Find about recent news from across the Edinburgh Infectious Diseases network Welcome to the new Wellcome Trust PhD students October 2024: At the start of this month 13 new students began their studies on two Wellcome Trust PhD programmes addressing One Health Models Disease, and Hosts, Pathogens and Global Health. Professor Josephine Pemberton receives the British Ecological Society’s highest honour Professor Josephine Pemberton has been awarded honorary membership by the British Ecological Society, for her research on wild animal populations which has led to ground-breaking insights into the natural world. Professor Paul Sharp wins Royal Society’s Darwin Medal Professor Paul Sharp FRS, is recognised by the Royal Society with a prestigious medal, created in memory of Charles Darwin FRS, for his research on the evolutionary origins of HIV and malaria. Research Focus: From sleeping sickness in domestic dogs to infectious, neoplastic lung disease in sheep A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. AMR expert network secures funds to tackle resistance A University of Edinburgh co-directed research network has received a £650,000 UKRI award to engage with communities and policymakers across the UK to reduce the AMR burden. Data insights aid in managing livestock disease spread A new analysis offers a comprehensive view of cattle movements, providing valuable insights for veterinary decision-making. Research projects on rabies and sleeping sickness win 2024 Ker Memorial Prize The 2024 Ker Memorial Prize in Infectious Diseases has been jointly awarded to Dr Andy Gibson (Royal (Dick) School of Veterinary Studies) and Dr Guy Oldrieve (School of Biological Sciences). Research focus: from AMR resistance in seals to genetic mutations helping humans and animals survive against antibiotics A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. Mutation drives bacterial adaptation to immune response Researchers have uncovered a genetic mutation that helps common bacteria affecting humans and animals to survive against immune defences and antibiotics. Major new appointments in infection research for the School of Biological Sciences The Institute for Immunology and Infection Research in the School of Biological Sciences is delighted to welcome three new colleagues to join us in Edinburgh in 2024 Wellcome Trust PhD candidate publishes first book on outbreak prepardeness and response 'The Outbreak Atlas' written by Mackenize S. Moore, a student of the Hosts, Pathogens and Global Health PhD Programme, and Dr Rebecca Katz, Director of the Centre for Global Health, Science and Security at Georgetown University lifts the curtain on the rationale and interconnectedness of outbreak responses across different fields and at various levels. Past and present directors of Edinburgh Infectious Diseases named as RSE fellows Current co-director of Edinburgh Infectious Diseases Prof David Dockrell and former director Prof Ross Fitzgerald, have been named as fellows of the Royal Society of Edinburgh. Squirrelpox virus spreads north of central Scotland Scientists from the Royal (Dick) School of Veterinary Studies have confirmed the death of a red squirrel from squirrelpox virus in an area previously unaffected by the disease. Research focus: from abortions in livestock to immune traits in Scottish Blackface sheep A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. Newly announced Research and Innovation Strategy encompasses EID's themes The University of Edinburgh's Research and and Innovation Strategy 2030 highlights the importance of cross-college initiatives like Edinburgh Infectious Diseases as key platforms for delivering the new strategy. Building capacity to tackle antimicrobial resistance in Africa Reflections on the work of the Fleming Fund Fellowship schemes in Uganda, Malawi and Kenya, that are building expertise in AMR surveillance. Trust in NHS advice key to Covid vaccine uptake People’s trust in the NHS was linked to increased uptake of the Covid-19 vaccine during the pandemic, a study suggests. Virus ancestry could aid bid to predict next pandemic, study finds Virus family history could help scientists identify which strains have potential to become the so-called Disease X that causes the next global pandemic. West Nile virus study sheds light on mitigating outbreaks Mapping development of mosquito-borne virus offers clarity on managing risk of infections. Institute of Regeneration and Repair facility opened by Princess Royal Chancellor of the University of Edinburgh, Her Royal Highness The Princess Royal, has opened a flagship building designed to help researchers address some of the world’s most pressing health concerns. 2023 Winter lecture, World AMR Awareness Week and a trip to Brussels November was a very busy month for Edinburgh Infectious Diseases with three big events occuring in close proximity to one another: the annual Winter Lecture, World AMR Awareness Week and the UK Mission to the EU One Health Fair in Brussels. Research focus: from a digital one health framework to covid infections in cats A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. Kenyan Policy Fellows shine light on Silent Pandemic through powerful documentary November 2023: Kenyan Policy fellows, Evelyn Wesangula and Romona Ndanyi, collaborated on a documentary that explores the complexities of AMR in Kenya, aiming to captivate the attention of both policymakers and the general public. £3.3m award supports research into tackling bird flu Next phase of UK collaboration builds on discoveries around disease immunity, transmission and evolution. Summer school focuses on infectious disease research International initiative helps early career scientists develop their skills in studying infectious diseases. Research focus: from immune responses in fruit flies to chickens resistant to avian influenza A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. Gene-edited chickens take significant step in fight against bird flu Scientists have used gene editing techniques to identify and change parts of chicken DNA that could limit the spread of the bird flu virus in the animals. Taking malaria research to rural primary schools around Scotland Researchers from Professor Sarah Reece's lab in the School of Biological Sciences are engaging with teachers and pupils across Scotland to talk about mosquitos, malaria parasites and body clocks. Research focus: analysis of COVID-19 hospitalisations to infections associated with wildlife A collection of publication highlights from the Edinburgh Infectious Diseases network over the past month. Prof Amy Buck is honoured with the Max Planck-Humboldt Medal The Max Planck-Humboldt medal 2023 has been awarded to Amy