Non-conventional T cells in health and disease

Non-conventional T lymphocytes are cells of the immune system that bridge the innate and adaptive immune system and are important sentinels against pathogens at mucosal surfaces.

These non-conventional T cells are not restricted by classical MHC and include mucosal-associated invariant T (MAIT), gamma delta γδ and natural killer (NK) T cells. They display several features associated with innate immune cells and are rapidly activated by recognition of conserved, stress-induced, self, and microbial ligands. 

We will bring together experts in mouse, farm animal and human immunology to discuss the role of these cells in health and disease.

Registration

Meeting details and registration

BSI members -  £50 Non-members - £75

Please note that there are VVN funded ECR travel scholarships to the value to £150 to support attendance to this meeting. 

The deadline has been extended to 4pm on Sunday 9 December 2018. 

ECR travel scholarship information

Programme

08:15 - 09:00 Registration and welcome tea and coffee

Immune surveillance by γδ, MHC-E restricted and iNK cells (part 1)

09:00 Cynthia Baldwin (University of Massachusetts Amhurst, USA) - Bovine γδ T-cell

09:30 Adrian Smith (University of Oxford, UK) - Avian γδ T-cell

10:00 Adrian Hayday (Francis Crick Institute, UK) - Development and regulation of γδ

10:30 Ben Wilcox (University of Birmingham, UK) - γδ cells in disease

11:00 – 11:30:  Tea/coffee

Immune surveillance by γδ,  MHC-E restricted and iNK cells (part 2)

11:30 Janice Telfer (University of Massachusetts Amhurst, USA) - Bovine γδ T-cells

12:00 Andrew McMichael (University of Oxford, UK) - MHC-E restricted cells

12:30 Patricia Barral (Francis Crick Institute, UK) - iNKT and microbiota

13:00 – 14:00: Lunch

NK cells in health and disease

14:00 Kerstin Mair (University of Veterinary Medicine Vienna, Austria) - Porcine NK cells

14:30 Dimitra Peppa (University of Oxford, UK) - NK cells in HIV

15:00 Jayne Hope (Roslin Institute, UK) - Bovine NK cells in tuberculosis

15:30 – 16:00: Tea/coffee

MAIT cells across species

16:00 Paul Klenerman (University of Oxford, UK) - Human and mouse MAITs

16:30 Olivier Lantz (Institut Curie, France) - MAITs cells across species

17:00 Mariolina Salio (University of Oxford, UK) - MAITs

Close

17:30: Wrap up – closing remarks