Research in this theme is investigating the molecular and cellular nature of the virulence factors by which pathogens target their hosts. Major projects are addressing the molecular basis of host-pathogen interactions, how these interaction cause pathology, immune responses and disease transmission, and how this knowledge can exploited therapeutically. Researchers contributing to the theme NameInterestAffiliationEmailRosalind J AllenBiological & Soft Condensed Matter PhysicsSchool of Physics & AstronomyFormer memberPip BeardPoxviruses modulation & pathogenesisRoslin Institute / R(D)SVSpip.beard@ed.ac.ukClare BlackburnDevelopmental immunology & LeishmaniaSchool of Biological Sciencesc.blackburn@ed.ac.ukGarry BlakelyAnaerobic bacteria of the gastrointestinal tractSchool of Biological SciencesGarry.Blakely@ed.ac.ukJanice BramhamStructural biology & complementSchool of Biological Sciencesjbramham@staffmail.ed.ac.ukAidan BrownPhysics of bacterial motility, adhesion, growth, and interaction with bacteriophagesSchool of Physics and Astronomyabrown20@staffmail.ed.ac.ukSusan DewarPathogenicity determinants of Acrobacter speciesHeriot Watt Universitys.j.dewar@hw.ac.ukMeriem El KarouiRole of DNA maintenance process on bacterial growth & evolutionSchool of Biological SciencesMeriem.Elkaroui@ed.ac.ukRoss FitzgeraldEvolution & pathogenesis of StaphylococciRoslin InstituteRoss.Fitzgerald@ed.ac.ukAndrew FreeMicrobial communities and their applications in biotechnology and medicineSchool of Biological SciencesAndrew.Free@ed.ac.ukMaurice GallagherBacterial pathogens and microbial technologySchool of Biological SciencesMP.Gallagher@ed.ac.ukDavid GallyBacterial zoonotic diseasesRoslin Institutedgally@ed.ac.ukSander GrannemanRole of non-coding RNAs and RNA-binding proteins in controlling rapid adaptive responses in pathogenic bacteriaCentre for Synthetic and Systems Biologysgrannem@staffmail.ed.ac.ukAndrew GillPrions & protein misfoldingRoslin Instituteandy.gill@roslin.ed.ac.ukLinda GilmoreDrug discovery against trypanosomatid parasitesSchool of Biological Scienceslinda.gilmore@ed.ac.ukFinn GreyViral micro-RNA functionRoslin Institutefinn.grey@roslin.ed.ac.ukDavid GriffithsPathogenesis of respiratory viruses of livestockMoredun Research Institutedavid.griffiths@moredun.ac.ukElisabeth InnesProtozoal parasites and animal healthMoredun Research Institutelee.innes@moredun.ac.ukTom LittleEvolutionary biology of host-parasite interactionsSchool of Biological SciencesTom.Little@ed.ac.ukNicola LynskeyUnderstanding gene regulation in pathogenic streptococciRoslin Institutenicola.lynskey@roslin.ed.ac.ukJean MansonProtein misfolding diseases, including dementias & prion diseasesCentre for dementia prevention Jacqui MatthewsDirector of Veterinary ScienceAustin Davis Biologics Ltd Keith MatthewsTrypanosome biology & developmentSchool of Biological Scienceskeith.matthews@ed.ac.ukPaul MichelsMetabolism of trypanosomatid parasites and drug discoverySchool of Biological Sciencespaul.michels@ed.ac.ukDavide MichielettoRole of DNA topology enzymes in chromatin organisationSchool of Physics & Astronomydavide.michieletto@ed.ac.ukDonald MorrisonEpidemiology of antibiotic resistant hospital pathogens in the non-clinical environmentEdinburgh Napier Universityd.morrison2@napier.ac.ukIvan MorrisonTheileria genetics & immunologyRoslin Instituteivan.morrison@ed.ac.ukMaddie MouleThe host-pathogen interactions of bacterial diseases that cause a threat to global healthSchool of Biological Sciencesmaddie.moule@ed.ac.ukDan NusseyImmune variation in wild populationsSchool of Biological Sciencesdan.nussey@ed.ac.ukDarren ObbardDrosphila viruses and antiviral defencesSchool of Biological Sciencesdarren.obbard@ed.ac.ukGavin PatersonMolecular and Applied MicrobiologyRoslin Institutegavin.paterson@ed.ac.ukTeuta PilizotaEffects of osmotic changes on bacterial growth and survivalSchool of Biological Sciencesteuta.pilizota@ed.ac.ukAnura RambukkanaBacterial-induced host cell reprogrammingScottish Centre for Regenerative Medicinea.rambuka@ed.ac.ukNeil SargisonRuminant helminth control and anthelmintic resistanceRoslin Instituteneil.sargison@ed.ac.ukThamarai SchneidersMechanisms of antimicrobial resistanceInfection MedicineThamarai.Schneiders@ed.ac.ukColin SharpNew and emerging virusesEdinburgh Genomicscsharp4@staffmail.ed.ac.ukNuno SilvaAntimicrobial Resistance in livestock & Novel antimicrobial agentsMoredun Research Institutenuno.silva@moredun.ac.ukRichard SloanIntracellular innate immunity & retrovirusesInfection Medicinerichard.sloan@ed.ac.ukDavid SmithMolecular basis of parasite invasion and persistenceMoredun Research Instituted.smith@moredun.ac.ukStephen SpoelMolecular plant immunitySchool of Biological Sciencessteven.spoel@ed.ac.ukPieter Steketee Roslin InstitutePieter.Steketee@ed.ac.ukMark StevensMolecular virulence of bacterial pathogensRoslin InstituteMark.Stevens@roslin.ed.ac.ukJo StevensCell biology of BurkholderiaRoslin InstituteJo.Stevens@roslin.ed.ac.ukChristine Tait-Burkhard Roslin InstituteChristine.Burkard@roslin.ed.ac.ukSimon TalbotPathogenesis and therapy of virus infectionsInfection MedicineS.Talbot@ed.ac.ukJose Vazquez-BolandBacterial intracellular pathogensRoslin Institutev.boland@ed.ac.ukPrerna VohraLecturer in MicrobiologySchool of Biological Sciencesprerna.vohra@ed.ac.ukBartek WaclawBiophysics-microbial evolution and CancerSchool of Physics and Astronomybwaclaw@staffmail.ed.ac.uk This article was published on 2025-07-07