Buck, Professor of RNA and Infection Biology, for her research into inter-species communication via RNA. The medal will be presented this November in Berlin. Research focus: from canine infections to assessing the impact of HPV Vaccine in Scotland A compilation of notable publication highlights from the Edinburgh Infectious Diseases network over the past month. Test could transform care for costly cattle disease Efforts to develop a field-side test for animal trypanosomiasis could transform management of the common, costly infection in smallholder farms. Pig gene is critical for African Swine Fever infection Lab study pinpoints immunity-linked gene in pigs that is required for African Swine Fever virus to replicate. TB vaccine protects calves in first weeks of life Inoculation within the first month of life is effective, offering greater scope for protecting calves against disease. Moredun awarded grant to develop new vaccines for bovine respiratory disease Moredun Research Institute (MRI), in collaboration with French animal health company Ceva Sante Animale (Ceva), have been awarded £900,000 (80% funded) to develop new vaccines that target the viruses and bacteria responsible for bovine respiratory disease (BRD). App offers fast method of tracing infectious diseases Pilot study shows a novel contact tracing app could help protect groups at risk of catching and spreading infectious diseases in the Global South. Parasites of viruses drive superbug evolution Newly discovered mechanism enables bacteria to rapidly evolve, and could inform phage therapy. Rapid infection test could curb antibiotic resistance Novel system speeds diagnosis of bacterial infections in dogs, enabling effective choice of treatment. Covid risk study pinpoints ethnic inequalities Scotland’s White Gypsy/Traveller ethnic minority group were at greater risk of Covid-19 hospitalisation or death than the majority of the population, research reveals. Malawi's Alumni Fleming Fund Fellows visit Edinburgh University of Edinburgh hosts Alumni Fleming Fund Fellows from Malawi, accompanied by Dr. Collins Mitambo, Head of Research at the Ministry of Health. Research focus: from eye infection to future pandemic preparedness Publication highlights from the Edinburgh Infectious Diseases network in the past month. £46.3 million funding boost to shine light on dark genome Scientists at the University of Edinburgh will receive £46.3 million from the Medical Research Council (MRC) to support ongoing activity at the MRC Human Genetics Unit. Genetic material linked to dairy calf development Molecular material associated with growth, fertility, and infection risk in dairy calves could serve as indicator of productivity in cows. Key gene blocks spillover of avian flu to humans Newly identified gene shown to prevent most strains of bird flu from causing infection in humans. Deer reveal nature’s secrets across half a century A 50-year study of red deer on a remote Scottish island is providing new insights into evolution in action and the impact of climate change in the natural world. Research focus: from chicken vaccines to the global response to AMR Explore the noteworthy publications from Edinburgh Infectious Diseases in the past month. 12th Annual Edinburgh Infectious Diseases Symposium Details about the programme, Ker Memorial Speaker and Prize Winner, and voting arrangements for the poster sessions for this year's Annual Symposium Unraveling cattle immunity: the role of epigenetic markers Unveiling cattle immune system diversity and disease resistance potential through DNA chemical markers Verity Hill awarded 2023 Ker Memorial Prize in Infectious Diseases We are delighted to announce that Dr Verity Hill, from Prof Andrew Rambaut's lab in the School of Biological Sciences, is the winner of this year's prize for her work on Ebola and SARS-CoV-2. Congratulations to the nominees for the Ker Memorial Prize 2023 The Ker Memorial Prize is awarded annually for the best PhD thesis in infectious diseases at the University of Edinburgh. Professor Lisa Boden appointed new Head of the Royal (Dick) School of Veterinary Studies A leading specialist in veterinary public health and population medicine has been appointed as the new Head of the Royal (Dick) School of Veterinary Studies. Research focus: From Influenza to plant pathogens and global health A compilation of notable publication highlights from the Edinburgh Infectious Diseases network over the past month. Method offers boost to safety profile of live vaccines Weakening virus by amending genetic code promises route to large-scale production of live vaccines. Successful symposium on AMR in Livestock Production in a One Health Context The OECD-CRP Symposium on AMR in Livestock Production in a One Health Context was held in Edinburgh on 22-24 May 2023. Research focus: April 2023 - from Avian flu to equitable global health A digest of the publication highlights from across the Edinburgh Infectious Diseases network over the past month. Hands on with infection biology at the Edinburgh Science Festival The Edinburgh Science Festival ran a vibrant programme of activities for all ages at the National Museum of Scotland during the Easter break in April 2023. Congratulations to the new Chancellor's Fellows in the College of Science and Engineering A group of outstanding early career researchers have been awarded one of the University of Edinburgh’s most prestigious fellowships. Fellowships recognise leading research talent at the Roslin Institute Prestigious awards from University and BBSRC nurture outstanding scientists and pioneering projects. Konrad Adenauer Foundation Scholars visit Edinburgh The group of 24 students were in Edinburgh as part of a study tour to learn about "Science: Study, Research and Life. A comparison of the systems in Germany and Great Britain ". Long-term approach on bird flu is best, study finds Lasting conservation measures targeted at most vulnerable species are recommended in a report for the Scottish Government. Research Focus: From fruit fly survival to imaging immune cells We explore publication highlights from across Edinburgh Infectious Diseases, March 2023. Study provides insights into child hepatitis outbreak A common virus, alongside an underlying genetic predisposition, is likely to have played a key role in the recent worldwide outbreak of acute hepatitis in children. Scottish communities to use Minecraft to learn about disease spread A video-game based model of infectious disease spread will form the basis of a pilot public engagement project that aims to engage Scottish communities with public health research data. Global health research needs gravity shift to deliver impact A successful