: 10.1364/BOE.8.004077. eCollection 2017 Sep 1.

Paper with EID Director Ross Fitzgerald discusses priorities for better control of bovine mastitis        

Knowledge gaps and research priorities in Staphylococcus aureus mastitis control.    Rainard P, Foucras G, Fitzgerald JR, Watts JL, Koop G, Middleton JR.    Transbound Emerg Dis. 2017 Oct 6. doi: 10.1111/tbed.12698. [Epub ahead of print]

New tools for studying immunological responses in livestock developed by Edinburgh researchers       

Enhancing the toolbox to study IL-17A in cattle and sheep.    Wattegedera SR, Corripio-Miyar Y, Pang Y, Frew D, McNeilly TN, Palarea-Albaladejo J, McInnes CJ, Hope JC, Glass EJ, Entrican G.    Vet Res. 2017 Apr 8;48(1):20. doi: 10.1186/s13567-017-0426-5.

September 2017

Researchers at the Moredin Research Institute help develop model to study anaerobic bacterial Infection    

A Novel 3D Skin Explant Model to Study Anaerobic Bacterial Infection.    Maboni G, Davenport R, Sessford K, Baiker K, Jensen TK, Blanchard AM, Wattegedera S, Entrican G, Tötemeyer S.    Front Cell Infect Microbiol. 2017 Sep 14;7:404. doi: 10.3389/fcimb.2017.00404. eCollection 2017.

Work from the Roslin Institute on how Eimeria infection in chickens affects their microbiome        

Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology.    Macdonald SE, Nolan MJ, Harman K, Boulton K, Hume DA, Tomley FM, Stabler RA, Blake DP.    PLoS One. 2017 Sep 21;12(9):e0184890. doi: 10.1371/journal.pone.0184890. eCollection 2017.

New study from the Moredun Research Institute on efficacy of vaccines against poultry red mite       

Field evaluation of poultry red mite (Dermanyssus gallinae) native and recombinant prototype vaccines.    Bartley K, Turnbull F, Wright HW, Huntley JF, Palarea-Albaladejo J, Nath M, Nisbet AJ.    Vet Parasitol. 2017 Sep 15;244:25-34. doi: 10.1016/j.vetpar.2017.06.020. Epub 2017 Jun 27.

Peter Ghazal explains why a systems pharmacology approach is needed for therapy development        

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.    Benson H, Watterson S, Sharman J, Mpamhanga C, Parton A, Southan C, Harmar A, Ghazal P.    Br J Pharmacol. 2017 Sep 14. doi: 10.1111/bph.14037. [Epub ahead of print]

Study from the Roslin Institute on immune responses in pigs infected with small ssDNA viruses        

Markedly different immune responses and virus kinetics in littermates infected with porcine circovirus type 2 or porcine parvovirus type 1.    Opriessnig T, Gerber PF, Matzinger SR, Meng XJ, Halbur PG.    Vet Immunol Immunopathol. 2017 Sep;191:51-59. doi: 10.1016/j.vetimm.2017.08.003. Epub 2017 Aug 9.

Report with Dr Kate Templeton and colleagues at Edinburgh University on a recent mumps outbreak in students        

An outbreak of mumps with genetic strain variation in a highly vaccinated student population in Scotland.    Willocks LJ, Guerendiain D, Austin HI, Morrison KE, Cameron RL, Templeton KE, DE Lima VRF, Ewing R, Donovan W, Pollock KGJ.    Epidemiol Infect. 2017 Sep 14:1-7. doi: 10.1017/S0950268817002102. [Epub ahead of print]

A report from colleagues in the Usher Institute for Population Health and Informatics on global RSV-associated mortality in children       

Global respiratory syncytial virus-associated mortality in young children (RSV GOLD): a retrospective case series.    Scheltema NM, Gentile A, Lucion F, Nokes DJ, Munywoki PK, Madhi SA, Groome MJ, Cohen C, et al. Lancet Glob Health. 2017 Oct;5(10):e984-e991. doi: 10.1016/S2214-109X(17)30344-3.

Study from The Roslin Institute confirms E. coli O157 infection is wideespread in UK cattle    

British Escherichia coli O157 in Cattle Study (BECS): to determine the prevalence of E. coli O157 in herds with cattle destined for the food chain.    Henry MK, Tongue SC, Evans J, Webster C, McKENDRICK IJ, Morgan M, Willett A, Reeves A, Humphry RW, Gally DL, Gunn GJ, Chase-Topping ME.    Epidemiol Infect. 2017 Sep 19:1-12. doi: 10.1017/S0950268817002151. [Epub ahead of print]