Molecular pathogenesis

Research in this theme is investigating the molecular and cellular nature of the virulence factors by which pathogens target their hosts. Major projects are addressing the molecular basis of host-pathogen interactions, how these interaction cause pathology, immune responses and disease transmission, and how this knowledge can exploited therapeutically.

Researchers contributing to the theme

Name

Interest

Affiliation

Email

Rosalind J AllenBiological & Soft Condensed Matter PhysicsSchool of Physics & AstronomyFormer member
Pip BeardPoxviruses modulation & pathogenesisRoslin Institute / R(D)SVSpip.beard@ed.ac.uk
Clare BlackburnDevelopmental immunology & LeishmaniaSchool of Biological Sciencesc.blackburn@ed.ac.uk
Garry BlakelyAnaerobic bacteria of the gastrointestinal tractSchool of Biological SciencesGarry.Blakely@ed.ac.uk
Janice BramhamStructural biology & complementSchool of Biological Sciencesjbramham@staffmail.ed.ac.uk
Aidan BrownPhysics of bacterial motility, adhesion, growth, and interaction with bacteriophagesSchool of Physics and Astronomyabrown20@staffmail.ed.ac.uk
Susan DewarPathogenicity determinants of Acrobacter speciesHeriot Watt Universitys.j.dewar@hw.ac.uk
Meriem El KarouiRole of DNA maintenance process on bacterial growth & evolutionSchool of Biological SciencesMeriem.Elkaroui@ed.ac.uk
Ross FitzgeraldEvolution & pathogenesis of StaphylococciRoslin InstituteRoss.Fitzgerald@ed.ac.uk
Andrew FreeMicrobial communities and their applications in biotechnology and medicineSchool of Biological SciencesAndrew.Free@ed.ac.uk
Maurice GallagherBacterial pathogens and microbial technologySchool of Biological SciencesMP.Gallagher@ed.ac.uk
David GallyBacterial zoonotic diseasesRoslin Institutedgally@ed.ac.uk
Sander GrannemanRole of non-coding RNAs and RNA-binding proteins in controlling rapid adaptive responses in pathogenic bacteriaCentre for Synthetic and Systems Biologysgrannem@staffmail.ed.ac.uk
Andrew GillPrions & protein misfoldingRoslin Instituteandy.gill@roslin.ed.ac.uk
Linda GilmoreDrug discovery against trypanosomatid parasitesSchool of Biological Scienceslinda.gilmore@ed.ac.uk
Finn GreyViral micro-RNA functionRoslin Institutefinn.grey@roslin.ed.ac.uk
David GriffithsPathogenesis of respiratory viruses of livestockMoredun Research Institutedavid.griffiths@moredun.ac.uk
Elisabeth InnesProtozoal parasites and animal healthMoredun Research Institutelee.innes@moredun.ac.uk
Tom LittleEvolutionary biology of host-parasite interactionsSchool of Biological SciencesTom.Little@ed.ac.uk
Nicola LynskeyUnderstanding gene regulation in pathogenic streptococciRoslin Institutenicola.lynskey@roslin.ed.ac.uk
Jean MansonProtein misfolding diseases, including dementias & prion diseasesCentre for dementia prevention 
Jacqui MatthewsDirector of Veterinary ScienceAustin Davis Biologics Ltd 
Keith MatthewsTrypanosome biology & developmentSchool of Biological Scienceskeith.matthews@ed.ac.uk
Paul MichelsMetabolism of trypanosomatid parasites and drug discoverySchool of Biological Sciencespaul.michels@ed.ac.uk
Davide MichielettoRole of DNA topology enzymes in chromatin organisationSchool of Physics & Astronomydavide.michieletto@ed.ac.uk
Donald MorrisonEpidemiology of antibiotic resistant hospital pathogens in the non-clinical environmentEdinburgh Napier Universityd.morrison2@napier.ac.uk
Ivan MorrisonTheileria genetics & immunologyRoslin Instituteivan.morrison@ed.ac.uk
Maddie MouleThe host-pathogen interactions of bacterial diseases that cause a threat to global healthSchool of Biological Sciencesmaddie.moule@ed.ac.uk
Dan NusseyImmune variation in wild populationsSchool of Biological Sciencesdan.nussey@ed.ac.uk
Darren ObbardDrosphila viruses and antiviral defencesSchool of Biological Sciencesdarren.obbard@ed.ac.uk
Gavin PatersonMolecular and Applied MicrobiologyRoslin Institutegavin.paterson@ed.ac.uk
Teuta PilizotaEffects of osmotic changes on bacterial growth and survivalSchool of Biological Sciencesteuta.pilizota@ed.ac.uk
Anura RambukkanaBacterial-induced host cell reprogrammingScottish Centre for Regenerative Medicinea.rambuka@ed.ac.uk
Neil SargisonRuminant helminth control and anthelmintic resistanceRoslin Instituteneil.sargison@ed.ac.uk
Thamarai SchneidersMechanisms of antimicrobial resistanceInfection MedicineThamarai.Schneiders@ed.ac.uk
Colin SharpNew and emerging virusesEdinburgh Genomicscsharp4@staffmail.ed.ac.uk
Nuno SilvaAntimicrobial Resistance in livestock & Novel antimicrobial agentsMoredun Research Institutenuno.silva@moredun.ac.uk
Richard SloanIntracellular innate immunity & retrovirusesInfection Medicinerichard.sloan@ed.ac.uk
David SmithMolecular basis of parasite invasion and persistenceMoredun Research Instituted.smith@moredun.ac.uk
Stephen SpoelMolecular plant immunitySchool of Biological Sciencessteven.spoel@ed.ac.uk
Pieter Steketee Roslin InstitutePieter.Steketee@ed.ac.uk
Mark StevensMolecular virulence of bacterial pathogensRoslin InstituteMark.Stevens@roslin.ed.ac.uk
Jo StevensCell biology of BurkholderiaRoslin InstituteJo.Stevens@roslin.ed.ac.uk
Christine Tait-Burkhard Roslin Institute
Simon TalbotPathogenesis and therapy of virus infectionsInfection MedicineS.Talbot@ed.ac.uk
Jose Vazquez-BolandBacterial intracellular pathogensRoslin Institutev.boland@ed.ac.uk
Prerna VohraLecturer in MicrobiologySchool of Biological Sciencesprerna.vohra@ed.ac.uk
Bartek WaclawBiophysics-microbial evolution and CancerSchool of Physics and Astronomybwaclaw@staffmail.ed.ac.uk