Africa-led global health research programme, contributing to World Health Organisation (WHO) policy development, has shared the key to its success and is calling for a shift in the centre of gravity of health research, designed to benefit developing countries. Covid-19 vaccine not linked with period disruption, study finds Covid-19 vaccination does not cause concerning changes to periods, research has found. Fossil site is ‘Rosetta Stone’ for understanding early life Leading edge technology has uncovered secrets about a world-renowned fossil hoard that could offer vital clues about early life on earth. University commits fund for African partnerships A multi-year commitment to explore innovative educational opportunities for African students and build research partnerships across the African continent has been announced by the University of Edinburgh. Whether born naturally or via cesarean section, babies receive essential microbes from their mothers Do cesarean-born babies miss out on essential microbes? New evidence suggests that the answer may be “no.” Covid rule fines peaked in latter stages of lockdown, study finds Most fines for Covid rule breaches were issued when England was in its third national lockdown and Wales was in its second, research shows. Multi-species study aids understanding of bird flu Response to infection in birds from chickens to crows points to biological factors linked to disease resistance. Research focus: from apes to organoids We explore publication highlights from across Edinburgh Infectious Diseases, Feb 2023. Common cold may have helped curb Africa’s Covid-19 death toll The higher prevalence of common cold viruses in Africa may have helped the continent experience relatively lower death rates from Covid-19, a study of people in Zimbabwe suggests. Covid-19: Targeting sugar-binding proteins and immunity in cancer patients Recent Covid-19 clinical trial results from Edinburgh Infectious Diseases Covid-19 vaccine scientists win prestigious prize Two scientists who made important contributions to the development of Covid-19 vaccines have received a prestigious award from the University of Edinburgh. Highlights from 2022 Featuring reflections of some of the stories that took place across Edinburgh Infectious Diseases – Covid-19 risks and recovery plans, liver regrowth by leprosy bacteria, the evolution of antibiotic resistance and more. Intensive farming and trade drove spread of livestock infection Evolutionary study of bacteria that cause a common infection of cattle reveals their origin and spread via ocean trade links, shedding light on modern-day disease. Scotland’s Covid-19 sewage data could reveal new health insights Data from Scotland’s Covid-19 Wastewater Programme could offer future insights into the pandemic, its long-term health impacts and help tackle other viruses. Baby’s jab responses linked to birth delivery method, study finds The method by which a baby was delivered is associated with how its immune system will respond to two key childhood vaccines, research suggests. Ancient disease has potential to regenerate livers Leprosy is one of the world’s oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ. World Antibiotic Awareness Week 2022 - Edinburgh AMR Showcase To mark World Antibiotic Awareness Week 2022, on 21 November 2022 the Edinburgh AMR Forum is hosting the AMR showcase. Genetic analysis key to understanding Legionella risk, study finds Routine sampling of water supplies and genomic sequencing – determination of the entire genetic makeup - of Legionella bacteria could play a key role in identifying the source of Legionnaires’ disease outbreaks, research suggests. Fighting a pandemic using Digital Contact Tracing in Uganda’s haulage industry A new study fully documents the development of a Digital Contact Tracing tool for use on the African continent. Post-pandemic diet shifts could avert millions of premature deaths Covid-19 recovery plans should focus on healthier diets as much as economic growth to prevent huge numbers of avoidable deaths, research suggests. Recordings now available from 11th Annual Symposium Together Again, the 11th Annual Symposium from Edinburgh Infectious Diseases, was held on Thursday 23 June at the Roslin Institute. Keith Matthews receives 2023 Alice and C. C. Wang award in Molecular Parasitology Many congratulations to Prof Keith Matthews, chair of Parasite Biology in the School of Biological Science, who has received the award for seminal contributions to the field. 2022 Ker Memorial Prize awarded to Dr Mabel Tettey The annual prize for the most outstanding PhD thesis in Infectious Diseases has been awarded to Mabel Tettey in the School of Biological Sciences. Vaccine campaign to free Indian state from rabies Data-driven, One Health approach puts Goa on target to eliminate disease and save lives. Pandemic Science Hub to develop better drugs to fight lung disease A new multi-million pound research programme to develop treatments for lung infections such as Covid-19 and future pandemics has been announced at the University of Edinburgh with support from a significant donation by Baillie Gifford. National assessment highlights research excellence in agriculture, food and veterinary sciences UK Research Excellence Framework results affirm outstanding research environment and impact on society. School of Biological Sciences Ranked in UK Top 5 for Research Quality The School of Biological Sciences is ranked fifth in the UK, and top ranked in Scotland, for the quality and breadth of its research, known as research power, by Times Higher Education. Research rankings confirm Edinburgh as world leader Edinburgh’s position as one of the UK’s leading research universities has been reaffirmed by the results of the 2021 Research Excellence Framework (REF). Study sheds light on bacterial sharing between humans and animals A recent paper demonstrates how infectious diseases and antimicrobial resistance can be shared between humans and animals in an urban environment. Century-old malaria parasite puzzle solved as ape origin traced Researchers in Edinburgh have solved a 100-year-old mystery about the evolutionary links between malaria parasites that infect humans and chimpanzees. Fleming Fund AMR fellows visit Edinburgh The Fleming Fund supports training and capacity building for surveillance of antimicrobial resistance in low and middle income countries. Together Again - 2022 Edinburgh Infectious Diseases Symposium The 11th Annual Edinburgh Infectious Diseases Symposium will be held on Thursday 23 June 2022 - please save-the-date. Covid-19 mixed with flu increases risk of severe illness and death Adults in hospital who have Covid-19 and the flu at the same