Research focus: April 2023 - from Avian flu to equitable global health

A digest of the publication highlights from across the Edinburgh Infectious Diseases network over the past month.

Comparative Analysis of Different Inbred Chicken Lines Highlights How a Hereditary Inflammatory State Affects Susceptibility to Avian Influenza Virus

Bryson KJ, Sives S, Lee HM, Borowska D, Smith J, Digard P, Vervelde L., Viruses. 2023 Feb 21;15(3):591. doi: 10.3390/v15030591.

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Understanding host response to infectious salmon anaemia virus in an Atlantic salmon cell line using single-cell RNA sequencing

Gervais O, Peñaloza C, Gratacap R, Papadopoulou A, Beltrán M, Henderson NC, Houston RD, Hassan MA, Robledo D., BMC Genomics. 2023 Mar 29;24(1):161. doi: 10.1186/s12864-023-09254-z.

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Evolution and immunopathology of chikungunya virus informs therapeutic development

Henderson Sousa F, Ghaisani Komarudin A, Findlay-Greene F, Bowolaksono A, Sasmono RT, Stevens C, Barlow PG., Dis Model Mech. 2023 Apr 1;16(4):dmm049804. doi: 10.1242/dmm.049804.

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Adeno-associated virus 2 infection in children with non-A-E hepatitis

Ho A, Orton R, Tayler R, et al, Nature. 2023 Mar 30. doi: 10.1038/s41586-023-05948-2. Online ahead of print.

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Exploring the self-preparedness of frontline healthcare workers in an LMIC  from a humanitarian context during the COVID-19 pandemic

Khan F, Azad TB, Bhuyian S, Karim H, Grant L., Front Public Health. 2023 Mar 27;11:1043050. doi: 10.3389/fpubh.2023.1043050. eCollection 2023.

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What does equitable global health research and delivery look like? Tackling Infections to Benefit Africa partnership as a case study

Mutapi F, Banda G, Woolhouse M., BMJ Glob Health. 2023 Mar;8(3):e011028. doi: 10.1136/bmjgh-2022-011028.

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SARS-CoV-2 antibody responses associate with sex, age and disease severity in previously uninfected people admitted to hospital with COVID-19

Parker E, Thomas J, Roper KJ, et al. Front Immunol. 2023 Mar 15;14:1146702. doi: 10.3389/fimmu.2023.1146702. eCollection 2023.

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Secrets of the Hospital Underbelly: Patterns of Abundance of AMR Genes in Hospital Wastewater

Perry MR, Lepper HC, McNally L, Wee BA, Munk P, Warr A, Moore B, Kalima P, Philip C, de Roda Husman AM, Aarestrup FM, Woolhouse MEJ, van Bunnik BAD., Front Microbiol. 2021 Sep 10;12:703560. doi: 10.3389/fmicb.2021.703560. eCollection 2021.

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Amplification-free electrochemical biosensor detection of circulating microRNA to identify drug-induced liver injury

Roychoudhury A, Dear JW, Kersaudy-Kerhoas M, Bachmann TT., Biosens Bioelectron. 2023 Apr 5;231:115298. doi: 10.1016/j.bios.2023.115298.

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Progress towards dog-mediated rabies elimination in PR China: a scoping review

Shen T, Welburn SC, Sun L, Yang GJ., Infect Dis Poverty. 2023 Apr 6;12(1):30. doi: 10.1186/s40249-023-01082-3.

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Efficacy of Phase I and Phase II Coxiella burnetii Bacterin Vaccines in a Pregnant Ewe Challenge Model

Williams-Macdonald SE, Mitchell M, Frew D, Palarea-Albaladejo J, Ewing D, Golde WT, Longbottom D, Nisbet AJ, Livingstone M, Hamilton CM, Fitzgerald SF, Buus S, Bach E, Dinkla A, Roest HJ, Koets AP, McNeilly TN., Vaccines (Basel). 2023 Feb 22;11(3):511. doi: 10.3390/vaccines11030511.

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