Pathogen Biology and Host-Pathogen Interactions

This theme uncovers the molecular and cellular mechanisms of pathogenesis, from pathogen virulence strategies to host signalling, inflammation and tissue responses. Evolutionary and ecological perspectives reveal how selection pressures and within‑ and between‑host dynamics shape infection trajectories. 

The microbiome in health and disease is investigated alongside immunology across the life course, linking developmental stage, ageing and immune heterogeneity to outcomes. 

Antimicrobial resistance mechanisms are mapped to inform stewardship and the design of new countermeasures. These mechanistic insights provide a foundation for next‑generation diagnostics, therapeutics and vaccines that remain effective amid biological diversity and resistance.