time are at much greater risk of severe disease and death compared with patients who have Covid-19 alone or with other viruses, research shows. Tackling Toxoplasmosis: A new animated film about the world’s most successful parasite The Moredun Research Institute Moredun has released a short animation to help inform and educate people about Toxoplasma gondii. Antibiotics after birth affects gut microbes of babies, study finds Treating babies with antibiotics in the first week of life is linked with a decrease in healthy bacteria necessary to digest milk and an increase in antimicrobial resistance, research suggests. Edinburgh work with Fleming Fund fellowships highlighted by ICARS The University of Edinburgh's work with the Fleming Fund fellowship Scheme has been highlighted by the conference organised by the International Centre for AMR Solutions (ICARS). First virus infection linked with infections later in life, study finds Asymptomatic viral infections in the first days and weeks of a baby’s life are associated with an increased risk of respiratory infections later in life, research suggests. Antibiotic resistance predates modern medicine Bacteria with antibiotic resistance infected wildlife centuries ago, DNA family tree shows. Bacterial gene has key role in Legionnaires’ disease A large-scale study of bacterial DNA samples had uncovered the significance of a gene in causing human infections. Black children overlooked in scar tissue disorder tests, study says An immune disease that can damage vital organs – and is supposedly rare in young people – is more common than previously thought among Black children, a study from the School of Biological Sciences suggests. Genetic contact tracing could help curb early TB outbreaks The novel use of genetic contact tracing to identify the source of a bovine tuberculosis outbreak could signal a new approach in managing the disease, a study suggests. Edinburgh Infectious Diseases Winter Lecture 2021 – Sir Jeremy Farrar This year we are delighted to have Sir Jeremy Farrar, Director of the Wellcome Trust, giving our annual public Winter Lecture on Tuesday 16 November. Wellcome Trust 4-year PhD programmes now recruiting for 2022 Edinburgh Infectious Diseases is delighted to announce that we are now accepting applications for the 2022 cohorts of students on two Wellcome Trust funded 4-year PhD programmes. Vaccines offer strong protection against death from Delta, study says Vaccination is over 90 per cent effective at preventing deaths from the Delta variant of Covid-19, according to the first country-level data on mortality. Remote monitoring provides early help for Covid-19 patients Patients at risk of developing severe Covid-19 symptoms have been successfully treated at an early stage thanks to the use of a remote monitoring service. New study challenges understanding of pandemic preparedness and resilience in Africa Countries in Africa assessed as being least vulnerable to an epidemic were the worst affected by Covid-19, new research suggests. Call for speakers: Edinburgh Infectious Diseases Early Career Researcher Symposium We are delighted to open the call for speakers at the first Edinburgh Infectious Diseases Early Career Researcher Symposium. New research into novel vaccines against ovine enzootic abortion at Moredun A new vaccine being developed against ovine enzootic abortion by scientists at the Moredun Research Institute has shown very promising results in laboratory trials. On World Mosquito Day 2021 highlighting researchers at the University of Edinburgh studying malaria Here we highlight some of the groundbreaking researchers based in the School of Biological Sciences at the University of Edinburgh who are tackling malaria. Urgent action is needed to tackle impact of early childhood schistosomiasis on education A new study reveals that the negative impacts of schistosome infection on early child development and educational attainment can be reversed within 6 months after treatment with the drug praziquantel. Genetic variations linked to severe Covid-19 risk identified Edinburgh researchers are part of an international consortium who have discovered 13 DNA sequences that are associated with people developing the most severe form of Covid-19. Listen again: Keeping Connected - 10th Annual Symposium We were delighted to host our virtual Annual Symposium on Wednesday 24 June 2021. Fast, precise and unintrusive Covid tests trialled at University A potentially more accurate, less invasive and cheaper method of screening for Covid-19 is being piloted at the University of Edinburgh. Delta variant increases hospitalisation but vaccine continues to protect The Delta variant of Covid-19 is associated with approximately double the risk of hospitalisation compared with the Alpha variant, according to a new nationwide study. Dr Derick Osakunor is winner of 2021 Ker Memorial Prize Derick Osakunor was awarded the prize for his work with Prof Francisca Mutapi on the treatment and control of Schistosomiasis in preschool aged children. Covid vaccine linked to low platelet count, nationwide study suggests A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests. Professor Julie Fitzpatrick OBE appointed Chief Scientific Advisor for Scotland Professor Fitzpatrick will take up the new advisory role with the Scottish Government on 14 June 2021. New Covid-19 dashboard launched to track spread across Scotland The Tracking and Modelling for Scotland dashboard provides interactive detailed weekly maps to track the spread of COVID-19 across the region, to help inform control strategies. Light-sensitive drug acts as Trojan horse to kill drug-resistant bacteria A light-activated drug that can enter and kill bacterial and cancer cells without harming nearby healthy cells has been tested successfully. 10th Annual Edinburgh Infectious Diseases Symposium - Keeping Connected We are delighted that we will be hosting our annual symposium on Wednesday 24 June 2021. Registration is now open! Covid-19 early warning system could avert future lockdowns Scientists are developing a coronavirus early warning system that could prevent future lockdowns by combining data on vaccine uptake with wastewater testing. Successful workshop on Disease Transmission Edinburgh Infectious Diseaes hosted a workshop on 29 April 2021 exploring key topics in transmission biology. Loeske Kruuk awarded ERC Advanced Grant Professor Loeske Kruuk, who will be joining the School of Biological Sciences later in 2021, has been awarded a European Research Council (ERC) Advanced Grant, to study evolution in wild animal populations. Sunlight linked with lower Covid-19 deaths, study suggests Increased exposure to the sun’s rays – specifically UVA - could act as a simple public health intervention if further research establishes it causes a reduction in mortality rates, experts say. €1M research project to focus on a progressive brain disease in deer A team led by researchers at the Roslin Institute will investigate the spread of Chronic Wasting Disease (CWD), a condition similar to BSE in cattle, in European deer. Francisca Mutapi selected as a TED2021 Fellow Global Health Professor to join the newest class of 20 global visionaries, sharing their big ideas throughout the events planned for 2021. Mysteries of malaria infections deepen after human trial study Scientists have discovered that tracking malaria as it develops in humans is a powerful way to detect how the malaria parasite causes a range of infection outcomes in its host. Edinburgh Disease Transmission workshop - registration now OPEN!! You are most welcome to join this online Edinburgh Infectious Diseases workshop on Thursday 29 April. Please register on Eventbrite. Malaria immunity insight could lead to new vaccine development Key insights on how malaria immunity develops after repeated infections could lead to new vaccine strategies and change the approach to tackling other infectious diseases, a study has found. Covid-19 vaccine roll-out working, first national study suggests Vaccination has been linked to a substantial reduction in the risk of Covid-19 admissions to Scotland’s hospitals, landmark research suggests. Altruism in bacteria - Gut microbes help family first The discovery that in real-world conditions bacteria, similar to animals, cooperate and selflessly act for the greater good of the group, could help scientists to predict how helpful and harmful strains behave. Loeske Kruuk awarded Royal Society Research Professorship Professor Loeske Kruuk will return to the School of Biological Sciences after being awarded a Royal Society Research Professorship, the Royal Society’s premier research award. Sara Macias awarded Wellcome Trust Senior Fellowship for work on interferon signalling Sara will receive £1.8M over the next five year to work on the project which seeks to understand the contribution of the miRNA-interferon interaction to human disease. £2.5M Wellcome Trust Investigator Award for Keith Matthews Prof Keith Matthews, member of Edinburgh Infectious Diseases in the School of Biological Sciences, will receive £2.5M over the next 5 years to support research into the African trypanosomes that cause sleeping sickness in humans and animals. Smart vaccine scheme quick to curb rabies threat in African cities More people could be protected from life-threatening rabies thanks to an agile approach to dog vaccination using smart phone technology to spot areas of low vaccination coverage in real time. Genes could be key to new Covid-19 treatments, study finds Potential treatments for Covid-19 have been identified after the discovery of five genes associated with the most severe form of the disease. ERC Grant Success - EID researchers awarded €4M in European funding Projects led by Amy Buck and Steven Spoel have been awarded funding by the European Research Council (ERC) in its latest Consolidator Grant competition for mid-career researchers. A look-back on 2019-20 in Edinburgh Infectious Diseases As this incredible year draws to a close, we would like to share with you some of the highlights for Edinburgh Infectious Diseases over the past 18 months. Belated Annual Symposium showcases work from across Edinburgh Infectious Diseases All the talks from the 9th Annual Edinburgh Infectious Diseases Symposium are now available to watch again. Public lecture: 9 Months of Discovery - How we found out why people die from Covid-19 2020 Edinburgh Infectious Diseases Winter Lecture: We are delighted to invite you to our Annual Winter Lecture, which this year will be given by Dr Kenneth Baillie on Wednesday 25 November at 5.30 pm. Open to a world of possibilities - One Health in Edinburgh On the eve of the 2020 World One Health Congress, the University of Edinburgh has launched an online showcase of our One Health approach to improving livelihoods around the world. Covid-19 drug trial raises prospect of home-based treatment A drug first developed more than 30 years ago is to have its effectiveness at reducing the progression of Covid-19 trialed in people who are self-isolating after testing positive for the disease. ‘Social distancing’ in sheep could cure flock of maedi-visna A collaboration between scientists in Scotland and The Netherlands has found that a lack of ‘social distancing’ between sheep is almost exclusively responsible for the spread of the virus that causes the chronic viral disease maedi-visna. Wellcome Trust 4-year PhD programmes now recruiting for 2021 Edinburgh Infectious Diseases is delighted to announce that we are now accepting applications for the 2021 cohorts of students on two Wellcome Trust funded 4-year PhD programmes. Registration now open!! Edinburgh Infectious Diseases Symposium - the virtual edition We are delighted to announce that participants can now register for the 9th Annual Edinburgh Infectious Diseases Symposium on 10 and 11 November 2020. High surface tension in red blood cells can prevent invasion by malaria parasite The secret of how the Dantu genetic blood variant helps to protect against malaria has been revealed for the first time by scientists at the University of Edinburgh, in collaboration with colleagues at the Wellcome Sanger Institute, the University of Cambridge and the KEMRI-Wellcome Trust Research Programme, Kenya. Novel study of poultry red mites awarded key funding A grant worth almost half a million pounds has been awarded to the Moredun Research Institute to develop a novel way of studying poultry red mites which greatly reduces the number of hens required. Caffeine shot delivers wakeup call on antifungal drug resistance The management of fungal infections in plants and humans could be transformed by a breakthrough in understanding how fungi develop resistance to drugs. Discovery of four Covid-19 risk groups helps guide treatment People who are admitted to hospital with Covid-19 can be divided into four distinct groups, according to data from the world’s largest study of patients with the disease. Covid-19 less deadly and causes milder symptoms in children Children and teenagers are less likely than adults to develop severe Covid-19 or die from the disease, according to the world’s largest study of hospital patients with Covid-19. Genetic insight holds promise of Covid-19 vaccine Detailed knowledge of the genetic code of the novel coronavirus could support efforts to develop a vaccine. Breakthrough vaccine vehicle for sheep and goats using trypanosomes Roslin Technologies, the UK’s specialist AgTech venture builder, is developing a unique vehicle to deliver vaccines to sheep and goats, using technology generated from a harmless single cell parasite found on a remote island in the North Atlantic. Scottish experts join global search for Covid-19 treatment Leading scientists from Universities of Edinburgh and Dundee have joined a €77.7 million initiative to find a treatment for Covid-19 and are optimistic progress can be made. Masks can block 99.9% of Covid-linked droplets, study shows People who wear a face mask significantly lower the risk of spreading Covid-19 to others through speaking and coughing, suggests research from the University of Edinburgh. Sustainable nylon production made possible by bacteria discovery Nylon manufacture could be revolutionised by the discovery that bacteria can make a key chemical involved in the process, without emitting harmful greenhouse gases. Experts call for closer wildlife monitoring to prevent future pandemics Global wildlife experts are calling for improvements to how pathogens are tested and tracked in wildlife, to reduce the risk of future pandemics. Scottish vet labs at the Moredun Institute to support NHS with Covid-19 testing Moredun Research Institute and Scotland’s Rural College (SRUC) are working together to support the NHS by providing extra capacity for vital testing of samples within their laboratory facilities at Pentlands Science Park in Midlothian. Stroke found to be Covid-19’s most common neurological complication Key research involving the University of Edinburgh, into Covid-19’s impact on the nervous system, shows stroke is the most commonly reported neurological complication affecting patients hospitalised by the virus. Edinburgh researchers to trial salt water solution to treat Covid-19 A simple salt water solution may help to reduce the early symptoms and progression of Covid-19, research suggests. New insights on Covid-19 at Edinburgh Coronavirus workshop The second Edinburgh Coronavirus workshop – Covid-19: three-months on – was held on 23 June 2020, to discuss work that is contributing to our understanding and response to the Covid-19 pandemic. Clocking in with malaria parasites Discovery of why timing matters to malaria parasites reveals a vulnerability that could be exploited for future treatment strategies. Second Edinburgh Coronavirus workshop on 23 June 2020 On Tuesday 23 June 2020 Edinburgh Infectious Diseases will host a second workshop on the current research and clinical activities in Edinburgh that are addressing the SARS-CoV-2/Covid-19 pandemic. Fight against common flu aided by gene discovery New treatments for flu could emerge from find of human genes targeted by flu viruses. Young Scots to be asked how Covid-19 is changing teen life Young people aged from 12 to 17 years old in Scotland are being asked to share their views and experiences of how the Covid-19 pandemic is affecting their lives. Most Scots trust Holyrood to halt new wave of Covid-19, poll finds A majority of people living in Scotland are confident the Scottish Government is capable of stopping a further outbreak of Covid-19, a survey suggests. University facility to provide essential proteins for coronavirus research The Edinburgh Protein Production Facility (EPPF) has joined a national consortium to provide medically important proteins that will aid coronavirus research. New study predicts global patterns of viral sharing among mammals New work by University of Edinburgh PhD student and the EcoHealth Alliance has provided the first broadly applicable model to estimate patterns of viral sharing globally – for all mammal species and all known viruses. Two-tier approach could start UK’s move out of lockdown Easing the UK’s Covid-19 lockdown could begin by strengthening protection for the most vulnerable while relaxing restrictions for everyone else, experts suggest. University project makes Covid-19 information accessible in different languages Members of Edinburgh Infectious Diseases have made translations of the presentations at the Edinburgh Coronavirus Workshop available in over twenty languages. Obesity hampers Covid-19 recovery prospects, study finds Reduced lung function and inflamed tissue under the skin and around internal organs could be linked to the increased risk, researchers say. Both factors can trigger a life-threatening over-reaction of the body’s immune response that causes harm to patients, the study suggests. Professor Keith Matthews elected Fellow of the Royal Society Keith Matthews, Professor of Parasite Biology in the Institute of Immunology and Infection Research at the University of Edinburgh, has been elected a Fellow of the Royal Society in recognition of his outstanding contribution to science. Laser-cut face guards to shield Covid-19 key workers Innovative face shields for key workers fighting Covid-19 can be made more quickly than other guards thanks to laser-cutting technology. University to support NHS by testing Covid-19 samples Scientists, laboratory space and equipment from the University of Edinburgh are being used to support NHS Lothian’s testing efforts to combat the Covid-19 pandemic. Survey to gauge Covid-19’s impact on our everyday lives A survey has been launched to capture how Covid-19 is affecting the mood of the nation. Covid-19 Perspectives from the College of Arts, Humanities and Social Science Academics from CAHSS are contributing informed opinion and comment about the Covid-19 pandemic on a new blogsite. Army of scientists re-deployed in search for Covid-19 treatments Up to 150 researchers at the University of Edinburgh’s Centre for Inflammation Research are being re-deployed to work on a project that aims to test existing and experimental drugs to find a treatment for Covid-19. PhD students rise to the challenge of Covid-19 Students from the Wellcome Trust PhD programme in Hosts, Pathogens and Global Health at the University of Edinburgh are taking on projects to help answer key questions in the Covid-19 pandemic. Critical courses made free to support NHS and global fightback against Covid-19 The University of Edinburgh has made a number of its courses available online for free in a bid to support frontline NHS staff in the fight against Covid-19. Edinburgh researchers to participate in EMBL Twinning Project on RNA biology David Tollervey, from the Wellcome Centre for Cell Biology and Sara Macias from the Institute of Immunology and Infection Research will take part in a twinning project with the Central European Institute of Technology and other partners, to share research expertise on RNA biology. Experts appointed to Covid-19 advisory group Four Edinburgh researchers have joined a group providing expert advice to the Scottish Government on its response to Covid-19. University fast-tracks innovation to battle COVID-19 Edinburgh researchers are joining forces with commercial companies to quickly develop new technologies to help tackle the Covid-19 pandemic. Edinburgh scientists to map COVID-19 spread Scientists from the University of Edinburgh and NHS Lothian have joined a UK consortium analysing the genetic code of Covid-19. Successful Edinburgh Coronavirus workshop On Wednesday 25 March Edinburgh Infectious Diseases hosted a workshop on the current research and clinical activities in Edinburgh that are addressing the SARS-CoV-2/COVID-19 pandemic. Experts play key role in bid to curb Covid-19 Researchers from across the University are rallying to support global efforts to combat the coronavirus outbreak. New funding to help understand how Covid-19 affects the most vulnerable The University of Edinburgh has received nearly £5 million to tackle the coronavirus pandemic from the government’s rapid response call. UK launches £20m whole genome sequence alliance to map spread of coronavirus A team of academics at the University of Edinburgh and NHS Lothian are part of national consortium that will look for breakthroughs that help the UK respond to this and future pandemics, and save lives. Facility to boost research into animal and human health Large Animal Research and Imaging Facility builds on animal science expertise at Easter Bush campus. Research gets a huge boost towards a new generation louping ill vaccine An exciting partnership has been launched between Moredun and the Game and Wildlife Conservation Trust (GWCT) to tackle the problem of louping ill. Congratulations to our new Fellows of the Royal Society of Edinburgh Huge congratulations to three members of Edinburgh Infectious Diseases who have been elected as Fellows of the Royal Society of Edinburgh! Using sewage for surveillance of antimicrobial resistance In a new article published in Science magazine, Prof Mark Woolhouse discusses how a global system for the surveillance of antimicrobial resistance would exploit sewage Infection with male-killing bugs hold key to African monarch butterflies’ curious colour changes It is a spectacular butterfly breed with an intriguing back story … now scientists have revealed how male-killing bacteria are helping to create a dazzling hybrid of the African monarch. Genetic resistance to lethal virus found in key farmed fish species Resistance to a deadly disease that is affecting the second most farmed fish in the world has been found to be mainly due to differences in genes between families of the same fish. Immune cell insights could aid flu vaccine design Understanding the role played by a key immune cell could inform the development of vaccines. New method aids study of poultry infections A method of sampling tissue could aid research into therapies for chicken lung diseases. Antibiotic resistance surprisingly stable in pigs Antimicrobial resistance gene counts did not change in response to antibiotic treatment. Genetic clues of TB spread between cows and badgers revealed Tuberculosis in cattle and badgers passes between members of the same species at least twice as often than between cow and badger, a study has found. New exhibition features research at Edinburgh University tackling deadly parasitic diseases A new exhibition highlighting Scottish research tackling parasitic diseases has opened at the National Museum of Scotland, and runs until 19 April 2020. African experts join forces to curb threat of tropical diseases Five African scientists are to study at the University of Edinburgh as part of a scheme to tackle infectious diseases. Potential harm of newly discovered viruses predicted by new study from University of Edinburgh The threat to global human health posed by newly emerging viruses such as Ebola, SARS and the Zika virus can be predicted, a study has found. Bacteria overcome hurdles to jump between species The remarkable ability of some bacteria to transfer from one species to another has been highlighted by a novel study method. New PhD programme in Integrated One Health Solutions Edinburgh Infectious Diseases is pleased to announce a strategic partnership between the Universities of Leiden and Edinburgh to offer six PhD studentships fully funded for four years focused on Integrated One Health Solutions. Advances in understanding infectious lung cancer in sheep may lead to new diagnostic tests A new study recently published in Journal of Virology has identified genetic changes occurring during the growth of lung cancer in sheep that improve understanding of how the disease develops. Climate lessons could aid antibiotics challenge Rising antimicrobial resistance, fuelled by overuse of treatments, could be curbed with a framework inspired by climate change targets. Wellcome Trust 4-year PhD programmes now recruiting Edinburgh Infectious Diseases is delighted to announce that recruitment has now opened for two Wellcome Trust funded 4-year PhD programmes at the University of Edinburgh. New study shows E. coli toxin in cattle is responsible for life-threatening bacterial disease in humans A new study shows that a specific toxin produced by naturally-occurring E. coli bacteria helps these bacteria colonise the intestinal tract of cattle, increases transmission of the bacteria to other animals in the herd, and promotes disease in humans. Wild animals’ immune systems decline with age, sheep study finds It is well established that weakened immune systems in old age affect people’s health and fitness, but a study suggests that it is also an issue for wild animals. Innovative science PhD programmes announced by the Wellcome Trust Edinburgh Infectious Diseases is delighted to announce that it has been awarded two prestigious 4-year PhD programmes by the Wellcome Trust. Edinburgh data centre to boost respiratory research and innovation A new data research centre, coordinated from Edinburgh, will help to improve the lives of people living with respiratory conditions. Chief Technology Officer and Innovation & Engagement Manager join Roslin Technologies In Summer 2019 The Chief Technology Officer, Prof Jacqui Matthews and the Innovation & Engagement manager, Dr. Karen Fairlie-Clarke joined the Roslin Technologies team. Uganda Fleming Fellowships in AMR surveillance at the University of Edinburgh The University of Edinburgh is hosting six fellows from Uganda to help build capacity in the surveillance of antimicrobial resistance and antibiotic use. Tell us what you think - we're all ears! To help us improve how we support research and training in infectious diseases in Edinburgh, we're seeking your feedback. A great showcase of infectious disease research in Edinburgh The eighth annual Edinburgh Infectious Diseases symposium from was held in June 2019, and once again was a vibrant showcase of the enormous variety of research being done across our network. Gene-edited chicken cells resist bird flu virus in the lab Scientists have used gene-editing techniques to stop the bird flu virus from spreading in chicken cells grown in the lab. Immune discovery may boost cancer therapies Cancer therapies that use immune cells to trigger the body to attack tumours could be improved by a molecule that boosts their function. 2019 Ker Memorial Prize awarded for work on the immune system in Drosophila Edinburgh Infectious Diseases is delighted to announce that the 2019 Ker Memorial Prize has been awarded to Dr Billy Palmer from the School of Biological Sciences. Costly kids have survival consequences for sheep mothers, shows new study New research published by scientists at the Moredun Research Institute and the Universities of Edinburgh, Stirling, and Lancaster shows that, for at least one population, the link between offspring and infections can have deadly consequences. Immune system discovery could aid quest for stem cell therapies A discovery of how stem cells are protected from viruses could inform the development of therapies for use in medicine, research suggests. Over 100 years of bird flu and human pandemics Human pandemic by new bird flu viruses is a continuing threat, but control measures can minimise the risks, say scientists at the Roslin Institute. University of Edinburgh leads the way on TB diagnostics The University of Edinburgh School of Chemistry is leading the way on the paradigm changing, €4.5M project to improve the rapid diagnosis of Tuberculosis. World Malaria Day 2019: A New Guide to Malaria Pharmacology On World Malaria Day 2019, a new resource is available for malaria researchers - the Guide to Malaria Pharmacology has been developed in Edinburgh to facilitate identification of new drugs to combat the disease. On World Malaria Day 2019 - celebrating malaria research at the University of Edinburgh Here we highlight some of the groundbreaking researchers based in the School of Biological Sciences at the University of Edinburgh who are tackling malaria. Applications are now open for the 2019 Moredun Foundation Award Scheme The Moredun Foundation Award Scheme supports individuals to broaden their experience and education in livestock health and welfare. University of Edinburgh part of VALUE-Dx partnership to fight antimicrobial resistance through diagnostics The University of Antwerp, bioMérieux and Wellcome Trust announce the launch of VALUE-Dx, an Innovative Medicines Initiative consortium project involving the University of Edinburgh, that will combat antimicrobial resistance and improve patient outcomes. Sepsis study to focus on genes in quest for treatments Pioneering research is to focus on the role genes play in determining how likely people are to die from infection in the hope it will speed the search for new medicines. Children’s noses hold clues to serious lung infections, study shows Microorganisms in a child’s nose could offer clues to improving the diagnosis and treatment of severe lung infections, research shows. Gene study at the Roslin Institute set to investigate how flu jumps species New study will identify genes that reduce Influenza A infection in pigs and chickens, and genes that limit the spread of the virus to people. Prof Francisca Mutapi appointed to Strategic Advisory Group of the Global Challenge Research Fund An Edinburgh scientist has been appointed to a prestigious committee that advises on a £1.5 billion UK Government research fund. Bid to beat drug resistance boosted by worldwide sewage survey Efforts to monitor the spread of antibiotic resistance worldwide could be transformed with a map created using data from analysis of sewage samples. Many congratulations to Edinburgh Infectious Diseases members Sarah Reece and Liz Grant, new Fellows of the Royal Society of Edinburgh The RSE, Scotland’s National Academy, has announced the addition of 62 new Fellows from the worlds of science, health, international development, business, creative arts, technology, law, and public engagement. Students at the University of Edinburgh discuss antimicrobial resistance during the Festival of Creative Learning The BEYOND RESISTANCE network organised two very successful workshops discussing antimicrobial resistance during the University of Edinburgh’s Festival of Creative Learning in February 2019. University of Edinburgh to host new centre of postgraduate training in Biomedical Artificial Intelligence Postgraduate programmes in artificial intelligence at the University are being supported as part of a package of funding announced by the UK Government. Edinburgh researchers showcase AMR research in the UK parliament A group of academics from the University of Edinburgh has taken part in a Q&A highlighting how research is tacking the challenge of AMR in the UK parliament. Deforestation linked to changes in spread of infectious diseases Deforestation and land use changes impact the spread of infectious diseases, research suggests. African experts join forces to beat tropical infectious diseases Millions of people are set to benefit from four projects that aim to improve health in Sub-Saharan Africa. University of Edinburgh researchers lead on £2.5 million grant to support appropriate antibiotic prescribing Professor Aziz Sheikh in the Usher Institute for Population Health Sciences and Informatics is leading a major new initiative to tackle antibiotic over-prescribing in the UK. International Veterinary Vaccinology Network has issued new call for funding applications The calls from the IVVN for Laboratory Exchange Award applications and IVVN Pump-Priming Grant applications are now open. The deadline for all applications is Monday 15 April 2019. Scottish consortiums take giant leap forward for salmon gill health Two research consortiums, co-funded by the Scottish Aquaculture Innovation Centre, will explore diseases affecting farmed salmon and how to prevent them. Researchers at Edinburgh Napier University awarded £400K to assess novel approach to combatting dengue virus infection The research has been funded by a grant by the Medical Research Council and the Ristekdikti Government body in Indonesia, where dengue virus is endemic. Universities of Edinburgh and Glasgow to offer joint research schemes for postgraduate students The Universities of Edinburgh and Glasgow are to launch their first joint postgraduate research programmes in September. This article was published on 2024-08-28